def updateContext(fN, fF, wigDir, chrom, strand, switchStrand = False):
        
    NX = Nexus(fN, fF)
    NX.load(['tcc', 'context'])
    
    if switchStrand:
        strand = str(-int(strand))
    else:
        strand = str(strand)
    
    print 'loading wig'
    coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'context') 
    print 'done loading'

    ds = bioLibCG.dominantSpotter(['C_EXON', 'C_3UTR', 'C_5UTR', 'NC_EXON', 'NC_3UTR', 'NC_5UTR', 'C_INTRON', 'NC_INTRON', 'INTER']) 


    while NX.nextID():

        oChrom, oStrand, start, end = bioLibCG.tccSplit(NX.tcc)
        
        #deg wigs is AS to actual clipping site
        if switchStrand:
            oStrand = str(-int(strand))
        else:
            oStrand = str(oStrand)

        if oChrom == chrom and oStrand == strand:

            contexts = coord_contexts.get(start, 'INTER').split(',')
            NX.context = ds.spotItem(contexts)

    
    NX.save()
Example #2
0
def updateContext(oFN, wigDir, chrom, strand, rn = None, tn = None):

        oNX = cgNexusFlat.Nexus(oFN, degPeak.degPeak)
        oNX.load(['context', 'tcc'], [rn, tn])

        print 'loading wig'
        coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'context') 
        print 'done loading'

        ds = bioLibCG.dominantSpotter(['C_EXON', 'C_3UTR', 'C_5UTR', 'NC_EXON', 'NC_3UTR', 'NC_5UTR', 'C_INTRON', 'NC_INTRON', 'INTER']) 


        for oID in oNX.tcc:

                oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])
                
                #deg wigs is AS to actual clipping site
                if oStrand == '1':
                        oStrand = '-1'
                else:
                        oStrand = '1'
        
                if oChrom == chrom and oStrand == strand:

                        contexts = coord_contexts.get(start, 'INTER').split(',')
                        oNX.context[oID] = ds.spotItem(contexts)
        
        oNX.save()
Example #3
0
def updateContext(oFN, wigDir, chrom, strand, rn=None, tn=None):

    oNX = cgNexusFlat.Nexus(oFN, degPeak.degPeak)
    oNX.load(['context', 'tcc'], [rn, tn])

    print 'loading wig'
    coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand,
                                                'context')
    print 'done loading'

    ds = bioLibCG.dominantSpotter([
        'C_EXON', 'C_3UTR', 'C_5UTR', 'NC_EXON', 'NC_3UTR', 'NC_5UTR',
        'C_INTRON', 'NC_INTRON', 'INTER'
    ])

    for oID in oNX.tcc:

        oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])

        #deg wigs is AS to actual clipping site
        if oStrand == '1':
            oStrand = '-1'
        else:
            oStrand = '1'

        if oChrom == chrom and oStrand == strand:

            contexts = coord_contexts.get(start, 'INTER').split(',')
            oNX.context[oID] = ds.spotItem(contexts)

    oNX.save()
Example #4
0
def updateContext(oFN, wigDir, chrom, strand, switchStrand = False):
        
        oNX = cgNexusFlat.Nexus(oFN, cgDegPeak.Peak)
        oNX.load(['tcc', 'context'])
        
        if switchStrand:
            strand = str(-int(strand))
        else:
            strand = str(strand)
        
        print 'loading wig'
        coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'context') 
        print 'done loading'

        ds = bioLibCG.dominantSpotter(['C_EXON', 'C_3UTR', 'C_5UTR', 'NC_EXON', 'NC_3UTR', 'NC_5UTR', 'C_INTRON', 'NC_INTRON', 'INTER']) 


        for oID in oNX.tcc:

                oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])
                
                #deg wigs is AS to actual clipping site
                if switchStrand:
                    oStrand = str(-int(strand))
                else:
                    oStrand = str(oStrand)
        
                if oChrom == chrom and oStrand == strand:

