class tuframeworkTrainerV2_3ConvPerStage(tuframeworkTrainerV2):
def initialize_network(self):
self.base_num_features = 24 # otherwise we run out of VRAM
if self.threeD:
conv_op = nn.Conv3d
dropout_op = nn.Dropout3d
norm_op = nn.InstanceNorm3d
else:
conv_op = nn.Conv2d
dropout_op = nn.Dropout2d
norm_op = nn.InstanceNorm2d
norm_op_kwargs = {'eps': 1e-5, 'affine': True}
dropout_op_kwargs = {'p': 0, 'inplace': True}
net_nonlin = nn.LeakyReLU
net_nonlin_kwargs = {'negative_slope': 1e-2, 'inplace': True}
self.network = Generic_UNet(self.num_input_channels, self.base_num_features, self.num_classes,
len(self.net_num_pool_op_kernel_sizes),
3, 2, conv_op, norm_op, norm_op_kwargs, dropout_op, dropout_op_kwargs,
net_nonlin, net_nonlin_kwargs, True, False, lambda x: x, InitWeights_He(1e-2),
self.net_num_pool_op_kernel_sizes, self.net_conv_kernel_sizes, False, True, True)
if torch.cuda.is_available():
self.network.cuda()
self.network.inference_apply_nonlin = softmax_helper
class tuframeworkTrainerV2_BN(tuframeworkTrainerV2):
def initialize_network(self):
"""
changed deep supervision to False
:return:
"""
if self.threeD:
conv_op = nn.Conv3d
dropout_op = nn.Dropout3d
norm_op = nn.BatchNorm3d
else:
conv_op = nn.Conv2d
dropout_op = nn.Dropout2d
norm_op = nn.BatchNorm2d
norm_op_kwargs = {'eps': 1e-5, 'affine': True}
dropout_op_kwargs = {'p': 0, 'inplace': True}
net_nonlin = nn.LeakyReLU
net_nonlin_kwargs = {'negative_slope': 1e-2, 'inplace': True}
self.network = Generic_UNet(
self.num_input_channels, self.base_num_features, self.num_classes,
len(self.net_num_pool_op_kernel_sizes), self.conv_per_stage, 2,
conv_op, norm_op, norm_op_kwargs, dropout_op, dropout_op_kwargs,
net_nonlin, net_nonlin_kwargs, True, False, lambda x: x,
InitWeights_He(1e-2), self.net_num_pool_op_kernel_sizes,
self.net_conv_kernel_sizes, False, True, True)
if torch.cuda.is_available():
self.network.cuda()
self.network.inference_apply_nonlin = softmax_helper
class tuframeworkTrainerV2_Mish(tuframeworkTrainerV2):
def initialize_network(self):
if self.threeD:
conv_op = nn.Conv3d
dropout_op = nn.Dropout3d
norm_op = nn.InstanceNorm3d
else:
conv_op = nn.Conv2d
dropout_op = nn.Dropout2d
norm_op = nn.InstanceNorm2d
norm_op_kwargs = {'eps': 1e-5, 'affine': True}
dropout_op_kwargs = {'p': 0, 'inplace': True}
net_nonlin = Mish
net_nonlin_kwargs = {}
self.network = Generic_UNet(
self.num_input_channels, self.base_num_features, self.num_classes,
len(self.net_num_pool_op_kernel_sizes), self.conv_per_stage, 2,
conv_op, norm_op, norm_op_kwargs, dropout_op, dropout_op_kwargs,
net_nonlin, net_nonlin_kwargs, True, False, lambda x: x,
InitWeights_He(0), self.net_num_pool_op_kernel_sizes,
self.net_conv_kernel_sizes, False, True, True)
if torch.cuda.is_available():
self.network.cuda()
self.network.inference_apply_nonlin = softmax_helper
class tuframeworkTrainerV2_MMS(tuframeworkTrainerV2_insaneDA):
def setup_DA_params(self):
super().setup_DA_params()
self.data_aug_params["p_rot"] = 0.7
self.data_aug_params["p_eldef"] = 0.1
self.data_aug_params["p_scale"] = 0.3
self.data_aug_params["independent_scale_factor_for_each_axis"] = True
self.data_aug_params["p_independent_scale_per_axis"] = 0.3
self.data_aug_params["do_additive_brightness"] = True
self.data_aug_params["additive_brightness_mu"] = 0
self.data_aug_params["additive_brightness_sigma"] = 0.2
self.data_aug_params["additive_brightness_p_per_sample"] = 0.3
self.data_aug_params["additive_brightness_p_per_channel"] = 1
self.data_aug_params["elastic_deform_alpha"] = (0., 300.)
self.data_aug_params["elastic_deform_sigma"] = (9., 15.)
