Exemple #1
0
    def __init__(self,
                 style=["typed", "directed"],
                 length=None,
                 types=[],
                 featureSet=None,
                 classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        assert (classSet.getId("neg") == 1)

        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
        if style.find(",") != -1:
            style = style.split(",")
        self.styles = style

        self.negFrac = None
        self.posPairGaz = POSPairGazetteer()
        for s in style:
            if s.find("negFrac") != -1:
                self.negFrac = float(s.split("_")[-1])
                print >> sys.stderr, "Downsampling negatives to", self.negFrac
                self.negRand = random.Random(15)
            elif s.find("posPairGaz") != -1:
                self.posPairGaz = POSPairGazetteer(
                    loadFrom=s.split("_", 1)[-1])

        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
        if "graph_kernel" in self.styles:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(
                self.featureSet)
        if "noAnnType" in self.styles:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if "noMasking" in self.styles:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if "maxFeatures" in self.styles:
            self.multiEdgeFeatureBuilder.maximum = True
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if "ontology" in self.styles:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(
                self.featureSet)
        if "nodalida" in self.styles:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(
                self.featureSet)
        #IF LOCAL
        if "bioinfer_limits" in self.styles:
            self.bioinferOntologies = OntologyUtils.getBioInferTempOntology()
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        #ENDIF
        self.pathLengths = length
        assert (self.pathLengths == None)
        self.types = types
        if "random" in self.styles:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)
 def __init__(self, style=["typed","directed"], length=None, types=[], featureSet=None, classSet=None):
     if featureSet == None:
         featureSet = IdSet()
     if classSet == None:
         classSet = IdSet(1)
     else:
         classSet = classSet
     assert( classSet.getId("neg") == 1 )
     
     ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
     if style.find(",") != -1:
         style = style.split(",")
     self.styles = style
     
     self.negFrac = None
     self.posPairGaz = POSPairGazetteer()
     for s in style:
         if s.find("negFrac") != -1:      
             self.negFrac = float(s.split("_")[-1])
             print >> sys.stderr, "Downsampling negatives to", self.negFrac
             self.negRand = random.Random(15)
         elif s.find("posPairGaz") != -1:
             self.posPairGaz = POSPairGazetteer(loadFrom=s.split("_", 1)[-1])
     
     self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
     self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
     if "graph_kernel" in self.styles:
         from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
         self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(self.featureSet)
     if "noAnnType" in self.styles:
         self.multiEdgeFeatureBuilder.noAnnType = True
     if "noMasking" in self.styles:
         self.multiEdgeFeatureBuilder.maskNamedEntities = False
     if "maxFeatures" in self.styles:
         self.multiEdgeFeatureBuilder.maximum = True
     self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
     if "ontology" in self.styles:
         self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(self.featureSet)
     if "nodalida" in self.styles:
         self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(self.featureSet)
     #IF LOCAL
     if "bioinfer_limits" in self.styles:
         self.bioinferOntologies = OntologyUtils.getBioInferTempOntology()
         #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
     #ENDIF
     self.pathLengths = length
     assert(self.pathLengths == None)
     self.types = types
     if "random" in self.styles:
         from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
         self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)
Exemple #3
0
    def __init__(self,
                 style=None,
                 classSet=None,
                 featureSet=None,
                 gazetteerFileName=None,
                 skiplist=None):
        if classSet == None:
            classSet = IdSet(1)
        assert (classSet.getId("neg") == 1)
        if featureSet == None:
            featureSet = IdSet()

        ExampleBuilder.__init__(self, classSet, featureSet)
        #gazetteerFileName="/usr/share/biotext/GeniaChallenge/SharedTaskTriggerTest/gazetteer-train"
        if gazetteerFileName != None:
            self.gazetteer = Gazetteer.loadGztr(gazetteerFileName)
            print >> sys.stderr, "Loaded gazetteer from", gazetteerFileName
        else:
            print >> sys.stderr, "No gazetteer loaded"
            self.gazetteer = None
        self.styles = style

        self.skiplist = set()
        if skiplist != None:
            f = open(skiplist, "rt")
            for line in f.readlines():
                self.skiplist.add(line.strip())
            f.close()

        self.styles = [
            "trigger_features", "typed", "directed", "no_linear", "entities",
            "genia_limits", "noMasking", "maxFeatures"
        ]
        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        if "graph_kernel" in self.styles:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(
                self.featureSet)
        if "noAnnType" in self.styles:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if "noMasking" in self.styles:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if "maxFeatures" in self.styles:
            self.multiEdgeFeatureBuilder.maximum = True

        self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
    def __init__(self, style=None, length=None, types=[], featureSet=None, classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        assert( classSet.getId("neg") == 1 or (len(classSet.Ids)== 2 and classSet.getId("neg") == -1) )
        
        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
        
        self.styles = self.getParameters(style, [
            "typed", "directed", "headsOnly", "graph_kernel", "noAnnType", "noMasking", "maxFeatures",
            "genia_limits", "epi_limits", "id_limits", "rel_limits", "bb_limits", "bi_limits", "co_limits",
            "genia_task1", "ontology", "nodalida", "bacteria_renaming", "trigger_features", "rel_features",
            "ddi_features", "evex", "giuliano", "random", "themeOnly", "causeOnly", "no_path", "entities", 
            "skip_extra_triggers", "headsOnly", "graph_kernel", "trigger_features", "no_task", "no_dependency", 
            "disable_entity_features", "disable_terminus_features", "disable_single_element_features", 
            "disable_ngram_features", "disable_path_edge_features", "no_linear", "subset", "binary", "pos_only",
            "entity_type"
        ])
        if style == None: # no parameters given
            style["typed"] = style["directed"] = style["headsOnly"] = True
#        self.styles = style
#        if "selftrain_group" in self.styles:
#            self.selfTrainGroups = set()
#            if "selftrain_group-1" in self.styles:
#                self.selfTrainGroups.add("-1")
#            if "selftrain_group0" in self.styles:
#                self.selfTrainGroups.add("0")
#            if "selftrain_group1" in self.styles:
#                self.selfTrainGroups.add("1")
#            if "selftrain_group2" in self.styles:
#                self.selfTrainGroups.add("2")
#            if "selftrain_group3" in self.styles:
#                self.selfTrainGroups.add("3")
#            print >> sys.stderr, "Self-train-groups:", self.selfTrainGroups
        
        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        # NOTE Temporarily re-enabling predicted range
        #self.multiEdgeFeatureBuilder.definePredictedValueRange([], None)
        if self.styles["graph_kernel"]:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(self.featureSet)
        if self.styles["noAnnType"]:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if self.styles["noMasking"]:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if self.styles["maxFeatures"]:
			self.multiEdgeFeatureBuilder.maximum = True
        if self.styles["genia_task1"]:
            self.multiEdgeFeatureBuilder.filterAnnTypes.add("Entity")
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if self.styles["ontology"]:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(self.featureSet)
        if self.styles["nodalida"]:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(self.featureSet)
        if self.styles["bacteria_renaming"]:
            self.bacteriaRenamingFeatureBuilder = BacteriaRenamingFeatureBuilder(self.featureSet)
        if self.styles["trigger_features"]:
            self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
            self.triggerFeatureBuilder.useNonNameEntities = True
            if self.styles["genia_task1"]:
                self.triggerFeatureBuilder.filterAnnTypes.add("Entity")
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        if self.styles["rel_features"]:
            self.relFeatureBuilder = RELFeatureBuilder(featureSet)
        if self.styles["ddi_features"]:
            self.drugFeatureBuilder = DrugFeatureBuilder(featureSet)
        if self.styles["evex"]:
            self.evexFeatureBuilder = EVEXFeatureBuilder(featureSet)
        if self.styles["giuliano"]:
            self.giulianoFeatureBuilder = GiulianoFeatureBuilder(featureSet)
        self.pathLengths = length
        assert(self.pathLengths == None)
        self.types = types
        if self.styles["random"]:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)
class MultiEdgeExampleBuilder(ExampleBuilder):
    """
    This example builder makes edge examples, i.e. examples describing
    the event arguments.
    """
    def __init__(self, style=None, length=None, types=[], featureSet=None, classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        assert( classSet.getId("neg") == 1 or (len(classSet.Ids)== 2 and classSet.getId("neg") == -1) )
        
        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
        
        self.styles = self.getParameters(style, [
            "typed", "directed", "headsOnly", "graph_kernel", "noAnnType", "noMasking", "maxFeatures",
            "genia_limits", "epi_limits", "id_limits", "rel_limits", "bb_limits", "bi_limits", "co_limits",
            "genia_task1", "ontology", "nodalida", "bacteria_renaming", "trigger_features", "rel_features",
            "ddi_features", "evex", "giuliano", "random", "themeOnly", "causeOnly", "no_path", "entities", 
            "skip_extra_triggers", "headsOnly", "graph_kernel", "trigger_features", "no_task", "no_dependency", 
            "disable_entity_features", "disable_terminus_features", "disable_single_element_features", 
            "disable_ngram_features", "disable_path_edge_features", "no_linear", "subset", "binary", "pos_only",
            "entity_type"
        ])
        if style == None: # no parameters given
            style["typed"] = style["directed"] = style["headsOnly"] = True
#        self.styles = style
#        if "selftrain_group" in self.styles:
#            self.selfTrainGroups = set()
#            if "selftrain_group-1" in self.styles:
#                self.selfTrainGroups.add("-1")
#            if "selftrain_group0" in self.styles:
#                self.selfTrainGroups.add("0")
#            if "selftrain_group1" in self.styles:
#                self.selfTrainGroups.add("1")
#            if "selftrain_group2" in self.styles:
#                self.selfTrainGroups.add("2")
#            if "selftrain_group3" in self.styles:
#                self.selfTrainGroups.add("3")
#            print >> sys.stderr, "Self-train-groups:", self.selfTrainGroups
        
        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        # NOTE Temporarily re-enabling predicted range
        #self.multiEdgeFeatureBuilder.definePredictedValueRange([], None)
        if self.styles["graph_kernel"]:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(self.featureSet)
        if self.styles["noAnnType"]:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if self.styles["noMasking"]:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if self.styles["maxFeatures"]:
			self.multiEdgeFeatureBuilder.maximum = True
        if self.styles["genia_task1"]:
            self.multiEdgeFeatureBuilder.filterAnnTypes.add("Entity")
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if self.styles["ontology"]:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(self.featureSet)
        if self.styles["nodalida"]:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(self.featureSet)
        if self.styles["bacteria_renaming"]:
            self.bacteriaRenamingFeatureBuilder = BacteriaRenamingFeatureBuilder(self.featureSet)
        if self.styles["trigger_features"]:
            self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
            self.triggerFeatureBuilder.useNonNameEntities = True
            if self.styles["genia_task1"]:
                self.triggerFeatureBuilder.filterAnnTypes.add("Entity")
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        if self.styles["rel_features"]:
            self.relFeatureBuilder = RELFeatureBuilder(featureSet)
        if self.styles["ddi_features"]:
            self.drugFeatureBuilder = DrugFeatureBuilder(featureSet)
        if self.styles["evex"]:
            self.evexFeatureBuilder = EVEXFeatureBuilder(featureSet)
        if self.styles["giuliano"]:
            self.giulianoFeatureBuilder = GiulianoFeatureBuilder(featureSet)
        self.pathLengths = length
        assert(self.pathLengths == None)
        self.types = types
        if self.styles["random"]:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)
    
    def definePredictedValueRange(self, sentences, elementName):
        self.multiEdgeFeatureBuilder.definePredictedValueRange(sentences, elementName)                        
    
    def getPredictedValueRange(self):
        return self.multiEdgeFeatureBuilder.predictedRange
    
    def filterEdgesByType(self, edges, typesToInclude):
        if len(typesToInclude) == 0:
            return edges
        edgesToKeep = []
        for edge in edges:
            if edge.get("type") in typesToInclude:
                edgesToKeep.append(edge)
        return edgesToKeep
    
    def getCategoryNameFromTokens(self, sentenceGraph, t1, t2, directed=True):
        """
        Example class. Multiple overlapping edges create a merged type.
        """
        types = set()
#        if sentenceGraph.interactionGraph.has_edge(t1, t2):
#            intEdges = sentenceGraph.interactionGraph.get_edge_data(t1, t2, default={})
#            # NOTE: Only works if keys are ordered integers
#            for i in range(len(intEdges)):
#                types.add(intEdges[i]["element"].get("type"))
#        if (not directed) and sentenceGraph.interactionGraph.has_edge(t2, t1):
#            intEdges = sentenceGraph.interactionGraph.get_edge(t2, t1, default={})
#            # NOTE: Only works if keys are ordered integers
#            for i in range(len(intEdges)):
#                types.add(intEdges[i]["element"].get("type"))
        intEdges = sentenceGraph.interactionGraph.getEdges(t1, t2)
        if (not directed):
            intEdges = intEdges + sentenceGraph.interactionGraph.getEdges(t2, t1)
        for intEdge in intEdges:
            types.add(intEdge[2].get("type"))
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if categoryName != "":
                categoryName += "---"
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"
        
    def getCategoryName(self, sentenceGraph, e1, e2, directed=True, duplicateEntities=None):
        """
        Example class. Multiple overlapping edges create a merged type.
        """
#        interactions = []
#        e1s = [e1]
#        if duplicateEntities != None and e1 in duplicateEntities:
#            e1s += duplicateEntities[e1]
#        e2s = [e2]
#        if duplicateEntities != None and e2 in duplicateEntities:
#            e2s += duplicateEntities[e2]
#        for entity1 in e1s:
#            for entity2 in e2s:
#                interactions = interactions + sentenceGraph.getInteractions(entity1, entity2)
#                if not directed:
#                    interactions = interactions + sentenceGraph.getInteractions(entity2, entity1)
        interactions = sentenceGraph.getInteractions(e1, e2, True)
        #print interactions
        
        types = set()
        for interaction in interactions:
            types.add(interaction[2].get("type"))
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if self.styles["causeOnly"] and name != "Cause":
                continue
            if self.styles["themeOnly"] and name != "Theme":
                continue
            if categoryName != "":
                categoryName += "---"
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"
    
    def isPotentialRELInteraction(self, e1, e2):
        if e1.get("type") == "Protein" and e2.get("type") == "Entity":
            return True
        else:
            return False

    def isPotentialBBInteraction(self, e1, e2, sentenceGraph):
        #if e1.get("type") == "Bacterium" and e2.get("type") in ["Host", "HostPart", "Geographical", "Environmental", "Food", "Medical", "Soil", "Water"]:
        # Note: "Environment" type is misspelled as "Environmental" in the BB-task documentation
        if e1.get("type") == "Bacterium" and e2.get("type") in ["Host", "HostPart", "Geographical", "Environment", "Food", "Medical", "Soil", "Water"]:
            return True
        elif e1.get("type") == "Host" and e2.get("type") == "HostPart":
            return True
        else:
            return False
    
    def getBISuperType(self, eType):
        if eType in ["GeneProduct", "Protein", "ProteinFamily", "PolymeraseComplex"]:
            return "ProteinEntity"
        elif eType in ["Gene", "GeneFamily", "GeneComplex", "Regulon", "Site", "Promoter"]:
            return "GeneEntity"
        else:
            return None
    
    def isPotentialBIInteraction(self, e1, e2, sentenceGraph, stats):
        e1Type = e1.get("type")
        e1SuperType = self.getBISuperType(e1Type)
        e2Type = e2.get("type")
        e2SuperType = self.getBISuperType(e2Type)
        
