def summarize_edge_lengths_on_tree(self,
tree,
split_distribution,
summarization_fn=None,
is_bipartitions_updated=False):
"""
Sets the lengths of edges on ``tree`` (a |Tree| object) to the mean
lengths of the corresponding edges on the input trees (in
``split_distribution``, a `SplitDistribution` object) being
summarized.
``summarization_fn`` should take an iterable of floats, and return a float. If |None|, it
defaults to calculating the mean (``lambda x: float(sum(x))/len(x)``).
"""
if summarization_fn is None:
summarization_fn = lambda x: float(sum(x))/len(x)
if not is_bipartitions_updated:
tree.encode_bipartitions()
for edge in tree.postorder_edge_iter():
split = edge.bipartition.split_bitmask
if (split in split_distribution.split_edge_lengths
and split_distribution.split_edge_lengths[split]):
lengths = split_distribution.split_edge_lengths[split]
edge.length = summarization_fn(lengths)
elif (split in split_distribution.split_edge_lengths
and not split_distribution.split_edge_lengths[split]):
# no input trees had any edge lengths for this split
edge.length = None
else:
# split on target tree that was not found in any of the input
# trees
edge.length = 0.0
return tree
## here we add the support values and/or edge lengths for the terminal taxa ##
for node in leaves:
if not is_rooted:
split = node.edge.split_bitmask
else:
split = node.edge.leafset_bitmask
self.map_split_support_to_node(node, 1.0)
if include_edge_lengths:
elen = split_distribution.split_edge_lengths.get(split, [0.0])
if len(elen) > 0:
mean, var = mean_and_sample_variance(elen)
node.edge.length = mean
if include_edge_length_var:
node.edge.length_var = var
else:
node.edge.length = None
if include_edge_length_var:
node.edge.length_var = None
#if include_edge_lengths:
#self.map_edge_lengths_to_tree(tree=con_tree,
# split_distribution=split_distribution,
# summarization_fn=summarization_fn,
# include_edge_length_var=False)
return con_tree
def summarize_edge_lengths_on_tree(self,
tree,
split_distribution,
summarization_fn=None,
is_bipartitions_updated=False):
"""
Sets the lengths of edges on ``tree`` (a |Tree| object) to the mean
lengths of the corresponding edges on the input trees (in
``split_distribution``, a `SplitDistribution` object) being
summarized.
``summarization_fn`` should take an iterable of floats, and return a float. If |None|, it
defaults to calculating the mean (``lambda x: float(sum(x))/len(x)``).
"""
if summarization_fn is None:
summarization_fn = lambda x: float(sum(x)) / len(x)
if not is_bipartitions_updated:
tree.encode_bipartitions()
for edge in tree.postorder_edge_iter():
split = edge.bipartition.split_bitmask
if (split in split_distribution.split_edge_lengths
and split_distribution.split_edge_lengths[split]):
lengths = split_distribution.split_edge_lengths[split]
edge.length = summarization_fn(lengths)
elif (split in split_distribution.split_edge_lengths
and not split_distribution.split_edge_lengths[split]):
# no input trees had any edge lengths for this split
edge.length = None
else:
# split on target tree that was not found in any of the input
# trees
edge.length = 0.0
return tree
## here we add the support values and/or edge lengths for the terminal taxa ##
for node in leaves:
if not is_rooted:
split = node.edge.split_bitmask
else:
split = node.edge.leafset_bitmask
self.map_split_support_to_node(node, 1.0)
if include_edge_lengths:
elen = split_distribution.split_edge_lengths.get(split, [0.0])
if len(elen) > 0:
mean, var = mean_and_sample_variance(elen)
node.edge.length = mean
if include_edge_length_var:
node.edge.length_var = var
else:
node.edge.length = None
if include_edge_length_var:
node.edge.length_var = None
#if include_edge_lengths:
#self.map_edge_lengths_to_tree(tree=con_tree,
# split_distribution=split_distribution,
# summarization_fn=summarization_fn,
# include_edge_length_var=False)
return con_tree
def _calculate_standardized_effect_size(self,
statisticf_name,
statisticf_kwargs=None,
