This is a modified version of the caspase model based on Albeck2008. The implemented modifications have been published in Corbat2018.

Albeck2008: Albeck JG, Burke JM, Spencer SL, Lauffenburger DA, Sorger PK (2008) Modeling a Snap-Action, Variable-Delay Switch Controlling Extrinsic Cell Death. PLOS Biology 6(12): e299.

Corbat2018: Corbat AA, Schuermann KC, Liguzinski P , Radon Y, Bastiaens PIH, Verveer PJ, Grecco HE, (2018) Co-imaging extrinsic, intrinsic and effector caspase activity by fluorescence anisotropy microscopy, Redox Biology, Volume 19, Pages 210-217

Code style is enforced through pre-commit hooks. Install them with:

pip install pre-commit
pre-commit install