Transliteration module provides way to transliterate from English to any Indian Language or from any Indian Language other Indian Language. This module is originally part of SILPA, and currently separated as part of restructuring.

from transliteration import getInstance
t = getInstance()
text = u"ನಮಸ್ಕಾರ"
t_text = t.transliterate(text, "ml_IN")
print t_text #"നമസ്കാര"

for more read the docs