Please checkout the new phenotrex package, which succeeds PICA: https://github.com/univieCUBE/phenotrex

It comes with a considerable number of improvements

• Builds upon the battle-tested SciPy stack (scikit-learn, pandas, etc.)
• More easily extensible
• New classifiers (e.g. XGboost)
• Test-driven development
• Supports Python 3.7 and higher
• Available from PyPI: $ pip install phenotrex