        tag = "(" + e1Type + "/" + e2Type + ")"
        if e1Type == "Regulon":
            if e2SuperType in ["GeneEntity", "ProteinEntity"]:
                return True
        if e1SuperType == "ProteinEntity":
            if e2Type in ["Site", "Promoter", "Gene", "GeneComplex"]:
                return True
        if e1Type in ["Action", "Transcription", "Expression"]:
            return True
        if e1Type == "Site":
            if e2SuperType == "GeneEntity":
                return True
        if e1Type == "Promoter":
            if e2SuperType in ["GeneEntity", "ProteinEntity"]:
                return True
        if e1SuperType in ["GeneEntity", "ProteinEntity"]:
            if e2SuperType in ["GeneEntity", "ProteinEntity"]:
                return True
        stats.filter("bi_limits") #+tag)
        return False

    def isPotentialEPIInteraction(self, e1, e2, sentenceGraph):
        if e1.get("type") != "Catalysis":
            if e1.get("type") in ["Protein", "Entity"]:
                return False
            elif e2.get("type") in ["Protein", "Entity"]:
                return True
            else:
                return False
        else: # Catalysis
            if e2.get("type") != "Entity":
                return True
            else:
                return False
        assert False, (e1.get("type"), e2.get("type"))

    def isPotentialIDInteraction(self, e1, e2, sentenceGraph):
        e1Type = e1.get("type")
        e2Type = e2.get("type")
        e1IsCore = e1Type in ["Protein", "Regulon-operon", "Two-component-system", "Chemical", "Organism"]
        e2IsCore = e2Type in ["Protein", "Regulon-operon", "Two-component-system", "Chemical", "Organism"]
        if e1IsCore:
            return False
        elif e1Type in ["Gene_expression", "Transcription"]:
            if e2Type in ["Protein", "Regulon-operon"]:
                return True
            else:
                return False
        elif e1Type in ["Protein_catabolism", "Phosphorylation"]:
            if e2Type == "Protein":
                return True
            else:
                return False
        elif e1Type == "Localization":
            if e2IsCore or e2Type == "Entity":
                return True
            else:
                return False
        elif e1Type in ["Binding", "Process"]:
            if e2IsCore:
                return True
            else:
                return False
        elif "egulation" in e1Type:
            if e2Type != "Entity":
                return True
            else:
                return False
        elif e1Type == "Entity":
            if e2IsCore:
                return True
            else:
                return False
        assert False, (e1Type, e2Type)
    
    def isPotentialCOInteraction(self, e1, e2, sentenceGraph):
        if e1.get("type") == "Exp" and e2.get("type") == "Exp":
            anaphoraTok = sentenceGraph.entityHeadTokenByEntity[e1]
            antecedentTok = sentenceGraph.entityHeadTokenByEntity[e2]
            antecedentTokenFound = False
            for token in sentenceGraph.tokens:
                if token == antecedentTok:
                    antecedentTokenFound = True
                if token == anaphoraTok: # if, not elif, to take into accoutn cases where e1Tok == e2Tok
                    if antecedentTokenFound:
                        return True
                    else:
                        return False
            assert False
        elif e1.get("type") == "Exp" and e2.get("type") == "Protein":
            return True
        else:
            return False
    
    def isPotentialGeniaInteraction(self, e1, e2):
        e1Type = e1.get("type")
        e2Type = e2.get("type")
        if e1Type == "Protein":
            return False
        elif e1Type in ["Entity", "Gene_expression", "Transcription", "Protein_catabolism", "Phosphorylation", "Binding"]:
            if e2Type == "Protein":
                return True
            else:
                return False
        elif e1Type == "Localization":
            if e2Type in ["Protein", "Entity"]:
                return True
            else:
                return False
        elif "egulation" in e1Type:
            if e2Type != "Entity":
                return True
            else:
                return False
        assert False, (e1Type, e2Type)

    def getGoldCategoryName(self, goldGraph, entityToGold, e1, e2, directed=True):
        if len(entityToGold[e1]) > 0 and len(entityToGold[e2]) > 0:
            return self.getCategoryName(goldGraph, entityToGold[e1][0], entityToGold[e2][0], directed=directed)
        else:
            return "neg"
                
    def buildExamplesFromGraph(self, sentenceGraph, outfile, goldGraph = None):
        """
        Build examples for a single sentence. Returns a list of examples.
        See Core/ExampleUtils for example format.
        """
        #examples = []
        exampleIndex = 0
        
        if self.styles["trigger_features"]: 
            self.triggerFeatureBuilder.initSentence(sentenceGraph)
        if self.styles["evex"]: 
            self.evexFeatureBuilder.initSentence(sentenceGraph)
            
        # Filter entities, if needed
        #mergedIds = None
        #duplicateEntities = None
        #entities = sentenceGraph.entities
        #entities, mergedIds, duplicateEntities = self.mergeEntities(sentenceGraph, False) # "no_duplicates" in self.styles)
        sentenceGraph.mergeInteractionGraph(True)
        entities = sentenceGraph.mergedEntities
        entityToDuplicates = sentenceGraph.mergedEntityToDuplicates
        self.exampleStats.addValue("Duplicate entities skipped", len(sentenceGraph.entities) - len(entities))
        
        # Connect to optional gold graph
        if goldGraph != None:
            entityToGold = EvaluateInteractionXML.mapEntities(entities, goldGraph.entities)
        
        paths = None
        if not self.styles["no_path"]:
            ##undirected = sentenceGraph.getUndirectedDependencyGraph()
            #undirected = self.nxMultiDiGraphToUndirected(sentenceGraph.dependencyGraph)
            ###undirected = sentenceGraph.dependencyGraph.to_undirected()
            ####undirected = NX10.MultiGraph(sentenceGraph.dependencyGraph) This didn't work
            undirected = sentenceGraph.dependencyGraph.toUndirected()
            #paths = NX10.all_pairs_shortest_path(undirected, cutoff=999)
            paths = undirected
        
        #for edge in sentenceGraph.dependencyGraph.edges:
        #    assert edge[2] != None
        #for edge in undirected.edges:
        #    assert edge[2] != None
        #if sentenceGraph.sentenceElement.get("id") == "GENIA.d70.s5":
        #    print [(x[0].get("id"), x[1].get("id"), x[2].get("id")) for x in sentenceGraph.dependencyGraph.edges]
        
        # Generate examples based on interactions between entities or interactions between tokens
        if self.styles["entities"]:
            loopRange = len(entities)
        else:
            loopRange = len(sentenceGraph.tokens)
        for i in range(loopRange-1):
            for j in range(i+1,loopRange):
                eI = None
                eJ = None
                if self.styles["entities"]:
                    eI = entities[i]
                    eJ = entities[j]
                    tI = sentenceGraph.entityHeadTokenByEntity[eI]
                    tJ = sentenceGraph.entityHeadTokenByEntity[eJ]
                    #if "no_ne_interactions" in self.styles and eI.get("isName") == "True" and eJ.get("isName") == "True":
                    #    continue
                    if eI.get("type") == "neg" or eJ.get("type") == "neg":
                        continue
                    if self.styles["skip_extra_triggers"]:
                        if eI.get("source") != None or eJ.get("source") != None:
                            continue
                else:
                    tI = sentenceGraph.tokens[i]
                    tJ = sentenceGraph.tokens[j]
                # only consider paths between entities (NOTE! entities, not only named entities)
                if self.styles["headsOnly"]:
                    if (len(sentenceGraph.tokenIsEntityHead[tI]) == 0) or (len(sentenceGraph.tokenIsEntityHead[tJ]) == 0):
                        continue
                
                if self.styles["directed"]:
                    # define forward
                    if self.styles["entities"]:
                        categoryName = self.getCategoryName(sentenceGraph, eI, eJ, True)
                        if goldGraph != None:
                            categoryName = self.getGoldCategoryName(goldGraph, entityToGold, eI, eJ, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(sentenceGraph, tI, tJ, True)
                    # make forward
                    self.exampleStats.beginExample(categoryName)
                    makeExample = True
                    if self.styles["genia_limits"] and not self.isPotentialGeniaInteraction(eI, eJ):
                        makeExample = False
                        self.exampleStats.filter("genia_limits")
                    if self.styles["genia_task1"] and (eI.get("type") == "Entity" or eJ.get("type") == "Entity"):
                        makeExample = False
                        self.exampleStats.filter("genia_task1")
                    if self.styles["rel_limits"] and not self.isPotentialRELInteraction(eI, eJ):
                        makeExample = False
                        self.exampleStats.filter("rel_limits")
                    if self.styles["co_limits"] and not self.isPotentialCOInteraction(eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("co_limits")
                    if self.styles["bb_limits"] and not self.isPotentialBBInteraction(eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("bb_limits")
                        if categoryName != "neg":
                            self.exampleStats.filter("bb_limits(" + categoryName + ":" + eI.get("type") + "/" + eJ.get("type") + ")")
                    if self.styles["bi_limits"] and not self.isPotentialBIInteraction(eI, eJ, sentenceGraph, self.exampleStats):
                        makeExample = False
                        #self.exampleStats.filter("bi_limits")
                    if self.styles["epi_limits"] and not self.isPotentialEPIInteraction(eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("epi_limits")
                    if self.styles["id_limits"] and not self.isPotentialIDInteraction(eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("id_limits")
#                    if self.styles["selftrain_limits"] and (eI.get("selftrain") == "False" or eJ.get("selftrain") == "False"):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_limits")
#                    if self.styles["selftrain_group"] and (eI.get("selftraingroup") not in self.selfTrainGroups or eJ.get("selftraingroup") not in self.selfTrainGroups):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_group")
                    if self.styles["pos_only"] and categoryName == "neg":
                        makeExample = False
                        self.exampleStats.filter("pos_only")
                    if makeExample:
                        #examples.append( self.buildExample(tI, tJ, paths, sentenceGraph, categoryName, exampleIndex, eI, eJ) )
                        ExampleUtils.appendExamples([self.buildExample(tI, tJ, paths, sentenceGraph, categoryName, exampleIndex, eI, eJ)], outfile)
                        exampleIndex += 1
                    self.exampleStats.endExample()
                    
                    # define reverse
                    if self.styles["entities"]:
                        categoryName = self.getCategoryName(sentenceGraph, eJ, eI, True)
                        if goldGraph != None:
                            categoryName = self.getGoldCategoryName(goldGraph, entityToGold, eJ, eI, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(sentenceGraph, tJ, tI, True)
                    # make reverse
                    self.exampleStats.beginExample(categoryName)
                    makeExample = True
                    if self.styles["genia_limits"] and not self.isPotentialGeniaInteraction(eJ, eI):
                        makeExample = False
                        self.exampleStats.filter("genia_limits")
                    if self.styles["genia_task1"] and (eI.get("type") == "Entity" or eJ.get("type") == "Entity"):
                        makeExample = False
                        self.exampleStats.filter("genia_task1")
                    if self.styles["rel_limits"] and not self.isPotentialRELInteraction(eJ, eI):
                        makeExample = False
                        self.exampleStats.filter("rel_limits")
                    if self.styles["co_limits"] and not self.isPotentialCOInteraction(eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("co_limits")
                    if self.styles["bb_limits"] and not self.isPotentialBBInteraction(eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("bb_limits")
                        if categoryName != "neg":
                            self.exampleStats.filter("bb_limits(" + categoryName + ":" + eJ.get("type") + "/" + eI.get("type") + ")")
                    if self.styles["bi_limits"] and not self.isPotentialBIInteraction(eJ, eI, sentenceGraph, self.exampleStats):
                        makeExample = False
                        #self.exampleStats.filter("bi_limits")
                    if self.styles["epi_limits"] and not self.isPotentialEPIInteraction(eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("epi_limits")
                    if self.styles["id_limits"] and not self.isPotentialIDInteraction(eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("id_limits")
#                    if self.styles["selftrain_limits"] and (eI.get("selftrain") == "False" or eJ.get("selftrain") == "False"):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_limits")
#                    if self.styles["selftrain_group"] and (eI.get("selftraingroup") not in self.selfTrainGroups or eJ.get("selftraingroup") not in self.selfTrainGroups):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_group")
                    if self.styles["pos_only"] and categoryName == "neg":
                        makeExample = False
                        self.exampleStats.filter("pos_only")
                    if makeExample:
                        #examples.append( self.buildExample(tJ, tI, paths, sentenceGraph, categoryName, exampleIndex, eJ, eI) )
                        ExampleUtils.appendExamples([self.buildExample(tJ, tI, paths, sentenceGraph, categoryName, exampleIndex, eJ, eI)], outfile)
                        exampleIndex += 1
                    self.exampleStats.endExample()
                else:
                    if self.styles["entities"]:
                        categoryName = self.getCategoryName(sentenceGraph, eI, eJ, False)
                    else:
                        categoryName = self.getCategoryNameFromTokens(sentenceGraph, tI, tJ, False)
                    self.exampleStats.beginExample(categoryName)
                    forwardExample = self.buildExample(tI, tJ, paths, sentenceGraph, categoryName, exampleIndex, eI, eJ)
                    if not self.styles["graph_kernel"]:
                        reverseExample = self.buildExample(tJ, tI, paths, sentenceGraph, categoryName, exampleIndex, eJ, eI)
                        forwardExample[2].update(reverseExample[2])
                    #examples.append(forwardExample)
                    ExampleUtils.appendExamples([forwardExample], outfile)
                    exampleIndex += 1
                    self.exampleStats.endExample()
        
        #return examples
        return exampleIndex
    
    def buildExample(self, token1, token2, paths, sentenceGraph, categoryName, exampleIndex, entity1=None, entity2=None):
        """
        Build a single directed example for the potential edge between token1 and token2
        """
        # dummy return for speed testing
        #return (sentenceGraph.getSentenceId()+".x"+str(exampleIndex),1,{},{})
    
