def perturbations(rep,res, sizes):
threads=20
l=[]
# l.append(op.get()[0])
# l.append(op.get()[4::3])
l=op.get()
ll=[]
for size in sizes:
for i, _l in enumerate(l):
_lt=deepcopy(_l)
per=pl({'netw':{'size':size,
'sub_sampling':{'M1':1,
'M2':1},}},
'=',
**{'name':''})
_lt+=per
_lt+=pl({'simu':{'threads':threads}},'=')
ll.append(_lt)
return ll, threads
def get():
l = []
solution, s_mul, s_equal = get_solution_slow_GP_striatum_2()
for y in numpy.arange(1.0, -0.1, -0.25):
for z in numpy.arange(1.0, -0.1, -0.25):
x = 2.5
d = {}
for keys in s_mul:
update(solution, d, keys)
misc.dict_update(d, {'nest': {'GI_GA_gaba': {'weight': y}}})
misc.dict_update(d, {'nest': {'ST_GA_ampa': {'weight': z}}})
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
l[-1] += pl(d, '=',
**{'name': 'GIGA_' + str(y) + '_STGA_' + str(z)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
x=2.5-1.25
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
misc.dict_update(d,{'node':{'CS':{'rate': 830.}}})
misc.dict_update(d,{'nest':{'GI_ST_gaba':{'weight':0.35 }}})
l[-1]+=pl(d, '=', **{'name':'mod_ST_beta_'+str(x)})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
v0 = numpy.arange(1.25, 3.75, 0.5)
v1 = numpy.arange(2.5, 5., 0.5)
v = [[x, y] for x in v0 for y in v1]
for x, y in v:
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
misc.dict_update(d, {'nest': {'ST': {'beta_I_GABAA_1': f_beta_rm(x)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_AMPA_1': f_beta_rm(y)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_NMDA_1': f_beta_rm(y)}}})
d['node']['EA']['rate'] *= 0.7
l[-1] += pl(d, '=',
**{'name': ('mod_ST_beta_' + str(x) + '_' + str(y))})
return l
def get():
l=[];
p={'equal':{},
'mul':{}}#
for w1, w2 in [
[1., .0],
[.8, .2],
[.6, .4],
[.5, .5],
[.4, .6],
[.2, .8],
[.0, 1.],
]:
d={}
d=misc.dict_update(p['mul'], d)
l+=[pl(d, '*', **{'name':''})]
d={'nest':{
'GA_FS_gaba':{'weight':w1},
'GF_FS_gaba':{'weight':w2}
}}
d=misc.dict_update(p['equal'], d)
s='GA_{0}_GF_{1}'.format( w1, w2 )
l[-1]+=pl(d, '=', **{'name':s})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
x = 2.5 - 1.25
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
misc.dict_update(d, {'nest': {'ST': {'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate'] *= 0.7
misc.dict_update(d, {'node': {'CS': {'rate': 830.}}})
misc.dict_update(d, {'nest': {'GI_ST_gaba': {'weight': 0.35}}})
l[-1] += pl(d, '=', **{'name': 'mod_ST_beta_' + str(x)})
return l
def get():
l = []
solution = get_solution_slow_GP_striatum_2()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
for a, b in zip([200., 300., 300., 400., 500.],
[a * 0.25 for a in [0.75, 0.75, 0.5, 0.5, 0.5]]):
z = 1.2
y = 0.75
d = {}
misc.dict_update(d, solution['mul'])
misc.dict_update(d, {'node': {'CS': {'rate': y}}})
misc.dict_update(d, {'node': {'CF': {'rate': z}}})
misc.dict_update(d, {'nest': {'ST_GA_ampa': {'weight': b}}})
l += [pl(d, '*', **{'name': ''})]
d = {}
misc.dict_update(d, solution['equal'])
d['node']['EI']['rate'] *= y
d['node']['EA']['rate'] = a
misc.dict_update(d, {'nest': {'GI': {'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1] += pl(d, '=',
**{'name': 'all_EIEACS_' + str(a) + '_STGAw_' + str(b)})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
d = {}
for x in numpy.arange(3.4, 6, 0.4):
# x=3.4
y = 2.25
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
print f_beta_rm(x)
misc.dict_update(d, {'nest': {'ST': {'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_NMDA_1': f_beta_rm(x)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_GABAA_1': f_beta_rm(y)}}})
# d['node']['EA']['rate']*=0.7
l[-1] += pl(
d, '=',
**{'name': 'mod_CS_STbeta_' + str(x) + '_GA_STbeta_' + str(y)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution_slow_GP_striatum()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
d={}
for x in numpy.arange(3.4, 6, 0.4):
# x=3.4
y=2.25
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_GABAA_1': f_beta_rm(y)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'mod_CS_STbeta_'+str(x)+'_GA_STbeta_'+str(y)})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution_slow_GP_striatum()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
for y in numpy.arange(0.9, 0.0, -0.2):
x = 2.5
d = {}
for keys in s_mul:
update(solution, d, keys)
misc.dict_update(d, {'conn': {'nest': {'GI_GA_gaba': {'weight': y}}}})
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
misc.dict_update(d, {'nest': {'ST': {'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate'] *= 0.7
l[-1] += pl(d, '=', **{'name': 'mod_ST_beta_' + str(x)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
# Decrease/increase C1,C2,CF,CS, EI and EA. Test idea that at
# slow wave cortical and thalamic input is decreased.
mod=numpy.arange(0.5, 1.5, 0.05)
for x in mod:
d={}
for keys in s_mul: update(solution, d, keys)
misc.dict_update(d, {'node':{'CF':{'rate':x}}} )
misc.dict_update(d, {'node':{'CS':{'rate':x}}} )
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
d['node']['C1']['rate']*=x
d['node']['C2']['rate']*=x
d['node']['EI']['rate']*=x
d['node']['EA']['rate']*=x
l[-1]+=pl(d, '=', **{'name':'mod_C1_C2_CF_CS_EI_EA_'+str(x)})
return l
def perturbations(rep, res):
threads = 2
l = []
# l.append(op.get()[0])
l.append(op3.get()[3])
ll = []
p_sizes = [0.1989460102, 0.1608005821, 0.122655154, 0.0845097259]
p_sizes = [p / p_sizes[0] for p in p_sizes]
max_size = 4000
for ss, p_size in zip([6.25, 8.3, 12.5, 25], p_sizes):
for i, _l in enumerate(l):
_l = deepcopy(_l)
per = pl(
{
'netw': {
'size': int(p_size * max_size),
'sub_sampling': {
'M1': ss,
'M2': ss
},
}
}, '=', **{'name': 'ss-' + str(ss)})
_l += per
_l += pl({'simu': {'threads': threads}}, '=')
ll.append(_l)
return ll, threads
def get():
l = []
solution = get_solution()
d = {}
misc.dict_update(d, solution['mul'])
l += [pl(d, '*', **{'name': ''})]
d = {}
misc.dict_update(d, solution['equal'])
dd = {
'conn': {
'GAp_GA_gaba': {
'fan_in': 5
},
'GIp_GA_gaba': {
'fan_in': 25
}
},
'nest': {
'ST_GA_ampa': {
'weight': 0.259
}
}
} #estimate from beta opt
misc.dict_update(d, dd)
l[-1] += pl(d, '=', **{'name': 'control_sim'})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution()
