Ejemplo n.º 1
0
def runMeme(infile, outfile):
    '''run MEME to find motifs.

    In order to increase the signal/noise ratio, MEME is not run on
    all intervals but only the top 10% of intervals (peakval) are
    used.  Also, only the segment of 200 bp around the peak is used
    and not the complete interval.

    * Softmasked sequence is converted to hardmasked
      sequence to avoid the detection of spurious motifs.

    * Sequence is run through dustmasker

    '''
    PipelineMotifs.runMEMEOnSequences(infile, outfile)
Ejemplo n.º 2
0
def runDiscMEME(infiles, outfile):
    ''' Run MEME with PSP file, therefore making it 
    discrimenative'''

    psp, fasta = infiles
    PipelineMotifs.runMEMEOnSequences(fasta, outfile, psp=psp)