        # define features
        features = {}
        if True: #token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
            #if token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
            #    path = paths[token1][token2]
            #else:
            #    path = [token1, token2]
            if not self.styles["no_path"]:
                # directedPath reduces performance by 0.01 pp
                #directedPath = sentenceGraph.dependencyGraph.getPaths(token1, token2)
                #if len(directedPath) == 0:
                #    directedPath = sentenceGraph.dependencyGraph.getPaths(token2, token1)
                #    for dp in directedPath:
                #        dp.reverse()
                #if len(directedPath) == 0:
                #    path = paths.getPaths(token1, token2)
                #else:
                #    path = directedPath
                
                path = paths.getPaths(token1, token2)
                if len(path) > 0:
                    #if len(path) > 1:
                    #    print len(path)
                    path = path[0]
                    pathExists = True
                else:
                    path = [token1, token2]
                    pathExists = False
            else:
                path = [token1, token2]
                pathExists = False
            #print token1.get("id"), token2.get("id")
            assert(self.pathLengths == None)
            if self.pathLengths == None or len(path)-1 in self.pathLengths:
#                if not "no_ontology" in self.styles:
#                    self.ontologyFeatureBuilder.setFeatureVector(features)
#                    self.ontologyFeatureBuilder.buildOntologyFeaturesForPath(sentenceGraph, path)
#                    self.ontologyFeatureBuilder.setFeatureVector(None)
                if self.styles["trigger_features"]: # F 85.52 -> 85.55
                    self.triggerFeatureBuilder.setFeatureVector(features)
                    self.triggerFeatureBuilder.tag = "trg1_"
                    self.triggerFeatureBuilder.buildFeatures(token1)
                    self.triggerFeatureBuilder.tag = "trg2_"
                    self.triggerFeatureBuilder.buildFeatures(token2)
                    self.triggerFeatureBuilder.setFeatureVector(None)
                # REL features
                if self.styles["rel_features"] and not self.styles["no_task"]:
                    self.relFeatureBuilder.setFeatureVector(features)
                    self.relFeatureBuilder.tag = "rel1_"
                    self.relFeatureBuilder.buildAllFeatures(sentenceGraph.tokens, sentenceGraph.tokens.index(token1))
                    self.relFeatureBuilder.tag = "rel2_"
                    self.relFeatureBuilder.buildAllFeatures(sentenceGraph.tokens, sentenceGraph.tokens.index(token2))
                    self.relFeatureBuilder.setFeatureVector(None)
                if self.styles["bacteria_renaming"] and not self.styles["no_task"]:
                    self.bacteriaRenamingFeatureBuilder.setFeatureVector(features)
                    self.bacteriaRenamingFeatureBuilder.buildPairFeatures(entity1, entity2)
                    #self.bacteriaRenamingFeatureBuilder.buildSubstringFeatures(entity1, entity2) # decreases perf. 74.76 -> 72.41
                    self.bacteriaRenamingFeatureBuilder.setFeatureVector(None)
                if self.styles["co_limits"] and not self.styles["no_task"]:
                    e1Offset = Range.charOffsetToSingleTuple(entity1.get("charOffset"))
                    e2Offset = Range.charOffsetToSingleTuple(entity2.get("charOffset"))
                    if Range.contains(e1Offset, e2Offset):
                        features[self.featureSet.getId("e1_contains_e2")] = 1
                        if entity2.get("isName") == "True":
                            features[self.featureSet.getId("e1_contains_e2name")] = 1
                    if Range.contains(e2Offset, e1Offset):
                        features[self.featureSet.getId("e2_contains_e1")] = 1
                        if entity1.get("isName") == "True":
                            features[self.featureSet.getId("e2_contains_e1name")] = 1
                if self.styles["ddi_features"]:
                    self.drugFeatureBuilder.setFeatureVector(features)
                    self.drugFeatureBuilder.tag = "ddi_"
                    self.drugFeatureBuilder.buildPairFeatures(entity1, entity2)  
                    if self.styles["ddi_mtmx"]:
                        self.drugFeatureBuilder.buildMTMXFeatures(entity1, entity2)
                    self.drugFeatureBuilder.setFeatureVector(None)
                #if "graph_kernel" in self.styles or not "no_dependency" in self.styles:
                #    #print "Getting edges"
                #    if token1 != token2 and pathExists:
                #        #print "g1"
                #        edges = self.multiEdgeFeatureBuilder.getEdges(sentenceGraph.dependencyGraph, path)
                #        #print "g2"
                #    else:
                #        edges = None
                if self.styles["graph_kernel"]:
                    self.graphKernelFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    self.graphKernelFeatureBuilder.buildGraphKernelFeatures(sentenceGraph, path)
                    self.graphKernelFeatureBuilder.setFeatureVector(None)
                if self.styles["entity_type"]:
                    features[self.featureSet.getId("e1_"+entity1.get("type"))] = 1
                    features[self.featureSet.getId("e2_"+entity2.get("type"))] = 1
                    features[self.featureSet.getId("distance_"+str(len(path)))] = 1
                if not self.styles["no_dependency"]:
                    #print "Dep features"
                    self.multiEdgeFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    #self.multiEdgeFeatureBuilder.buildStructureFeatures(sentenceGraph, paths) # remove for fast
                    if not self.styles["disable_entity_features"]:
                        self.multiEdgeFeatureBuilder.buildEntityFeatures(sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildPathLengthFeatures(path)
                    if not self.styles["disable_terminus_features"]:
                        self.multiEdgeFeatureBuilder.buildTerminusTokenFeatures(path, sentenceGraph) # remove for fast
                    if not self.styles["disable_single_element_features"]:
                        self.multiEdgeFeatureBuilder.buildSingleElementFeatures(path, sentenceGraph)
                    if not self.styles["disable_ngram_features"]:
                        #print "NGrams"
                        self.multiEdgeFeatureBuilder.buildPathGrams(2, path, sentenceGraph) # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(3, path, sentenceGraph) # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(4, path, sentenceGraph) # remove for fast
                    #self.buildEdgeCombinations(path, edges, sentenceGraph, features) # remove for fast
                    #if edges != None:
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[0], edges[0][1]+edges[1][0], "t1", sentenceGraph) # remove for fast
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[-1], edges[len(path)-1][len(path)-2]+edges[len(path)-2][len(path)-1], "t2", sentenceGraph) # remove for fast
                    if not self.styles["disable_path_edge_features"]:
                        self.multiEdgeFeatureBuilder.buildPathEdgeFeatures(path, sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildSentenceFeatures(sentenceGraph)
                    self.multiEdgeFeatureBuilder.setFeatureVector(None)
                if self.styles["nodalida"]:
                    self.nodalidaFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    shortestPaths = self.nodalidaFeatureBuilder.buildShortestPaths(sentenceGraph.dependencyGraph, path)
                    print shortestPaths
                    if len(shortestPaths) > 0:
                        self.nodalidaFeatureBuilder.buildNGrams(shortestPaths, sentenceGraph)
                    self.nodalidaFeatureBuilder.setFeatureVector(None)
                if not self.styles["no_linear"]:
                    self.tokenFeatureBuilder.setFeatureVector(features)
                    for i in range(len(sentenceGraph.tokens)):
                        if sentenceGraph.tokens[i] == token1:
                            token1Index = i
                        if sentenceGraph.tokens[i] == token2:
                            token2Index = i
                    linearPreTag = "linfw_"
                    if token1Index > token2Index: 
                        token1Index, token2Index = token2Index, token1Index
                        linearPreTag = "linrv_"
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(token1Index, sentenceGraph, 2, 2, preTag="linTok1")
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(token2Index, sentenceGraph, 2, 2, preTag="linTok2")
                    # Before, middle, after
    #                self.tokenFeatureBuilder.buildTokenGrams(0, token1Index-1, sentenceGraph, "bf")
    #                self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, "bw")
    #                self.tokenFeatureBuilder.buildTokenGrams(token2Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, "af")
                    # before-middle, middle, middle-after
#                    self.tokenFeatureBuilder.buildTokenGrams(0, token2Index-1, sentenceGraph, linearPreTag+"bf", max=2)
#                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, linearPreTag+"bw", max=2)
#                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, linearPreTag+"af", max=2)
                    self.tokenFeatureBuilder.setFeatureVector(None)
                if self.styles["random"]:
                    self.randomFeatureBuilder.setFeatureVector(features)
                    self.randomFeatureBuilder.buildRandomFeatures(100, 0.01)
                    self.randomFeatureBuilder.setFeatureVector(None)
                if self.styles["genia_limits"] and not self.styles["no_task"]:
                    e1Type = entity1.get("type")
                    e2Type = entity2.get("type")
                    assert(entity1.get("isName") == "False")
                    if entity2.get("isName") == "True":
                        features[self.featureSet.getId("GENIA_target_protein")] = 1
                    else:
                        features[self.featureSet.getId("GENIA_nested_event")] = 1
                    if e1Type.find("egulation") != -1: # leave r out to avoid problems with capitalization
                        if entity2.get("isName") == "True":
                            features[self.featureSet.getId("GENIA_regulation_of_protein")] = 1
                        else:
                            features[self.featureSet.getId("GENIA_regulation_of_event")] = 1
                if self.styles["bi_limits"]:
                    # Make features based on entity types
                    e1Type = entity1.get("type")
                    e2Type = entity2.get("type")
                    e1SuperType = str(self.getBISuperType(e1Type))
                    e2SuperType = str(self.getBISuperType(e2Type))
                    features[self.featureSet.getId("BI_e1_"+e1Type)] = 1
                    features[self.featureSet.getId("BI_e2_"+e2Type)] = 1
                    features[self.featureSet.getId("BI_e1sup_"+e1SuperType)] = 1
                    features[self.featureSet.getId("BI_e2sup_"+e2SuperType)] = 1
                    features[self.featureSet.getId("BI_e1e2_"+e1Type+"_"+e2Type)] = 1
                    features[self.featureSet.getId("BI_e1e2sup_"+e1SuperType+"_"+e2SuperType)] = 1
                if self.styles["evex"]:
                    self.evexFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    self.evexFeatureBuilder.buildEdgeFeatures(entity1, entity2, token1, token2, path, sentenceGraph)
                    self.evexFeatureBuilder.setFeatureVector(None)
                if self.styles["giuliano"]:
                    self.giulianoFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    self.giulianoFeatureBuilder.buildEdgeFeatures(entity1, entity2, token1, token2, path, sentenceGraph)
                    self.giulianoFeatureBuilder.setFeatureVector(None)
            else:
                features[self.featureSet.getId("always_negative")] = 1
                if self.styles["subset"]:
                    features[self.featureSet.getId("out_of_scope")] = 1
        else:
            features[self.featureSet.getId("always_negative")] = 1
            if self.styles["subset"]:
                features[self.featureSet.getId("out_of_scope")] = 1
            path = [token1, token2]
        # define extra attributes
        #if int(path[0].get("id").split("_")[-1]) < int(path[-1].get("id").split("_")[-1]):
        if int(path[0].get("charOffset").split("-")[0]) < int(path[-1].get("charOffset").split("-")[0]):
            #extra = {"xtype":"edge","type":"i","t1":path[0],"t2":path[-1]}
            extra = {"xtype":"edge","type":"i","t1":path[0].get("id"),"t2":path[-1].get("id")}
            extra["deprev"] = False
        else:
            #extra = {"xtype":"edge","type":"i","t1":path[-1],"t2":path[0]}
            extra = {"xtype":"edge","type":"i","t1":path[-1].get("id"),"t2":path[0].get("id")}
            extra["deprev"] = True
        if entity1 != None:
            #extra["e1"] = entity1
            extra["e1"] = entity1.get("id")
            if sentenceGraph.mergedEntityToDuplicates != None:
                #extra["e1GoldIds"] = mergedEntityIds[entity1]
                extra["e1DuplicateIds"] = ",".join([x.get("id") for x in sentenceGraph.mergedEntityToDuplicates[entity1]])
        if entity2 != None:
            #extra["e2"] = entity2
            extra["e2"] = entity2.get("id")
            if sentenceGraph.mergedEntityToDuplicates != None:
                extra["e2DuplicateIds"] = ",".join([x.get("id") for x in sentenceGraph.mergedEntityToDuplicates[entity2]])
                #extra["e2GoldIds"] = mergedEntityIds[entity2]
        extra["categoryName"] = categoryName
        if self.styles["bacteria_renaming"]:
            if entity1.get("text") != None and entity1.get("text") != "":
                extra["e1t"] = entity1.get("text").replace(" ", "---").replace(":","-COL-")
            if entity2.get("text") != None and entity2.get("text") != "":
                extra["e2t"] = entity2.get("text").replace(" ", "---").replace(":","-COL-")
        sentenceOrigId = sentenceGraph.sentenceElement.get("origId")
        if sentenceOrigId != None:
            extra["SOID"] = sentenceOrigId       
        # make example
        if self.styles["binary"]:
            if categoryName != "neg":
                category = 1
            else:
                category = -1
            categoryName = "i"
        else:
            category = self.classSet.getId(categoryName)
        
        # NOTE: temporarily disable for replicating 110310 experiment
        #features[self.featureSet.getId("extra_constant")] = 1
        return (sentenceGraph.getSentenceId()+".x"+str(exampleIndex),category,features,extra)
Exemple #6
0
 def __init__(self, style=None, types=[], featureSet=None, classSet=None):
     if featureSet == None:
         featureSet = IdSet()
     if classSet == None:
         classSet = IdSet(1)
     else:
         classSet = classSet
     
     ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
     assert( classSet.getId("neg") == 1 or (len(classSet.Ids)== 2 and classSet.getId("neg") == -1) )
     
     # Basic style = trigger_features:typed:directed:no_linear:entities:auto_limits:noMasking:maxFeatures
     self._setDefaultParameters([
         "directed", "undirected", "headsOnly", "graph_kernel", "noAnnType", "mask_nodes", "limit_features",
         "no_auto_limits", "co_features", "genia_features", "bi_features", #"genia_limits", "epi_limits", "id_limits", "rel_limits", "bb_limits", "bi_limits", "co_limits",
         "genia_task1", "ontology", "nodalida", "bacteria_renaming", "no_trigger_features", "rel_features",
         "drugbank_features", "ddi_mtmx", "evex", "giuliano", "random", "themeOnly", "causeOnly", "no_path", "token_nodes", 
         "skip_extra_triggers", "headsOnly", "graph_kernel", "no_task", "no_dependency", 
         "disable_entity_features", "disable_terminus_features", "disable_single_element_features", 
         "disable_ngram_features", "disable_path_edge_features", "linear_features", "subset", "binary", "pos_only",
         "entity_type", "filter_shortest_path", "maskTypeAsProtein", "keep_neg", "metamap", 
         "sdb_merge", "sdb_features", "ontobiotope_features", "no_self_loops", "full_entities",
         "no_features", "wordnet", "wordvector", "se10t8_undirected", "filter_types", "doc_extra",
         "entity_extra"])
     self.styles = self.getParameters(style)
     #if style == None: # no parameters given
     #    style["typed"] = style["directed"] = style["headsOnly"] = True
     
     self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet, self.styles)
     # NOTE Temporarily re-enabling predicted range
     #self.multiEdgeFeatureBuilder.definePredictedValueRange([], None)
     if self.styles["graph_kernel"]:
         from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
         self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(self.featureSet)
     if self.styles["noAnnType"]:
         self.multiEdgeFeatureBuilder.noAnnType = True
     if self.styles["mask_nodes"]:
         self.multiEdgeFeatureBuilder.maskNamedEntities = True
     else:
         self.multiEdgeFeatureBuilder.maskNamedEntities = False
     if not self.styles["limit_features"]:
         self.multiEdgeFeatureBuilder.maximum = True
     if self.styles["genia_task1"]:
         self.multiEdgeFeatureBuilder.filterAnnTypes.add("Entity")
     self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
     if self.styles["ontology"]:
         self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(self.featureSet)
     if self.styles["ontobiotope_features"]:
         self.ontobiotopeFeatureBuilder = OntoBiotopeFeatureBuilder(self.featureSet)
     if self.styles["nodalida"]:
         self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(self.featureSet)
     if self.styles["bacteria_renaming"]:
         self.bacteriaRenamingFeatureBuilder = BacteriaRenamingFeatureBuilder(self.featureSet)
     if not self.styles["no_trigger_features"]:
         self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet, self.styles)
         self.triggerFeatureBuilder.useNonNameEntities = True
         if self.styles["noAnnType"]:
             self.triggerFeatureBuilder.noAnnType = True
         if self.styles["genia_task1"]:
             self.triggerFeatureBuilder.filterAnnTypes.add("Entity")
         #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
     if self.styles["rel_features"]:
         self.relFeatureBuilder = RELFeatureBuilder(featureSet)
     if self.styles["drugbank_features"]:
         self.drugFeatureBuilder = DrugFeatureBuilder(featureSet)
     if self.styles["evex"]:
         self.evexFeatureBuilder = EVEXFeatureBuilder(featureSet)
     if self.styles["wordnet"]:
         self.wordNetFeatureBuilder = WordNetFeatureBuilder(featureSet)
     if self.styles["wordvector"]:
         self.wordVectorFeatureBuilder = WordVectorFeatureBuilder(featureSet, self.styles)
     if self.styles["giuliano"]:
         self.giulianoFeatureBuilder = GiulianoFeatureBuilder(featureSet)
     self.types = types
     if self.styles["random"]:
         from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
         self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)
Exemple #7
0
class EdgeExampleBuilder(ExampleBuilder):
    """
    This example builder makes edge examples, i.e. examples describing
    the event arguments.
    """
    def __init__(self, style=None, types=[], featureSet=None, classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        
        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
        assert( classSet.getId("neg") == 1 or (len(classSet.Ids)== 2 and classSet.getId("neg") == -1) )
        