# Decrease/increase C1,C2,CF,CS, EI and EA. Test idea that at
# slow wave cortical and thalamic input is decreased.
mod = numpy.arange(0.5, 1.5, 0.05)
for x in mod:
d = {}
for keys in s_mul:
update(solution, d, keys)
misc.dict_update(d, {'node': {'CF': {'rate': x}}})
misc.dict_update(d, {'node': {'CS': {'rate': x}}})
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
d['node']['C1']['rate'] *= x
d['node']['C2']['rate'] *= x
d['node']['EI']['rate'] *= x
d['node']['EA']['rate'] *= x
l[-1] += pl(d, '=', **{'name': 'mod_C1_C2_CF_CS_EI_EA_' + str(x)})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution_slow_GP_striatum()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
v = STN_ampa_gaba_input_magnitude()
for _, x, y in v:
# x=2.5-1
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
# misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
# misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
# d['node']['EA']['rate']*=0.7
misc.dict_update(d, {'node': {'CS': {'rate': x}}})
misc.dict_update(d, {'nest': {'GI_ST_gaba': {'weight': y}}})
l[-1] += pl(d, '=', **{'name': 'mod_ST_inp_' + str(x) + '_' + str(y)})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
y = 2.5
v = numpy.arange(0.1, 1.2, 0.1)
for x in v:
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
misc.dict_update(d, {'nest': {'ST': {'beta_I_AMPA_1': f_beta_rm(y)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_NMDA_1': f_beta_rm(y)}}})
misc.dict_update(d, {'nest': {'GA_M1_gaba': {'weight': x}}})
misc.dict_update(d, {'nest': {'GA_M2_gaba': {'weight': x}}})
misc.dict_update(d, {'nest': {'GA_FS_gaba': {'weight': x}}})
d['node']['EA']['rate'] *= 0.7
l[-1] += pl(d, '=', **{'name': ('mod_GA_striatum_1' + str(x))})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
v0=numpy.arange(1.25,3.75,0.5)
v1=numpy.arange(2.5, 5.,0.5)
v=[[x,y] for x in v0 for y in v1]
for x, y in v:
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_GABAA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(y)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(y)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':('mod_ST_beta_'
+str(x)+'_'+str(y))
})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for nodes in [['M1', 'M2'],
['M1', 'M2', 'FS'],
['M1', 'M2', 'FS','ST', 'GA', 'GI','SN']]:
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
for node in nodes:
misc.dict_update(d,{'node':{node:{'edge_wrap':False}}})
l[-1]+=pl(d, '=', **{'name':'mod_ST_beta_'+str(x)})
return l
def get():
l = []
solution = get_solution()
d = {}
misc.dict_update(d, solution['mul'])
l += [pl(d, '*', **{'name': ''})]
d = {}
misc.dict_update(d, solution['equal'])
dd = {
'conn': {
'GAp_GA_gaba': {
'fan_in': 5
},
'GIp_GA_gaba': {
'fan_in': 25
}
}
}
misc.dict_update(d, dd)
l[-1] += pl(d, '=', **{'name': 'control_sim'})
return l
def perturbations(rep, res):
threads = 2
l = []
l.append(op.get()[0])
l.append(op3.get()[3])
ll = []
for ss in [25, 50, 75]:
for i, _l in enumerate(l):
_l = deepcopy(_l)
per = pl({'netw': {
'sub_sampling': {
'M1': ss,
'M2': ss
},
}}, '=', **{'name': 'ss-' + str(ss)})
_l += per
_l += pl({'simu': {'threads': threads}}, '=')
ll.append(_l)
return ll, threads
def get():
l = []
solution, s_mul, s_equal = get_solution()
# d0=0.8
# f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
# x=2.5
for x in numpy.arange(0.7, 1.5, 0.2):
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
# misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
# misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate'] *= x
l[-1] += pl(d, '=', **{'name': 'mod_EA_' + str(x)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
# d0=0.8
# f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
# x=2.5
for x in numpy.arange(0.7, 1.5 ,0.2):
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
# misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
# misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=x
l[-1]+=pl(d, '=', **{'name':'mod_EA_'+str(x)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
y=2.5
v=numpy.arange(0.1,1.2,0.1)
for x in v:
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(y)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(y)}}})
misc.dict_update(d,{'nest':{'GA_M1_gaba':{'weight': x}}})
misc.dict_update(d,{'nest':{'GA_M2_gaba':{'weight': x}}})
misc.dict_update(d,{'nest':{'GA_FS_gaba':{'weight': x}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':('mod_GA_striatum_1' + str(x))
})
return l
def get():
l = []
solution = get_solution()
for r in numpy.arange(0, 1200, 200):
r = numpy.float(r)
d = {}
misc.dict_update(d, solution['mul'])
l += [pl(d, '*', **{'name': ''})]
d = {}
misc.dict_update(d, solution['equal'])
dd = {
'conn': {
'GAp_GA_gaba': {
'fan_in': 5
},
'GIp_GA_gaba': {
'fan_in': 25
}
},
'node': {
'EAp': {
'rate': r
}
}
}
misc.dict_update(d, dd)
l[-1] += pl(d, '=', **{'name': 'GAr_{0}'.format(r)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution_slow_GP_striatum()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
v=STN_ampa_gaba_input_magnitude()
for _, x, y in v:
# x=2.5-1
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
# misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
# misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
# d['node']['EA']['rate']*=0.7
misc.dict_update(d,{'node':{'CS':{'rate': x}}})
misc.dict_update(d,{'nest':{'GI_ST_gaba':{'weight':y }}})
l[-1]+=pl(d, '=', **{'name':'mod_ST_inp_'+str(x)+'_'+str(y)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution_slow_GP_striatum()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'mod_ST_beta_'+str(x)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution_slow_GP_striatum()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2.)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'mod_ST_beta_'+str(x)})
return l
def perturbations(rep, res):
threads = 4
l = []
# l.append(op.get()[0])
# l.append(op3.get()[3])
l = op.get()[4::3]
ll = []
p_sizes = [
0.1989460102,
# 0.1608005821,
# 0.122655154,
# 0.0845097259
]
p_sizes = [p / p_sizes[0] for p in p_sizes]
max_size = 4000
for ss, p_size in zip(