self.data_aug_params['gamma_range'] = (0.5, 1.6)
def initialize_network(self):
if self.threeD:
conv_op = nn.Conv3d
dropout_op = nn.Dropout3d
norm_op = nn.BatchNorm3d
else:
conv_op = nn.Conv2d
dropout_op = nn.Dropout2d
norm_op = nn.BatchNorm2d
norm_op_kwargs = {'eps': 1e-5, 'affine': True}
dropout_op_kwargs = {'p': 0, 'inplace': True}
net_nonlin = nn.LeakyReLU
net_nonlin_kwargs = {'negative_slope': 1e-2, 'inplace': True}
self.network = Generic_UNet(
self.num_input_channels, self.base_num_features, self.num_classes,
len(self.net_num_pool_op_kernel_sizes), self.conv_per_stage, 2,
conv_op, norm_op, norm_op_kwargs, dropout_op, dropout_op_kwargs,
net_nonlin, net_nonlin_kwargs, True, False, lambda x: x,
InitWeights_He(1e-2), self.net_num_pool_op_kernel_sizes,
self.net_conv_kernel_sizes, False, True, True)
if torch.cuda.is_available():
self.network.cuda()
self.network.inference_apply_nonlin = softmax_helper
"""def run_training(self):
class tuframeworkTrainerV2_allConv3x3(tuframeworkTrainerV2):
def initialize_network(self):
"""
- momentum 0.99
- SGD instead of Adam
- self.lr_scheduler = None because we do poly_lr
- deep supervision = True
- i am sure I forgot something here
Known issue: forgot to set neg_slope=0 in InitWeights_He; should not make a difference though
:return:
"""
if self.threeD:
conv_op = nn.Conv3d
dropout_op = nn.Dropout3d
norm_op = nn.InstanceNorm3d
else:
conv_op = nn.Conv2d
dropout_op = nn.Dropout2d
norm_op = nn.InstanceNorm2d
for s in range(len(self.net_conv_kernel_sizes)):
for i in range(len(self.net_conv_kernel_sizes[s])):
self.net_conv_kernel_sizes[s][i] = 3
norm_op_kwargs = {'eps': 1e-5, 'affine': True}
dropout_op_kwargs = {'p': 0, 'inplace': True}
net_nonlin = nn.LeakyReLU
net_nonlin_kwargs = {'negative_slope': 1e-2, 'inplace': True}
self.network = Generic_UNet(
self.num_input_channels, self.base_num_features, self.num_classes,
len(self.net_num_pool_op_kernel_sizes), self.conv_per_stage, 2,
conv_op, norm_op, norm_op_kwargs, dropout_op, dropout_op_kwargs,
net_nonlin, net_nonlin_kwargs, True, False, lambda x: x,
InitWeights_He(1e-2), self.net_num_pool_op_kernel_sizes,
self.net_conv_kernel_sizes, False, True, True)
if torch.cuda.is_available():
self.network.cuda()
self.network.inference_apply_nonlin = softmax_helper
class tuframeworkTrainerV2_noDeepSupervision(tuframeworkTrainerV2):
def __init__(self,
plans_file,
fold,
output_folder=None,
dataset_directory=None,
batch_dice=True,
stage=None,
unpack_data=True,
deterministic=True,
fp16=False):
super().__init__(plans_file, fold, output_folder, dataset_directory,
batch_dice, stage, unpack_data, deterministic, fp16)
self.loss = DC_and_CE_loss(
{
'batch_dice': self.batch_dice,
'smooth': 1e-5,
'do_bg': False
}, {})
def setup_DA_params(self):
"""
we leave out the creation of self.deep_supervision_scales, so it remains None
:return:
"""
if self.threeD:
self.data_aug_params = default_3D_augmentation_params
self.data_aug_params['rotation_x'] = (-30. / 360 * 2. * np.pi,
30. / 360 * 2. * np.pi)
self.data_aug_params['rotation_y'] = (-30. / 360 * 2. * np.pi,
30. / 360 * 2. * np.pi)
self.data_aug_params['rotation_z'] = (-30. / 360 * 2. * np.pi,
30. / 360 * 2. * np.pi)
if self.do_dummy_2D_aug:
self.data_aug_params["dummy_2D"] = True
self.print_to_log_file("Using dummy2d data augmentation")
self.data_aug_params["elastic_deform_alpha"] = \
default_2D_augmentation_params["elastic_deform_alpha"]
self.data_aug_params["elastic_deform_sigma"] = \
default_2D_augmentation_params["elastic_deform_sigma"]
self.data_aug_params[
"rotation_x"] = default_2D_augmentation_params[
"rotation_x"]
else:
self.do_dummy_2D_aug = False
if max(self.patch_size) / min(self.patch_size) > 1.5:
default_2D_augmentation_params['rotation_x'] = (-15. / 360 *
2. * np.pi,
15. / 360 *
2. * np.pi)
self.data_aug_params = default_2D_augmentation_params
self.data_aug_params[
"mask_was_used_for_normalization"] = self.use_mask_for_norm
if self.do_dummy_2D_aug:
self.basic_generator_patch_size = get_patch_size(
self.patch_size[1:], self.data_aug_params['rotation_x'],
self.data_aug_params['rotation_y'],
self.data_aug_params['rotation_z'],
self.data_aug_params['scale_range'])
self.basic_generator_patch_size = np.array(
[self.patch_size[0]] + list(self.basic_generator_patch_size))
patch_size_for_spatialtransform = self.patch_size[1:]
else:
self.basic_generator_patch_size = get_patch_size(
self.patch_size, self.data_aug_params['rotation_x'],
self.data_aug_params['rotation_y'],
self.data_aug_params['rotation_z'],
self.data_aug_params['scale_range'])
patch_size_for_spatialtransform = self.patch_size
self.data_aug_params["scale_range"] = (0.7, 1.4)
self.data_aug_params["do_elastic"] = False
self.data_aug_params['selected_seg_channels'] = [0]
self.data_aug_params[
'patch_size_for_spatialtransform'] = patch_size_for_spatialtransform
def initialize(self, training=True, force_load_plans=False):
"""
removed deep supervision
:return:
"""
if not self.was_initialized:
if not os.path.isdir(self.output_folder):
os.makedirs(self.output_folder)
if force_load_plans or (self.plans is None):
self.load_plans_file()
self.process_plans(self.plans)
self.setup_DA_params()
self.folder_with_preprocessed_data = self.dataset_directory + "/" + self.plans[
'data_identifier'] + "_stage%d" % self.stage
if training:
self.dl_tr, self.dl_val = self.get_basic_generators()
if self.unpack_data:
print("unpacking dataset")
unpack_dataset(self.folder_with_preprocessed_data)
print("done")
else:
print(
"INFO: Not unpacking data! Training may be slow due to that. Pray you are not using 2d or you "
"will wait all winter for your model to finish!")