        # Basic style = trigger_features:typed:directed:no_linear:entities:auto_limits:noMasking:maxFeatures
        self._setDefaultParameters([
            "directed", "undirected", "headsOnly", "graph_kernel", "noAnnType", "mask_nodes", "limit_features",
            "no_auto_limits", "co_features", "genia_features", "bi_features", #"genia_limits", "epi_limits", "id_limits", "rel_limits", "bb_limits", "bi_limits", "co_limits",
            "genia_task1", "ontology", "nodalida", "bacteria_renaming", "no_trigger_features", "rel_features",
            "drugbank_features", "ddi_mtmx", "evex", "giuliano", "random", "themeOnly", "causeOnly", "no_path", "token_nodes", 
            "skip_extra_triggers", "headsOnly", "graph_kernel", "no_task", "no_dependency", 
            "disable_entity_features", "disable_terminus_features", "disable_single_element_features", 
            "disable_ngram_features", "disable_path_edge_features", "linear_features", "subset", "binary", "pos_only",
            "entity_type", "filter_shortest_path", "maskTypeAsProtein", "keep_neg", "metamap", 
            "sdb_merge", "sdb_features", "ontobiotope_features", "no_self_loops", "full_entities",
            "no_features", "wordnet", "wordvector", "se10t8_undirected", "filter_types", "doc_extra",
            "entity_extra"])
        self.styles = self.getParameters(style)
        #if style == None: # no parameters given
        #    style["typed"] = style["directed"] = style["headsOnly"] = True
        
        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet, self.styles)
        # NOTE Temporarily re-enabling predicted range
        #self.multiEdgeFeatureBuilder.definePredictedValueRange([], None)
        if self.styles["graph_kernel"]:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(self.featureSet)
        if self.styles["noAnnType"]:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if self.styles["mask_nodes"]:
            self.multiEdgeFeatureBuilder.maskNamedEntities = True
        else:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if not self.styles["limit_features"]:
            self.multiEdgeFeatureBuilder.maximum = True
        if self.styles["genia_task1"]:
            self.multiEdgeFeatureBuilder.filterAnnTypes.add("Entity")
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if self.styles["ontology"]:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(self.featureSet)
        if self.styles["ontobiotope_features"]:
            self.ontobiotopeFeatureBuilder = OntoBiotopeFeatureBuilder(self.featureSet)
        if self.styles["nodalida"]:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(self.featureSet)
        if self.styles["bacteria_renaming"]:
            self.bacteriaRenamingFeatureBuilder = BacteriaRenamingFeatureBuilder(self.featureSet)
        if not self.styles["no_trigger_features"]:
            self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet, self.styles)
            self.triggerFeatureBuilder.useNonNameEntities = True
            if self.styles["noAnnType"]:
                self.triggerFeatureBuilder.noAnnType = True
            if self.styles["genia_task1"]:
                self.triggerFeatureBuilder.filterAnnTypes.add("Entity")
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        if self.styles["rel_features"]:
            self.relFeatureBuilder = RELFeatureBuilder(featureSet)
        if self.styles["drugbank_features"]:
            self.drugFeatureBuilder = DrugFeatureBuilder(featureSet)
        if self.styles["evex"]:
            self.evexFeatureBuilder = EVEXFeatureBuilder(featureSet)
        if self.styles["wordnet"]:
            self.wordNetFeatureBuilder = WordNetFeatureBuilder(featureSet)
        if self.styles["wordvector"]:
            self.wordVectorFeatureBuilder = WordVectorFeatureBuilder(featureSet, self.styles)
        if self.styles["giuliano"]:
            self.giulianoFeatureBuilder = GiulianoFeatureBuilder(featureSet)
        self.types = types
        if self.styles["random"]:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)
    
    def definePredictedValueRange(self, sentences, elementName):
        self.multiEdgeFeatureBuilder.definePredictedValueRange(sentences, elementName)                        
    
    def getPredictedValueRange(self):
        return self.multiEdgeFeatureBuilder.predictedRange
    
    def filterEdgesByType(self, edges, typesToInclude):
        if len(typesToInclude) == 0:
            return edges
        edgesToKeep = []
        for edge in edges:
            if edge.get("type") in typesToInclude:
                edgesToKeep.append(edge)
        return edgesToKeep
    
    def getCategoryNameFromTokens(self, sentenceGraph, t1, t2, directed=True):
        """
        Example class. Multiple overlapping edges create a merged type.
        """
        types = set()
        intEdges = sentenceGraph.interactionGraph.getEdges(t1, t2)
        if not directed:
            intEdges = intEdges + sentenceGraph.interactionGraph.getEdges(t2, t1)
        for intEdge in intEdges:
            types.add(intEdge[2].get("type"))
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if categoryName != "":
                categoryName += "---"
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"
        
    def getCategoryName(self, sentenceGraph, e1, e2, directed=True):
        """
        Example class. Multiple overlapping edges create a merged type.
        """
        interactions = sentenceGraph.getInteractions(e1, e2, True)
        if not directed and not self.styles["se10t8_undirected"]:
            interactions = interactions + sentenceGraph.getInteractions(e2, e1, True)
        
        types = set()
        for interaction in interactions:
            types.add(interaction[2].get("type"))
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if self.styles["causeOnly"] and name != "Cause":
                continue
            if self.styles["themeOnly"] and name != "Theme":
                continue
            if categoryName != "":
                categoryName += "---"
            if self.styles["sdb_merge"]:
                name = self.mergeForSeeDev(name, self.structureAnalyzer)
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"

    def getBISuperType(self, eType):
        if eType in ["GeneProduct", "Protein", "ProteinFamily", "PolymeraseComplex"]:
            return "ProteinEntity"
        elif eType in ["Gene", "GeneFamily", "GeneComplex", "Regulon", "Site", "Promoter"]:
            return "GeneEntity"
        else:
            return None
    
    def getSeeDevSuperTypes(self, eType):
        if eType in ("Gene", "Gene_Family", "Box", "Promoter"):
            return ("DNA", "Molecule")
        elif eType == "RNA":
            return ("RNA", "DNA_Product", "Molecule")
        elif eType in ("Protein", "Protein_Family", "Protein_Complex", "Protein_Domain"):
            return ("Amino_acid_sequence", "DNA_Product", "Molecule")
        elif eType == "Hormone":
            return ("Molecule",)
        elif eType in ("Regulatory_Network", "Pathway"):
            return ("Dynamic_process",)
        elif eType in ("Genotype", "Tissue", "Development_Phase"):
            return ("Biological_context", "Context")
        elif eType == "Environmental_Factor":
            return ("Context",)
        else:
            raise Exception("Unknown SeeDev type '" + str(eType) + "'")
    
    def mergeForSeeDev(self, categoryName, structureAnalyzer):
        if categoryName in structureAnalyzer.typeMap["forward"]:
            return structureAnalyzer.typeMap["forward"][categoryName]
        return categoryName
#         for tag in ("Regulates", "Exists", "Interacts", "Is", "Occurs"):
#             if categoryName.startswith(tag):
#                 categoryName = tag
#                 break
#         return categoryName
    
    def processCorpus(self, input, output, gold=None, append=False, allowNewIds=True, structureAnalyzer=None):
        if self.styles["sdb_merge"]:
            structureAnalyzer.determineNonOverlappingTypes()
            self.structureAnalyzer = structureAnalyzer
        ExampleBuilder.processCorpus(self, input, output, gold, append, allowNewIds, structureAnalyzer)
    
    def isValidInteraction(self, e1, e2, structureAnalyzer,forceUndirected=False):
        return len(structureAnalyzer.getValidEdgeTypes(e1.get("type"), e2.get("type"), forceUndirected=forceUndirected)) > 0

    def getGoldCategoryName(self, goldGraph, entityToGold, e1, e2, directed=True):
        if len(entityToGold[e1]) > 0 and len(entityToGold[e2]) > 0:
            return self.getCategoryName(goldGraph, entityToGold[e1][0], entityToGold[e2][0], directed=directed)
        else:
            return "neg"
    
    def filterEdge(self, edge, edgeTypes):
        import types
        assert edgeTypes != None
        if type(edgeTypes) not in [types.ListType, types.TupleType]:
            edgeTypes = [edgeTypes]
        if edge[2].get("type") in edgeTypes:
            return True
        else:
            return False
    
    def keepExample(self, e1, e2, categoryName, isDirected, structureAnalyzer):
        makeExample = True
        if (not self.styles["no_auto_limits"]) and not self.isValidInteraction(e1, e2, structureAnalyzer, forceUndirected=not isDirected):
            makeExample = False
            self.exampleStats.filter("auto_limits")
        if self.styles["genia_task1"] and (e1.get("type") == "Entity" or e2.get("type") == "Entity"):
            makeExample = False
            self.exampleStats.filter("genia_task1")
        if self.styles["pos_only"] and categoryName == "neg":
            makeExample = False
            self.exampleStats.filter("pos_only")
        if self.styles["no_self_loops"] and ((e1 == e2) or (e1.get("headOffset") == e2.get("headOffset"))):
            makeExample = False
            self.exampleStats.filter("no_self_loops")
        return makeExample
    
    def getExampleCategoryName(self, e1=None, e2=None, t1=None, t2=None, sentenceGraph=None, goldGraph=None, entityToGold=None, isDirected=True, structureAnalyzer=None):
        if self.styles["token_nodes"]:
            categoryName = self.getCategoryNameFromTokens(sentenceGraph, t1, t2, isDirected)
        else:
            categoryName = self.getCategoryName(sentenceGraph, e1, e2, isDirected)
            if goldGraph != None:
                categoryName = self.getGoldCategoryName(goldGraph, entityToGold, e1, e2, isDirected)
        if self.styles["filter_types"] != None and categoryName in self.styles["filter_types"]:
            categoryName = "neg"
        if self.styles["se10t8_undirected"]:
            assert e1.get("id").endswith(".e1")
            assert e2.get("id").endswith(".e2")
        #if self.styles["sdb_merge"]:
        #    categoryName = self.mergeForSeeDev(categoryName, structureAnalyzer)
        return categoryName
                
    def buildExamplesFromGraph(self, sentenceGraph, outfile, goldGraph = None, structureAnalyzer=None):
        """
        Build examples for a single sentence. Returns a list of examples.
        See Core/ExampleUtils for example format.
        """
        #examples = []
        exampleIndex = 0
        # example directionality
        if self.styles["directed"] == None and self.styles["undirected"] == None: # determine directedness from corpus
            examplesAreDirected = structureAnalyzer.hasDirectedTargets() if structureAnalyzer != None else True
        elif self.styles["directed"]:
            assert self.styles["undirected"] in [None, False]
            examplesAreDirected = True
        elif self.styles["undirected"]:
            assert self.styles["directed"] in [None, False]
            examplesAreDirected = False
        
        if not self.styles["no_trigger_features"]: 
            self.triggerFeatureBuilder.initSentence(sentenceGraph)
        if self.styles["evex"]: 
            self.evexFeatureBuilder.initSentence(sentenceGraph)
#         if self.styles["sdb_merge"]:
#             self.determineNonOverlappingTypes(structureAnalyzer)
            
        # Filter entities, if needed
        sentenceGraph.mergeInteractionGraph(True)
        entities = sentenceGraph.mergedEntities
        entityToDuplicates = sentenceGraph.mergedEntityToDuplicates
        self.exampleStats.addValue("Duplicate entities skipped", len(sentenceGraph.entities) - len(entities))
        
        # Connect to optional gold graph
        entityToGold = None
        if goldGraph != None:
            entityToGold = EvaluateInteractionXML.mapEntities(entities, goldGraph.entities)
        
        paths = None
        if not self.styles["no_path"]:
            undirected = sentenceGraph.dependencyGraph.toUndirected()
            paths = undirected
            if self.styles["filter_shortest_path"] != None: # For DDI use filter_shortest_path=conj_and
                paths.resetAnalyses() # just in case
                paths.FloydWarshall(self.filterEdge, {"edgeTypes":self.styles["filter_shortest_path"]})
        
        # Generate examples based on interactions between entities or interactions between tokens
        if self.styles["token_nodes"]:
            loopRange = len(sentenceGraph.tokens)
        else:
            loopRange = len(entities)
        for i in range(loopRange-1):
            for j in range(i+1,loopRange):
                eI = None
                eJ = None
                if self.styles["token_nodes"]:
                    tI = sentenceGraph.tokens[i]
                    tJ = sentenceGraph.tokens[j]
                else:
                    eI = entities[i]
                    eJ = entities[j]
                    tI = sentenceGraph.entityHeadTokenByEntity[eI]
                    tJ = sentenceGraph.entityHeadTokenByEntity[eJ]
                    if eI.get("type") == "neg" or eJ.get("type") == "neg":
                        continue
                    if self.styles["skip_extra_triggers"]:
                        if eI.get("source") != None or eJ.get("source") != None:
                            continue
                # only consider paths between entities (NOTE! entities, not only named entities)
                if self.styles["headsOnly"]:
                    if (len(sentenceGraph.tokenIsEntityHead[tI]) == 0) or (len(sentenceGraph.tokenIsEntityHead[tJ]) == 0):
                        continue
                
                examples = self.buildExamplesForPair(tI, tJ, paths, sentenceGraph, goldGraph, entityToGold, eI, eJ, structureAnalyzer, examplesAreDirected)
                for categoryName, features, extra in examples:
                    # make example
                    if self.styles["binary"]:
                        if categoryName != "neg":
                            category = 1
                        else:
                            category = -1
                        extra["categoryName"] = "i"
                    else:
                        category = self.classSet.getId(categoryName)
                    example = [sentenceGraph.getSentenceId()+".x"+str(exampleIndex), category, features, extra]
                    ExampleUtils.appendExamples([example], outfile)
                    exampleIndex += 1

        return exampleIndex
    
    def buildExamplesForPair(self, token1, token2, paths, sentenceGraph, goldGraph, entityToGold, entity1=None, entity2=None, structureAnalyzer=None, isDirected=True):
        # define forward
        categoryName = self.getExampleCategoryName(entity1, entity2, token1, token2, sentenceGraph, goldGraph, entityToGold, isDirected, structureAnalyzer=structureAnalyzer)
        # make forward
        forwardExample = None
        self.exampleStats.beginExample(categoryName)
        if self.keepExample(entity1, entity2, categoryName, isDirected, structureAnalyzer):
            forwardExample = self.buildExample(token1, token2, paths, sentenceGraph, categoryName, entity1, entity2, structureAnalyzer, isDirected)
        
        if isDirected: # build a separate reverse example (if that is valid)
            self.exampleStats.endExample() # end forward example
            # define reverse
            categoryName = self.getExampleCategoryName(entity2, entity1, token2, token1, sentenceGraph, goldGraph, entityToGold, True, structureAnalyzer=structureAnalyzer)
            # make reverse
            self.exampleStats.beginExample(categoryName)
            reverseExample = None
            if self.keepExample(entity2, entity1, categoryName, True, structureAnalyzer):
                reverseExample = self.buildExample(token2, token1, paths, sentenceGraph, categoryName, entity2, entity1, structureAnalyzer, isDirected)
            self.exampleStats.endExample()
            return filter(None, [forwardExample, reverseExample])
        elif self.styles["se10t8_undirected"]: # undirected example with a directed type
            self.exampleStats.endExample()
            return [forwardExample]
        elif forwardExample != None: # merge features from the reverse example to the forward one
            reverseExample = self.buildExample(token2, token1, paths, sentenceGraph, categoryName, entity2, entity1, structureAnalyzer, isDirected)
            forwardExample[1].update(reverseExample[1])
            self.exampleStats.endExample() # end merged example
            return [forwardExample]
        else: # undirected example that was filtered
            self.exampleStats.endExample() # end merged example
            return []
    
    def buildExample(self, token1, token2, paths, sentenceGraph, categoryName, entity1=None, entity2=None, structureAnalyzer=None, isDirected=True):
        """
        Build a single directed example for the potential edge between token1 and token2
        """
        # define features
        if not self.styles["no_path"]:
            path = paths.getPaths(token1, token2)
            if len(path) > 0:
                path = path[0]
                #pathExists = True
            else:
                path = [token1, token2]
                #pathExists = False
        else:
            path = [token1, token2]
            #pathExists = False
        
        features = {}
        if not self.styles["no_features"]:
            features = self.buildFeatures(sentenceGraph, entity1, entity2, token1, token2, path)
        
