Python Implementations of algorithms found in: Estimating Continuous Time Transition Matrices From Discretely Observed Data Yasunari Inamura* yasunari.inamura@boj.or.jp
If you have specific needs or use cases for these algorithms feel free to contact me directly.
In addition there are a few alternative and novel algorithms implemented. My specific use case was MFEP predictions in chemistry, but the markovian models apply in many fields.