assemblage_memberships=None,
null_model_type="taxa.label",
num_randomization_replicates=1000,
rng=None):
result_type = collections.namedtuple("PhylogeneticCommunityStandardizedEffectSizeStatisticCalculationResult",
["obs", "null_model_mean", "null_model_sd", "z", "rank", "p",])
if assemblage_memberships is None:
assemblage_memberships = [ set(self._mapped_taxa) ]
if statisticf_kwargs is None:
statisticf_kwargs = {}
observed_stat_values = {}
null_model_stat_values = {}
null_model_matrix = self.clone()
assert null_model_matrix == self
for rep_idx in range(num_randomization_replicates):
null_model_matrix.shuffle_taxa(rng=rng)
for community_idx, assemblage_membership in enumerate(assemblage_memberships):
filter_fn = lambda taxon: taxon in assemblage_membership
statisticf_kwargs["filter_fn"] = filter_fn
if rep_idx == 0:
observed_stat_values[community_idx] = getattr(self, statisticf_name)(**statisticf_kwargs)
null_model_stat_values[community_idx] = []
stat_value = getattr(null_model_matrix, statisticf_name)(**statisticf_kwargs)
null_model_stat_values[community_idx].append(stat_value)
results = []
for community_idx, assemblage_membership in enumerate(assemblage_memberships):
obs_value = observed_stat_values[community_idx]
stat_values = null_model_stat_values[community_idx]
null_model_mean, null_model_var = statistics.mean_and_sample_variance(stat_values)
rank = statistics.rank(
value_to_be_ranked=obs_value,
value_providing_rank=stat_values)
if null_model_var > 0:
null_model_sd = math.sqrt(null_model_var)
z = (obs_value - null_model_mean) / null_model_sd
else:
null_model_sd = 0.0
z = None
p = float(rank) / len(stat_values)
result = result_type(
obs=obs_value,
null_model_mean=null_model_mean,
null_model_sd=null_model_sd,
z=z,
rank=rank,
p=p)
results.append(result)
return results
def calc_rfd_distribution(src_path):
tns = dendropy.TaxonNamespace()
trees = dendropy.TreeList.get(
path=src_path,
schema="nexus")
rf_dists = []
for idx1, t1 in enumerate(trees[:-1]):
for idx2, t2 in enumerate(trees[idx1+1:]):
rfd = treecompare.unweighted_robinson_foulds_distance(t1, t2)
rf_dists.append(rfd)
mean, var = statistics.mean_and_sample_variance(rf_dists)
print("mean = {}, var = {}, 5/95% quantile = {}".format(
mean,
var,
statistics.quantile_5_95(rf_dists)))
def _calc_community_ecology_stats(self,
phylogenetic_distance_matrix,
assemblage_memberships,
assemblage_descriptions,
report_character_state_specific_results=True,
report_character_class_wide_results=True,
):
assert len(assemblage_descriptions) == len(assemblage_memberships)
summary_statistics_suite = {}
results_by_character_class = {}
stat_scores_to_be_harvested = ("obs", "z", "p",) # z = score, p = p-value (turns out this is quite informative)
for sstbh in stat_scores_to_be_harvested:
results_by_character_class[sstbh] = collections.defaultdict(list)
for edge_weighted_desc in ("unweighted", "weighted"):
if edge_weighted_desc:
is_weighted_edge_distances = True
else:
is_weighted_edge_distances = False
for underlying_statistic_type_desc in ("mpd", "mntd"):
if underlying_statistic_type_desc == "mpd":
stat_fn_name = "standardized_effect_size_mean_pairwise_distance"
else:
stat_fn_name = "standardized_effect_size_mean_nearest_taxon_distance"
stat_fn = getattr(phylogenetic_distance_matrix, stat_fn_name)
results_group = stat_fn(
assemblage_memberships=assemblage_memberships,
is_weighted_edge_distances=is_weighted_edge_distances,
is_normalize_by_tree_size=True,
num_randomization_replicates=self.num_randomization_replicates,
)
assert len(results_group) == len(assemblage_memberships)
for result, assemblage_desc in zip(results_group, assemblage_descriptions):
for ses_result_statistic in stat_scores_to_be_harvested:
character_class_statistic_prefix = self.stat_name_delimiter.join([
self.stat_name_prefix,
"community",
"by",
assemblage_desc["assemblage_basis_class_id"],
])
statistic_subtype_desc = self.stat_name_delimiter.join([
edge_weighted_desc,