                        contexts = coord_contexts.get(start, 'INTER').split(',')
                        oNX.context[oID] = ds.spotItem(contexts)

        
        oNX.save()
def updateIContext(oFN, wigDir, chrom, strand, rn = None, tn = None):
        
        oNX = cgNexusFlat.Nexus(oFN, cgDegPeak.Peak)
        oNX.load(['tcc', 'iContexts'], [rn, tn])
        
         
        if strand == '1':
                strand = '-1'
        else:
                strand = '1'
        
        print 'loading wig'
        coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'iContext') 
        print 'done loading'

        for oID in oNX.tcc:

                oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])
                
                #deg wigs is AS to actual clipping site
                if oStrand == '1':
                        oStrand = '-1'
                else:
                        oStrand = '1'
        
                if oChrom == chrom and oStrand == strand:

                        contexts = coord_contexts.get(start, '-1').split(',')
                        contexts = [int(x) for x in contexts]

                        oNX.iContexts[oID] = contexts

        
        oNX.save()
Example #6
0
def updateTypeAlignment(oFN, wigDir, chrom, strand, rn = None, tn = None):
        '''This is for ALIGNMENTS...NOT DEG PEAKS!'''

        oNX = cgNexusFlat.Nexus(oFN, cgAlignmentFlat.cgAlignment)
        oNX.load(['tTcc', 'type'], [rn, tn])
        
                
        if strand == '1':
                strand = '-1'
        else:
                strand = '1'
        
        print 'loading wig'
        coord_types = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'tType') 
        print 'done loading'
        
        domOrder = ['microRNA_noncoding',
        'lincRNA_noncoding',
        'longNC_noncoding',
        'miRNA_pseudogene_noncoding',
        'Mt_rRNA_noncoding',
        'Mt_tRNA_noncoding',
        'Mt_tRNA_pseudogene_noncoding',
        'rRNA_noncoding',
        'rRNA_pseudogene_noncoding',
        'scRNA_pseudogene_noncoding',
        'snoRNA_noncoding',
        'snoRNA_pseudogene_noncoding',
        'snRNA_noncoding',
        'snRNA_pseudogene_noncoding',
        'tRNA_pseudogene_noncoding',
        'pseudogene_noncoding',
        'protein_coding',
        'None']
        
        ds = bioLibCG.dominantSpotter(domOrder)


        for oID in oNX.tTcc:

                oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tTcc[oID])
                
                #deg wigs is AS to actual clipping site
                if oStrand == '1':
                        oStrand = '-1'
                else:
                        oStrand = '1'
                
                if oChrom == chrom and oStrand == strand:

                        tranTypes = coord_types.get(start, 'None').split(',')
                        types = [x.split(':')[1] if x != 'None' else 'None' for x in tranTypes]
                        types = list(set(types))
                        oNX.type[oID] = ds.spotItem(types)

        
        oNX.save()
def updateType(oFN, wigDir, chrom, strand, rn = None, tn = None):
        
        oNX = cgNexusFlat.Nexus(oFN, cgOriginRNAFlat.OriginRNA)
        oNX.load(['tcc', 'transcriptType', 'transcriptTypes'], [rn, tn])
        
                
        print 'loading wig'
        coord_types = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'tType') 
        print 'done loading'
        

        domOrder = ['microRNA_noncoding',
        'lincRNA_noncoding',
        'longNC_noncoding',
        'miRNA_pseudogene_noncoding',
        'Mt_rRNA_noncoding',
        'Mt_tRNA_noncoding',
        'Mt_tRNA_pseudogene_noncoding',
        'rRNA_noncoding',
        'rRNA_pseudogene_noncoding',
        'scRNA_pseudogene_noncoding',
        'snoRNA_noncoding',
        'snoRNA_pseudogene_noncoding',
        'snRNA_noncoding',
        'snRNA_pseudogene_noncoding',
        'tRNA_pseudogene_noncoding',
        'pseudogene_noncoding',
        'protein_coding',
        'None']


        ds = cg.dominantSpotter(domOrder)


        for oID in oNX.tcc:

                oChrom, oStrand, start, end = cg.tccSplit(oNX.tcc[oID])
                if oChrom == chrom and oStrand == strand:

