def main(args):
np.random.seed(args.seed)
# CPU only instead of GPU
if args.cpu_only:
logging.info('Setting env for CPU-only mode...')
os.environ["CUDA_DEVICE_ORDER"] = "PCI_BUS_ID" # see issue #152
os.environ["CUDA_VISIBLE_DEVICES"] = '-1'
# Load and process data
# Provide objective to load
recall_0 = Utils.class_recall(0)
recall_1 = Utils.class_recall(1)
custom_obj = {'metr': recall_0}
logging.info('Loading model...')
## pkl
logging.info(' Loading mstd...')
F = os.path.join(args.model_path, args.mstd_name)
if not os.path.exists(F):
msg = 'Model file not available at data-path: {}'
raise IOError(msg.format(F))
with open(F, 'rb') as mstd:
mean_tr, std_tr = pickle.load(mstd)
## h5
logging.info(' Loading h5...')
F = os.path.join(args.model_path, args.model_name)
if not os.path.exists(F):
msg = 'Model file not available at data-path: {}'
raise IOError(msg.format(F))
model = load_model(F, custom_objects=custom_obj)
# outdir
if not os.path.exists(args.save_path):
os.makedirs(args.save_path)
logging.info('Loading features...')
x, y, i2n = Utils.load_features_nogt(args.feature_file_table,
force_overwrite=args.force_overwrite,
pickle_only=args.pickle_only,
n_procs=args.n_procs)
logging.info('Loaded {} contigs'.format(len(set(i2n.values()))))
n2i = Utils.reverse_dict(i2n)
x = [xi for xmeta in x for xi in xmeta]
y = np.concatenate(y)
logging.info('Running model generator...')
dataGen = Models.Generator(x,
y,
batch_size=64,
shuffle=False,
norm_raw=0,
mean_tr=mean_tr,
std_tr=std_tr)
logging.info('Computing predictions...')
scores = Utils.compute_predictions(n2i, dataGen, model, args.save_path,
args.save_name)
def main(args):
np.random.seed(12)
# Build model
config = Config(args)
deepmased = Models.deepmased(config)
deepmased.print_summary()
if not os.path.exists(args.save_path):
os.makedirs(args.save_path)
save_path = args.save_path
# Load and process data
logging.info('Loading data...')
x, y = Utils.load_features_tr(args.data_path,
max_len=args.max_len,
standard=args.standard,
mode = config.mode,
pickle_only=args.pickle_only)
if args.n_folds == -1:
# Append elements in x
x = [item for sl in x for item in sl]
y = np.concatenate(y)
if args.n_folds > -1:
if os.path.exists(os.path.join(save_path, str(args.n_folds - 1) + '_model.h5')):
exit()
ap_scores = []
for val_idx in range(args.n_folds):
x_tr, x_val, y_tr, y_val = Utils.kfold(x, y, val_idx, k=args.n_folds)
deepmased = Models.deepmased(config)
#Construct generator
dataGen = Models.Generator(x_tr, y_tr, args.max_len,
batch_size=64, norm_raw=bool(args.norm_raw))
# Init validation generator and
dataGen_val = Models.Generator(x_val, y_val, args.max_len, batch_size=64,
shuffle=False, norm_raw=bool(args.norm_raw),
mean_tr=dataGen.mean, std_tr=dataGen.std)
#Train model
tb_logs = keras.callbacks.TensorBoard(log_dir=os.path.join(save_path, 'logs'),
histogram_freq=0,
write_graph=True, write_images=True)
logging.info('Training network...')
if config.mode in ['chimera', 'extensive']:
w_one = int(len(np.where(y_tr == 0)[0]) / len(np.where(y_tr == 1)[0]))
class_weight = {0 : 1 , 1: w_one}
deepmased.net.fit_generator(generator=dataGen,
validation_data=dataGen_val,
epochs=args.n_epochs,
use_multiprocessing=True,
verbose=2,
callbacks=[tb_logs, deepmased.reduce_lr])
elif config.mode == 'edit':
st = StandardScaler()
y_tr = st.fit_transform(y_tr)
y_te = st.transform(y_te)
deepmased.net.fit(x_tr, y_tr, validation_data=(x_te, y_te),
epochs=args.n_epochs,
callbacks=[tb_logs, deepmased.reduce_lr])
logging.info('Computing AUC scores...')
scores_val = deepmased.predict_generator(dataGen_val)
ap_scores.append(average_precision_score(y_val[0 : scores_val.size], scores_val))
deepmased.save(os.path.join(save_path, str(val_idx) + '_model.h5'))
with open(os.path.join(save_path, 'scores.pkl'), 'wb') as f:
pickle.dump(ap_scores, f)
else:
dataGen = Models.Generator(x, y, args.max_len, batch_size=64,
norm_raw=bool(args.norm_raw))
deepmased = Models.deepmased(config)
tb_logs = keras.callbacks.TensorBoard(log_dir=os.path.join(save_path, 'logs_final'),
histogram_freq=0,
write_graph=True, write_images=True)
logging.info('Training network...')
