First, you need to add new url pattern to your root urls.py file. You can replace r'^RPC2$' with anything you like.

# urls.py 

urlpatterns = patterns('', 
    # rpc4django will need to be in your Python path  
    (r'^RPC2$', 'rpc4django.views.serve_rpc_request'), 
)

Second, add RPC4Django to the list of installed applications in your settings.py.

# settings.py 

INSTALLED_APPS = ( 
    'rpc4django', 
)

Lastly, you need to let RPC4Django know which methods to make available. RPC4Django recursively imports all the apps in INSTALLED_APPS and makes any methods importable via __init__.py with the @rpcmethod decorator available as RPC methods. You can always write your RPC methods in another module and simply import it in __init__.py.

# testapp/__init__.py 
from rpc4django import rpcmethod 

# The doc string supports reST if docutils is installed
@rpcmethod(name='mynamespace.add', signature=['int', 'int', 'int']) 
def add(a, b):
    '''Adds two numbers together
    >>> add(1, 2)  
    3  
    '''

    return a+b