underlying_statistic_type_desc,
# assemblage_desc["assemblage_basis_state_id"],
])
character_class_statistic_key = tuple([character_class_statistic_prefix, statistic_subtype_desc])
ses_result_statistic_value = getattr(result, ses_result_statistic)
if ses_result_statistic_value is None:
continue
if report_character_state_specific_results:
character_state_statistic_name = self.stat_name_delimiter.join([
character_class_statistic_prefix,
assemblage_desc["assemblage_basis_state_id"],
statistic_subtype_desc,
ses_result_statistic,
])
assert character_state_statistic_name not in summary_statistics_suite
summary_statistics_suite[character_state_statistic_name] = ses_result_statistic_value
if report_character_class_wide_results:
results_by_character_class[ses_result_statistic][character_class_statistic_key].append(ses_result_statistic_value)
if report_character_class_wide_results:
for ses_result_statistic in results_by_character_class:
if len(results_by_character_class[ses_result_statistic]) == 0:
continue
for key in results_by_character_class[ses_result_statistic]:
character_class_statistic_prefix, statistic_subtype_desc = key
svalues = results_by_character_class[ses_result_statistic][key]
mean_var = statistics.mean_and_sample_variance(svalues)
for s, sdesc in zip( mean_var, ("mean", "var"), ):
sn_title = self.stat_name_delimiter.join([
character_class_statistic_prefix,
sdesc,
statistic_subtype_desc,
ses_result_statistic,
])
assert sn_title not in summary_statistics_suite
summary_statistics_suite[sn_title] = s
return summary_statistics_suite
import collections
import dendropy
from dendropy.calculate import treemeasure
from dendropy.calculate import statistics
# Since we do not want to waste memory by keeping the actual trees around
# after we are done calculating the statistics, we use the tree yielder
# instead of:
# dendropy.TreeList.get(
# path="pythonidae.beast-mcmc.trees",
# schema="nexus",
# tree_offset=200)
tree_stats = collections.defaultdict(list)
for tree_idx, tree in enumerate(dendropy.Tree.yield_from_files(
files=["pythonidae.beast-mcmc.trees"],
schema="nexus")):
if tree_idx < 200:
continue # burnin
tree_stats["B1"].append(treemeasure.B1(tree))
tree_stats["colless"].append(treemeasure.colless_tree_imbalance(tree))
tree_stats["PBH"].append(treemeasure.pybus_harvey_gamma(tree))
tree_stats["sackin"].append(treemeasure.sackin_index(tree))
tree_stats["treeness"].append(treemeasure.treeness(tree))
for key in tree_stats:
values = tree_stats[key]
mean, var = statistics.mean_and_sample_variance(values)
hpd = statistics.empirical_hpd(values)
print("{:15}: mean = {}, variance = {}, hpd = ({}, {})".format(key, mean, var, hpd[0], hpd[1]))
def _calc_community_ecology_stats(
self,
phylogenetic_distance_matrix,
assemblage_memberships,
assemblage_descriptions,
report_character_state_specific_results=True,
report_character_class_wide_results=True,
):
assert len(assemblage_descriptions) == len(assemblage_memberships)
summary_statistics_suite = collections.OrderedDict()
results_by_character_class = collections.OrderedDict()
stat_scores_to_be_harvested = (
"obs",
"z",
"p",
) # z = score, p = p-value (turns out this is quite informative)
for sstbh in stat_scores_to_be_harvested:
results_by_character_class[sstbh] = collections.defaultdict(list)
for edge_weighted_desc in ("unweighted", "weighted"):
if edge_weighted_desc:
is_weighted_edge_distances = True
else:
is_weighted_edge_distances = False
for underlying_statistic_type_desc in ("mpd", "mntd"):
if underlying_statistic_type_desc == "mpd":
stat_fn_name = "standardized_effect_size_mean_pairwise_distance"
else:
stat_fn_name = "standardized_effect_size_mean_nearest_taxon_distance"
stat_fn = getattr(phylogenetic_distance_matrix, stat_fn_name)
try:
results_group = stat_fn(
assemblage_memberships=assemblage_memberships,
is_weighted_edge_distances=is_weighted_edge_distances,
is_normalize_by_tree_size=True,
num_randomization_replicates=self.