if config.mode in ['chimera', 'extensive']:
w_one = int(len(np.where(y == 0)[0]) / len(np.where(y == 1)[0]))
class_weight = {0 : 1 , 1: w_one}
deepmased.net.fit_generator(generator=dataGen,
epochs=args.n_epochs,
use_multiprocessing=True,
verbose=2,
callbacks=[tb_logs, deepmased.reduce_lr])
logging.info('Saving trained model...')
outfile = os.path.join(save_path, 'final_model.h5')
deepmased.save(outfile)
logging.info(' File written: {}'.format(outfile))
outfile = os.path.join(save_path, 'mean_std_final_model.pkl')
with open(outfile, 'wb') as f:
pickle.dump([dataGen.mean, dataGen.std], f)
logging.info(' File written: {}'.format(outfile))
def main(args):
"""Main interface
"""
np.random.seed(12)
save_plot = args.save_plot
if save_plot is None:
save_plot = args.save_path
# Load and process data
# Provide objective to load
recall_0 = Utils.class_recall(0)
recall_1 = Utils.class_recall(1)
custom_obj = {'metr': recall_0}
path_to_models = os.listdir(args.save_path)
auc = []
for model_path in path_to_models:
if not os.path.exists(
(os.path.join(args.save_path, model_path, 'final_model.h5'))):
continue
if not os.path.exists(
os.path.join(args.save_path, model_path, 'predictions')):
os.makedirs(os.path.join(args.save_path, model_path,
'predictions'))
if not os.path.exists(
os.path.join(args.save_path, model_path, 'predictions',
args.data_path.split('/')[-1])):
os.makedirs(
os.path.join(args.save_path, model_path, 'predictions',
args.data_path.split('/')[-1]))
F = os.path.join(args.save_path, model_path,
'mean_std_final_model.pkl')
with open(F, 'rb') as mstd:
mean_tr, std_tr = pickle.load(mstd)
model = load_model(os.path.join(args.save_path, model_path,
'final_model.h5'),
custom_objects=custom_obj)
tech = args.technology
logging.info('Loading data...')
if args.is_synthetic == 1:
x, y, i2n = Utils.load_features(args.data_path,
max_len=args.max_len,
mode=args.mode,
technology=tech)
else:
x, y, i2n = Utils.load_features_nogt(args.data_path,
max_len=args.max_len,
mode=args.mode)
logging.info('Loaded {} contigs...'.format(len(set(i2n.values()))))
n2i = Utils.reverse_dict(i2n)
x = [xi for xmeta in x for xi in xmeta]
y = np.concatenate(y)
dataGen = Models.Generator(x,
y,
args.max_len,
batch_size=64,
shuffle=False,
norm_raw=bool(args.norm_raw),
mean_tr=mean_tr,
std_tr=std_tr)
loggin.info('Computing predictions for {}...'.format(tech))
scores = compute_predictions(y, n2i)
outfile = os.path.join(args.save_path, model_path, 'predictions',
args.data_path.split('/')[-1], tech + '.pkl')
with open(outfile, 'wb') as spred:
pickle.dump(scores, spred)
logging.info('File written: {}'.format(outfile))
def main(args):
"""Main interface
"""
# init
np.random.seed(args.seed)
## where to save the plot
save_plot = args.save_plot
if save_plot is None:
save_plot = args.save_path
# Load and process data
# Provide objective to load
logging.info('Loading data...')
recall_0 = Utils.class_recall(0)
recall_1 = Utils.class_recall(1)
custom_obj = {'metr': recall_0}
h5_file = os.path.join(args.model_path, args.model_name)
if not os.path.exists(h5_file):
msg = 'Cannot find {} file in {}'
raise IOError(msg.format(args.model_name, args.model_path))
logging.info('Loading model: {}'.format(h5_file))
model = load_model(h5_file, custom_objects=custom_obj)
# model pkl
pkl_file = os.path.join(args.model_path, args.mstd_name)
logging.info('Loading file: {}'.format(pkl_file))
with open(pkl_file, 'rb') as mstd:
mean_tr, std_tr = pickle.load(mstd)
# loading features
if args.is_synthetic == 1:
logging.info('Loading synthetic features')
x, y, i2n = Utils.load_features(args.feature_file_table,
max_len=args.max_len,
technology=args.technology,
force_overwrite=args.force_overwrite,
n_procs=args.n_procs)
else:
logging.info('Loading non-synthetic features')
x, y, i2n = Utils.load_features_nogt(
args.feature_file_table,
max_len=args.max_len,
force_overwrite=args.force_overwrite,
n_procs=args.n_procs)
logging.info('Loaded {} contigs'.format(len(set(i2n.values()))))
n2i = Utils.reverse_dict(i2n)
x = [xi for xmeta in x for xi in xmeta]
y = np.concatenate(y)
logging.info('Running model generator...')
