def get_distn(cls, log_counts, codon_distn, ts, tv, syn, nonsyn, compo, asym_compo, natural_theta, ): cls.check_theta(natural_theta) nt_distn = markovutil.ratios_to_distn(natural_theta[2:5]) codon_distn = codon1994.get_f1x4_codon_distn(compo, nt_distn) return codon_distn
def get_pre_Q(cls, log_counts, codon_distn, ts, tv, syn, nonsyn, compo, asym_compo, natural_theta, ): cls.check_theta(theta) kappa = natural_theta[0] omega = natural_theta[1] nt_distn = markovutil.ratios_to_distn(theta[2:5]) codon_distn = codon1994.get_f1x4_codon_distn(compo, nt_distn) pre_Q = codon1994.get_pre_Q( ts, tv, syn, nonsyn, codon_distn, kappa, omega) return pre_Q