num_randomization_replicates,
)
except dendropy.utility.error.SingleTaxonAssemblageException as e:
if not report_character_state_specific_results:
continue
else:
raise
if not report_character_state_specific_results:
assert len(results_group) == len(assemblage_memberships)
if len(results_group) == 0:
raise error.IncompleteStateSpaceOccupancyException
for result, assemblage_desc in zip(results_group,
assemblage_descriptions):
for ses_result_statistic in stat_scores_to_be_harvested:
character_class_statistic_prefix = self.stat_name_delimiter.join(
[
self.stat_name_prefix,
"community",
"by",
assemblage_desc["assemblage_basis_class_id"],
])
statistic_subtype_desc = self.stat_name_delimiter.join(
[
edge_weighted_desc,
underlying_statistic_type_desc,
# assemblage_desc["assemblage_basis_state_id"],
])
character_class_statistic_key = tuple([
character_class_statistic_prefix,
statistic_subtype_desc
])
ses_result_statistic_value = getattr(
result, ses_result_statistic)
if ses_result_statistic_value is None:
continue
if report_character_state_specific_results:
character_state_statistic_name = self.stat_name_delimiter.join(
[
character_class_statistic_prefix,
assemblage_desc[
"assemblage_basis_state_id"],
statistic_subtype_desc,
ses_result_statistic,
])
assert character_state_statistic_name not in summary_statistics_suite
summary_statistics_suite[
character_state_statistic_name] = ses_result_statistic_value
if report_character_class_wide_results:
results_by_character_class[ses_result_statistic][
character_class_statistic_key].append(
ses_result_statistic_value)
if report_character_class_wide_results:
for ses_result_statistic in results_by_character_class:
if len(results_by_character_class[ses_result_statistic]) == 0:
continue
for key in results_by_character_class[ses_result_statistic]:
character_class_statistic_prefix, statistic_subtype_desc = key
svalues = results_by_character_class[ses_result_statistic][
key]
mean_var = statistics.mean_and_sample_variance(svalues)
for s, sdesc in zip(
mean_var,
("mean", "var"),
):
sn_title = self.stat_name_delimiter.join([
character_class_statistic_prefix,
sdesc,
statistic_subtype_desc,
ses_result_statistic,
])
assert sn_title not in summary_statistics_suite
summary_statistics_suite[sn_title] = s
return summary_statistics_suite
def tree_from_splits(self,
split_distribution,
min_freq=0.5,
rooted=None,
include_edge_lengths=True):
"""Returns a consensus tree from splits in ``split_distribution``.
If include_edge_length_var is True, then the sample variance of the
edge length will also be calculated and will be stored as
a length_var attribute.
"""
taxon_namespace = split_distribution.taxon_namespace
taxa_mask = taxon_namespace.all_taxa_bitmask()
if self.weighted_splits:
split_freqs = split_distribution.weighted_split_frequencies
else:
split_freqs = split_distribution.split_frequencies
if rooted is None:
if split_distribution.is_all_counted_trees_rooted():
rooted = True
elif split_distribution.is_all_counted_trees_strictly_unrooted:
rooted = False
#include_edge_lengths = self.support_as_labels and include_edge_lengths
if self.support_as_edge_lengths and include_edge_lengths:
raise Exception("Cannot map support as edge lengths if edge lengths are to be set on consensus tree")
to_try_to_add = []
_almost_one = lambda x: abs(x - 1.0) <= 0.0000001
for s in split_freqs:
freq = split_freqs[s]
if (min_freq is None) or (freq >= min_freq) or (_almost_one(min_freq) and _almost_one(freq)):
to_try_to_add.append((freq, s))
to_try_to_add.sort(reverse=True)
splits_for_tree = [i[1] for i in to_try_to_add]
con_tree = dendropy.Tree.from_split_bitmasks(
split_bitmasks=splits_for_tree,
taxon_namespace=taxon_namespace,
is_rooted=rooted)
con_tree.encode_bipartitions()
if include_edge_lengths:
split_edge_lengths = {}
for split, edges in split_distribution.split_edge_lengths.items():
if len(edges) > 0:
mean, var = mean_and_sample_variance(edges)
elen = mean
else:
elen = None
split_edge_lengths[split] = elen
else:
split_edge_lengths = None
for node in con_tree.postorder_node_iter():
split = node.edge.bipartition.split_bitmask
if split in split_freqs:
self.map_split_support_to_node(node=node, split_support=split_freqs[split])
if include_edge_lengths and split in split_distribution.split_edge_lengths:
edges = split_distribution.split_edge_lengths[split]
if len(edges) > 0:
mean, var = mean_and_sample_variance(edges)
elen = mean
else:
elen = None
node.edge.length = elen
return con_tree
def tree_from_splits(self,
split_distribution,
min_freq=0.5,
rooted=None,
include_edge_lengths=True):
"""Returns a consensus tree from splits in ``split_distribution``.