[
6.25,
#8.3 ,
#12.5,
# 25
],
p_sizes):
for i, _l in enumerate(l):
_l = deepcopy(_l)
per = pl(
{
'netw': {
'size': int(p_size * max_size),
'sub_sampling': {
'M1': ss,
'M2': ss
},
}
}, '=', **{'name': 'ss-' + str(ss)})
_l += per
_l += pl({'simu': {'threads': threads}}, '=')
ll.append(_l)
for _l in ll:
_l += pl(
{
'conn': {
'FS_M1_gaba': {
'rule': 'set-not_set'
},
'FS_M2_gaba': {
'rule': 'set-not_set'
}
}
}, '=')
return ll, threads
def get():
def get_perturbation_dics(c, w_rel):
d = {}
for key in c.keys():
for conn in c[key]:
u = {key: {'nest': {conn: {'weight': w_rel}}}}
d = misc.dict_update(d, u)
return d
c = {
'FS_FS': ['FS_FS_gaba'],
'FS_MS': ['FS_M1_gaba', 'FS_M2_gaba'],
'FS_M1': ['FS_M1_gaba'],
'FS_M2': ['FS_M2_gaba'],
'GA_FS': ['GA_FS_gaba'],
'GA_GA': ['GA_GA_gaba'],
'GA_GI': ['GA_GI_gaba'],
'GA_M1': ['GA_M1_gaba'],
'GA_M2': ['GA_M2_gaba'],
'GI_GA': ['GI_GA_gaba'],
'GI_GI': ['GI_GI_gaba'],
'GI_SN': ['GI_SN_gaba'],
'GI_ST': ['GI_ST_gaba'],
'M1_SN': ['M1_SN_gaba'],
'M2_GI': ['M2_GI_gaba'],
'MS_MS': ['M1_M1_gaba', 'M1_M2_gaba', 'M2_M1_gaba', 'M2_M2_gaba'],
'M1_M1': ['M1_M1_gaba'],
'M1_M2': ['M1_M2_gaba'],
'M2_M1': ['M2_M1_gaba'],
'M2_M2': ['M2_M2_gaba'],
'ST_GA': ['ST_GA_ampa'],
'ST_GI': ['ST_GI_ampa'],
'ST_SN': ['ST_SN_ampa'],
}
mod = [
0.06125,
0.125,
0.25,
0.5,
0.75, # 0.75,
1.33,
2,
4,
8,
16
]
l = []
l += [pl(**{'name': 'no_pert'})]
for key, val in c.items():
for w_rel in mod:
d = get_perturbation_dics({key: val}, w_rel)
l.append(
pl(d.values()[0], '*',
**{'name': d.keys()[0] + '_pert_' + str(w_rel)}))
return l
def pert_add_go_nogo_ss(**kwargs):
l = kwargs.get('perturbation_list')
do_not_record = kwargs.get('do_not_record', [])
local_num_threads = kwargs.get('local_num_threads')
max_size = kwargs.get('max_size')
p_sizes = kwargs.get('p_sizes')
p_subsamp = kwargs.get('p_subsamp')
to_memory = kwargs.get('to_memory', False)
to_file = kwargs.get('to_file', True)
ll = []
p_sizes = [p / max(p_sizes) for p in p_sizes]
for ss, p_size in zip(p_subsamp, p_sizes):
for i, _l in enumerate(l):
_l = deepcopy(_l)
per = pl(
{
'netw': {
'size': int(p_size * max_size),
'sub_sampling': {
'M1': ss,
'M2': ss
},
}
}, '=', **{'name': 'ss-' + str(ss)})
_l += per
_l += pl(
{
'simu': {
'local_num_threads': local_num_threads,
'do_reset': True,
'sd_params': {
'to_file': to_file,
'to_memory': to_memory
}
}
}, '=')
if do_not_record:
for model in do_not_record:
_l += pl(
{'node': {
model: {
'sd': {
'active': False
}
}
}},
'=',
# **{'name':'exclude-'+'_'.join(do_not_record)}
)
ll.append(_l)
return ll
def perturbations(rep, res):
threads = 20
l = []
# l.append(op.get()[0])
# l.append(op.get()[4::3])
l.append(op.get()[4 + 3])
ll = []
# w=0.4
p_sizes = [0.1989460102, 0.1608005821, 0.122655154, 0.0845097259]
p_sizes = [p / p_sizes[0] for p in p_sizes]
max_size = 4000
for ss, p_size in zip([6.25, 8.3, 12.5, 25], p_sizes):
for i, _l in enumerate(l):
_l = deepcopy(_l)
per = pl(
{
'netw': {
'size': int(p_size * max_size),
'sub_sampling': {
'M1': ss,
'M2': ss
},
}
}, '=', **{'name': 'ss-' + str(ss)})
_l += per
_l += pl({'simu': {'threads': threads}}, '=')
ll.append(_l)
# for _l in deepcopy([ll[0]]):
# _lr=deepcopy(_l)
# _lr.update_list(
# pl({'nest':{'GA_M1_gaba':{'weight':5*2.*w},
# # 'GA_FS_gaba':{'weight':0.1}
# }},'*', **{'name':'GA-XX-equal'}))
# ll.append(_lr)
#
# _lr=deepcopy(_l)
# _lr.update_list(
# pl({'nest':{'GA_M1_gaba':{'weight':5*4.*w},
# # 'GA_FS_gaba':{'weight':0.1}
# }},'*', **{'name':'GA-XX-equal'}))
# ll.append(_lr)
#
# _lr=deepcopy(_l)
# _lr.update_list(
# pl({'nest':{'GA_M1_gaba':{'weight':5*0.5*w},
# # 'GA_FS_gaba':{'weight':0.1}
# }},'*', **{'name':'GA-XX-equal'}))
# ll.append(_lr)
return ll, threads
def get():
l = []
solution, s_mul, s_equal = get_solution()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
# v=STN_ampa_gaba_input_magnitude()[0:5]
for _, u, w in v:
v0 = numpy.arange(1.25, 3.75, 1.)
v1 = numpy.arange(1.5, 4, 1.)
v = [[x, y] for x in v0 for y in v1]
for x, y in v:
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
misc.dict_update(
d, {'nest': {
'ST': {
'beta_I_GABAA_1': f_beta_rm(x)
}
}})
misc.dict_update(d,
{'nest': {
'ST': {
'beta_I_AMPA_1': f_beta_rm(y)
}
}})
misc.dict_update(d,
{'nest': {
'ST': {
'beta_I_NMDA_1': f_beta_rm(y)
}
}})
misc.dict_update(d, {'node': {'CS': {'rate': u}}})
misc.dict_update(d, {'nest': {'GI_ST_gaba': {'weight': w}}})
d['node']['EA']['rate'] *= 0.7
l[-1] += pl(
d, '=', **{
'name': ('mod_ST_beta_' + str(u) + '_' + str(w) + '_' +
str(x) + '_' + str(y))
})
return l
def get():
l = []
solution = get_solution_slow_GP_striatum_2()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
for y, x in zip(numpy.arange(5., 29., 5.), [1., 1.1, 1.15, 1.2, 1.25]):
z = 1.25
d = {}
misc.dict_update(d, solution['mul'])
misc.dict_update(d, {'node': {'CS': {'rate': z}}})
misc.dict_update(d, {'node': {'CF': {'rate': x}}})
l += [pl(d, '*', **{'name': ''})]
d = {}
misc.dict_update(d, solution['equal'])
dd = {
'conn': {
'GA_GA_gaba': {
'fan_in0': y,
'rule': 'all-all'
},
'GA_GI_gaba': {
'fan_in0': 2,
'rule': 'all-all'
},
'GI_GA_gaba': {
'fan_in0': 30 - y,
'rule': 'all-all'
},
'GI_GI_gaba': {
'fan_in0': 28,
'rule': 'all-all'
}
}
}
misc.dict_update(d, dd)
d['node']['EI']['rate'] *= z
d['node']['EA']['rate'] = 200.0
misc.dict_update(d, {'nest': {'GI': {'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1] += pl(d, '=',
**{'name': 'GAGA_' + str(y) + '_GIGA_' + str(30 - y)})
return l
def perturbations():
sim_time = 10000.0
size = 20000.0
threads = 1
freqs = [1., 2.0]
path = ('/home/mikael/results/papers/inhibition' +
'/network/simulate_inhibition_ZZZ4/')
l = op.get()[-3:]
for i in range(len(l)):
l[i] += pl(
{
'simu': {
'sim_time': sim_time,
'sim_stop': sim_time,
'threads': threads
},
'netw': {
'size': size
}
}, '=')
damp = process(path, freqs)
for key in sorted(damp.keys()):
val = damp[key]
print numpy.round(val, 2), key
ll = []
for i, _l in enumerate(l):
for j, _ in enumerate(freqs):
amp = [numpy.round(damp[_l.name][j], 2), 1]
d = {
'type': 'oscillation2',
'params': {
'p_amplitude_mod': amp[0],
'p_amplitude0': amp[1],
'freq': 20.