assert self.deep_supervision_scales is None
self.tr_gen, self.val_gen = get_moreDA_augmentation(
self.dl_tr,
self.dl_val,
self.data_aug_params['patch_size_for_spatialtransform'],
self.data_aug_params,
deep_supervision_scales=self.deep_supervision_scales,
classes=None,
pin_memory=self.pin_memory)
self.print_to_log_file("TRAINING KEYS:\n %s" %
(str(self.dataset_tr.keys())),
also_print_to_console=False)
self.print_to_log_file("VALIDATION KEYS:\n %s" %
(str(self.dataset_val.keys())),
also_print_to_console=False)
else:
pass
self.initialize_network()
self.initialize_optimizer_and_scheduler()
assert isinstance(self.network,
(SegmentationNetwork, nn.DataParallel))
else:
self.print_to_log_file(
'self.was_initialized is True, not running self.initialize again'
)
self.was_initialized = True
def initialize_network(self):
"""
changed deep supervision to False
:return:
"""
if self.threeD:
conv_op = nn.Conv3d
dropout_op = nn.Dropout3d
norm_op = nn.InstanceNorm3d
else:
conv_op = nn.Conv2d
dropout_op = nn.Dropout2d
norm_op = nn.InstanceNorm2d
norm_op_kwargs = {'eps': 1e-5, 'affine': True}
dropout_op_kwargs = {'p': 0, 'inplace': True}
net_nonlin = nn.LeakyReLU
net_nonlin_kwargs = {'negative_slope': 1e-2, 'inplace': True}
self.network = Generic_UNet(
self.num_input_channels, self.base_num_features, self.num_classes,
len(self.net_num_pool_op_kernel_sizes), self.conv_per_stage, 2,
conv_op, norm_op, norm_op_kwargs, dropout_op, dropout_op_kwargs,
net_nonlin, net_nonlin_kwargs, False, False, lambda x: x,
InitWeights_He(1e-2), self.net_num_pool_op_kernel_sizes,
self.net_conv_kernel_sizes, False, True, True)
if torch.cuda.is_available():
self.network.cuda()
self.network.inference_apply_nonlin = softmax_helper
def run_online_evaluation(self, output, target):
return tuframeworkTrainer.run_online_evaluation(self, output, target)
class pixelCL_seg_Trainer(NetworkTrainer):
def __init__(self, plans_file, fold, output_folder=None, dataset_directory=None, batch_dice=True, stage=None,
unpack_data=True, deterministic=True, fp16=False):
"""
:param deterministic:
:param fold: can be either [0 ... 5) for cross-validation, 'all' to train on all available training data or
None if you wish to load some checkpoint and do inference only
:param plans_file: the pkl file generated by preprocessing. This file will determine all design choices
:param subfolder_with_preprocessed_data: must be a subfolder of dataset_directory (just the name of the folder,
not the entire path). This is where the preprocessed data lies that will be used for network training. We made
this explicitly available so that differently preprocessed data can coexist and the user can choose what to use.
Can be None if you are doing inference only.
:param output_folder: where to store parameters, plot progress and to the validation
:param dataset_directory: the parent directory in which the preprocessed Task data is stored. This is required
because the split information is stored in this directory. For running prediction only this input is not
required and may be set to None
:param batch_dice: compute dice loss for each sample and average over all samples in the batch or pretend the
batch is a pseudo volume?
:param stage: The plans file may contain several stages (used for lowres / highres / pyramid). Stage must be
specified for training:
if stage 1 exists then stage 1 is the high resolution stage, otherwise it's 0
:param unpack_data: if False, npz preprocessed data will not be unpacked to npy. This consumes less space but
is considerably slower! Running unpack_data=False with 2d should never be done!
IMPORTANT: If you inherit from tuframeworkTrainer and the init args change then you need to redefine self.init_args
in your init accordingly. Otherwise checkpoints won't load properly!
