irvin.FADD_to_C8() irvin.NFkB_cFlip_interaction() #3 irvin.cFLIP_L_Bid_interaction() #4 irvin.RIP1_Hypothesis_1()#5 irvin.ComplexI_to_NFkB() irvin.ComplexII_Hypothesis_1() #5 irvin.RIP1_deubiqutination_Hypothesis_1()#5 irvin.RIP1_to_SecondaryComplex() irvin.RIP1_truncation() irvin.Bid_Hypothesis() #6 irvin.C8_catalyzed_truncations() irvin.rip1_to_MLKL() irvin.C3_inhibits_MLKL()#7 # From lopez_modules lopez.declare_initial_conditions() lopez.translocate_tBid_Bax_BclxL() lopez.tBid_activates_Bax_and_Bak() lopez.tBid_binds_all_anti_apoptotics() lopez.sensitizers_bind_anti_apoptotics() lopez.effectors_bind_anti_apoptotics() lopez.lopez_pore_formation(do_pore_transport=True) # From albeck_modules albeck.pore_to_parp() # Observables irvin.observables()
mtor_modules.mtorc1_signaling() mtor_modules.mtorc2_signaling() mtor_modules.tsc2_monomers() mtor_modules.tsc2_initial() mtor_modules.tsc2_inhibition_by_akt() mtor_modules.tsc2_inhibition_by_erk() mtor_modules.tsc2_activation_by_erk() mtor_modules.tsc2_gap_function() # ## Apoptotic signaling albeck_modules.ligand_to_c8_monomers() apoptosis_modules.apoptosis_monomers() apoptosis_modules.apoptosis_initial() albeck_modules.apaf1_to_parp_monomers() lopez_modules.translocate_tBid_Bax_BclxL() lopez_modules.tBid_activates_Bax_and_Bak() lopez_modules.effector_auto_activation() lopez_modules.tBid_binds_all_anti_apoptotics() lopez_modules.effectors_bind_anti_apoptotics() lopez_modules.sensitizers_bind_anti_apoptotics() lopez_modules.lopez_pore_formation() apoptosis_modules.apoptosis_sensitizer_translocation() apoptosis_modules.apoptosis_bim_and_puma_bind_anti_apoptotics() apoptosis_modules.apoptosis_bim_activate_bax() albeck_modules.pore_to_parp() ## Crosstalk between MAPK and AKT pathways crosstalk_modules.crosstalk_mapk_akt_monomers() crosstalk_modules.crosstalk_mapk_akt_initial() crosstalk_modules.crosstalk_mapk_akt_events() #
irvin.FADD_to_C8() irvin.cFlip_competitive_inhibition() #2 irvin.NFkB_cFlip_interaction() #3 irvin.cFLIP_L_Bid_interaction() #4 irvin.RIP1_Hypothesis_2() #5 irvin.ComplexI_to_NFkB() irvin.ComplexII_Hypothesis_2() #5 irvin.TRADD_RIP1unmod_Hypothesis_2() #5a irvin.RIP1_deubiqutination_Hypothesis_1() #5a irvin.RIP1_to_SecondaryComplex() irvin.RIP1_truncation() irvin.Bid_Hypothesis() #6 irvin.C8_catalyzed_truncations() irvin.rip1_to_MLKL() irvin.C3_inhibits_MLKL() #7 # From lopez_modules lopez.declare_initial_conditions() lopez.translocate_tBid_Bax_BclxL() lopez.tBid_activates_Bax_and_Bak() lopez.tBid_binds_all_anti_apoptotics() lopez.sensitizers_bind_anti_apoptotics() lopez.effectors_bind_anti_apoptotics() lopez.lopez_pore_formation(do_pore_transport=True) # From albeck_modules albeck.pore_to_parp() # Observables irvin.observables()
chen_modules.mtorc1_signaling() chen_modules.mtorc2_signaling() chen_modules.tsc2_monomers() chen_modules.tsc2_initial() chen_modules.tsc2_inhibition_by_akt() chen_modules.tsc2_inhibition_by_erk() chen_modules.tsc2_activation_by_erk() chen_modules.tsc2_gap_function() # Apoptotic signaling albeck_modules.ligand_to_c8_monomers() chen_modules.apoptosis_monomers() chen_modules.apoptosis_initial() albeck_modules.apaf1_to_parp_monomers() lopez_modules.translocate_tBid_Bax_BclxL() lopez_modules.tBid_activates_Bax_and_Bak() lopez_modules.effector_auto_activation() lopez_modules.tBid_binds_all_anti_apoptotics() lopez_modules.effectors_bind_anti_apoptotics() lopez_modules.sensitizers_bind_anti_apoptotics() lopez_modules.lopez_pore_formation() chen_modules.apoptosis_sensitizer_translocation() chen_modules.apoptosis_bim_and_puma_bind_anti_apoptotics() chen_modules.apoptosis_bim_activate_bax() albeck_modules.pore_to_parp() # Crosstalk between MAPK and AKT pathways chen_modules.crosstalk_mapk_akt_monomers() chen_modules.crosstalk_mapk_akt_initial() chen_modules.crosstalk_mapk_akt_events()