}
}
_ll = deepcopy(_l)
dd = {}
for key in ['C1', 'C2', 'CF', 'CS']:
dd = misc.dict_update(dd, {'netw': {'input': {key: d}}})
_ll += pl(dd, '=', **{'name': 'amp_{0}-{1}'.format(*amp)})
ll.append(_ll)
return ll, threads
def get():
l = []
solution = get_solution()
rEI = 1700.0
rEA = 200.0
rCS = 250.0
rES = 1800.0
rM2 = 740.0
d = {}
misc.dict_update(d, solution['mul'])
l += [pl(d, '*', **{'name': ''})]
d = {}
misc.dict_update(d, solution['equal'])
d['node']['EI']['rate'] = rEI
d['node']['EA']['rate'] = rEA
d['node']['C2']['rate'] = rM2
misc.dict_update(d, {'node': {'CS': {'rate': rCS}}})
misc.dict_update(d, {'node': {'ES': {'rate': rES}}})
s = 'rEI_{0}_rEA_{1}_rCS_{2}_rES_{3}_rM2_{4}'.format(
rEI, rEA, rCS, rES, rM2)
l[-1] += pl(d, '=', **{'name': s})
rEI = 800.0
rEA = 100.0
rCS = 170.0
rES = 1800.0
rM2 = 740.0
d = {}
misc.dict_update(d, solution['mul'])
l += [pl(d, '*', **{'name': ''})]
d = {}
misc.dict_update(d, solution['equal'])
d['node']['EI']['rate'] = rEI
d['node']['EA']['rate'] = rEA
d['node']['C2']['rate'] = rM2
misc.dict_update(d, {'node': {'CS': {'rate': rCS}}})
misc.dict_update(d, {'node': {'ES': {'rate': rES}}})
s = 'rEI_{0}_rEA_{1}_rCS_{2}_rES_{3}_rM2_{4}'.format(
rEI, rEA, rCS, rES, rM2)
l[-1] += pl(d, '=', **{'name': s})
return l
def get():
l = []
solution, s_mul, s_equal = get_solution()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
# betas MS-MS
v = [0.1, 0.25, 0.5, 0.75]
for x, y in [[v1, v2] for v1 in v for v2 in v]:
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
misc.dict_update(d,
{'nest': {
'ST': {
'beta_I_AMPA_1': f_beta_rm(2.5)
}
}})
misc.dict_update(d,
{'nest': {
'ST': {
'beta_I_NMDA_1': f_beta_rm(2.5)
}
}})
d['node']['EA']['rate'] *= 0.7
misc.dict_update(d, {'nest': {'MS': {'beta_I_GABAA_2': f_beta_rm(x)}}})
for conn in ['M1_M1_gaba', 'M1_M2_gaba', 'M2_M1_gaba', 'M2_M2_gaba']:
misc.dict_update(d,
{'conn': {
conn: {
'beta_fan_in': f_beta_rm(y)
}
}})
l[-1] += pl(d, '=', **{'name': 'mod_MSg_' + str(x) + '_MSc_' + str(y)})
#beta CTX-STN
return l
def get():
l=[]
solution=get_solution_slow_GP_striatum_2()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for y in [1.1, 1.2, 1.3]:
d={}
misc.dict_update(d, solution['mul'])
misc.dict_update(d,{'node':{'CS':{'rate': y}}})
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
d['node']['EI']['rate']*=y*0.9
d['node']['EA']['rate']*=y
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'all_CSEIEA_'+str(y)})
y=1.2
d={}
misc.dict_update(d, solution['mul'])
misc.dict_update(d,{'node':{'CS':{'rate': y}}})
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
d['node']['EI']['rate']*=y*0.9
d['node']['EA']['rate']*=0.0
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'all_CSEIEA_'+str(y)})
return l
def setUp(self):
from core.network.default_params import Perturbation_list as pl
from_disk=2
import oscillation_perturbations4 as op
rep=2
sim_time=rep*1000.0
local_num_threads=20
l=op.get()
p=pl({'simu':{'sim_time':sim_time,
'sim_stop':sim_time,
'local_num_threads':local_num_threads}},
'=')
p+=l[7]
self.setup=Setup(**{'local_num_threads':local_num_threads,
'repetition':rep})
v=simulate(builder=Builder,
from_disk=from_disk,
perturbation_list=p,
script_name=(__file__.split('/')[-1][0:-3]
+'/data'),
setup=self.setup)
file_name, file_name_figs, from_disks, d, models= v
self.file_name_figs=file_name_figs
self.from_disks=from_disks
self.d=d
self.models=models
def test_do(self):
d={'simu':{'sim_stop':20000.0,
'sim_time':20000.0,
'stop_rec':20000.0,
'start_rec':1000.0}}
per=pl(d, '=')
per+=op.get()[0]
kw_setup={'nets_to_run':['Net_1'],
# 'single_unit':'GA',
# 'opt':{'Net_1':{'f':['GA'],
# 'x':['nest.ST_GA_ampa.weight'],
# 'x0':[0.45]}},
'single_unit':'GI',
'opt':{'Net_1':{'f':['GI'],
'x':['node.EIp.rate'],
'x0':[1000.0]}},
'tp_name':'beta'}
kwargs={'builder':builder,
'perturbation_list':per,
'script_name':__file__.split('/')[-1][0:-3],
'setup':Setup(**kw_setup)
}
obj=Main(**kwargs)
obj.do()
def pert_add_single(**kwargs):
do_reset = kwargs.get('do_reset', True)
local_num_threads = kwargs.get('local_num_threads')
perturbation_list = kwargs.get('perturbation_list')
sim_time = kwargs.get('sim_time')
size = kwargs.get('size')
l = perturbation_list
for i in range(len(l)):
l[i] += pl(
{
'simu': {
'do_reset': do_reset,
'sd_params': {
'to_file': True,
'to_memory': False
},
'sim_time': sim_time,
'sim_stop': sim_time,
'stop_rec': sim_time,
'local_num_threads': local_num_threads
},
'netw': {
'size': size
}
}, '=')
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution_slow_GP_striatum()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
x=2.5
d={}
for y in [12]+ list(numpy.arange(5,55,5)):
# x=3.4
# y=2.25
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
ratio=12./y
dd={'nest':{'GA_M1_gaba':{'weight':0.8*ratio},
'GA_M2_gaba':{'weight':0.8*ratio}}}
misc.dict_update(d,dd)