        # define extra attributes
        if int(path[0].get("charOffset").split("-")[0]) < int(path[-1].get("charOffset").split("-")[0]):
            extra = {"xtype":"edge","type":"i","t1":path[0].get("id"),"t2":path[-1].get("id")}
            extra["deprev"] = False
        else:
            extra = {"xtype":"edge","type":"i","t1":path[-1].get("id"),"t2":path[0].get("id")}
            extra["deprev"] = True
        if entity1 != None:
            extra["e1"] = entity1.get("id")
            if sentenceGraph.mergedEntityToDuplicates != None:
                extra["e1DuplicateIds"] = ",".join([x.get("id") for x in sentenceGraph.mergedEntityToDuplicates[entity1]])
        if entity2 != None:
            extra["e2"] = entity2.get("id")
            if sentenceGraph.mergedEntityToDuplicates != None:
                extra["e2DuplicateIds"] = ",".join([x.get("id") for x in sentenceGraph.mergedEntityToDuplicates[entity2]])
        extra["categoryName"] = categoryName
        if self.styles["bacteria_renaming"]:
            if entity1.get("text") != None and entity1.get("text") != "":
                extra["e1t"] = entity1.get("text").replace(" ", "---").replace(":","-COL-")
            if entity2.get("text") != None and entity2.get("text") != "":
                extra["e2t"] = entity2.get("text").replace(" ", "---").replace(":","-COL-")
        if self.styles["doc_extra"]:
            if hasattr(sentenceGraph, "documentElement") and sentenceGraph.documentElement.get("origId") != None:
                extra["DOID"] = sentenceGraph.documentElement.get("origId")
        if self.styles["entity_extra"]:
            if entity1.get("origId") != None: extra["e1OID"] = entity1.get("origId")
            if entity2.get("origId") != None: extra["e2OID"] = entity2.get("origId")
        sentenceOrigId = sentenceGraph.sentenceElement.get("origId")
        if sentenceOrigId != None:
            extra["SOID"] = sentenceOrigId 
        extra["directed"] = str(isDirected)
        if self.styles["sdb_merge"]:
            extra["sdb_merge"] = "True"
            #print extra
        
        return (categoryName, features, extra)
        
    
    def buildFeatures(self, sentenceGraph, entity1, entity2, token1, token2, path):
        features = {} 
        if not self.styles["no_trigger_features"]: # F 85.52 -> 85.55
            self.triggerFeatureBuilder.setFeatureVector(features)
            self.triggerFeatureBuilder.tag = "trg1_"
            self.triggerFeatureBuilder.buildFeatures(token1)
            self.triggerFeatureBuilder.tag = "trg2_"
            self.triggerFeatureBuilder.buildFeatures(token2)
            self.triggerFeatureBuilder.setFeatureVector(None)
        # REL features
        if self.styles["rel_features"] and not self.styles["no_task"]:
            self.relFeatureBuilder.setFeatureVector(features)
            self.relFeatureBuilder.tag = "rel1_"
            self.relFeatureBuilder.buildAllFeatures(sentenceGraph.tokens, sentenceGraph.tokens.index(token1))
            self.relFeatureBuilder.tag = "rel2_"
            self.relFeatureBuilder.buildAllFeatures(sentenceGraph.tokens, sentenceGraph.tokens.index(token2))
            self.relFeatureBuilder.setFeatureVector(None)
        if self.styles["bacteria_renaming"] and not self.styles["no_task"]:
            self.bacteriaRenamingFeatureBuilder.setFeatureVector(features)
            self.bacteriaRenamingFeatureBuilder.buildPairFeatures(entity1, entity2)
            #self.bacteriaRenamingFeatureBuilder.buildSubstringFeatures(entity1, entity2) # decreases perf. 74.76 -> 72.41
            self.bacteriaRenamingFeatureBuilder.setFeatureVector(None)
        if self.styles["co_features"] and not self.styles["no_task"]:
            e1Offset = Range.charOffsetToSingleTuple(entity1.get("charOffset"))
            e2Offset = Range.charOffsetToSingleTuple(entity2.get("charOffset"))
            if Range.contains(e1Offset, e2Offset):
                features[self.featureSet.getId("e1_contains_e2")] = 1
                if entity2.get("given") == "True":
                    features[self.featureSet.getId("e1_contains_e2name")] = 1
            if Range.contains(e2Offset, e1Offset):
                features[self.featureSet.getId("e2_contains_e1")] = 1
                if entity1.get("given") == "True":
                    features[self.featureSet.getId("e2_contains_e1name")] = 1
        if self.styles["drugbank_features"]:
            self.drugFeatureBuilder.setFeatureVector(features)
            self.drugFeatureBuilder.tag = "ddi_"
            self.drugFeatureBuilder.buildPairFeatures(entity1, entity2)  
            if self.styles["ddi_mtmx"]:
                self.drugFeatureBuilder.buildMTMXFeatures(entity1, entity2)
            self.drugFeatureBuilder.setFeatureVector(None)
        if self.styles["graph_kernel"]:
            self.graphKernelFeatureBuilder.setFeatureVector(features, entity1, entity2)
            self.graphKernelFeatureBuilder.buildGraphKernelFeatures(sentenceGraph, path)
            self.graphKernelFeatureBuilder.setFeatureVector(None)
        if self.styles["entity_type"]:
            e1Type = self.multiEdgeFeatureBuilder.getEntityType(entity1)
            e2Type = self.multiEdgeFeatureBuilder.getEntityType(entity2)
            features[self.featureSet.getId("e1_"+e1Type)] = 1
            features[self.featureSet.getId("e2_"+e2Type)] = 1
            features[self.featureSet.getId("distance_"+str(len(path)))] = 1
        if not self.styles["no_dependency"]:
            #print "Dep features"
            self.multiEdgeFeatureBuilder.setFeatureVector(features, entity1, entity2)
            #self.multiEdgeFeatureBuilder.buildStructureFeatures(sentenceGraph, paths) # remove for fast
            if not self.styles["disable_entity_features"]:
                self.multiEdgeFeatureBuilder.buildEntityFeatures(sentenceGraph)
            self.multiEdgeFeatureBuilder.buildPathLengthFeatures(path)
            if not self.styles["disable_terminus_features"]:
                self.multiEdgeFeatureBuilder.buildTerminusTokenFeatures(path, sentenceGraph) # remove for fast
            if not self.styles["disable_single_element_features"]:
                self.multiEdgeFeatureBuilder.buildSingleElementFeatures(path, sentenceGraph)
            if not self.styles["disable_ngram_features"]:
                #print "NGrams"
                self.multiEdgeFeatureBuilder.buildPathGrams(2, path, sentenceGraph) # remove for fast
                self.multiEdgeFeatureBuilder.buildPathGrams(3, path, sentenceGraph) # remove for fast
                self.multiEdgeFeatureBuilder.buildPathGrams(4, path, sentenceGraph) # remove for fast
            #self.buildEdgeCombinations(path, edges, sentenceGraph, features) # remove for fast
            #if edges != None:
            #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[0], edges[0][1]+edges[1][0], "t1", sentenceGraph) # remove for fast
            #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[-1], edges[len(path)-1][len(path)-2]+edges[len(path)-2][len(path)-1], "t2", sentenceGraph) # remove for fast
            if not self.styles["disable_path_edge_features"]:
                self.multiEdgeFeatureBuilder.buildPathEdgeFeatures(path, sentenceGraph)
            self.multiEdgeFeatureBuilder.buildSentenceFeatures(sentenceGraph)
            self.multiEdgeFeatureBuilder.setFeatureVector(None)
        if self.styles["nodalida"]:
            self.nodalidaFeatureBuilder.setFeatureVector(features, entity1, entity2)
            shortestPaths = self.nodalidaFeatureBuilder.buildShortestPaths(sentenceGraph.dependencyGraph, path)
            print shortestPaths
            if len(shortestPaths) > 0:
                self.nodalidaFeatureBuilder.buildNGrams(shortestPaths, sentenceGraph)
            self.nodalidaFeatureBuilder.setFeatureVector(None)
        if self.styles["linear_features"]:
            self.tokenFeatureBuilder.setFeatureVector(features)
            for i in range(len(sentenceGraph.tokens)):
                if sentenceGraph.tokens[i] == token1:
                    token1Index = i
                if sentenceGraph.tokens[i] == token2:
                    token2Index = i
            linearPreTag = "linfw_"
            if token1Index > token2Index: 
                token1Index, token2Index = token2Index, token1Index
                linearPreTag = "linrv_"
            self.tokenFeatureBuilder.buildLinearOrderFeatures(token1Index, sentenceGraph, 2, 2, preTag="linTok1")
            self.tokenFeatureBuilder.buildLinearOrderFeatures(token2Index, sentenceGraph, 2, 2, preTag="linTok2")
            # Before, middle, after
#                self.tokenFeatureBuilder.buildTokenGrams(0, token1Index-1, sentenceGraph, "bf")
#                self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, "bw")
#                self.tokenFeatureBuilder.buildTokenGrams(token2Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, "af")
            # before-middle, middle, middle-after
#                    self.tokenFeatureBuilder.buildTokenGrams(0, token2Index-1, sentenceGraph, linearPreTag+"bf", max=2)
#                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, linearPreTag+"bw", max=2)
#                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, linearPreTag+"af", max=2)
            self.tokenFeatureBuilder.setFeatureVector(None)
        if self.styles["random"]:
            self.randomFeatureBuilder.setFeatureVector(features)
            self.randomFeatureBuilder.buildRandomFeatures(100, 0.01)
            self.randomFeatureBuilder.setFeatureVector(None)
        if self.styles["genia_features"] and not self.styles["no_task"]:
            e1Type = entity1.get("type")
            e2Type = entity2.get("type")
            assert(entity1.get("given") in (None, "False"))
            if entity2.get("given") == "True":
                features[self.featureSet.getId("GENIA_target_protein")] = 1
            else:
                features[self.featureSet.getId("GENIA_nested_event")] = 1
            if e1Type.find("egulation") != -1: # leave r out to avoid problems with capitalization
                if entity2.get("given") == "True":
                    features[self.featureSet.getId("GENIA_regulation_of_protein")] = 1
                else:
                    features[self.featureSet.getId("GENIA_regulation_of_event")] = 1
        if self.styles["bi_features"]:
            # Make features based on entity types
            e1Type = entity1.get("type")
            e2Type = entity2.get("type")
            e1SuperType = str(self.getBISuperType(e1Type))
            e2SuperType = str(self.getBISuperType(e2Type))
            features[self.featureSet.getId("BI_e1_"+e1Type)] = 1
            features[self.featureSet.getId("BI_e2_"+e2Type)] = 1
            features[self.featureSet.getId("BI_e1sup_"+e1SuperType)] = 1
            features[self.featureSet.getId("BI_e2sup_"+e2SuperType)] = 1
            features[self.featureSet.getId("BI_e1e2_"+e1Type+"_"+e2Type)] = 1
            features[self.featureSet.getId("BI_e1e2sup_"+e1SuperType+"_"+e2SuperType)] = 1
        if self.styles["sdb_features"]:
            e1Type = entity1.get("type")
            e2Type = entity2.get("type")
            features[self.featureSet.getId("SDB_e1_"+e1Type)] = 1
            features[self.featureSet.getId("SDB_e2_"+e2Type)] = 1
            features[self.featureSet.getId("SDB_e1e2_"+e1Type+"_"+e2Type)] = 1
            if e1Type == e2Type:
                features[self.featureSet.getId("SDB_e1e2_equal")] = 1
                features[self.featureSet.getId("SDB_e1e2_equal_" + e1Type)] = 1
            e1SuperTypes = str(self.getSeeDevSuperTypes(e1Type))
            e2SuperTypes = str(self.getSeeDevSuperTypes(e2Type))
            for e1SuperType in e1SuperTypes:
                for e2SuperType in e2SuperTypes:
                    features[self.featureSet.getId("SDB_e1sup_"+e1SuperType)] = 1
                    features[self.featureSet.getId("SDB_e2sup_"+e2SuperType)] = 1
                    features[self.featureSet.getId("SDB_e1e2sup_"+e1SuperType+"_"+e2SuperType)] = 1
                    if e1SuperType == e2SuperType:
                        features[self.featureSet.getId("SDB_e1e2sup_equal")] = 1
                        features[self.featureSet.getId("SDB_e1e2sup_equal_" + e1SuperType)] = 1
        if self.styles["ontobiotope_features"]:
            self.ontobiotopeFeatureBuilder.setFeatureVector(features)
            self.ontobiotopeFeatureBuilder.buildOBOFeaturesForEntityPair(entity1, entity2)
            self.ontobiotopeFeatureBuilder.setFeatureVector(None)
        if self.styles["full_entities"]:
            e1Text = entity1.get("text").lower()
            e2Text = entity2.get("text").lower()
            features[self.featureSet.getId("FULL_e1_"+e1Text)] = 1
            features[self.featureSet.getId("FULL_e2_"+e2Text)] = 1
            for ep1 in e1Text.split():
                for ep2 in e2Text.split():
                    features[self.featureSet.getId("FULL_e1_"+ep1)] = 1
                    features[self.featureSet.getId("FULL_e2_"+ep2)] = 1
                    features[self.featureSet.getId("FULL_e1e2_"+ep1+"_"+ep2)] = 1
        if self.styles["evex"]:
            self.evexFeatureBuilder.setFeatureVector(features, entity1, entity2)
            self.evexFeatureBuilder.buildEdgeFeatures(entity1, entity2, token1, token2, path, sentenceGraph)
            self.evexFeatureBuilder.setFeatureVector(None)
        if self.styles["wordnet"]:
            self.wordNetFeatureBuilder.setFeatureVector(features, entity1, entity2)
            self.wordNetFeatureBuilder.buildFeaturesForEntityPair(token1, token2)
            self.wordNetFeatureBuilder.buildLinearFeatures(token1, sentenceGraph.tokens, tag="t1_")
            self.wordNetFeatureBuilder.buildLinearFeatures(token2, sentenceGraph.tokens, tag="t2_")
            self.wordNetFeatureBuilder.buildPathFeatures(path)
            self.wordNetFeatureBuilder.setFeatureVector(None)
        if self.styles["wordvector"]:
            self.wordVectorFeatureBuilder.setFeatureVector(features, entity1, entity2)
            self.wordVectorFeatureBuilder.buildFeatures(token1, "t1_")
            self.wordVectorFeatureBuilder.buildFeatures(token2, "t2_")
            self.wordVectorFeatureBuilder.buildLinearFeatures(token1, sentenceGraph.tokens, tag="t1_")
            self.wordVectorFeatureBuilder.buildLinearFeatures(token2, sentenceGraph.tokens, tag="t2_")
            self.wordVectorFeatureBuilder.buildPathFeatures(path)
            self.wordVectorFeatureBuilder.buildFBAFeatures(sentenceGraph.tokens, sentenceGraph.tokens.index(token1), sentenceGraph.tokens.index(token2))
            self.wordVectorFeatureBuilder.setFeatureVector(None)
        if self.styles["giuliano"]:
            self.giulianoFeatureBuilder.setFeatureVector(features, entity1, entity2)
            self.giulianoFeatureBuilder.buildEdgeFeatures(entity1, entity2, token1, token2, path, sentenceGraph)
            self.giulianoFeatureBuilder.setFeatureVector(None)
        
        return features
Exemple #8
0
class AsymmetricEventExampleBuilder(ExampleBuilder):
    def __init__(self,
                 style=["typed", "directed"],
                 length=None,
                 types=[],
                 featureSet=None,
                 classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        assert (classSet.getId("neg") == 1)