"""
super(pixelCL_seg_Trainer, self).__init__(deterministic, fp16)
self.unpack_data = unpack_data
self.init_args = (plans_file, fold, output_folder, dataset_directory, batch_dice, stage, unpack_data,
deterministic, fp16)
# set through arguments from init
self.stage = stage
self.experiment_name = self.__class__.__name__
self.plans_file = plans_file
self.output_folder = output_folder
self.dataset_directory = dataset_directory
self.output_folder_base = self.output_folder
self.fold = fold
self.plans = None
# if we are running inference only then the self.dataset_directory is set (due to checkpoint loading) but it
# irrelevant
if self.dataset_directory is not None and isdir(self.dataset_directory):
self.gt_niftis_folder = join(self.dataset_directory, "gt_segmentations")
else:
self.gt_niftis_folder = None
self.folder_with_preprocessed_data = None
# set in self.initialize()
self.dl_tr = self.dl_val = None
self.num_input_channels = self.num_classes = self.net_pool_per_axis = self.patch_size = self.batch_size = \
self.threeD = self.base_num_features = self.intensity_properties = self.normalization_schemes = \
self.net_num_pool_op_kernel_sizes = self.net_conv_kernel_sizes = None # loaded automatically from plans_file
self.basic_generator_patch_size = self.data_aug_params = self.transpose_forward = self.transpose_backward = None
self.batch_dice = batch_dice
self.loss = DC_and_CE_loss({'batch_dice': self.batch_dice, 'smooth': 1e-5, 'do_bg': False}, {})
self.online_eval_foreground_dc = []
self.online_eval_tp = []
self.online_eval_fp = []
self.online_eval_fn = []
self.classes = self.do_dummy_2D_aug = self.use_mask_for_norm = self.only_keep_largest_connected_component = \
self.min_region_size_per_class = self.min_size_per_class = None
self.inference_pad_border_mode = "constant"
self.inference_pad_kwargs = {'constant_values': 0}
self.update_fold(fold)
self.pad_all_sides = None
self.lr_scheduler_eps = 1e-3
self.lr_scheduler_patience = 30
self.initial_lr = 3e-4
self.weight_decay = 3e-5
self.oversample_foreground_percent = 0.33
self.conv_per_stage = None
self.regions_class_order = None
def update_fold(self, fold):
"""
used to swap between folds for inference (ensemble of models from cross-validation)
DO NOT USE DURING TRAINING AS THIS WILL NOT UPDATE THE DATASET SPLIT AND THE DATA AUGMENTATION GENERATORS
:param fold:
:return:
"""
if fold is not None:
if isinstance(fold, str):
assert fold == "all", "if self.fold is a string then it must be \'all\'"
if self.output_folder.endswith("%s" % str(self.fold)):
self.output_folder = self.output_folder_base
self.output_folder = join(self.output_folder, "%s" % str(fold))
else:
if self.output_folder.endswith("fold_%s" % str(self.fold)):
self.output_folder = self.output_folder_base
self.output_folder = join(self.output_folder, "fold_%s" % str(fold))
self.fold = fold
def setup_DA_params(self):
if self.threeD:
self.data_aug_params = default_3D_augmentation_params
if self.do_dummy_2D_aug:
self.data_aug_params["dummy_2D"] = True
self.print_to_log_file("Using dummy2d data augmentation")
self.data_aug_params["elastic_deform_alpha"] = \
default_2D_augmentation_params["elastic_deform_alpha"]
self.data_aug_params["elastic_deform_sigma"] = \
default_2D_augmentation_params["elastic_deform_sigma"]
self.data_aug_params["rotation_x"] = default_2D_augmentation_params["rotation_x"]
else:
self.do_dummy_2D_aug = False
if max(self.patch_size) / min(self.patch_size) > 1.5:
default_2D_augmentation_params['rotation_x'] = (-15. / 360 * 2. * np.pi, 15. / 360 * 2. * np.pi)
self.data_aug_params = default_2D_augmentation_params
self.data_aug_params["mask_was_used_for_normalization"] = self.use_mask_for_norm
if self.do_dummy_2D_aug:
self.basic_generator_patch_size = get_patch_size(self.patch_size[1:],
self.data_aug_params['rotation_x'],
self.data_aug_params['rotation_y'],
self.data_aug_params['rotation_z'],
self.data_aug_params['scale_range'])
self.basic_generator_patch_size = np.array([self.patch_size[0]] + list(self.basic_generator_patch_size))
patch_size_for_spatialtransform = self.patch_size[1:]
else:
self.basic_generator_patch_size = get_patch_size(self.patch_size, self.data_aug_params['rotation_x'],
self.data_aug_params['rotation_y'],
self.data_aug_params['rotation_z'],
self.data_aug_params['scale_range'])
patch_size_for_spatialtransform = self.patch_size
self.data_aug_params['selected_seg_channels'] = [0]
self.data_aug_params['patch_size_for_spatialtransform'] = patch_size_for_spatialtransform
def initialize(self, training=True, force_load_plans=False):
"""
For prediction of test cases just set training=False, this will prevent loading of training data and
training batchgenerator initialization
:param training:
:return:
"""
if not os.path.isdir(self.output_folder):os.makedirs(self.output_folder)
if force_load_plans or (self.plans is None):
self.load_plans_file()
self.process_plans(self.plans)
self.setup_DA_params()
if training:
self.folder_with_preprocessed_data = join(self.dataset_directory, self.plans['data_identifier'] +
"_stage%d" % self.stage)
self.dl_tr, self.dl_val = self.get_basic_generators()
if self.unpack_data:
self.print_to_log_file("unpacking dataset")
unpack_dataset(self.folder_with_preprocessed_data)
self.print_to_log_file("done")
else:
self.print_to_log_file(
"INFO: Not unpacking data! Training may be slow due to that. Pray you are not using 2d or you "
"will wait all winter for your model to finish!")
