Beispiel #1
0
def current(loci, ail):
    cell = nm.NeuronModel(dl=1000, dd=2,  sl=40, sd=20,\
           hl=10, hd=2, ail=ail, aid=1.2, axl=1000, axd=1.2,\
           dna=100, sna=100, hna=300, aina=4000, axna=300, dk=20,\
           sk=20, hk=150, aik=1000, axk=150,\
           na_type=7, aina12=1000, aina16=1000)
    stim = nm.attach_current_clamp(cell, amp=1, dur=1)
    vec = nm.set_recording_vectors(cell)
    v = h.Vector()
    v.record(cell.ais(loci)._ref_v)

    icap = h.Vector()  # (mA/cm2)
    icap.record(cell.ais(loci)._ref_i_cap)

    ileak = h.Vector()  # (mA/cm2)
    ileak.record(cell.ais(loci)._ref_i_pas)

    ina = h.Vector()  # (mA/cm2)
    ina.record(cell.ais(loci)._ref_ina)

    ik = h.Vector()  # (mA/cm2)
    ik.record(cell.ais(loci)._ref_ik)

    nm.simulate()
    print(nm.cal_velocity(vec, ["ais"]))

    iax = -np.array(icap.to_python()) - np.array(ileak.to_python()) - np.array(
        ina.to_python()) - np.array(ik.to_python())

    cell.dend1 = None
    cell.soma = None
    cell.hill = None
    cell.ais = None
    cell.axon = None
    for sec in h.allsec():
        print(sec)
    return v, icap, ileak, ina, ik, iax
     for j, l in enumerate(len_x):
         file_name = 'type'+str(na_type)\
            +'_aina12_'+str(aina12_x[p])\
            +'_aina16_'+str(aina16_x[p])\
            +'_aik_'+str(aik_x[p])\
            +'_dist_'+str(d)+'_len_'+str(l)+'_v_vec.p'
         print(na_type, p, d, l)
         cell = nm.NeuronModel(hl=int(d),\
                   ail=int(l),\
                na_type=na_type,\
                aina12=aina12_x[p],\
                aina16=aina16_x[p],\
                aik=aik_x[p])
         stim = nm.attach_current_clamp(cell, amp=.7)
         vec = nm.set_recording_vectors(cell)
         nm.simulate()
         nm.save_vec(vec, save_data_path + file_name)
         nm.show_output(vec, save_figure_path + file_name)
         bpv_sum[i, j], fwv_sum[i,
                                j], ___ = nm.cal_velocity(vec, ['ais'])
         cell.dend1 = None
         cell.dend2 = None
         cell.soma = None
         cell.hill = None
         cell.ais = None
         cell.axon = None
         for sec in h.allsec():
             print(sec)
 with open(save_data_path+'type'+str(na_type)\
      +'_aina12_'+str(aina12_x[p])\
      +'_aina16_'+str(aina16_x[p])\