For the impatient: https://github.com/frenetic-lang/manual/blob/master/programmers_guide/frenetic_programmers_guide.pdf

The official documentation toolchain is LaTeX.
TeXLive 2015 (or later) package has everything you need to build.

• TeXLive for Windows installation instructions are at http://www.tug.org/texlive/acquire-netinstall.html
• TeXLive for Mac, or MacTeX, installation instructions are at https://tug.org/mactex/

Then use whatever IDE you're comfortable with (TeXshop, etc.) to run programmers_guide/frenetic_programmers_guide.tex. Alternatively, from the command line you can run:

$ cd programmers_guide
$ make

All code in the Frenetic Programmers Guide can be tested with the automatic test harness. To run:

$ cd programmers_guide/code/test
$ sudo python test_suite.py

The test takes about 15 minutes to run on a MacBook under Frenetic User VM.