dataGen = Models.Generator(x,
y,
args.max_len,
batch_size=64,
shuffle=False,
norm_raw=bool(args.norm_raw),
mean_tr=mean_tr,
std_tr=std_tr)
logging.info('Computing predictions for {}...'.format(args.technology))
scores = Utils.compute_predictions_y_known(y, n2i, model, dataGen)
outfile = os.path.join(
args.save_path, '_'.join([args.save_name, args.technology + '.pkl']))
with open(outfile, 'wb') as spred:
pickle.dump(scores, spred)
logging.info('File written: {}'.format(outfile))
def main(args):
# init
np.random.seed(args.seed)
if not os.path.exists(args.save_path):
os.makedirs(args.save_path)
save_path = args.save_path
# Build model
config = Config(args)
if not args.pickle_only:
logging.info('Building model')
deepmased = Models.deepmased(config)
deepmased.print_summary()
# Load and process data
x, y = Utils.load_features_tr(args.feature_file_table,
max_len=args.max_len,
technology = args.technology,
pickle_only = args.pickle_only,
force_overwrite = args.force_overwrite,
n_procs = args.n_procs)
# kfold cross validation
if args.n_folds >= 0:
logging.info('Running kfold cross validation. n-folds: {}'.format(args.n_folds))
outfile_h5 = os.path.join(save_path, str(args.n_folds - 1) + '_model.h5')
if os.path.exists(outfile_h5) and args.force_overwrite is False:
msg = 'Output already exists ({}). Use --force-overwrite to overwrite the file'
raise IOError(msg.format(outfile_h5))
# iter over folds
ap_scores = []
for val_idx in range(args.n_folds):
logging.info('Fold {}: Constructing model...'.format(val_idx))
x_tr, x_val, y_tr, y_val = Utils.kfold(x, y, val_idx, k=args.n_folds)
deepmased = Models.deepmased(config)
#Construct generator
dataGen = Models.Generator(x_tr, y_tr, args.max_len,
batch_size=64, norm_raw=bool(args.norm_raw))
# Init validation generator and
dataGen_val = Models.Generator(x_val, y_val, args.max_len, batch_size=64,
shuffle=False, norm_raw=bool(args.norm_raw),
mean_tr=dataGen.mean, std_tr=dataGen.std)
#Train model
tb_logs = keras.callbacks.TensorBoard(log_dir=os.path.join(save_path, 'logs'),
histogram_freq=0,
write_graph=True, write_images=True)
logging.info('Fold {}: Training network...'.format(val_idx))
## binary classification (extensive misassembly)
try:
w_one = int(len(np.where(y_tr == 0)[0]) / len(np.where(y_tr == 1)[0]))
except ZeroDivisionError:
logging.warning(' No misassemblies present!')
w_one = 0
class_weight = {0 : 1 , 1: w_one}
deepmased.net.fit_generator(generator=dataGen,
validation_data=dataGen_val,
epochs=args.n_epochs,
use_multiprocessing=args.n_procs > 1,
workers=args.n_procs,
verbose=2,
callbacks=[tb_logs, deepmased.reduce_lr])
# AUC scores
logging.info('Fold {}: Computing AUC scores...'.format(val_idx))
scores_val = deepmased.predict_generator(dataGen_val)
ap_scores.append(average_precision_score(y_val[0 : scores_val.size], scores_val))
# Saving data
outfile_h5_fold = os.path.join(save_path, str(val_idx) + '_model.h5')
deepmased.save(outfile_h5_fold)
logging.info('Fold {}: File written: {}'.format(val_idx, outfile_h5_fold))
outfile_pkl_fold = os.path.join(save_path, 'scores.pkl')
with open(outfile_pkl_fold, 'wb') as f:
pickle.dump(ap_scores, f)
logging.info('Fold {}: File written: {}'.format(val_idx, outfile_pkl_fold))
else:
# Skip kfold and simply pool all the data for training
## all elements in x and y are combined
logging.info('NOTE: Training on all pooled data!')
x = [item for sl in x for item in sl]
y = np.concatenate(y)
# #downsample to half
# import random
# dwnsample = np.array(random.sample(range(len(y)), int(len(y)/2)))
# x = np.array(x)[dwnsample]
# y = np.array(y)[dwnsample]
logging.info('Constructing model...')
dataGen = Models.Generator(x, y, args.max_len, batch_size=64,
norm_raw=bool(args.norm_raw))
deepmased = Models.deepmased(config)
tb_logs = keras.callbacks.TensorBoard(log_dir=os.path.join(save_path, 'logs_final'),
histogram_freq=0,
write_graph=True, write_images=True)
logging.info('Training network...')
deepmased.net.fit_generator(generator=dataGen,
epochs=args.n_epochs,
use_multiprocessing=args.n_procs > 1,
workers=args.n_procs,
verbose=2,
callbacks=[tb_logs, deepmased.reduce_lr])
logging.info('Saving trained model...')
x = [args.save_name, args.technology, 'model.h5']
outfile = os.path.join(save_path, '_'.join(x))
deepmased.save(outfile)
logging.info(' File written: {}'.format(outfile))
x = [args.save_name, args.technology, 'mean_std.pkl']
outfile = os.path.join(save_path, '_'.join(x))
with open(outfile, 'wb') as f:
pickle.dump([dataGen.mean, dataGen.std], f)
logging.info(' File written: {}'.format(outfile))