def _init_design(self) -> Structure:
""" convert into nanodesign structure"""
converter = Converter()
converter.modify = True
converter.read_cadnano_file(self.json, None, self.seq)
converter.dna_structure.compute_aux_data()
return converter.dna_structure
def _create_hps_modifications(self) -> Tuple[List, List]:
""" create a list of all modified cadnano bases positions."""
# TODO: implement without reusing converter
converter = Converter()
converter.modify = False
converter.read_cadnano_file(self.json, None, self.seq)
converter.dna_structure.compute_aux_data()
dna_structure_del_ins = converter.dna_structure
hps_deletions = list()
hps_insertions = list()
for strand in dna_structure_del_ins.strands:
for base in strand.tour:
if base.num_insertions != 0:
hps_insertions.append(_hps(base))
elif base.num_deletions != 0:
hps_deletions.append(_hps(base))
return hps_deletions, hps_insertions