                        tranTypes = coord_types.get(start, 'None').split(',')
                        types = [x.split(':')[1] if x != 'None' else 'None' for x in tranTypes]

                        types = list(set(types))
                        oNX.transcriptTypes[oID] = types 
                        oNX.transcriptType[oID] = ds.spotItem(types)

        
        oNX.save()
Example #8
0
def updateType(oFN, wigDir, chrom, strand, rn=None, tn=None):

    oNX = cgNexusFlat.Nexus(oFN, cgDegPeak.Peak)
    oNX.load(['tcc', 'type'], [rn, tn])

    if strand == '1':
        strand = '-1'
    else:
        strand = '1'

    print 'loading wig'
    coord_types = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'tType')
    print 'done loading'

    domOrder = [
        'protein_coding', 'miRNA', 'rRNA', 'snoRNA', 'snRNA', 'lincRNA',
        'longNC', 'misc_RNA', 'Mt_rRNA', 'Mt_tRNA', 'misc_RNA_pseudogene',
        'Mt_tRNA_pseudogene', 'polymorphic_pseudogene', 'processed_transcript',
        'miRNA_pseudogene', 'rRNA_pseudogene', 'scRNA_pseudogene',
        'snoRNA_pseudogene', 'snRNA_pseudogene', 'tRNA_pseudogene',
        'pseudogene', 'TR_C_gene', 'TR_J_gene', 'TR_V_gene', 'TR_V_pseudogene',
        'IG_C_gene', 'IG_C_pseudogene', 'IG_D_gene', 'IG_J_gene',
        'IG_J_pseudogene', 'IG_V_gene', 'IG_V_pseudogene', 'unknown', 'None'
    ]

    ds = bioLibCG.dominantSpotter(domOrder)

    for oID in oNX.tcc:

        oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])

        #deg wigs is AS to actual clipping site
        if oStrand == '1':
            oStrand = '-1'
        else:
            oStrand = '1'

        if oChrom == chrom and oStrand == strand:

            tranTypes = coord_types.get(start, 'None').split(',')
            print tranTypes
            types = [
                x.split(':')[1] if x != 'None' else ['None'] for x in tranTypes
            ]

            oNX.type = oNX.transcriptType = ds.spotItem(types)

    oNX.save()
def updateType(oFN, wigDir, chrom, strand, rn = None, tn = None):
        
        oNX = cgNexusFlat.Nexus(oFN, cgOriginRNAFlat.OriginRNA)
        oNX.load(['tcc', 'transcriptType', 'transcriptTypes'], [rn, tn])
        
                
        print 'loading wig'
        coord_types = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'tType') 
        print 'done loading'
        

        domOrder = ['microRNA_noncoding',
        'lincRNA_noncoding',
        'longNC_noncoding',
        'miRNA_pseudogene_noncoding',
        'Mt_rRNA_noncoding',
        'Mt_tRNA_noncoding',
        'Mt_tRNA_pseudogene_noncoding',
        'rRNA_noncoding',
        'rRNA_pseudogene_noncoding',
        'scRNA_pseudogene_noncoding',
        'snoRNA_noncoding',
        'snoRNA_pseudogene_noncoding',
        'snRNA_noncoding',
        'snRNA_pseudogene_noncoding',
        'tRNA_pseudogene_noncoding',
        'pseudogene_noncoding',
        'protein_coding',
        'None']


        ds = cg.dominantSpotter(domOrder)


        for oID in oNX.tcc:

                oChrom, oStrand, start, end = cg.tccSplit(oNX.tcc[oID])
                if oChrom == chrom and oStrand == strand:

                        tranTypes = coord_types.get(start, 'None').split(',')
                        types = [x.split(':')[1] if x != 'None' else 'None' for x in tranTypes]

