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GENIE Analysis

This repository contains code used to generate figures for the Project GENIE manuscript "AACR Project GENIE: 100,000 cases and beyond".

Main figures

  1. Virtual trial matching - Tali Mazor, James Lindsay, Priti Kumari, DFCI

  2. Actionable and resistant mutations - Michelle Green and Jonathan Bell, DUKE

  3. Driver mutations in rare cancers - Stephen-John Sammut, Gary Doherty, CRUK

Supplemental figures

  1. Gene-level mutation frequencies in GENIE versus TCGA - Matthew Galvin, Brady Bernard, PROV

  2. Summary of gene-level mutation frequencies - Matthew Galvin, Brady Bernard, PROV

  3. Tumors without drivers - Jeff Bruce, UHN

  4. Tumor mutation burden by contributing center and by cancer subtype - Haley Hunter-Zinck, Sage Bionetworks

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Figures for the Project GENIE manuscript "AACR Project GENIE: 100,000 cases and beyond"

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