# Decreasing from 2 leads to ...
# Increasing from 2 leads to ...
dd={'nest':{'GA_FS_gaba':{'weight':2.*ratio}}}
misc.dict_update(d,dd)
# Just assumed to be 12 ms
dd={'nest':{'M1_low':{'GABAA_3_Tau_decay':12./ratio},
'M2_low':{'GABAA_3_Tau_decay':12./ratio},
'FS_low':{'GABAA_2_Tau_decay':12./ratio},
}}
misc.dict_update(d,dd)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'mod_GAtau_'+str(y)})
return l
def get():
l=[]
d={}
for name in ['M1', 'CTX_M1', 'CTX_M2', 'MS_MS', 'FS_FS',
'GP_FS', 'FS_M2', 'M2_GI', 'FS',
'GA_MS', 'GA_FS', 'GI_FS']:
d=misc.dict_update(d, get_change_to(name))
l+=[pl(d,'*', **{'name':'no_ch_dop-striatum'})]
d={}
for name in ['CTX_ST', 'GP_ST', 'GP', 'ST_GP', 'GP_GP', 'SN', 'M1_SN']:
d=misc.dict_update(d, get_change_to(name))
l+=[pl(d,'*', **{'name':'no_ch_dop-GP_ST_SN'})]
d={}
for name in ['M1', 'CTX_M1', 'CTX_M2', 'MS_MS', 'FS_FS',
'GP_FS', 'FS_M2', 'CTX_ST', 'GP_ST', 'GP',
'ST_GP', 'GP_GP', 'SN', 'M1_SN',
'M2_GI', 'FS',
'GA_MS', 'GA_FS', 'GI_FS']:
d=misc.dict_update(d, get_change_to(name))
pp(d)
l+=[pl(d,'*', **{'name':'no_ch_dop-all'})]
for s in [ 'CTX_M1', 'CTX_M2', 'MS_MS', 'FS_FS',
'GP_FS', 'FS_M2', 'CTX_ST', 'GP_ST', 'GP',
'ST_GP', 'GP_GP', 'SN', 'M1_SN', 'M2_GI',
'FS','M1',
'GA_MS', 'GA_FS', 'GI_FS']:
d={}
for name in [s]:
d=misc.dict_update(d, get_change_to(name))
l+=[pl(d,'*', **{'name':'no_ch-'+s})]
d={}
l+=[pl(d,'*', **{'name':'-Normal'})]
return l
def get():
l = []
solution, s_mul, s_equal = get_solution()
d0 = 0.8
f_beta_rm = lambda f: (1 - f) / (d0 + f * (1 - d0))
y = 2.5
w = numpy.arange(0.5, 1.2, 0.1)
v = [0.1, 0.25, 0.5]
ll = [[v1, v2] for v1 in v for v2 in w]
pp(l)
for x, z in ll:
print x, z
d = {}
for keys in s_mul:
update(solution, d, keys)
l += [pl(d, '*', **{'name': ''})]
d = {}
for keys in s_equal:
update(solution, d, keys)
misc.dict_update(d, {'nest': {'ST': {'beta_I_AMPA_1': f_beta_rm(y)}}})
misc.dict_update(d, {'nest': {'ST': {'beta_I_NMDA_1': f_beta_rm(y)}}})
misc.dict_update(d, {'nest': {'MS': {'beta_I_GABAA_2': f_beta_rm(x)}}})
for conn in ['M1_M1_gaba', 'M1_M2_gaba', 'M2_M1_gaba', 'M2_M2_gaba']:
misc.dict_update(d,
{'conn': {
conn: {
'beta_fan_in': f_beta_rm(x)
}
}})
misc.dict_update(d, {'nest': {'GA_M1_gaba': {'weight': z}}})
misc.dict_update(d, {'nest': {'GA_M2_gaba': {'weight': z}}})
misc.dict_update(d, {'nest': {'GA_FS_gaba': {'weight': z}}})
d['node']['EA']['rate'] *= 0.7
l[-1] += pl(d, '=',
**{'name': ('mod_GA_str_' + str(z) + '_MS_' + str(x))})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution_slow_GP_striatum_2()
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
l[-1]+=pl(d, '=', **{'name':''})
return l
def get():
l=[]
solution=get_solution_slow_GP_striatum_2()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for z in [1.05,1.1]:
for a,b in zip([900., 1200.0 ],
[a*0.25 for a in [0.75, 0.5]]):
for y in numpy.arange(5.,29.,5.):
# z=0.8
d={}
misc.dict_update(d, solution['mul'])
misc.dict_update(d,{'node':{'CS':{'rate': z}}})
misc.dict_update(d,{'nest':{'ST_GA_ampa':{'weight':b}}})
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
dd={'conn': {'GA_GA_gaba':{'fan_in0': y,'rule':'all-all' },
'GA_GI_gaba':{'fan_in0': 2,'rule':'all-all' },
'GI_GA_gaba':{'fan_in0': 30-y,'rule':'all-all' },
'GI_GI_gaba':{'fan_in0': 28,'rule':'all-all' }}}
misc.dict_update(d, dd)
d['node']['EI']['rate']*=z
d['node']['EA']['rate']=a
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'exc'+str(z)
+'_EIEACS_'+str(a)
+'_STGAw_'+str(b)
+'_GAGA_'+str(y)
+'_GIGA_'+str(30-y)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
y=2.5
w=numpy.arange(0.5, 1.2, 0.1)
v=[0.1,0.25, 0.5]
ll=[[v1,v2] for v1 in v for v2 in w]
pp(l)
for x, z in ll:
print x,z
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(y)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(y)}}})
misc.dict_update(d,{'nest':{'MS':{'beta_I_GABAA_2': f_beta_rm(x)}}})
for conn in ['M1_M1_gaba', 'M1_M2_gaba','M2_M1_gaba','M2_M2_gaba']:
misc.dict_update(d,{'conn':{conn:{'beta_fan_in': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'GA_M1_gaba':{'weight': z}}})
misc.dict_update(d,{'nest':{'GA_M2_gaba':{'weight': z}}})
misc.dict_update(d,{'nest':{'GA_FS_gaba':{'weight': z}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':('mod_GA_str_' + str(z)+'_MS_'+str(x))
})
return l
def get():
l=[]
solution=get_solution_slow_GP_striatum_2()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for a,b in zip([200., 300., 300., 400., 500.],
[a*0.25 for a in [0.75, 0.75, 0.5, 0.5, 0.5]]):
z=1.2
y=0.75
d={}
misc.dict_update(d, solution['mul'])
misc.dict_update(d,{'node':{'CS':{'rate': y}}})
misc.dict_update(d,{'node':{'CF':{'rate': z}}})
misc.dict_update(d,{'nest':{'ST_GA_ampa':{'weight':b}}})
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
d['node']['EI']['rate']*=y
d['node']['EA']['rate']=a
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'all_EIEACS_'+str(a)+'_STGAw_'+str(b)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
# v=STN_ampa_gaba_input_magnitude()[0:5]
for _, u, w in v:
v0=numpy.arange(1.25, 3.75, 1.)
