$ sudo pip install --pre xmpppy  # xmpppy is tagged as an "rc" version
$ sudo pip install otrxmppchannel

import time
from otrxmppchannel import OTRXMPPChannel
from otrxmppchannel.connection import OTR_TRUSTED, OTR_UNTRUSTED,
    OTR_UNENCRYPTED, OTR_UNKNOWN

# Load the base64-encoded OTR DSA key. Constructing the object without
# a key will generate one and provide it via ValueError exception.
privkey = open('.otrprivkey', 'r').read()

class MyOTRChannel(OTRXMPPChannel):
    def on_receive(self, message, from_jid, otr_state):
        if otr_state == OTR_TRUSTED:
            state = 'trusted'
        elif otr_state == OTR_UNTRUSTED:
            state = 'UNTRUSTED!'
        elif otr_state == OTR_UNENCRYPTED:
            state = 'UNENCRYPTED!'
        else:
            state = 'UNKNOWN OTR STATUS!'
        print('received %s from %s (%s)' % (message, from_jid, state))

mychan = MyOTRXMPPChannel(
    'bradass87@jabber.ccc.de/datadiode',
    'supersecret',
    [
        (
            'mendax@jabber.wikileaks.org',
            '33eb6b01c97ceba92bd6b5e3777189c43f8d6f03'
        ),
        'esnowden@chat.nsa.gov'
    ],
    privkey
)

mychan.send('')  # Force OTR setup
time.sleep(3)  # Wait a bit for OTR setup to complete
mychan.send('This message should be encrypted')