Example #1
0
def releases(request):
    release_id = request.GET.get('release_id')
    if release_id:
        releases = DataRelease.objects.filter(id=release_id).values().all()
    else:
        releases = DataRelease.objects.values().all()
    latest = DataRelease.objects.order_by('-id')[0].id
    change_types = {
        x['name']: x['id']
        for x in ChangeType.objects.values().all()
    }
    for release in releases:
        variants = Variant.objects.filter(Data_Release_id=release['id'])
        release['variants_added'] = variants.filter(
            Change_Type_id=change_types['new']).count()
        release['variants_classified'] = variants.filter(
            Q(Change_Type_id=change_types['changed_classification'])
            | Q(Change_Type_id=change_types['added_classification'])).count()
        release['variants_modified'] = variants.filter(
            Q(Change_Type_id=change_types['added_information'])
            | Q(Change_Type_id=change_types['changed_information'])).count()
        release['variants_deleted'] = variants.filter(
            Change_Type_id=change_types['deleted']).count()
    response = JsonResponse({"releases": list(releases), "latest": latest})
    response['Access-Control-Allow-Origin'] = '*'
    return response
Example #2
0
def range_filter(reference_genome, variants, reference_name, start, end):
    """Filters variants by range depending on the reference_genome"""
    if 'chr' in reference_name:
        reference_name = reference_name.replace('chr', '')
    variants = variants.filter(Chr=reference_name)
    if reference_genome == 'hg36':
        variants = variants.order_by('Hg36_Start')
        variants = variants.filter(Hg36_Start__lt=end, Hg36_End__gt=start)
    elif reference_genome == 'hg37':
        variants = variants.order_by('Hg37_Start')
        variants = variants.filter(Hg37_Start__lt=end, Hg37_End__gt=start)
    elif reference_genome == 'hg38':
        variants = variants.order_by('Hg38_Start')
        variants = variants.filter(Hg38_Start__lt=end, Hg38_End__gt=start)
    return variants
Example #3
0
def range_filter(reference_genome, variants, reference_name, start, end):
    """Filters variants by range depending on the reference_genome"""
    if 'chr' in reference_name:
        reference_name = reference_name.replace('chr', '')
    variants = variants.filter(Chr=reference_name)
    if reference_genome == 'hg36':
        variants = variants.order_by('Hg36_Start')
        variants = variants.filter(Hg36_Start__lt=end, Hg36_End__gt=start)
    elif reference_genome == 'hg37':
        variants = variants.order_by('Hg37_Start')
        variants = variants.filter(Hg37_Start__lt=end, Hg37_End__gt=start)
    elif reference_genome == 'hg38':
        variants = variants.order_by('Hg38_Start')
        variants = variants.filter(Hg38_Start__lt=end, Hg38_End__gt=start)

    return variants
Example #4
0
def releases(request):
    release_id = request.GET.get('release_id')
    if release_id:
        releases = DataRelease.objects.filter(id=release_id).values().all()
    else:
        releases = DataRelease.objects.values().all()
    latest = DataRelease.objects.order_by('-id')[0].id
    change_types = {x['name']: x['id'] for x in ChangeType.objects.values().all()}
    for release in releases:
        variants = Variant.objects.filter(Data_Release_id=release['id'])
        release['variants_added'] = variants.filter(Change_Type_id=change_types['new']).count()
        release['variants_classified'] = variants.filter(
            Q(Change_Type_id=change_types['changed_classification']) | Q(Change_Type_id=change_types['added_classification'])).count()
        release['variants_modified'] = variants.filter(
            Q(Change_Type_id=change_types['added_information']) | Q(Change_Type_id=change_types['changed_information'])).count()
        release['variants_deleted'] = variants.filter(Change_Type_id=change_types['deleted']).count()
    response = JsonResponse({"releases": list(releases), "latest": latest})
    response['Access-Control-Allow-Origin'] = '*'
    return response