v1=numpy.arange(1.5, 4, 1.)
v=[[x,y] for x in v0 for y in v1]
for x, y in v:
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_GABAA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(y)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(y)}}})
misc.dict_update(d,{'node':{'CS':{'rate': u}}})
misc.dict_update(d,{'nest':{'GI_ST_gaba':{'weight':w }}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':('mod_ST_beta_'
+str(u)+'_'+str(w)+'_'
+str(x)+'_'+str(y))
})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
# betas MS-MS
v=numpy.arange(1.5,3,0.25)
for x in v:
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
l[-1]+=pl(d, '=', **{'name':'mod_ST_beta_'+str(x)})
v1=numpy.arange(0.1, 1, 0.2)
for x in v1:
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
d['node']['EA']['rate']*=x
l[-1]+=pl(d, '=', **{'name':'mod_EA_'+str(x)})
v2=numpy.arange(1.1, 2, 0.2)
for x in v2:
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
d['node']['EI']['rate']*=x
l[-1]+=pl(d, '=', **{'name':'mod_EI_'+str(x)})
return l
def get():
l=[]
solution=get_solution_slow_GP_striatum_2()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for y,x in zip(numpy.arange(5.,29.,5.), [1., 1.1, 1.15, 1.2, 1.25]):
z=0.8
d={}
misc.dict_update(d, solution['mul'])
misc.dict_update(d,{'node':{'CS':{'rate': z}}})
misc.dict_update(d,{'node':{'CF':{'rate': x}}})
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
dd={'conn': {'GA_GA_gaba':{'fan_in0': y,'rule':'all-all' },
'GA_GI_gaba':{'fan_in0': 2,'rule':'all-all' },
'GI_GA_gaba':{'fan_in0': 30-y,'rule':'all-all' },
'GI_GI_gaba':{'fan_in0': 28,'rule':'all-all' }}}
misc.dict_update(d, dd)
d['node']['EI']['rate']*=z
d['node']['EA']['rate']=200.0
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'GAGA_'+str(y)+'_GIGA_'+str(30-y)})
return l
def get():
l=[]
for y in [0.8, 1.2]:
w=0.75
l+=[pl({'nest':{'GA_M1_gaba':{'weight':y},
'GA_M2_gaba':{'weight':y},
'M1_M1_gaba':{'weight':0.25},
'M1_M2_gaba':{'weight':0.25},
'M2_M1_gaba':{'weight':0.25},
'M2_M2_gaba':{'weight':0.25},
'ST_GA_ampa':{'weight':0.25},
'GA_GA_gaba':{'weight':0.25},
'GI_GA_gaba':{'weight':0.25},
'GI_ST_gaba':{'weight':w},
'ST_GI_ampa':{'weight':w}
}},
'*',
**{'name':'MsGa-MS-weight0.25_ST-GI-'+str(w)
+ '-GaMs-'+str(y)})]
l[-1]+=pl({
'node':{'C1':{'rate':560.0},
'C2':{'rate':700.},
'EI':{'rate':1060.0},
'EA':{'rate':330.0}}},
'=',
**{'name':'down-C2-EiEa-mod'})
for y in [0.8, 1.2]:
x=5.
w=0.75
l+=[pl({'nest':{'M1_M1_gaba':{'weight':0.25},
'M1_M2_gaba':{'weight':0.25},
'M2_M1_gaba':{'weight':0.25},
'M2_M2_gaba':{'weight':0.25},
'ST_GA_ampa':{'weight':0.25},
'GA_GA_gaba':{'weight':0.25},
'GI_GA_gaba':{'weight':0.25},
'GI_ST_gaba':{'weight':w},
'ST_GI_ampa':{'weight':w}
}},
'*',
**{'name':'MsGa-MS-weight0.25_ST-GI-'+str(w)
+ '-GaMs-'+str(y)})]
l[-1]+=pl({
'node':{'C1':{'rate':560.0},
'C2':{'rate':700.},
'EI':{'rate':1060.0},
'EA':{'rate':330.0}}},
'=',
**{'name':'down-C2-EiEa-mod'})
l[-1]+=pl({'nest':{'GA_M1_gaba':{'weight':y*x},
'GA_M2_gaba':{'weight':y*x},
'GA_FS_gaba':{'weight':x},
'M1_low':{'GABAA_3_Tau_decay':1./5},
'M2_low':{'GABAA_3_Tau_decay':1./5},
'FS_low':{'GABAA_2_Tau_decay':1./5},
}},
'*',
**{'name':'fast-'+str(x)})
for y in [0.4, 0.5, 0.6]:
w=0.75
l+=[pl({'nest':{'GA_M1_gaba':{'weight':y},
'GA_M2_gaba':{'weight':y},
'M1_M1_gaba':{'weight':0.25},
'M1_M2_gaba':{'weight':0.25},
'M2_M1_gaba':{'weight':0.25},
'M2_M2_gaba':{'weight':0.25},
'ST_GA_ampa':{'weight':0.25},
'GA_GA_gaba':{'weight':0.25},
'GI_GA_gaba':{'weight':0.25},
'GI_ST_gaba':{'weight':w},
'ST_GI_ampa':{'weight':w}
}},
'*',
**{'name':'MsGa-MS-weight0.25_ST-GI-'+str(w)
+ '-GaMs-'+str(y)})]
l[-1]+=pl({
'node':{'C1':{'rate':560.0},
'C2':{'rate':700.},
'EI':{'rate':1060.0},
'EA':{'rate':330.0}}},
'=',
**{'name':'down-C2-EiEa-mod'})
for y in [0.4, 0.5, 0.6]:
x=5.
