This MH (Microhaplotype Genotyper) implements the features based on the following research paper at https://www.fsigenetics.com/article/S1872-4973(18)30391-0/abstract.

Review Forensic Sci Int Genet . 2019 Jan:38:54-69. doi: 10.1016/j.fsigen.2018.09.009. Epub 2018 Oct 1. Microhaplotypes in forensic genetics Fabio Oldoni 1, Kenneth K Kidd 2, Daniele Podini 3 Affiliations expand PMID: 30347322 DOI: 10.1016/j.fsigen.2018.09.009 Abstract Microhaplotype loci (microhaps, MHs) are a novel type of molecular marker of less than 300 nucleotides, defined by two or more closely linked SNPs associated in multiple allelic combinations. The value of these markers is enhanced by massively parallel sequencing (MPS), which allows the sequencing of both parental haplotypes at each of the many multiplexed loci. This review describes the features of these multi-SNP markers and documents their value in forensic genetics, focusing on individualization, biogeographic ancestry inference, and mixture deconvolution. Foreseeable applications also include missing person identification, relationship testing, and medical diagnostic applications. The technique is not restricted to humans.

Keywords: Biogeographic ancestry inference; Clinical application; Human identification; Massively parallel sequencing; Microhaplotypes; Missing person and relationship identification; Mixture deconvolution; Non-human DNA; Probabilistic genotyping; Single nucleotide polymorphisms.

Copyright © 2018. Published by Elsevier B.V.

PubMed Disclaimer