def has_degradation_increases_activity(data):
"""Check if the degradation of source causes activity of target
:param dict data:
"""
return part_has_modifier(data, SUBJECT, DEGRADATION) and part_has_modifier(
data, OBJECT, ACTIVITY)
def has_translocation_increases_activity(data):
"""Check if the tranclocation of source causes activity of target
:param dict data:
"""
return part_has_modifier(data, SUBJECT,
TRANSLOCATION) and part_has_modifier(
data, OBJECT, ACTIVITY)
def complex_increases_activity(graph, u, v, key):
"""If the complexing of v increases its activity"""
if graph.node[u][FUNCTION] != COMPLEX:
return False
if not complex_has_member(graph, u, v):
return False
return part_has_modifier(graph.edge[u][v][key], OBJECT, ACTIVITY)
def has_protein_modification_increases_activity(
graph: BELGraph,
source: BaseEntity,
target: BaseEntity,
key: str,
) -> bool:
"""Check if pmod of source causes activity of target."""
edge_data = graph[source][target][key]
return has_protein_modification(graph, source) and part_has_modifier(
edge_data, TARGET, ACTIVITY)
def has_protein_modification_increases_activity(graph, source, target, key):
"""Check if pmod of source causes activity of target
:param graph:
:param source:
:param target:
:param key:
:rtype:
"""
edge_data = graph.edge[source][target][key]
return has_protein_modification(graph, source) and part_has_modifier(
edge_data, OBJECT, ACTIVITY)
def complex_increases_activity(graph: BELGraph, u: BaseEntity, v: BaseEntity,
key: str) -> bool:
"""Return if the formation of a complex with u increases the activity of v."""
return (isinstance(u, (ComplexAbundance, NamedComplexAbundance))
and complex_has_member(graph, u, v)
and part_has_modifier(graph[u][v][key], TARGET, ACTIVITY))
def has_translocation_increases_activity(edge_data: EdgeData) -> bool:
"""Check if the translocation of source causes activity of target."""
return part_has_modifier(edge_data, SOURCE,
TRANSLOCATION) and part_has_modifier(
edge_data, TARGET, ACTIVITY)
def has_degradation_increases_activity(edge_data: EdgeData) -> bool:
"""Check if the degradation of source causes activity of target."""
return part_has_modifier(edge_data, SOURCE,
DEGRADATION) and part_has_modifier(
edge_data, TARGET, ACTIVITY)