w=0.75
l+=[pl({'nest':{'M1_M1_gaba':{'weight':0.25},
'M1_M2_gaba':{'weight':0.25},
'M2_M1_gaba':{'weight':0.25},
'M2_M2_gaba':{'weight':0.25},
'ST_GA_ampa':{'weight':0.25},
'GA_GA_gaba':{'weight':0.25},
'GI_GA_gaba':{'weight':0.25},
'GI_ST_gaba':{'weight':w},
'ST_GI_ampa':{'weight':w}
}},
'*',
**{'name':'MsGa-MS-weight0.25_ST-GI-'+str(w)
+ '-GaMs-'+str(y)})]
l[-1]+=pl({
'node':{'C1':{'rate':560.0},
'C2':{'rate':700.},
'EI':{'rate':1060.0},
'EA':{'rate':330.0}}},
'=',
**{'name':'down-C2-EiEa-mod'})
l[-1]+=pl({'nest':{'GA_M1_gaba':{'weight':y*x},
'GA_M2_gaba':{'weight':y*x},
'GA_FS_gaba':{'weight':x},
'M1_low':{'GABAA_3_Tau_decay':1./5},
'M2_low':{'GABAA_3_Tau_decay':1./5},
'FS_low':{'GABAA_2_Tau_decay':1./5},
}},
'*',
**{'name':'fast-'+str(x)})
return l
def get():
l=[]
solution, s_mul, s_equal=get_solution_slow_GP_striatum()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for y in numpy.arange(1.0,-0.1,-0.5):
for z in numpy.arange(1.0,-0.1,-0.5):
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
misc.dict_update(d,{'nest':{'GI_GA_gaba':{'weight':y}}})
misc.dict_update(d,{'nest':{'ST_GA_ampa':{'weight':z}}})
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'GIGA_'+str(y)+'_STGA_'+str(z)})
for y in numpy.arange(1.,6.):
for z in numpy.arange(1.,6.):
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'ST_GA_ampa':{'delay':y}}})
misc.dict_update(d,{'nest':{'ST_GI_ampa':{'delay':y}}})
misc.dict_update(d,{'nest':{'GI_ST_gaba':{'delay':z}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'STGPdelay_'+str(y)+'_GPSTdelay_'+str(z)})
for y in numpy.arange(2.5, 21., 2.5):
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'CS_ST_ampa':{'delay':y}}})
misc.dict_update(d,{'nest':{'CS_ST_nmda':{'delay':y}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'CSSTdelay_'+str(y)})
for y in numpy.arange(2.5, 21., 2.5):
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'C1_M1_ampa':{'delay':y}}})
misc.dict_update(d,{'nest':{'C1_M1_nmda':{'delay':y}}})
misc.dict_update(d,{'nest':{'C2_M2_ampa':{'delay':y}}})
misc.dict_update(d,{'nest':{'C2_M2_nmda':{'delay':y}}})
misc.dict_update(d,{'nest':{'CF_FS_ampa':{'delay':y}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_AMPA_1': f_beta_rm(x)}}})
misc.dict_update(d,{'nest':{'ST':{'beta_I_NMDA_1': f_beta_rm(x)}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'CSTRdelay_'+str(y)})
for y in numpy.arange(1, 8., 1.):
x=2.5
d={}
for keys in s_mul: update(solution, d, keys)
l+=[pl(d, '*', **{'name':''})]
d={}
for keys in s_equal: update(solution, d, keys)
misc.dict_update(d,{'nest':{'GA_M1_gaba':{'delay':y}}})
misc.dict_update(d,{'nest':{'GA_M2_gaba':{'delay':y}}})
misc.dict_update(d,{'nest':{'GA_FS_gaba':{'delay':y}}})
d['node']['EA']['rate']*=0.7
l[-1]+=pl(d, '=', **{'name':'GASTRdelay_'+str(y)})
return l
2 (51) GA_M2_pert_0.0 OOM
5 (137) GA_FS_pert_5 time
7 (161) ST_GA_pert_0.0 OOM
8 (171) ST_GA_pert_5 time
10 (187) GI_GA_pert_0.0 ?
11 (201) M2_GI_pert_0.0 OOM
12 (211) M2_GI_pert_5 OOM
15 (16) M1_pert_mod7 OOM
18 (40) M2_pert_mod7 Mem python
19 (49) GI_pert_mod0 OOM
20 (56) GI_pert_mod7 ?
21 (57) ST_pert_mod0 OOM
22 (64) ST_pert_mod7 ?
'''
op_pert_add=[pl(**{'name':'Control'})]
opc=op_conn.get([0,6])
op_pert_add+=[opc[i] for i in l_op_conn]
opn=op_nuc.get([0,7])
op_pert_add+=[opn[i] for i in l_op_nuc]
opn=op_dop.get()
op_pert_add+=[opn[i] for i in l_op_dop]
opc=op_conn.get([0,6])
op_pert_add+=[opc[i] for i in l_op_conn2]
def main(*args, **kwargs):
setup=kwargs.get('setup')#, Setup())
script_name=kwargs.get('script_name')#,__file__.split('/')[-1][0:-3])
builder=kwargs.get('builder')
info, nets, _ = get_networks(builder,
setup.builder(),
setup.director(),
setup.engine(),
setup.default_params())
perturbation_list=kwargs.get('perturbation_list')
perturbation_list+=pl(target_perturbations()[setup.tp_name], '=', **{'name':setup.tp_name})
perturbation_list+=pl(setup.par(), '=', **{'name':setup.tp_name})
add_perturbations(perturbation_list, nets)
key=nets.keys()[0]
file_name = get_file_name(script_name, nets[key].par)
path_nest=get_path_nest(script_name, nets.keys(), nets[key].par)
for val in nets.values():
for key in sorted(val.par['nest'].keys()):
val2=val.par['nest'][key]
if 'weight' in val2.keys():
print key, val2['weight']
for key in sorted(val.par['node'].keys()):
val2=val.par['node'][key]
if 'spike_setup' in val2.keys():
print key, val2['spike_setup']
if 'rate' in val2.keys():
print key, val2['rate']
print setup.tp_name, nets.keys()
pp(nets['Net_1'].par['nest']['GA_GA_gaba']['weight'])
for net in nets.values():
net.set_path_nest(path_nest)
pp(nets['Net_1'].par['nest']['GA_GA_gaba']['weight'])
net.set_opt(setup.opt[net.name])
pp(nets['Net_1'].par['nest']['GA_GA_gaba']['weight'])
# vt=net.voltage_trace()
# import pylab
# ax=pylab.subplot(111)
# vt.plot_voltage_trace(ax)
# pylab.show()
sd_list=get_storage_list(nets.keys(), file_name, info)
for net, sd in zip(nets.values(), sd_list):
nl=Network_list([net])
# pp(net.par.dic['node']['STp'])
kwargs={'model':nl,
'call_get_x0':'get_x0',
'call_get_error':'sim_optimization',
'verbose':True,}
kwargs_fmin={'maxiter':100,
'maxfun':100,
'full_output':1,
'retall':1,
'xtol':.0001,
'ftol':.0001,
'disp':0}
kwargs_fmin={}
kwargs['kwargs_fmin']=kwargs_fmin
f=Fmin('GA_opt', **kwargs)
h=f.fmin()
dd={setup.tp_name.split('_')[0]:{net.name:{'opt':h}}}
save(sd, dd)
def get(index=[]):
def get_perturbation_dics(val, hz_mod, i):
d = {}
# for key in c.keys():
for neuron, hz_pA in val:
hz=hz_mod[neuron][i]
u = {key:{'node':{neuron:{'I_vivo':1./hz_pA*hz}}}}
d = misc.dict_update(d, u)
return d
c={
'M1':[['M1',0.16]], #5/32 Hz/pA
'M2':[['M2',0.13]], #5/40 Hz/pA
'FS':[['FS',0.17]], #10/60 Hz/pA