self.tr_gen, self.val_gen = get_default_augmentation(self.dl_tr, self.dl_val,
self.data_aug_params[
'patch_size_for_spatialtransform'],
self.data_aug_params)
self.print_to_log_file("TRAINING KEYS:\n %s" % (str(self.dataset_tr.keys())),
also_print_to_console=False)
self.print_to_log_file("VALIDATION KEYS:\n %s" % (str(self.dataset_val.keys())),
also_print_to_console=False)
else:
pass
self.initialize_network()
self.initialize_optimizer_and_scheduler()
# assert isinstance(self.network, (SegmentationNetwork, nn.DataParallel))
self.was_initialized = True
def initialize_network(self):
"""
This is specific to the U-Net and must be adapted for other network architectures
:return:
"""
# self.print_to_log_file(self.net_num_pool_op_kernel_sizes)
# self.print_to_log_file(self.net_conv_kernel_sizes)
net_numpool = len(self.net_num_pool_op_kernel_sizes)
if self.threeD:
conv_op = nn.Conv3d
dropout_op = nn.Dropout3d
norm_op = nn.InstanceNorm3d
else:
conv_op = nn.Conv2d
dropout_op = nn.Dropout2d
norm_op = nn.InstanceNorm2d
norm_op_kwargs = {'eps': 1e-5, 'affine': True}
dropout_op_kwargs = {'p': 0, 'inplace': True}
net_nonlin = nn.LeakyReLU
net_nonlin_kwargs = {'negative_slope': 1e-2, 'inplace': True}
self.network = Generic_UNet(self.num_input_channels, self.base_num_features, self.num_classes, net_numpool,
self.conv_per_stage, 2, conv_op, norm_op, norm_op_kwargs, dropout_op,
dropout_op_kwargs,
net_nonlin, net_nonlin_kwargs, False, False, lambda x: x, InitWeights_He(1e-2),
self.net_num_pool_op_kernel_sizes, self.net_conv_kernel_sizes, False, True, True)
self.network.inference_apply_nonlin = softmax_helper
if torch.cuda.is_available():
self.network.cuda()
def initialize_optimizer_and_scheduler(self):
assert self.network is not None, "self.initialize_network must be called first"
self.optimizer = torch.optim.Adam(self.network.parameters(), self.initial_lr, weight_decay=self.weight_decay,
amsgrad=True)
self.lr_scheduler = lr_scheduler.ReduceLROnPlateau(self.optimizer, mode='min', factor=0.2,
patience=self.lr_scheduler_patience,
verbose=True, threshold=self.lr_scheduler_eps,
threshold_mode="abs")
def plot_network_architecture(self):
try:
from batchgenerators.utilities.file_and_folder_operations import join
import hiddenlayer as hl
if torch.cuda.is_available():
g = hl.build_graph(self.network, torch.rand((1, self.num_input_channels, *self.patch_size)).cuda(),
transforms=None)
else:
g = hl.build_graph(self.network, torch.rand((1, self.num_input_channels, *self.patch_size)),
transforms=None)
g.save(join(self.output_folder, "network_architecture.pdf"))
del g
except Exception as e:
self.print_to_log_file("Unable to plot network architecture:")
self.print_to_log_file(e)
self.print_to_log_file("\nprinting the network instead:\n")
self.print_to_log_file(self.network)
self.print_to_log_file("\n")
finally:
if torch.cuda.is_available():
torch.cuda.empty_cache()
def run_training(self):
dct = OrderedDict()
for k in self.__dir__():
if not k.startswith("__"):
if not callable(getattr(self, k)):
dct[k] = str(getattr(self, k))
del dct['plans']
del dct['intensity_properties']
del dct['dataset']
del dct['dataset_tr']
del dct['dataset_val']
save_json(dct, join(self.output_folder, "debug.json"))
import shutil
shutil.copy(self.plans_file, join(self.output_folder_base, "plans.pkl"))
super(pixelCL_seg_Trainer, self).run_training()
def load_plans_file(self):
"""
This is what actually configures the entire experiment. The plans file is generated by experiment planning
:return:
"""
self.plans = load_pickle(self.plans_file)
def process_plans(self, plans):
if self.stage is None:
assert len(list(plans['plans_per_stage'].keys())) == 1, \
"If self.stage is None then there can be only one stage in the plans file. That seems to not be the " \
"case. Please specify which stage of the cascade must be trained"
self.stage = list(plans['plans_per_stage'].keys())[0]
self.plans = plans
stage_plans = self.plans['plans_per_stage'][self.stage]
#self.batch_size = stage_plans['batch_size']
#liuyiyao
self.batch_size = 8
self.net_pool_per_axis = stage_plans['num_pool_per_axis']
self.patch_size = np.array(stage_plans['patch_size']).astype(int)
self.do_dummy_2D_aug = stage_plans['do_dummy_2D_data_aug']
if 'pool_op_kernel_sizes' not in stage_plans.keys():
assert 'num_pool_per_axis' in stage_plans.keys()
self.print_to_log_file("WARNING! old plans file with missing pool_op_kernel_sizes. Attempting to fix it...")
self.net_num_pool_op_kernel_sizes = []
for i in range(max(self.net_pool_per_axis)):
curr = []
for j in self.net_pool_per_axis:
if (max(self.net_pool_per_axis) - j) <= i:
curr.append(2)
else:
curr.append(1)
self.net_num_pool_op_kernel_sizes.append(curr)
else:
self.net_num_pool_op_kernel_sizes = stage_plans['pool_op_kernel_sizes']
if 'conv_kernel_sizes' not in stage_plans.keys():
self.print_to_log_file("WARNING! old plans file with missing conv_kernel_sizes. Attempting to fix it...")
