def __init__(self, maf_file, annotations_file, regions_names, coding=True):

        Seq.__init__(self)

        self.coding = coding
        annotations = Importer.get_lines_from_file(annotations_file)
        maf_file = Importer.get_lines_from_file(maf_file)

        for region_name in regions_names:
            print(region_name)
            self.tri_num = 0
            self.mutation_number = 0

            self.trinucleotides_occurences = self.generate_empty_params()
            self.neutral_matrix = self.generate_empty_params()

            print('extracting annotations')
            regions = self.extract_regions_from_annotations(
                annotations, region_name)

            print('analysing sequence')
            self.analyse_maf_file(maf_file, regions)

            self.export_tri_occ_and_mutations(region_name)
            self.normalize_neutral_matrix()
            self.export_results(region_name)
            print()
Example #2
0
    def __init__(self, l=None):
        Seq.__init__(self)

        if l is None:
            self.data = []
        else:
            self.data = l