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Metastasis

A hybrid model for cancer metastasis implemented in CompuCell3D. The model incorporates the genetic, cellular and macroscopic aspects of tumor growth to give an unparalleled insight into the nature of metastasis.

CompuCell3D (CC3D)

Academic package for tissue simulations. A very versatile package with many parameters. Allows us to use python to execute highly custom scripts at different timesteps.

cc3dtools

Custom library developed to extend the functionality of CC3D. It has the following packages:

  1. Genome - used to simulate genomes of cells.

  2. GenomeComapre and GenomeCompare2 - used to compare and visualize multiple Genome objects

  3. Lineage - allows us to track the histories of cells and to create newick representations and plot them

  4. Tracker - used to track divisions, allos us to save as you go or stash and then save them at the end.

Administrative Details

  • Supervisor: Dr. Simon Gravel (@sgravel)
  • Student: Mr. Zafarali Ahmed (@zafarali)
  • Funding Agency: Canadian Institutes of Health Research (CIHR) Summer Studentship Award for Computational Biology (Cancer)
  • Location of Work: McGill University, Montreal, Quebec, Canada

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A hybrid model for cancer metastasis.

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