self.net_conv_kernel_sizes = [[3] * len(self.net_pool_per_axis)] * (max(self.net_pool_per_axis) + 1)
else:
self.net_conv_kernel_sizes = stage_plans['conv_kernel_sizes']
self.pad_all_sides = None # self.patch_size
self.intensity_properties = plans['dataset_properties']['intensityproperties']
self.normalization_schemes = plans['normalization_schemes']
self.base_num_features = plans['base_num_features']
self.num_input_channels = plans['num_modalities']
self.num_classes = plans['num_classes'] + 1 # background is no longer in num_classes
self.classes = plans['all_classes']
self.use_mask_for_norm = plans['use_mask_for_norm']
self.only_keep_largest_connected_component = plans['keep_only_largest_region']
self.min_region_size_per_class = plans['min_region_size_per_class']
self.min_size_per_class = None # DONT USE THIS. plans['min_size_per_class']
if plans.get('transpose_forward') is None or plans.get('transpose_backward') is None:
print("WARNING! You seem to have data that was preprocessed with a previous version of nnU-Net. "
"You should rerun preprocessing. We will proceed and assume that both transpose_foward "
"and transpose_backward are [0, 1, 2]. If that is not correct then weird things will happen!")
plans['transpose_forward'] = [0, 1, 2]
plans['transpose_backward'] = [0, 1, 2]
self.transpose_forward = plans['transpose_forward']
self.transpose_backward = plans['transpose_backward']
if len(self.patch_size) == 2:
self.threeD = False
elif len(self.patch_size) == 3:
self.threeD = True
else:
raise RuntimeError("invalid patch size in plans file: %s" % str(self.patch_size))
if "conv_per_stage" in plans.keys(): # this ha sbeen added to the plans only recently
self.conv_per_stage = plans['conv_per_stage']
else:
self.conv_per_stage = 2
def load_dataset(self):
self.dataset = load_dataset(self.folder_with_preprocessed_data)
def get_basic_generators(self):
self.load_dataset()
self.do_split()
if self.threeD:
dl_tr = DataLoader3D(self.dataset_tr, self.basic_generator_patch_size, self.patch_size, self.batch_size,
False, oversample_foreground_percent=self.oversample_foreground_percent,
pad_mode="constant", pad_sides=self.pad_all_sides, memmap_mode='r')
dl_val = DataLoader3D(self.dataset_val, self.patch_size, self.patch_size, self.batch_size, False,
oversample_foreground_percent=self.oversample_foreground_percent,
pad_mode="constant", pad_sides=self.pad_all_sides, memmap_mode='r')
else:
dl_tr = DataLoader2D(self.dataset_tr, self.basic_generator_patch_size, self.patch_size, self.batch_size,
oversample_foreground_percent=self.oversample_foreground_percent,
pad_mode="constant", pad_sides=self.pad_all_sides, memmap_mode='r')
dl_val = DataLoader2D(self.dataset_val, self.patch_size, self.patch_size, self.batch_size,
oversample_foreground_percent=self.oversample_foreground_percent,
pad_mode="constant", pad_sides=self.pad_all_sides, memmap_mode='r')
return dl_tr, dl_val
def preprocess_patient(self, input_files):
"""
Used to predict new unseen data. Not used for the preprocessing of the training/test data
:param input_files:
:return:
"""
from tuframework.training.model_restore import recursive_find_python_class
preprocessor_name = self.plans.get('preprocessor_name')
if preprocessor_name is None:
if self.threeD:
preprocessor_name = "GenericPreprocessor"
else:
preprocessor_name = "PreprocessorFor2D"
print("using preprocessor", preprocessor_name)
preprocessor_class = recursive_find_python_class([join(tuframework.__path__[0], "preprocessing")],
preprocessor_name,
current_module="tuframework.preprocessing")
assert preprocessor_class is not None, "Could not find preprocessor %s in tuframework.preprocessing" % \
preprocessor_name
preprocessor = preprocessor_class(self.normalization_schemes, self.use_mask_for_norm,
self.transpose_forward, self.intensity_properties)
d, s, properties = preprocessor.preprocess_test_case(input_files,
self.plans['plans_per_stage'][self.stage][
'current_spacing'])
return d, s, properties
def preprocess_predict_nifti(self, input_files: List[str], output_file: str = None,
softmax_ouput_file: str = None, mixed_precision: bool = True) -> None:
"""
Use this to predict new data
:param input_files:
:param output_file:
:param softmax_ouput_file:
:param mixed_precision:
:return:
"""
print("preprocessing...")
d, s, properties = self.preprocess_patient(input_files)
print("predicting...")
pred = self.predict_preprocessed_data_return_seg_and_softmax(d, do_mirroring=self.data_aug_params["do_mirror"],
mirror_axes=self.data_aug_params['mirror_axes'],
use_sliding_window=True, step_size=0.5,
use_gaussian=True, pad_border_mode='constant',
pad_kwargs={'constant_values': 0},
verbose=True, all_in_gpu=False,
mixed_precision=mixed_precision)[1]
pred = pred.transpose([0] + [i + 1 for i in self.transpose_backward])
if 'segmentation_export_params' in self.plans.keys():
force_separate_z = self.plans['segmentation_export_params']['force_separate_z']
interpolation_order = self.plans['segmentation_export_params']['interpolation_order']
interpolation_order_z = self.plans['segmentation_export_params']['interpolation_order_z']
else:
force_separate_z = None
interpolation_order = 1
interpolation_order_z = 0
print("resampling to original spacing and nifti export...")
