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Segmentation of digital fundus images using an SVM supervised ML model

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Retinal Blood Vessel Segmentation Using Line Operators and Support Vector Classification

Getting Started

Before images can be segmented, dependencies must be installed and a virtual environment should be created.

Prerequisites

Python 3.5 or greater and PIP must be installed. For installation instructions, refer to official documentation.

Clone the repository.

A virtual environment is advised when installing dependencies. In the terminal, navigate to the project directory. Run python3 -m venv venv. To activate the virtual environment, run source venv/bin/activate.

Dependencies

Dependencies are found in requirements.txt. Run pip install -r requirements.txt to install.

Running the Program

The program provides two primary functions: training the model and segmenting image pixels. A model must be trained using the former function in order to be used to segment an image in the latter function.

Arguments

All arguments apply to training and classification besides the -t argument, which determines whether the program is to train the model or use the trained model to segment an image.

The same settings should be used for kernel size and rotational resolution when training the model and segmenting an image. The best results are attained by classifying images from the same database as those used to train the model.

Symbol Name Description
i images Images to be used in training the model or an image to be classified
k kernel The neighborhood size used in line detection
r rotation Rotational resolution used in line detection
t train Instruct program to train the model
drhagis Use DR HAGIS database
p proba Train SVM as probabilistic model (longer training)
s save Save the segmented image as a PNG
d display Display the segmented image
v verbose Print all logging messages instead of only high-level information

Training the Model

Before images can be segmented, the model must be trained. This is the most time-consuming portion of running the program. To save time, several example models are included, pretrained, in the repository. These examples can be renamed model.p in order to be used in segmentation of fundus images.

To train the model, run main.py -i X -t where X is one or more image numbers. The image numbers represent the suffix of the image in the DRIVE and DR HAGIS databases, and are therefore limited to integers 0 through 40. Note that images 21 through 40 are typically used as a training set for the DRIVE database.

Training the model with a full training set of 20 images can take quite a while. The writer's machine (2nd gen. i5, 16GB RAM) required nearly 19 hours to train a binary SVM using images 21 through 40. The probabilistic model used in this repo would likely take at least twice that time on the same machine. Trainng a model using one or two images should take no more than 1.5 hours.

Segmenting Fundus Images

Only one image at a time can be supplied to be segmented. Run main.py -i X -t where X is exactly one image number. The image numbers represent the suffix of the image in the DRIVE database, and is therefore limited to integers 0 through 40. Note that images 0 through 20 are typically used as a testing set.

Set the -s and/or -d arguments to save and/or display the segmented image after classification.

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