'GP':[['GA',0.47],
['GI',0.47]], #0.47 Hz/pA
'GA':[['GA',0.47]], #0.47 Hz/pA
'GI':[['GI',0.47],
['GF',0.47]], #0.47 Hz/pA
'ST':[['ST',0.54]], #0.54 Hz/pA
'SN':[['SN',0.16]]} #0.16 Hz/pA
#in hz
f=2
mod={'M1':[a*2 for a in [-8, -6,-4,-2, #
2, 4, 6, 8]],
'M2':[a*2 for a in [-8, -6,-4,-2, #
2, 4, 6, 8]],
'FS':[a*1.1 for a in [-20, -15,-10,-5, #
5, 10, 15, 20 ]],
'GA':[1.5*a for a in [-20, -15,-10,-5, #
f*5, f*10, f*15, f*20 ]],
'GI':[a*4 for a in [-60, -45,-30,-15, #
f*15, f*30, f*45, f*60]],
'GF':[a*4 for a in [-60, -45,-30,-15, #
f*15, f*30, f*45, f*60]],
'ST':[a*2 for a in [-30, -22.5,-15,-7.5, #
f*7.5, f*15, f*22.5, f*30 ]],
'SN':[a*4 for a in [-40, -30,-20,-10, #
10, 20, 30, 40]]}
if index:
for key, val in mod.items():
mod[key]=[v for i,v in enumerate(val) if i in index]
l=[]
n=len(mod['M1'])
l+=[pl(**{'name':'no_pert'})]
for key, val in c.items():
for i in range(n):
d=get_perturbation_dics(val, mod, i)
l.append(pl(d.values()[0],'+', **{'name':(key
+'_pert_mod'
+str(int(i)))}))
# neuron, hz_pA=val
# for neuron, mods in mod.items():
# for hz in mods:
# d=get_perturbation_dics({key:val}, mod, i)
# d={key:{'node':{neuron:{'I_vivo':1./hz_pA*hz}}}}
#
# l.append(pl(d.values()[0],'+', **{'name':(d.keys()[0]
# +'_pert_mod'
# +str(int(hz*hz_pA)))}))
#
return l
def get():
l=[]
solution=get_solution_slow_GP_striatum_2()
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for y in [1.2, 1.3]:
d={}
misc.dict_update(d, solution['mul'])
misc.dict_update(d,{'node':{'CS':{'rate': y}}})
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
dd={'conn': {'GA_GA_gaba':{'fan_in0': 20,'rule':'all-all' },
'GA_GI_gaba':{'fan_in0': 2,' rule':'all-all' },
'GI_GA_gaba':{'fan_in0': 10,'rule':'all-all' },
'GI_GI_gaba':{'fan_in0': 28,'rule':'all-all' }}}
misc.dict_update(d, dd)
misc.dict_update(d,{'conn':{'GI_FS_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_FS_gaba':{'fan_in0': 2}}})
misc.dict_update(d,{'conn':{'GI_M1_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_M1_gaba':{'fan_in0': 2}}})
misc.dict_update(d,{'conn':{'GI_M2_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_M2_gaba':{'fan_in0': 2}}})
# d['node']['EA']['rate']*=0.9
# misc.dict_update(d,{'conn':{'M2_GA_gaba':{'lesion': False}}})
# misc.dict_update(d,{'conn':{'M2_GA_gaba':{'fan_in0': 25}}})
d['node']['EI']['rate']*=y*0.9
d['node']['EA']['rate']*=y
# d['node']['CS']['rate']*=y
#
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'all_EIEA_'+str(y)})
for a,b in zip([1.1, 1.2, 1.7, 2.3, 2.5],
[a*0.25 for a in [0.75, 0.5, 0.25, 0.1, 0.01]]):
y=1.2
d={}
misc.dict_update(d, solution['mul'])
misc.dict_update(d,{'node':{'CS':{'rate': y}}})
misc.dict_update(d,{'nest':{'ST_GA_ampa':{'weight':b}}})
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
dd={'conn': {'GA_GA_gaba':{'fan_in0': 20,'rule':'all-all' },
'GA_GI_gaba':{'fan_in0': 2,' rule':'all-all' },
'GI_GA_gaba':{'fan_in0': 10,'rule':'all-all' },
'GI_GI_gaba':{'fan_in0': 28,'rule':'all-all' }}}
misc.dict_update(d, dd)
misc.dict_update(d,{'conn':{'GI_FS_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_FS_gaba':{'fan_in0': 2}}})
misc.dict_update(d,{'conn':{'GI_M1_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_M1_gaba':{'fan_in0': 2}}})
misc.dict_update(d,{'conn':{'GI_M2_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_M2_gaba':{'fan_in0': 2}}})
# d['node']['EA']['rate']*=0.9
# misc.dict_update(d,{'conn':{'M2_GA_gaba':{'lesion': False}}})
# misc.dict_update(d,{'conn':{'M2_GA_gaba':{'fan_in0': 25}}})
d['node']['EI']['rate']*=y*0.9
d['node']['EA']['rate']*=y*a
# d['node']['CS']['rate']*=y
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'all_EIEACS_'+str(a)+'_STGAw_'+str(b)})
return l
def get():
l=[]
solution=get_solution_slow_GP_striatum_2()
for y in numpy.arange(2.,29.,4.):
d={}
misc.dict_update(d, solution['mul'])
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
dd={'conn': {'GA_GA_gaba':{'fan_in0': y,'rule':'all-all' },
'GA_GI_gaba':{'fan_in0': 2,'rule':'all-all' },
'GI_GA_gaba':{'fan_in0': 30-y,'rule':'all-all' },
'GI_GI_gaba':{'fan_in0': 28,'rule':'all-all' }}}
misc.dict_update(d, dd)
l[-1]+=pl(d, '=', **{'name':'GAGA_'+str(y)+'_GIGA_'+str(30-y)})
d0=0.8
f_beta_rm=lambda f: (1-f)/(d0+f*(1-d0))
for y in [1.8, 2.0]:
d={}
misc.dict_update(d, solution['mul'])
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
d['node']['EI']['rate']*=y
d['node']['EA']['rate']*=y*0.7
misc.dict_update(d,{'nest':{'GI':{'beta_I_GABAA_1': f_beta_rm(2)}}})
l[-1]+=pl(d, '=', **{'name':'mod_EIEA_'+str(y)})
for y, EA_rate in zip(numpy.arange(25,80,25)
numpy.arange(0.9,1.1,0.1)):
d={}
misc.dict_update(d, solution['mul'])
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
d['node']['EA']['rate']*=EA_rate
misc.dict_update(d,{'conn':{'M2_GA_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'M2_GA_gaba':{'fan_in0': y}}})
l[-1]+=pl(d, '=', **{'name':'M2GA_'+str(y)+'_EArate_'+str(EA_rate)})
d['node']['EA']['rate']*=EA_rate
misc.dict_update(d,{'conn':{'M2_GA_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'M2_GA_gaba':{'fan_in0': y}}})
l[-1]+=pl(d, '=', **{'name':'M2GA_'+str(y)+'_EArate_'+str(EA_rate)})
for y in numpy.arange(2, 5, 2):
d={}
misc.dict_update(d, solution['mul'])
l+=[pl(d, '*', **{'name':''})]
d={}
misc.dict_update(d, solution['equal'])
misc.dict_update(d,{'conn':{'GI_FS_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_FS_gaba':{'fan_in0': y}}})
misc.dict_update(d,{'conn':{'GI_M1_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_M1_gaba':{'fan_in0': y}}})
misc.dict_update(d,{'conn':{'GI_M2_gaba':{'lesion': False}}})
misc.dict_update(d,{'conn':{'GI_M2_gaba':{'fan_in0': y}}})
l[-1]+=pl(d, '=', **{'name':'mod_GI_M2_'+str(y)})