save_segmentation_nifti_from_softmax(pred, output_file, properties, interpolation_order,
self.regions_class_order, None, None, softmax_ouput_file,
None, force_separate_z=force_separate_z,
interpolation_order_z=interpolation_order_z)
print("done")
def predict_preprocessed_data_return_seg_and_softmax(self, data: np.ndarray, do_mirroring: bool = True,
mirror_axes: Tuple[int] = None,
use_sliding_window: bool = True, step_size: float = 0.5,
use_gaussian: bool = True, pad_border_mode: str = 'constant',
pad_kwargs: dict = None, all_in_gpu: bool = False,
verbose: bool = True, mixed_precision: bool = True) -> Tuple[np.ndarray, np.ndarray]:
"""
:param data:
:param do_mirroring:
:param mirror_axes:
:param use_sliding_window:
:param step_size:
:param use_gaussian:
:param pad_border_mode:
:param pad_kwargs:
:param all_in_gpu:
:param verbose:
:return:
"""
if pad_border_mode == 'constant' and pad_kwargs is None:
pad_kwargs = {'constant_values': 0}
if do_mirroring and mirror_axes is None:
mirror_axes = self.data_aug_params['mirror_axes']
if do_mirroring:
assert self.data_aug_params["do_mirror"], "Cannot do mirroring as test time augmentation when training " \
"was done without mirroring"
valid = list((SegmentationNetwork, nn.DataParallel))
assert isinstance(self.network, tuple(valid))
current_mode = self.network.training
self.network.eval()
ret = self.network.predict_3D(data, do_mirroring=do_mirroring, mirror_axes=mirror_axes,
use_sliding_window=use_sliding_window, step_size=step_size,
patch_size=self.patch_size, regions_class_order=self.regions_class_order,
use_gaussian=use_gaussian, pad_border_mode=pad_border_mode,
pad_kwargs=pad_kwargs, all_in_gpu=all_in_gpu, verbose=verbose,
mixed_precision=mixed_precision)
self.network.train(current_mode)
return ret
def validate(self, do_mirroring: bool = True, use_sliding_window: bool = True, step_size: float = 0.5,
save_softmax: bool = True, use_gaussian: bool = True, overwrite: bool = True,
validation_folder_name: str = 'validation_raw', debug: bool = False, all_in_gpu: bool = False,
segmentation_export_kwargs: dict = None, run_postprocessing_on_folds: bool = True):
"""
if debug=True then the temporary files generated for postprocessing determination will be kept
"""
current_mode = self.network.training
self.network.eval()
assert self.was_initialized, "must initialize, ideally with checkpoint (or train first)"
if self.dataset_val is None:
self.load_dataset()
self.do_split()
if segmentation_export_kwargs is None:
if 'segmentation_export_params' in self.plans.keys():
force_separate_z = self.plans['segmentation_export_params']['force_separate_z']
interpolation_order = self.plans['segmentation_export_params']['interpolation_order']
interpolation_order_z = self.plans['segmentation_export_params']['interpolation_order_z']
else:
force_separate_z = None
interpolation_order = 1
interpolation_order_z = 0
else:
force_separate_z = segmentation_export_kwargs['force_separate_z']
interpolation_order = segmentation_export_kwargs['interpolation_order']
interpolation_order_z = segmentation_export_kwargs['interpolation_order_z']
# predictions as they come from the network go here
output_folder = join(self.output_folder, validation_folder_name)
if not os.path.isdir(output_folder):os.makedirs(output_folder)
# this is for debug purposes
my_input_args = {'do_mirroring': do_mirroring,
'use_sliding_window': use_sliding_window,
'step_size': step_size,
'save_softmax': save_softmax,
'use_gaussian': use_gaussian,
'overwrite': overwrite,
'validation_folder_name': validation_folder_name,
'debug': debug,
'all_in_gpu': all_in_gpu,
'segmentation_export_kwargs': segmentation_export_kwargs,
}
save_json(my_input_args, join(output_folder, "validation_args.json"))
if do_mirroring:
if not self.data_aug_params['do_mirror']:
raise RuntimeError("We did not train with mirroring so you cannot do inference with mirroring enabled")
mirror_axes = self.data_aug_params['mirror_axes']
else:
mirror_axes = ()
pred_gt_tuples = []
export_pool = Pool(default_num_threads)
results = []
for k in self.dataset_val.keys():
properties = load_pickle(self.dataset[k]['properties_file'])
fname = properties['list_of_data_files'][0].split("/")[-1][:-12]
if overwrite or (not isfile(join(output_folder, fname + ".nii.gz"))) or \
(save_softmax and not isfile(join(output_folder, fname + ".npz"))):
data = np.load(self.dataset[k]['data_file'])['data']
print(k, data.shape)
data[-1][data[-1] == -1] = 0
softmax_pred = self.predict_preprocessed_data_return_seg_and_softmax(data[:-1],
do_mirroring=do_mirroring,
mirror_axes=mirror_axes,
use_sliding_window=use_sliding_window,
step_size=step_size,
use_gaussian=use_gaussian,
all_in_gpu=all_in_gpu,
mixed_precision=self.fp16)[1]
softmax_pred = softmax_pred.transpose([0] + [i + 1 for i in self.transpose_backward])
if save_softmax:
softmax_fname = join(output_folder, fname + ".npz")
else:
softmax_fname = None
"""There is a problem with python process communication that prevents us from communicating obejcts
larger than 2 GB between processes (basically when the length of the pickle string that will be sent is
communicated by the multiprocessing.Pipe object then the placeholder (\%i I think) does not allow for long
enough strings (lol). This could be fixed by changing i to l (for long) but that would require manually