        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
        if style.find(",") != -1:
            style = style.split(",")
        self.styles = style

        self.negFrac = None
        self.posPairGaz = POSPairGazetteer()
        for s in style:
            if s.find("negFrac") != -1:
                self.negFrac = float(s.split("_")[-1])
                print >> sys.stderr, "Downsampling negatives to", self.negFrac
                self.negRand = random.Random(15)
            elif s.find("posPairGaz") != -1:
                self.posPairGaz = POSPairGazetteer(
                    loadFrom=s.split("_", 1)[-1])

        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
        if "graph_kernel" in self.styles:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(
                self.featureSet)
        if "noAnnType" in self.styles:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if "noMasking" in self.styles:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if "maxFeatures" in self.styles:
            self.multiEdgeFeatureBuilder.maximum = True
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if "ontology" in self.styles:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(
                self.featureSet)
        if "nodalida" in self.styles:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(
                self.featureSet)
        #IF LOCAL
        if "bioinfer_limits" in self.styles:
            self.bioinferOntologies = OntologyUtils.getBioInferTempOntology()
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        #ENDIF
        self.pathLengths = length
        assert (self.pathLengths == None)
        self.types = types
        if "random" in self.styles:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)

        #self.outFile = open("exampleTempFile.txt","wt")

    @classmethod
    def run(cls, input, output, parse, tokenization, style, idFileTag=None):
        classSet, featureSet = cls.getIdSets(idFileTag)
        if style != None:
            e = cls(style=style, classSet=classSet, featureSet=featureSet)
        else:
            e = cls(classSet=classSet, featureSet=featureSet)
        sentences = cls.getSentences(input, parse, tokenization)
        e.buildExamplesForSentences(sentences, output, idFileTag)
        if "printClassIds" in e.styles:
            print >> sys.stderr, e.classSet.Ids

    def definePredictedValueRange(self, sentences, elementName):
        self.multiEdgeFeatureBuilder.definePredictedValueRange(
            sentences, elementName)

    def getPredictedValueRange(self):
        return self.multiEdgeFeatureBuilder.predictedRange

    def filterEdgesByType(self, edges, typesToInclude):
        if len(typesToInclude) == 0:
            return edges
        edgesToKeep = []
        for edge in edges:
            if edge.get("type") in typesToInclude:
                edgesToKeep.append(edge)
        return edgesToKeep

    def getCategoryNameFromTokens(self, sentenceGraph, t1, t2, directed=True):
        types = set()
        themeE1Types = set()
        intEdges = []
        if sentenceGraph.interactionGraph.has_edge(t1, t2):
            intEdges = sentenceGraph.interactionGraph.get_edge_data(t1,
                                                                    t2,
                                                                    default={})
            # NOTE: Only works if keys are ordered integers
            for i in range(len(intEdges)):
                types.add(intEdges[i]["element"].get("type"))

#        if (not directed) and sentenceGraph.interactionGraph.has_edge(t2, t1):
#            intEdgesReverse = sentenceGraph.interactionGraph.get_edge(t2, t1, default={})
#            # NOTE: Only works if keys are ordered integers
#            for i in range(len(intEdgesReverse)):
#                intElement = intEdgesReverse[i]["element"]
#                intType = intElement.get("type")
#                types.add(intType)
#            intEdges.extend(intEdgesReverse)

        for i in range(len(intEdges)):
            intElement = intEdges[i]["element"]
            intType = intElement.get("type")
            if intType == "Theme":
                e1Entity = sentenceGraph.entitiesById[intElement.get("e1")]
                themeE1Types.add(e1Entity.get("type"))
            #types.add(intType)

        if len(themeE1Types) != 0:
            themeE1Types = list(themeE1Types)
            themeE1Types.sort()
            categoryName = ""
            for name in themeE1Types:
                if categoryName != "":
                    categoryName += "---"
                categoryName += name
            return categoryName
        else:
            types = list(types)
            types.sort()
            categoryName = ""
            for name in types:
                if categoryName != "":
                    categoryName += "---"
                categoryName += name
            if categoryName != "":
                return categoryName
            else:
                return "neg"

    def getCategoryName(self, sentenceGraph, e1, e2, directed=True):
        interactions = sentenceGraph.getInteractions(e1, e2)
        if not directed:
            interactions.extend(sentenceGraph.getInteractions(e2, e1))

        types = set()
        for interaction in interactions:
            types.add(interaction.attrib["type"])
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if categoryName != "":
                categoryName += "---"
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"

    def preProcessExamples(self, allExamples):
        # Duplicates cannot be removed here, as they should only be removed from the training set. This is done
        # in the classifier.
        #        if "no_duplicates" in self.styles:
        #            count = len(allExamples)
        #            print >> sys.stderr, " Removing duplicates,",
        #            allExamples = ExampleUtils.removeDuplicates(allExamples)
        #            print >> sys.stderr, "removed", count - len(allExamples)
        if "normalize" in self.styles:
            print >> sys.stderr, " Normalizing feature vectors"
            ExampleUtils.normalizeFeatureVectors(allExamples)
        return allExamples

    def isPotentialGeniaInteraction(self, e1, e2):
        if e1.get("isName") == "True":
            return False
        else:
            return True

    #IF LOCAL
    def getBioInferParentType(self, eType):
        if eType == "Physical_entity" or OntologyUtils.hasParent(
                eType, "Physical_entity", self.bioinferOntologies):
            return "Physical"
        elif eType == "Property_entity" or OntologyUtils.hasParent(
                eType, "Property_entity", self.bioinferOntologies):
            return "Property"
        elif OntologyUtils.hasParent(eType, "Relationship",
                                     self.bioinferOntologies):
            return "Process"
        else:
            assert False, eType

#        if self.bioinferOntologies["Entity"].has_key(eType):
#            if OntologyUtils.hasParent(eType, "Physical_entity", self.bioinferOntologies):
#                assert not OntologyUtils.hasParent(eType, "Property_entity", self.bioinferOntologies), eType
#                return "Physical"
#            else:
#                assert OntologyUtils.hasParent(eType, "Property_entity", self.bioinferOntologies), eType
#                return "Property"
#
#        else:
#            assert self.bioinferOntologies.has_key(eType), eType
#            #assert OntologyUtils.hasParent(eType, "Process_entity", self.bioinferOntologies["Relationship"]), eType
#            return "Process"

    def isPotentialBioInferInteraction(self, e1, e2, categoryName):
        e1Type = self.getBioInferParentType(e1.get("type"))
        e2Type = self.getBioInferParentType(e2.get("type"))
        if e1Type == "Process" or e1Type == "Property":
            return True
        elif e1Type == "Physical" and e2Type == "Physical":
            return True
        elif e1Type == "Physical" and e2Type == "Process":  # hack
            return True
        else:
            assert (
                categoryName == "neg"
            ), categoryName + " category for " + e1Type + " and " + e2Type
            return False

    #ENDIF

    def nxMultiDiGraphToUndirected(self, graph):
        undirected = NX10.MultiGraph(name=graph.name)
        undirected.add_nodes_from(graph)
        undirected.add_edges_from(graph.edges_iter())
        return undirected

    def buildExamples(self, sentenceGraph):
        examples = []
        exampleIndex = 0

        clearGraph = sentenceGraph.getCleared()

        #undirected = sentenceGraph.getUndirectedDependencyGraph()
        undirected = self.nxMultiDiGraphToUndirected(
            sentenceGraph.dependencyGraph)
        ##undirected = sentenceGraph.dependencyGraph.to_undirected()
        ###undirected = NX10.MultiGraph(sentenceGraph.dependencyGraph) This didn't work
        paths = NX10.all_pairs_shortest_path(undirected, cutoff=999)

        self.triggerFeatureBuilder.initSentence(clearGraph)

        # Generate examples based on interactions between entities or interactions between tokens
        if "entities" in self.styles:
            loopRange = len(sentenceGraph.entities)
        else:
            loopRange = len(sentenceGraph.tokens)
        #for i in range(loopRange-1):
        for i in range(loopRange):  # allow self-interactions
            #for j in range(i+1,loopRange):
            for j in range(i, loopRange):  # allow self-interactions
                eI = None
                eJ = None
                if "entities" in self.styles:
                    eI = sentenceGraph.entities[i]
                    eJ = sentenceGraph.entities[j]
                    tI = sentenceGraph.entityHeadTokenByEntity[eI]
                    tJ = sentenceGraph.entityHeadTokenByEntity[eJ]
                    #if "no_ne_interactions" in self.styles and eI.get("isName") == "True" and eJ.get("isName") == "True":
                    #    continue
                    if eI.get("type") == "neg" or eJ.get("type") == "neg":
                        continue
                else:
                    tI = sentenceGraph.tokens[i]
                    tJ = sentenceGraph.tokens[j]
#                # only consider paths between entities (NOTE! entities, not only named entities)
#                if "headsOnly" in self.styles:
#                    if (len(sentenceGraph.tokenIsEntityHead[tI]) == 0) or (len(sentenceGraph.tokenIsEntityHead[tJ]) == 0):
#                        continue

                if "directed" in self.styles:
                    # define forward
                    if "entities" in self.styles:
                        categoryName = self.getCategoryName(
                            sentenceGraph, eI, eJ, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(
                            sentenceGraph, tI, tJ, True)
                    self.exampleStats.beginExample(categoryName)
                    if self.negFrac == None or categoryName != "neg" or (
                            categoryName == "neg"
                            and self.negRand.random() < self.negFrac):
                        makeExample = True
                        if ("genia_limits" in self.styles
                            ) and not self.isPotentialGeniaInteraction(eI, eJ):
                            makeExample = False
                            self.exampleStats.filter("genia_limits")
                        if self.posPairGaz.getNegFrac(
                            (tI.get("POS"), tJ.get("POS"))) == 1.0:
                            makeExample = False
                            self.exampleStats.filter("pos_pair")
                        if makeExample:
                            if not sentenceGraph.tokenIsName[tI]:
                                examples.append(
                                    self.buildExample(tI, tJ, paths,
                                                      clearGraph, categoryName,
                                                      exampleIndex, eI, eJ))
                                exampleIndex += 1
                            else:
                                self.exampleStats.filter("genia_token_limits")
                    else:
                        self.exampleStats.filter("neg_frac")
                    self.exampleStats.endExample()

                    # define reverse
                    if "entities" in self.styles:
                        categoryName = self.getCategoryName(
                            sentenceGraph, eJ, eI, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(
                            sentenceGraph, tJ, tI, True)
                    self.exampleStats.beginExample(categoryName)
                    if self.negFrac == None or categoryName != "neg" or (
                            categoryName == "neg"
                            and self.negRand.random() < self.negFrac):
                        makeExample = True
                        if ("genia_limits" in self.styles
                            ) and not self.isPotentialGeniaInteraction(eJ, eI):
                            makeExample = False
                            self.exampleStats.filter("genia_limits")
                        if ("bioinfer_limits" in self.styles
                            ) and not self.isPotentialBioInferInteraction(
                                eJ, eI, categoryName):
                            makeExample = False
                            self.exampleStats.filter("bioinfer_limits")
                        if self.posPairGaz.getNegFrac(
                            (tJ.get("POS"), tI.get("POS"))) == 1.0:
                            makeExample = False
                            self.exampleStats.filter("pos_pair")
                        if makeExample:
                            if not sentenceGraph.tokenIsName[tJ]:
                                examples.append(
                                    self.buildExample(tJ, tI, paths,
                                                      clearGraph, categoryName,
                                                      exampleIndex, eJ, eI))
                                exampleIndex += 1
                            else:
                                self.exampleStats.filter("genia_token_limits")
                    else:
                        self.exampleStats.filter("neg_frac")
                    self.exampleStats.endExample()
#                else:
#                    if "entities" in self.styles:
#                        categoryName = self.getCategoryName(sentenceGraph, eI, eJ, False)
#                    else:
#                        categoryName = self.getCategoryNameFromTokens(sentenceGraph, tI, tJ, False)
#                    forwardExample = self.buildExample(tI, tJ, paths, clearGraph, categoryName, exampleIndex, eI, eJ)
#                    if not "graph_kernel" in self.styles:
#                        reverseExample = self.buildExample(tJ, tI, paths, clearGraph, categoryName, exampleIndex, eJ, eI)
#                        forwardExample[2].update(reverseExample[2])
#                    examples.append(forwardExample)
#                    exampleIndex += 1

        return examples

    def buildExample(self,
                     token1,
                     token2,
                     paths,
                     sentenceGraph,
                     categoryName,
                     exampleIndex,
                     entity1=None,
                     entity2=None):
        # define features
        features = {}
        if True:  #token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
            if token1 != token2 and paths.has_key(
                    token1) and paths[token1].has_key(token2):
                path = paths[token1][token2]
            else:
                path = [token1, token2]
            assert (self.pathLengths == None)
            if self.pathLengths == None or len(path) - 1 in self.pathLengths:
                if not "no_trigger":
                    self.triggerFeatureBuilder.setFeatureVector(self.features)
                    self.triggerFeatureBuilder.tag = "trg_t1_"
                    self.triggerFeatureBuilder.buildFeatures(eventToken)
                    self.triggerFeatureBuilder.tag = "trg_t2_"
                    self.triggerFeatureBuilder.buildFeatures(eventToken)
#                if not "no_ontology" in self.styles:
#                    self.ontologyFeatureBuilder.setFeatureVector(features)
#                    self.ontologyFeatureBuilder.buildOntologyFeaturesForPath(sentenceGraph, path)
#                    self.ontologyFeatureBuilder.setFeatureVector(None)
                if "graph_kernel" in self.styles or not "no_dependency" in self.styles:
                    if token1 != token2 and paths.has_key(
                            token1) and paths[token1].has_key(token2):
                        edges = self.multiEdgeFeatureBuilder.getEdges(
                            sentenceGraph.dependencyGraph, path)
                    else:
                        edges = None
                if "graph_kernel" in self.styles:
                    self.graphKernelFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    self.graphKernelFeatureBuilder.buildGraphKernelFeatures(
                        sentenceGraph, path, edges)
                    self.graphKernelFeatureBuilder.setFeatureVector(None)
                if "entity_type" in self.styles:
                    features[self.featureSet.getId("e1_" +
                                                   entity1.attrib["type"])] = 1
                    features[self.featureSet.getId("e2_" +
                                                   entity2.attrib["type"])] = 1
                    features[self.featureSet.getId("distance_" +
                                                   str(len(path)))] = 1
                if not "no_dependency" in self.styles:
                    if token1 == token2:
                        features[self.featureSet.getId("tokenSelfLoop")] = 1