If include_edge_length_var is True, then the sample variance of the
edge length will also be calculated and will be stored as
a length_var attribute.
"""
taxon_namespace = split_distribution.taxon_namespace
taxa_mask = taxon_namespace.all_taxa_bitmask()
if self.weighted_splits:
split_freqs = split_distribution.weighted_split_frequencies
else:
split_freqs = split_distribution.split_frequencies
if rooted is None:
if split_distribution.is_all_counted_trees_rooted():
rooted = True
elif split_distribution.is_all_counted_trees_strictly_unrooted:
rooted = False
#include_edge_lengths = self.support_as_labels and include_edge_lengths
if self.support_as_edge_lengths and include_edge_lengths:
raise Exception(
"Cannot map support as edge lengths if edge lengths are to be set on consensus tree"
)
to_try_to_add = []
_almost_one = lambda x: abs(x - 1.0) <= 0.0000001
for s in split_freqs:
freq = split_freqs[s]
if (min_freq is None) or (freq >= min_freq) or (
_almost_one(min_freq) and _almost_one(freq)):
to_try_to_add.append((freq, s))
to_try_to_add.sort(reverse=True)
splits_for_tree = [i[1] for i in to_try_to_add]
con_tree = dendropy.Tree.from_split_bitmasks(
split_bitmasks=splits_for_tree,
taxon_namespace=taxon_namespace,
is_rooted=rooted)
con_tree.encode_bipartitions()
if include_edge_lengths:
split_edge_lengths = {}
for split, edges in split_distribution.split_edge_lengths.items():
if len(edges) > 0:
mean, var = mean_and_sample_variance(edges)
elen = mean
else:
elen = None
split_edge_lengths[split] = elen
else:
split_edge_lengths = None
for node in con_tree.postorder_node_iter():
split = node.edge.bipartition.split_bitmask
if split in split_freqs:
self.map_split_support_to_node(
node=node, split_support=split_freqs[split])
if include_edge_lengths and split in split_distribution.split_edge_lengths:
edges = split_distribution.split_edge_lengths[split]
if len(edges) > 0:
mean, var = mean_and_sample_variance(edges)
elen = mean
else:
elen = None
node.edge.length = elen
return con_tree
import dendropy
from dendropy.calculate import treemeasure
from dendropy.calculate import statistics
# Since we do not want to waste memory by keeping the actual trees around
# after we are done calculating the statistics, we use the tree yielder
# instead of:
# dendropy.TreeList.get(
# path="pythonidae.beast-mcmc.trees",
# schema="nexus",
# tree_offset=200)
tree_stats = collections.defaultdict(list)
for tree_idx, tree in enumerate(
dendropy.Tree.yield_from_files(files=["pythonidae.beast-mcmc.trees"],
schema="nexus")):
if tree_idx < 200:
continue # burnin
tree_stats["B1"].append(treemeasure.B1(tree))
tree_stats["colless"].append(treemeasure.colless_tree_imbalance(tree))
tree_stats["PBH"].append(treemeasure.pybus_harvey_gamma(tree))
tree_stats["sackin"].append(treemeasure.sackin_index(tree))
tree_stats["treeness"].append(treemeasure.treeness(tree))
for key in tree_stats:
values = tree_stats[key]
mean, var = statistics.mean_and_sample_variance(values)
hpd = statistics.empirical_hpd(values)
print("{:15}: mean = {}, variance = {}, hpd = ({}, {})".format(
key, mean, var, hpd[0], hpd[1]))