patching system python code. We circumvent that problem here by saving softmax_pred to a npy file that will
then be read (and finally deleted) by the Process. save_segmentation_nifti_from_softmax can take either
filename or np.ndarray and will handle this automatically"""
if np.prod(softmax_pred.shape) > (2e9 / 4 * 0.85): # *0.85 just to be save
np.save(join(output_folder, fname + ".npy"), softmax_pred)
softmax_pred = join(output_folder, fname + ".npy")
results.append(export_pool.starmap_async(save_segmentation_nifti_from_softmax,
((softmax_pred, join(output_folder, fname + ".nii.gz"),
properties, interpolation_order, self.regions_class_order,
None, None,
softmax_fname, None, force_separate_z,
interpolation_order_z),
)
)
)
pred_gt_tuples.append([join(output_folder, fname + ".nii.gz"),
join(self.gt_niftis_folder, fname + ".nii.gz")])
_ = [i.get() for i in results]
self.print_to_log_file("finished prediction")
# evaluate raw predictions
self.print_to_log_file("evaluation of raw predictions")
task = self.dataset_directory.split("/")[-1]
job_name = self.experiment_name
_ = aggregate_scores(pred_gt_tuples, labels=list(range(self.num_classes)),
json_output_file=join(output_folder, "summary.json"),
json_name=job_name + " val tiled %s" % (str(use_sliding_window)),
json_author="Fabian",
json_task=task, num_threads=default_num_threads)
if run_postprocessing_on_folds:
# in the old tuframework we would stop here. Now we add a postprocessing. This postprocessing can remove everything
# except the largest connected component for each class. To see if this improves results, we do this for all
# classes and then rerun the evaluation. Those classes for which this resulted in an improved dice score will
# have this applied during inference as well
self.print_to_log_file("determining postprocessing")
determine_postprocessing(self.output_folder, self.gt_niftis_folder, validation_folder_name,
final_subf_name=validation_folder_name + "_postprocessed", debug=debug)
# after this the final predictions for the vlaidation set can be found in validation_folder_name_base + "_postprocessed"
# They are always in that folder, even if no postprocessing as applied!
# detemining postprocesing on a per-fold basis may be OK for this fold but what if another fold finds another
# postprocesing to be better? In this case we need to consolidate. At the time the consolidation is going to be
# done we won't know what self.gt_niftis_folder was, so now we copy all the niftis into a separate folder to
# be used later
gt_nifti_folder = join(self.output_folder_base, "gt_niftis")
if not os.path.isdir(gt_nifti_folder):os.makedirs(gt_nifti_folder)
for f in subfiles(self.gt_niftis_folder, suffix=".nii.gz"):
success = False
attempts = 0
e = None
while not success and attempts < 10:
try:
shutil.copy(f, gt_nifti_folder)
success = True
except OSError as e:
attempts += 1
sleep(1)
if not success:
print("Could not copy gt nifti file %s into folder %s" % (f, gt_nifti_folder))
if e is not None:
raise e
self.network.train(current_mode)
def run_online_evaluation(self, output, target):
with torch.no_grad():
num_classes = output.shape[1]
output_softmax = softmax_helper(output)
output_seg = output_softmax.argmax(1)
target = target[:, 0]
axes = tuple(range(1, len(target.shape)))
tp_hard = torch.zeros((target.shape[0], num_classes - 1)).to(output_seg.device.index)
fp_hard = torch.zeros((target.shape[0], num_classes - 1)).to(output_seg.device.index)
fn_hard = torch.zeros((target.shape[0], num_classes - 1)).to(output_seg.device.index)
for c in range(1, num_classes):
tp_hard[:, c - 1] = sum_tensor((output_seg == c).float() * (target == c).float(), axes=axes)
fp_hard[:, c - 1] = sum_tensor((output_seg == c).float() * (target != c).float(), axes=axes)
fn_hard[:, c - 1] = sum_tensor((output_seg != c).float() * (target == c).float(), axes=axes)
tp_hard = tp_hard.sum(0, keepdim=False).detach().cpu().numpy()
fp_hard = fp_hard.sum(0, keepdim=False).detach().cpu().numpy()
fn_hard = fn_hard.sum(0, keepdim=False).detach().cpu().numpy()
self.online_eval_foreground_dc.append(list((2 * tp_hard) / (2 * tp_hard + fp_hard + fn_hard + 1e-8)))
self.online_eval_tp.append(list(tp_hard))
self.online_eval_fp.append(list(fp_hard))
self.online_eval_fn.append(list(fn_hard))
def finish_online_evaluation(self):
self.online_eval_tp = np.sum(self.online_eval_tp, 0)
self.online_eval_fp = np.sum(self.online_eval_fp, 0)
self.online_eval_fn = np.sum(self.online_eval_fn, 0)
global_dc_per_class = [i for i in [2 * i / (2 * i + j + k) for i, j, k in
zip(self.online_eval_tp, self.online_eval_fp, self.online_eval_fn)]
if not np.isnan(i)]
self.all_val_eval_metrics.append(np.mean(global_dc_per_class))
self.print_to_log_file("Average global foreground Dice:", str(global_dc_per_class))
self.print_to_log_file("(interpret this as an estimate for the Dice of the different classes. This is not "
"exact.)")
self.online_eval_foreground_dc = []
self.online_eval_tp = []
self.online_eval_fp = []
self.online_eval_fn = []
def save_checkpoint(self, fname, save_optimizer=True):
super(pixelCL_seg_Trainer, self).save_checkpoint(fname, save_optimizer)
info = OrderedDict()
info['init'] = self.init_args
info['name'] = self.__class__.__name__
info['class'] = str(self.__class__)
info['plans'] = self.plans
write_pickle(info, fname + ".pkl")
