>>> import sass
>>> sass.compile_string("div { a { color: black}}")
'div a {\n  color: black; }\n'

pip install sass

Tested with Python 2.7 and Python 3.2/3.3

Steps to compile and install:

sudo pip install Cython
git submodule init
git submodule update
make
sudo python setup.py develop

If you want to use an alternate python, you'll have to edit the Makefile or execute those commands from activated virtualenv.

It is easy. Fork repo on GitHub, fix stuff and send me nice looking pull-request.