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Structure and Landscapes

Description

This Python project investigates the effect population structure has on organisms with smooth or rugged adaptive landscapes. Various sequence to fitness mappings will be explored including:

  • RNA secondary structure
  • Simple Integer Model
  • Bitstrings
  • Kauffman's N-K Model

Authors

* Joseph Henry Rochlin Marcus .. _Jared Carlson-Stevermer : jmcs@utexas.edu .. _Joseph Henry Rochlin Marcus : josephhmarcus@gmail.com .. _Joshua Nahum : josh@nahum.us

Github Repositories

  • git://github.com/jaredc-s/structure_and_landscapes.git
  • git://github.com/jhmarcus/structure_and_landscapes.git
  • git://github.com/nahumj/structure_and_landscapes.git

Requirements

Mandatory

  • Python 2.7

Optional

  • Ned Batchelder's coverage.py
  • Nose
  • Pep8
  • Numpy
  • Matplotlib

Install

1)github: https://github.com/jhmarcus/structure-and-landscapes 2)downloads https://github.com/jhmarcus/structure-and-landscapes/downloads 3)download as zip using the defult archive manager 4)sudo apt-get install python2.7-dev - version python2.7-dev (2.7.3-0ubuntu3) 5)sudo apt-get install build-essential - version build-essential (11.5ubuntu2) 6)sudo apt-get install pep8 7) pep8 's version (0.6.1-2ubuntu2) 8) sudo apt-get install python-pip 9) pip version (1.0-1build1)

Runsnakerun

http://www.vrplumber.com/programming/runsnakerun/

depedencies for runsnakerun apt-get install python-profiler python-wxgtk2.8 python-setuptools

ViennaRNA

http://www.tbi.univie.ac.at/~ivo/RNA/ http://www.tbi.univie.ac.at/~ronny/RNA/vrna2_source.html

follow instructions on install ./configure make sudo make install

version 2.0.7 download source code and use the default archive manager!

Add this package to PYTHONPATH

Add this line to ~/.bashrc:

export PYTHONPATH=$PYTHONPATH:$PATH_TO_DIRECTORY_CONTAINING_structure_and_landscape

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