$ pip install cymysql
$ pip install django-cymysql

mysql> create database some_what_database default character set utf8;

DATABASES = {
    'default': {
        'ENGINE': 'mysql_cymysql',
        'NAME': 'some_what_database',
        'HOST': ...,
        'USER': ...,
        'PASSWORD': ...,
    }
}

SOUTH_DATABASE_ADAPTERS = {
    'default': "south.db.mysql"
}