                        types = list(set(types))
                        oNX.transcriptTypes[oID] = types 
                        oNX.transcriptType[oID] = ds.spotItem(types)

        
        oNX.save()
Example #10
0
def updateTypeAlignment(oFN, wigDir, chrom, strand, rn=None, tn=None):
    '''This is for ALIGNMENTS...NOT DEG PEAKS!'''

    oNX = cgNexusFlat.Nexus(oFN, cgAlignmentFlat.cgAlignment)
    oNX.load(['tTcc', 'type'], [rn, tn])

    if strand == '1':
        strand = '-1'
    else:
        strand = '1'

    print 'loading wig'
    coord_types = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'tType')
    print 'done loading'

    domOrder = [
        'microRNA_noncoding', 'lincRNA_noncoding', 'longNC_noncoding',
        'miRNA_pseudogene_noncoding', 'Mt_rRNA_noncoding', 'Mt_tRNA_noncoding',
        'Mt_tRNA_pseudogene_noncoding', 'rRNA_noncoding',
        'rRNA_pseudogene_noncoding', 'scRNA_pseudogene_noncoding',
        'snoRNA_noncoding', 'snoRNA_pseudogene_noncoding', 'snRNA_noncoding',
        'snRNA_pseudogene_noncoding', 'tRNA_pseudogene_noncoding',
        'pseudogene_noncoding', 'protein_coding', 'None'
    ]

    ds = bioLibCG.dominantSpotter(domOrder)

    for oID in oNX.tTcc:

        oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tTcc[oID])

        #deg wigs is AS to actual clipping site
        if oStrand == '1':
            oStrand = '-1'
        else:
            oStrand = '1'

        if oChrom == chrom and oStrand == strand:

            tranTypes = coord_types.get(start, 'None').split(',')
            types = [
                x.split(':')[1] if x != 'None' else 'None' for x in tranTypes
            ]
            types = list(set(types))
            oNX.type[oID] = ds.spotItem(types)

    oNX.save()
Example #11
0
def updateType(oFN, wigDir, chrom, strand, rn = None, tn = None):

        oNX = cgNexusFlat.Nexus(oFN, cgDegPeak.Peak)
        oNX.load(['tcc', 'type'], [rn, tn])
        
                
        if strand == '1':
                strand = '-1'
        else:
                strand = '1'
        
        print 'loading wig'
        coord_types = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'tType') 
        print 'done loading'
        
        domOrder = ['protein_coding', 'miRNA', 'rRNA', 'snoRNA', 'snRNA', 'lincRNA', 'longNC', 'misc_RNA',
                    'Mt_rRNA', 'Mt_tRNA', 'misc_RNA_pseudogene', 'Mt_tRNA_pseudogene', 'polymorphic_pseudogene',
                    'processed_transcript', 'miRNA_pseudogene', 'rRNA_pseudogene', 'scRNA_pseudogene',
                    'snoRNA_pseudogene', 'snRNA_pseudogene', 'tRNA_pseudogene', 'pseudogene', 'TR_C_gene',
                    'TR_J_gene', 'TR_V_gene', 'TR_V_pseudogene', 'IG_C_gene', 'IG_C_pseudogene', 'IG_D_gene',
                    'IG_J_gene', 'IG_J_pseudogene', 'IG_V_gene', 'IG_V_pseudogene', 'unknown', 'None']
        
        ds = bioLibCG.dominantSpotter(domOrder)


        for oID in oNX.tcc:

                oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])
                
                #deg wigs is AS to actual clipping site
                if oStrand == '1':
                        oStrand = '-1'
                else:
                        oStrand = '1'
                
                if oChrom == chrom and oStrand == strand:

                        tranTypes = coord_types.get(start, 'None').split(',')
                        print tranTypes
                        types = [x.split(':')[1] if x != 'None' else ['None'] for x in tranTypes]