                    self.multiEdgeFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    #self.multiEdgeFeatureBuilder.buildStructureFeatures(sentenceGraph, paths) # remove for fast
                    if not "disable_entity_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildEntityFeatures(
                            sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildPathLengthFeatures(path)
                    if not "disable_terminus_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildTerminusTokenFeatures(
                            path, sentenceGraph)  # remove for fast
                    if not "disable_single_element_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildSingleElementFeatures(
                            path, edges, sentenceGraph)
                    if not "disable_ngram_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildPathGrams(
                            2, path, edges, sentenceGraph)  # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(
                            3, path, edges, sentenceGraph)  # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(
                            4, path, edges, sentenceGraph)  # remove for fast
                    #self.buildEdgeCombinations(path, edges, sentenceGraph, features) # remove for fast
                    #if edges != None:
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[0], edges[0][1]+edges[1][0], "t1", sentenceGraph) # remove for fast
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[-1], edges[len(path)-1][len(path)-2]+edges[len(path)-2][len(path)-1], "t2", sentenceGraph) # remove for fast
                    if not "disable_path_edge_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildPathEdgeFeatures(
                            path, edges, sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildSentenceFeatures(
                        sentenceGraph)
                    self.multiEdgeFeatureBuilder.setFeatureVector(None)
                if "nodalida" in self.styles:
                    self.nodalidaFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    shortestPaths = self.nodalidaFeatureBuilder.buildShortestPaths(
                        sentenceGraph.dependencyGraph, path)
                    print shortestPaths
                    if len(shortestPaths) > 0:
                        self.nodalidaFeatureBuilder.buildNGrams(
                            shortestPaths, sentenceGraph)
                    self.nodalidaFeatureBuilder.setFeatureVector(None)
                if not "no_linear" in self.styles:
                    self.tokenFeatureBuilder.setFeatureVector(features)
                    for i in range(len(sentenceGraph.tokens)):
                        if sentenceGraph.tokens[i] == token1:
                            token1Index = i
                        if sentenceGraph.tokens[i] == token2:
                            token2Index = i
                    linearPreTag = "linfw_"
                    if token1Index > token2Index:
                        token1Index, token2Index = token2Index, token1Index
                        linearPreTag = "linrv_"
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(
                        token1Index, sentenceGraph, 2, 2, preTag="linTok1")
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(
                        token2Index, sentenceGraph, 2, 2, preTag="linTok2")
                    # Before, middle, after
                    #                self.tokenFeatureBuilder.buildTokenGrams(0, token1Index-1, sentenceGraph, "bf")
                    #                self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, "bw")
                    #                self.tokenFeatureBuilder.buildTokenGrams(token2Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, "af")
                    # before-middle, middle, middle-after
                    #                    self.tokenFeatureBuilder.buildTokenGrams(0, token2Index-1, sentenceGraph, linearPreTag+"bf", max=2)
                    #                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, linearPreTag+"bw", max=2)
                    #                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, linearPreTag+"af", max=2)
                    self.tokenFeatureBuilder.setFeatureVector(None)
                if "random" in self.styles:
                    self.randomFeatureBuilder.setFeatureVector(features)
                    self.randomFeatureBuilder.buildRandomFeatures(100, 0.01)
                    self.randomFeatureBuilder.setFeatureVector(None)
                if "genia_limits" in self.styles:
                    e1Type = entity1.get("type")
                    e2Type = entity2.get("type")
                    assert (entity1.get("isName") == "False")
                    if entity2.get("isName") == "True":
                        features[self.featureSet.getId(
                            "GENIA_target_protein")] = 1
                    else:
                        features[self.featureSet.getId(
                            "GENIA_nested_event")] = 1
                    if e1Type.find(
                            "egulation"
                    ) != -1:  # leave r out to avoid problems with capitalization
                        if entity2.get("isName") == "True":
                            features[self.featureSet.getId(
                                "GENIA_regulation_of_protein")] = 1
                        else:
                            features[self.featureSet.getId(
                                "GENIA_regulation_of_event")] = 1
            else:
                features[self.featureSet.getId("always_negative")] = 1
                if "subset" in self.styles:
                    features[self.featureSet.getId("out_of_scope")] = 1
        else:
            features[self.featureSet.getId("always_negative")] = 1
            if "subset" in self.styles:
                features[self.featureSet.getId("out_of_scope")] = 1
            path = [token1, token2]

        self.triggerFeatureBuilder.tag = ""
        self.triggerFeatureBuilder.setFeatureVector(None)

        # define extra attributes
        #        if int(path[0].attrib["id"].split("_")[-1]) < int(path[-1].attrib["id"].split("_")[-1]):
        #            #extra = {"xtype":"edge","type":"i","t1":path[0],"t2":path[-1]}
        #            extra = {"xtype":"asym","type":"i","t1":path[0].get("id"),"t2":path[-1].get("id")}
        #            extra["deprev"] = False
        #        else:
        #            #extra = {"xtype":"edge","type":"i","t1":path[-1],"t2":path[0]}
        #            extra = {"xtype":"asym","type":"i","t1":path[-1].get("id"),"t2":path[0].get("id")}
        #            extra["deprev"] = True

        extra = {
            "xtype": "asym",
            "type": "i",
            "t1": token1.get("id"),
            "t2": token2.get("id")
        }
        if entity1 != None:
            #extra["e1"] = entity1
            extra["e1"] = entity1.get("id")
        if entity2 != None:
            #extra["e2"] = entity2
            extra["e2"] = entity2.get("id")
        extra["categoryName"] = categoryName
        sentenceOrigId = sentenceGraph.sentenceElement.get("origId")
        if sentenceOrigId != None:
            extra["SOID"] = sentenceOrigId
        # make example
        if "binary" in self.styles:
            if categoryName != "neg":
                category = 1
            else:
                category = -1
            categoryName = "i"
        else:
            category = self.classSet.getId(categoryName)

        return (sentenceGraph.getSentenceId() + ".x" + str(exampleIndex),
                category, features, extra)
    def __init__(self,
                 style=None,
                 length=None,
                 types=[],
                 featureSet=None,
                 classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        assert (classSet.getId("neg") == 1
                or (len(classSet.Ids) == 2 and classSet.getId("neg") == -1))

        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)

        self.styles = self.getParameters(style, [
            "typed", "directed", "headsOnly", "graph_kernel", "noAnnType",
            "noMasking", "maxFeatures", "genia_limits", "epi_limits",
            "id_limits", "rel_limits", "bb_limits", "bi_limits", "co_limits",
            "genia_task1", "ontology", "nodalida", "bacteria_renaming",
            "trigger_features", "rel_features", "ddi_features", "evex",
            "giuliano", "random", "themeOnly", "causeOnly", "no_path",
            "entities", "skip_extra_triggers", "headsOnly", "graph_kernel",
            "trigger_features", "no_task", "no_dependency",
            "disable_entity_features", "disable_terminus_features",
            "disable_single_element_features", "disable_ngram_features",
            "disable_path_edge_features", "no_linear", "subset", "binary",
            "pos_only", "entity_type"
        ])
        if style == None:  # no parameters given
            style["typed"] = style["directed"] = style["headsOnly"] = True
#        self.styles = style
#        if "selftrain_group" in self.styles:
#            self.selfTrainGroups = set()
#            if "selftrain_group-1" in self.styles:
#                self.selfTrainGroups.add("-1")
#            if "selftrain_group0" in self.styles:
#                self.selfTrainGroups.add("0")
#            if "selftrain_group1" in self.styles:
#                self.selfTrainGroups.add("1")
#            if "selftrain_group2" in self.styles:
#                self.selfTrainGroups.add("2")
#            if "selftrain_group3" in self.styles:
#                self.selfTrainGroups.add("3")
#            print >> sys.stderr, "Self-train-groups:", self.selfTrainGroups

        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        # NOTE Temporarily re-enabling predicted range
        #self.multiEdgeFeatureBuilder.definePredictedValueRange([], None)
        if self.styles["graph_kernel"]:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(
                self.featureSet)
        if self.styles["noAnnType"]:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if self.styles["noMasking"]:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if self.styles["maxFeatures"]:
            self.multiEdgeFeatureBuilder.maximum = True
        if self.styles["genia_task1"]:
            self.multiEdgeFeatureBuilder.filterAnnTypes.add("Entity")
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if self.styles["ontology"]:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(
                self.featureSet)
        if self.styles["nodalida"]:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(
                self.featureSet)
        if self.styles["bacteria_renaming"]:
            self.bacteriaRenamingFeatureBuilder = BacteriaRenamingFeatureBuilder(
                self.featureSet)
        if self.styles["trigger_features"]:
            self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
            self.triggerFeatureBuilder.useNonNameEntities = True
            if self.styles["genia_task1"]:
                self.triggerFeatureBuilder.filterAnnTypes.add("Entity")
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        if self.styles["rel_features"]:
            self.relFeatureBuilder = RELFeatureBuilder(featureSet)
        if self.styles["ddi_features"]:
            self.drugFeatureBuilder = DrugFeatureBuilder(featureSet)
        if self.styles["evex"]:
            self.evexFeatureBuilder = EVEXFeatureBuilder(featureSet)
        if self.styles["giuliano"]:
            self.giulianoFeatureBuilder = GiulianoFeatureBuilder(featureSet)
        self.pathLengths = length
        assert (self.pathLengths == None)
        self.types = types
        if self.styles["random"]:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)
class MultiEdgeExampleBuilder(ExampleBuilder):
    """
    This example builder makes edge examples, i.e. examples describing
    the event arguments.
    """
    def __init__(self,
                 style=None,
                 length=None,
                 types=[],
                 featureSet=None,
                 classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        assert (classSet.getId("neg") == 1
                or (len(classSet.Ids) == 2 and classSet.getId("neg") == -1))

        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)

        self.styles = self.getParameters(style, [
            "typed", "directed", "headsOnly", "graph_kernel", "noAnnType",
            "noMasking", "maxFeatures", "genia_limits", "epi_limits",
            "id_limits", "rel_limits", "bb_limits", "bi_limits", "co_limits",
            "genia_task1", "ontology", "nodalida", "bacteria_renaming",
            "trigger_features", "rel_features", "ddi_features", "evex",
            "giuliano", "random", "themeOnly", "causeOnly", "no_path",
            "entities", "skip_extra_triggers", "headsOnly", "graph_kernel",
            "trigger_features", "no_task", "no_dependency",
            "disable_entity_features", "disable_terminus_features",
            "disable_single_element_features", "disable_ngram_features",
            "disable_path_edge_features", "no_linear", "subset", "binary",
            "pos_only", "entity_type"
        ])
        if style == None:  # no parameters given
            style["typed"] = style["directed"] = style["headsOnly"] = True
#        self.styles = style
#        if "selftrain_group" in self.styles:
#            self.selfTrainGroups = set()
#            if "selftrain_group-1" in self.styles:
#                self.selfTrainGroups.add("-1")
#            if "selftrain_group0" in self.styles:
#                self.selfTrainGroups.add("0")
#            if "selftrain_group1" in self.styles:
#                self.selfTrainGroups.add("1")
#            if "selftrain_group2" in self.styles:
#                self.selfTrainGroups.add("2")
#            if "selftrain_group3" in self.styles:
#                self.selfTrainGroups.add("3")
#            print >> sys.stderr, "Self-train-groups:", self.selfTrainGroups

        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        # NOTE Temporarily re-enabling predicted range
        #self.multiEdgeFeatureBuilder.definePredictedValueRange([], None)
        if self.styles["graph_kernel"]:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(
                self.featureSet)
        if self.styles["noAnnType"]:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if self.styles["noMasking"]:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if self.styles["maxFeatures"]:
            self.multiEdgeFeatureBuilder.maximum = True
        if self.styles["genia_task1"]:
            self.multiEdgeFeatureBuilder.filterAnnTypes.add("Entity")
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if self.styles["ontology"]:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(
                self.featureSet)
        if self.styles["nodalida"]:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(
                self.featureSet)
        if self.styles["bacteria_renaming"]:
            self.bacteriaRenamingFeatureBuilder = BacteriaRenamingFeatureBuilder(
                self.featureSet)
        if self.styles["trigger_features"]:
            self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
            self.triggerFeatureBuilder.useNonNameEntities = True
            if self.styles["genia_task1"]:
                self.triggerFeatureBuilder.filterAnnTypes.add("Entity")
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        if self.styles["rel_features"]:
            self.relFeatureBuilder = RELFeatureBuilder(featureSet)
        if self.styles["ddi_features"]:
            self.drugFeatureBuilder = DrugFeatureBuilder(featureSet)
        if self.styles["evex"]:
            self.evexFeatureBuilder = EVEXFeatureBuilder(featureSet)
        if self.styles["giuliano"]:
            self.giulianoFeatureBuilder = GiulianoFeatureBuilder(featureSet)
        self.pathLengths = length
        assert (self.pathLengths == None)
        self.types = types
        if self.styles["random"]:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)

    def definePredictedValueRange(self, sentences, elementName):
        self.multiEdgeFeatureBuilder.definePredictedValueRange(
            sentences, elementName)

    def getPredictedValueRange(self):
        return self.multiEdgeFeatureBuilder.predictedRange

    def filterEdgesByType(self, edges, typesToInclude):
        if len(typesToInclude) == 0:
            return edges
        edgesToKeep = []
        for edge in edges:
            if edge.get("type") in typesToInclude:
                edgesToKeep.append(edge)
        return edgesToKeep

    def getCategoryNameFromTokens(self, sentenceGraph, t1, t2, directed=True):
        """
        Example class. Multiple overlapping edges create a merged type.
        """
        types = set()
        #        if sentenceGraph.interactionGraph.has_edge(t1, t2):
        #            intEdges = sentenceGraph.interactionGraph.get_edge_data(t1, t2, default={})
        #            # NOTE: Only works if keys are ordered integers
        #            for i in range(len(intEdges)):
        #                types.add(intEdges[i]["element"].get("type"))
        #        if (not directed) and sentenceGraph.interactionGraph.has_edge(t2, t1):
        #            intEdges = sentenceGraph.interactionGraph.get_edge(t2, t1, default={})
        #            # NOTE: Only works if keys are ordered integers
        #            for i in range(len(intEdges)):
        #                types.add(intEdges[i]["element"].get("type"))
        intEdges = sentenceGraph.interactionGraph.getEdges(t1, t2)
        if (not directed):
            intEdges = intEdges + sentenceGraph.interactionGraph.getEdges(
                t2, t1)
        for intEdge in intEdges:
            types.add(intEdge[2].get("type"))
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if categoryName != "":
                categoryName += "---"
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"

