The original Daaaaave algorithm is described in

Lee D, Smallbone K, Dunn WB, Murabito E, Winder CL, Kell DB, Mendes P, Swainston N (2012) "Improving metabolic flux predictions using absolute
gene expression data" BMC Syst Biol 6:73
http://dx.doi.org/10.1186/1752-0509-6-73

The algorithm was originally implemented in MatLab, but is now also available  in python.

This version was released on 19 May 14 and is available at
http://github.com/u003f/daaaaave/releases/tag/original

We are developing all aspects of the algorithm.