                        oNX.type = oNX.transcriptType = ds.spotItem(types)

        
        oNX.save()
def updateContext(oFN, wigDir, chrom, strand, rn = None, tn = None):
        
        oNX = cgNexusFlat.Nexus(oFN, cgOriginRNAFlat.OriginRNA)
        oNX.load(['tcc', 'context'], [rn, tn])
        
                
        print 'loading wig'
        coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'context') 
        print 'done loading'

        ds = cg.dominantSpotter(['C_EXON', 'C_3UTR', 'C_5UTR', 'NC_EXON', 'NC_3UTR', 'NC_5UTR', 'C_INTRON', 'NC_INTRON', 'INTER']) 


        for oID in oNX.tcc:

                oChrom, oStrand, start, end = cg.tccSplit(oNX.tcc[oID])
                if oChrom == chrom and oStrand == strand:

                        contexts = coord_contexts.get(start, 'INTER').split(',')
                        oNX.context[oID] = ds.spotItem(contexts)

        
        oNX.save()
Example #13
0
def updateContext(oFN, wigDir, chrom, strand, rn = None, tn = None):
        
        oNX = cgNexusFlat.Nexus(oFN, cgOriginRNAFlat.OriginRNA)
        oNX.load(['tcc', 'context'], [rn, tn])
        
                
        print 'loading wig'
        coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand, 'context') 
        print 'done loading'

        ds = cg.dominantSpotter(['C_EXON', 'C_3UTR', 'C_5UTR', 'NC_EXON', 'NC_3UTR', 'NC_5UTR', 'C_INTRON', 'NC_INTRON', 'INTER']) 


        for oID in oNX.tcc:

                oChrom, oStrand, start, end = cg.tccSplit(oNX.tcc[oID])
                if oChrom == chrom and oStrand == strand:

                        contexts = coord_contexts.get(start, 'INTER').split(',')
                        oNX.context[oID] = ds.spotItem(contexts)

        
        oNX.save()
Example #14
0
def updateIContext(oFN, wigDir, chrom, strand, switchStrand=True):

    strand = str(strand)

    oNX = cgNexusFlat.Nexus(oFN, cgDegPeak.Peak)
    oNX.load(['tcc', 'iContexts'])

    if switchStrand:
        if strand == '1':
            strand = '-1'
        else:
            strand = '1'

    print 'loading wig'
    coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand,
                                                'iContext')
    print 'done loading'

    for oID in oNX.tcc:

        oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])

        #deg wigs is AS to actual clipping site
        if switchStrand:
            if oStrand == '1':
                oStrand = '-1'
            else:
                oStrand = '1'

        if oChrom == chrom and oStrand == strand:

            contexts = coord_contexts.get(start, '-1').split(',')
            contexts = [int(x) for x in contexts]

            oNX.iContexts[oID] = contexts

    oNX.save()
Example #15
0
def updateContext(oFN, wigDir, chrom, strand, switchStrand=False):

    oNX = cgNexusFlat.Nexus(oFN, cgDegPeak.Peak)
    oNX.load(['tcc', 'context'])

    if switchStrand:
        strand = str(-int(strand))
    else:
        strand = str(strand)

    print 'loading wig'
    coord_contexts = cgWig.loadSingleWigContext(wigDir, chrom, strand,
                                                'context')
    print 'done loading'

    ds = bioLibCG.dominantSpotter([
        'C_EXON', 'C_3UTR', 'C_5UTR', 'NC_EXON', 'NC_3UTR', 'NC_5UTR',
        'C_INTRON', 'NC_INTRON', 'INTER'
    ])

    for oID in oNX.tcc:

        oChrom, oStrand, start, end = bioLibCG.tccSplit(oNX.tcc[oID])

        #deg wigs is AS to actual clipping site
        if switchStrand:
            oStrand = str(-int(strand))
        else:
            oStrand = str(oStrand)

        if oChrom == chrom and oStrand == strand:

            contexts = coord_contexts.get(start, 'INTER').split(',')
            oNX.context[oID] = ds.spotItem(contexts)

    oNX.save()