Algorithm to estimate the significance of a mutual exclusive pattern or co-occurrence
This python implementation has a citable DOI from Zenodo. Click on the badge for different citation styles:
The MutEx algorithm is described in detail in the PhD Thesis "Analysis and visualization of multidimensional cancer genomics data" : http://www.tdx.cat/handle/10803/301436. The same algorithm is also implemented and directly usable in the Gitools software package: http://www.gitools.org
The algorithm itself has first been used in the following publication: Rubio-Perez, Tamborero, Schroeder, Antolín, Deu-Pons, Perez-Llamas, Mestres, Gonzalez-Perez and Lopez-Bigas. In Silico Prescription of Anticancer Drugs to Cohorts of 28 Tumor Types Reveals Targeting Opportunities
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scipy 0.17 or higher
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pandas 0.17 or higher
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numpy 1.10.4
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joblib
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multiprocessing