Exemplo n.º 1
0
rho_per_locus=100.0
f=qtm.MlocusAdditiveTrait()
delmuts=[1e-3]*NLOCI
mmodels=[fp.GaussianS(0,1,1,0.25)]*len(delmuts)
for i in mmodels:
    print i
nmuts=[theta_neutral/float(4*nlist[0])]*NLOCI
recrates=[theta_neutral/float(4*nlist[0])]*NLOCI

pfile = gzip.open("pickle_out.p","wb")

for i in range(1):
    x = fp.MlocusPopVec(NREPS,nlist[0],NLOCI)
    sampler=fp.NothingSampler(len(x))

    qtm.evolve_qtraits_mloc_sample_fitness(rnge,x,sampler,f,
            nlist[:5000],
            nmuts,
            delmuts,
            mmodels,
            recrates,
            [0.0]*(NLOCI-1),sample=0,
            VS=2,optimum=0.)
    v = fp.view_mutations(x)
    for i in v:
        print i
    for i in x:
        d=fpio.serialize(i)
        pickle.dump(d,pfile)
pfile.close()
Exemplo n.º 2
0
# coding: utf-8

# # Example of taking 'views' from simulated populations

# In[1]:

from __future__ import print_function
import fwdpy as fp
import pandas as pd
from background_selection_setup import *

# Get the mutations that are segregating in each population:

# In[2]:

mutations = [fp.view_mutations(i) for i in pops]

# Look at the raw data in the first element of each list:

# In[3]:

for i in mutations:
    print(i[0])

# Let's make that nicer, and convert each list of dictionaries to a Pandas DataFrame object:

# In[4]:

mutations2 = [pd.DataFrame(i) for i in mutations]

# In[5]:
                         nlist,
                         mutrate_neutral,
                         mutrate_sel,
                         recrate,
                         nregions,
                         sregions,
                         recregions)

#Change a mutation's selection coefficient
for i in pops:
    x=csp.change_selection_coeff(i,0.5,10,0.1,0.25)
    #print out count and position of variant actually changed
    print (x)

#Get the list of mutations in each population
views = [pd.DataFrame(i) for i in fp.view_mutations(pops)]

for i in views:
    print (i[i.neutral==False])

#Now, lets use our custom temporal sampler
sampler=cts1.SelectedSFSSampler(len(pops))

#Evolve these pops for another 100 generations,
#tracking joint frequency,s of all selected mutations
fp.evolve_regions_sampler(rng,pops,sampler,
                          nlist[:100], 
                          mutrate_neutral,
                          mutrate_sel,
                          recrate,
                          nregions,
Exemplo n.º 4
0
# # Example of taking 'views' from simulated populations

# In[1]:

from __future__ import print_function
import fwdpy as fp
import pandas as pd
from background_selection_setup import *


# Get the mutations that are segregating in each population:

# In[2]:

mutations = [fp.view_mutations(i) for i in pops]


# Look at the raw data in the first element of each list:

# In[3]:

for i in mutations:
    print(i[0])


# Let's make that nicer, and convert each list of dictionaries to a Pandas DataFrame object:

# In[4]:

mutations2 = [pd.DataFrame(i) for i in mutations]
Exemplo n.º 5
0
rng = fp.GSLrng(101)

pops = fp.evolve_regions(rng,       #The random number generator
                         4,         #The number of pops to simulate = number of threads to use.
                         N,         #Initial population size for each of the 4 demes
                         nlist[0:], #List of population sizes over time.
                         0.005,     #Neutral mutation rate (per gamete, per generation)
                         0.01,      #Deleterious mutation rate (per gamete, per generation)
                         0.005,     #Recombination rate (per diploid, per generation)
                         nregions,  #Defined above
                         sregions,  #Defined above
                         recregions)#Defined above
##Get fixation views:
fixations = [fp.view_fixations(i) for i in pops]
##Get mutation views:
mviews = fp.view_mutations(pops)

class test_sample_details(unittest.TestCase):
    def test_CompareUsingView(self):
        """
        Evolve some population, take samples,
        get details of those samples, make sure
        those details match up what 'views' think should
        be in the population.
        """
        samples = [fp.get_samples(rng,i,100) for i in pops]
        
        details = [fp.get_sample_details(i[1],j) for i,j in zip(samples,pops)]