    def getCategoryName(self,
                        sentenceGraph,
                        e1,
                        e2,
                        directed=True,
                        duplicateEntities=None):
        """
        Example class. Multiple overlapping edges create a merged type.
        """
        #        interactions = []
        #        e1s = [e1]
        #        if duplicateEntities != None and e1 in duplicateEntities:
        #            e1s += duplicateEntities[e1]
        #        e2s = [e2]
        #        if duplicateEntities != None and e2 in duplicateEntities:
        #            e2s += duplicateEntities[e2]
        #        for entity1 in e1s:
        #            for entity2 in e2s:
        #                interactions = interactions + sentenceGraph.getInteractions(entity1, entity2)
        #                if not directed:
        #                    interactions = interactions + sentenceGraph.getInteractions(entity2, entity1)
        interactions = sentenceGraph.getInteractions(e1, e2, True)
        #print interactions

        types = set()
        for interaction in interactions:
            types.add(interaction[2].get("type"))
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if self.styles["causeOnly"] and name != "Cause":
                continue
            if self.styles["themeOnly"] and name != "Theme":
                continue
            if categoryName != "":
                categoryName += "---"
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"

    def isPotentialRELInteraction(self, e1, e2):
        if e1.get("type") == "Protein" and e2.get("type") == "Entity":
            return True
        else:
            return False

    def isPotentialBBInteraction(self, e1, e2, sentenceGraph):
        #if e1.get("type") == "Bacterium" and e2.get("type") in ["Host", "HostPart", "Geographical", "Environmental", "Food", "Medical", "Soil", "Water"]:
        # Note: "Environment" type is misspelled as "Environmental" in the BB-task documentation
        if e1.get("type") == "Bacterium" and e2.get("type") in [
                "Host", "HostPart", "Geographical", "Environment", "Food",
                "Medical", "Soil", "Water"
        ]:
            return True
        elif e1.get("type") == "Host" and e2.get("type") == "HostPart":
            return True
        else:
            return False

    def getBISuperType(self, eType):
        if eType in [
                "GeneProduct", "Protein", "ProteinFamily", "PolymeraseComplex"
        ]:
            return "ProteinEntity"
        elif eType in [
                "Gene", "GeneFamily", "GeneComplex", "Regulon", "Site",
                "Promoter"
        ]:
            return "GeneEntity"
        else:
            return None

    def isPotentialBIInteraction(self, e1, e2, sentenceGraph, stats):
        e1Type = e1.get("type")
        e1SuperType = self.getBISuperType(e1Type)
        e2Type = e2.get("type")
        e2SuperType = self.getBISuperType(e2Type)

        tag = "(" + e1Type + "/" + e2Type + ")"
        if e1Type == "Regulon":
            if e2SuperType in ["GeneEntity", "ProteinEntity"]:
                return True
        if e1SuperType == "ProteinEntity":
            if e2Type in ["Site", "Promoter", "Gene", "GeneComplex"]:
                return True
        if e1Type in ["Action", "Transcription", "Expression"]:
            return True
        if e1Type == "Site":
            if e2SuperType == "GeneEntity":
                return True
        if e1Type == "Promoter":
            if e2SuperType in ["GeneEntity", "ProteinEntity"]:
                return True
        if e1SuperType in ["GeneEntity", "ProteinEntity"]:
            if e2SuperType in ["GeneEntity", "ProteinEntity"]:
                return True
        stats.filter("bi_limits")  #+tag)
        return False

    def isPotentialEPIInteraction(self, e1, e2, sentenceGraph):
        if e1.get("type") != "Catalysis":
            if e1.get("type") in ["Protein", "Entity"]:
                return False
            elif e2.get("type") in ["Protein", "Entity"]:
                return True
            else:
                return False
        else:  # Catalysis
            if e2.get("type") != "Entity":
                return True
            else:
                return False
        assert False, (e1.get("type"), e2.get("type"))

    def isPotentialIDInteraction(self, e1, e2, sentenceGraph):
        e1Type = e1.get("type")
        e2Type = e2.get("type")
        e1IsCore = e1Type in [
            "Protein", "Regulon-operon", "Two-component-system", "Chemical",
            "Organism"
        ]
        e2IsCore = e2Type in [
            "Protein", "Regulon-operon", "Two-component-system", "Chemical",
            "Organism"
        ]
        if e1IsCore:
            return False
        elif e1Type in ["Gene_expression", "Transcription"]:
            if e2Type in ["Protein", "Regulon-operon"]:
                return True
            else:
                return False
        elif e1Type in ["Protein_catabolism", "Phosphorylation"]:
            if e2Type == "Protein":
                return True
            else:
                return False
        elif e1Type == "Localization":
            if e2IsCore or e2Type == "Entity":
                return True
            else:
                return False
        elif e1Type in ["Binding", "Process"]:
            if e2IsCore:
                return True
            else:
                return False
        elif "egulation" in e1Type:
            if e2Type != "Entity":
                return True
            else:
                return False
        elif e1Type == "Entity":
            if e2IsCore:
                return True
            else:
                return False
        assert False, (e1Type, e2Type)

    def isPotentialCOInteraction(self, e1, e2, sentenceGraph):
        if e1.get("type") == "Exp" and e2.get("type") == "Exp":
            anaphoraTok = sentenceGraph.entityHeadTokenByEntity[e1]
            antecedentTok = sentenceGraph.entityHeadTokenByEntity[e2]
            antecedentTokenFound = False
            for token in sentenceGraph.tokens:
                if token == antecedentTok:
                    antecedentTokenFound = True
                if token == anaphoraTok:  # if, not elif, to take into accoutn cases where e1Tok == e2Tok
                    if antecedentTokenFound:
                        return True
                    else:
                        return False
            assert False
        elif e1.get("type") == "Exp" and e2.get("type") == "Protein":
            return True
        else:
            return False

    def isPotentialGeniaInteraction(self, e1, e2):
        e1Type = e1.get("type")
        e2Type = e2.get("type")
        if e1Type == "Protein":
            return False
        elif e1Type in [
                "Entity", "Gene_expression", "Transcription",
                "Protein_catabolism", "Phosphorylation", "Binding"
        ]:
            if e2Type == "Protein":
                return True
            else:
                return False
        elif e1Type == "Localization":
            if e2Type in ["Protein", "Entity"]:
                return True
            else:
                return False
        elif "egulation" in e1Type:
            if e2Type != "Entity":
                return True
            else:
                return False
        assert False, (e1Type, e2Type)

    def getGoldCategoryName(self,
                            goldGraph,
                            entityToGold,
                            e1,
                            e2,
                            directed=True):
        if len(entityToGold[e1]) > 0 and len(entityToGold[e2]) > 0:
            return self.getCategoryName(goldGraph,
                                        entityToGold[e1][0],
                                        entityToGold[e2][0],
                                        directed=directed)
        else:
            return "neg"

    def buildExamplesFromGraph(self, sentenceGraph, outfile, goldGraph=None):
        """
        Build examples for a single sentence. Returns a list of examples.
        See Core/ExampleUtils for example format.
        """
        #examples = []
        exampleIndex = 0

        if self.styles["trigger_features"]:
            self.triggerFeatureBuilder.initSentence(sentenceGraph)
        if self.styles["evex"]:
            self.evexFeatureBuilder.initSentence(sentenceGraph)

        # Filter entities, if needed
        #mergedIds = None
        #duplicateEntities = None
        #entities = sentenceGraph.entities
        #entities, mergedIds, duplicateEntities = self.mergeEntities(sentenceGraph, False) # "no_duplicates" in self.styles)
        sentenceGraph.mergeInteractionGraph(True)
        entities = sentenceGraph.mergedEntities
        entityToDuplicates = sentenceGraph.mergedEntityToDuplicates
        self.exampleStats.addValue("Duplicate entities skipped",
                                   len(sentenceGraph.entities) - len(entities))

        # Connect to optional gold graph
        if goldGraph != None:
            entityToGold = EvaluateInteractionXML.mapEntities(
                entities, goldGraph.entities)

        paths = None
        if not self.styles["no_path"]:
            ##undirected = sentenceGraph.getUndirectedDependencyGraph()
            #undirected = self.nxMultiDiGraphToUndirected(sentenceGraph.dependencyGraph)
            ###undirected = sentenceGraph.dependencyGraph.to_undirected()
            ####undirected = NX10.MultiGraph(sentenceGraph.dependencyGraph) This didn't work
            undirected = sentenceGraph.dependencyGraph.toUndirected()
            #paths = NX10.all_pairs_shortest_path(undirected, cutoff=999)
            paths = undirected

        #for edge in sentenceGraph.dependencyGraph.edges:
        #    assert edge[2] != None
        #for edge in undirected.edges:
        #    assert edge[2] != None
        #if sentenceGraph.sentenceElement.get("id") == "GENIA.d70.s5":
        #    print [(x[0].get("id"), x[1].get("id"), x[2].get("id")) for x in sentenceGraph.dependencyGraph.edges]

        # Generate examples based on interactions between entities or interactions between tokens
        if self.styles["entities"]:
            loopRange = len(entities)
        else:
            loopRange = len(sentenceGraph.tokens)
        for i in range(loopRange - 1):
            for j in range(i + 1, loopRange):
                eI = None
                eJ = None
                if self.styles["entities"]:
                    eI = entities[i]
                    eJ = entities[j]
                    tI = sentenceGraph.entityHeadTokenByEntity[eI]
                    tJ = sentenceGraph.entityHeadTokenByEntity[eJ]
                    #if "no_ne_interactions" in self.styles and eI.get("isName") == "True" and eJ.get("isName") == "True":
                    #    continue
                    if eI.get("type") == "neg" or eJ.get("type") == "neg":
                        continue
                    if self.styles["skip_extra_triggers"]:
                        if eI.get("source") != None or eJ.get(
                                "source") != None:
                            continue
                else:
                    tI = sentenceGraph.tokens[i]
                    tJ = sentenceGraph.tokens[j]
                # only consider paths between entities (NOTE! entities, not only named entities)
                if self.styles["headsOnly"]:
                    if (len(sentenceGraph.tokenIsEntityHead[tI]) == 0) or (len(
                            sentenceGraph.tokenIsEntityHead[tJ]) == 0):
                        continue

                if self.styles["directed"]:
                    # define forward
                    if self.styles["entities"]:
                        categoryName = self.getCategoryName(
                            sentenceGraph, eI, eJ, True)
                        if goldGraph != None:
                            categoryName = self.getGoldCategoryName(
                                goldGraph, entityToGold, eI, eJ, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(
                            sentenceGraph, tI, tJ, True)
                    # make forward
                    self.exampleStats.beginExample(categoryName)
                    makeExample = True
                    if self.styles[
                            "genia_limits"] and not self.isPotentialGeniaInteraction(
                                eI, eJ):
                        makeExample = False
                        self.exampleStats.filter("genia_limits")
                    if self.styles["genia_task1"] and (
                            eI.get("type") == "Entity"
                            or eJ.get("type") == "Entity"):
                        makeExample = False
                        self.exampleStats.filter("genia_task1")
                    if self.styles[
                            "rel_limits"] and not self.isPotentialRELInteraction(
                                eI, eJ):
                        makeExample = False
                        self.exampleStats.filter("rel_limits")
                    if self.styles[
                            "co_limits"] and not self.isPotentialCOInteraction(
                                eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("co_limits")
                    if self.styles[
                            "bb_limits"] and not self.isPotentialBBInteraction(
                                eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("bb_limits")
                        if categoryName != "neg":
                            self.exampleStats.filter("bb_limits(" +
                                                     categoryName + ":" +
                                                     eI.get("type") + "/" +
                                                     eJ.get("type") + ")")
                    if self.styles[
                            "bi_limits"] and not self.isPotentialBIInteraction(
                                eI, eJ, sentenceGraph, self.exampleStats):
                        makeExample = False
                        #self.exampleStats.filter("bi_limits")
                    if self.styles[
                            "epi_limits"] and not self.isPotentialEPIInteraction(
                                eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("epi_limits")
                    if self.styles[
                            "id_limits"] and not self.isPotentialIDInteraction(
                                eI, eJ, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("id_limits")
#                    if self.styles["selftrain_limits"] and (eI.get("selftrain") == "False" or eJ.get("selftrain") == "False"):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_limits")
#                    if self.styles["selftrain_group"] and (eI.get("selftraingroup") not in self.selfTrainGroups or eJ.get("selftraingroup") not in self.selfTrainGroups):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_group")
                    if self.styles["pos_only"] and categoryName == "neg":
                        makeExample = False
                        self.exampleStats.filter("pos_only")
                    if makeExample:
                        #examples.append( self.buildExample(tI, tJ, paths, sentenceGraph, categoryName, exampleIndex, eI, eJ) )
                        ExampleUtils.appendExamples([
                            self.buildExample(tI, tJ, paths, sentenceGraph,
                                              categoryName, exampleIndex, eI,
                                              eJ)
                        ], outfile)
                        exampleIndex += 1
                    self.exampleStats.endExample()

                    # define reverse
                    if self.styles["entities"]:
                        categoryName = self.getCategoryName(
                            sentenceGraph, eJ, eI, True)
                        if goldGraph != None:
                            categoryName = self.getGoldCategoryName(
                                goldGraph, entityToGold, eJ, eI, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(
                            sentenceGraph, tJ, tI, True)
                    # make reverse
                    self.exampleStats.beginExample(categoryName)
                    makeExample = True
                    if self.styles[
                            "genia_limits"] and not self.isPotentialGeniaInteraction(
                                eJ, eI):
                        makeExample = False
                        self.exampleStats.filter("genia_limits")
                    if self.styles["genia_task1"] and (
                            eI.get("type") == "Entity"
                            or eJ.get("type") == "Entity"):
                        makeExample = False
                        self.exampleStats.filter("genia_task1")
                    if self.styles[
                            "rel_limits"] and not self.isPotentialRELInteraction(
                                eJ, eI):
                        makeExample = False
                        self.exampleStats.filter("rel_limits")
                    if self.styles[
                            "co_limits"] and not self.isPotentialCOInteraction(
                                eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("co_limits")
                    if self.styles[
                            "bb_limits"] and not self.isPotentialBBInteraction(
                                eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("bb_limits")
                        if categoryName != "neg":
                            self.exampleStats.filter("bb_limits(" +
                                                     categoryName + ":" +
                                                     eJ.get("type") + "/" +
                                                     eI.get("type") + ")")
                    if self.styles[
                            "bi_limits"] and not self.isPotentialBIInteraction(
                                eJ, eI, sentenceGraph, self.exampleStats):
                        makeExample = False
                        #self.exampleStats.filter("bi_limits")
                    if self.styles[
                            "epi_limits"] and not self.isPotentialEPIInteraction(
                                eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("epi_limits")
                    if self.styles[
                            "id_limits"] and not self.isPotentialIDInteraction(
                                eJ, eI, sentenceGraph):
                        makeExample = False
                        self.exampleStats.filter("id_limits")
#                    if self.styles["selftrain_limits"] and (eI.get("selftrain") == "False" or eJ.get("selftrain") == "False"):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_limits")
#                    if self.styles["selftrain_group"] and (eI.get("selftraingroup") not in self.selfTrainGroups or eJ.get("selftraingroup") not in self.selfTrainGroups):
#                        makeExample = False
#                        self.exampleStats.filter("selftrain_group")
                    if self.styles["pos_only"] and categoryName == "neg":
                        makeExample = False
                        self.exampleStats.filter("pos_only")
                    if makeExample:
                        #examples.append( self.buildExample(tJ, tI, paths, sentenceGraph, categoryName, exampleIndex, eJ, eI) )
                        ExampleUtils.appendExamples([
                            self.buildExample(tJ, tI, paths, sentenceGraph,
                                              categoryName, exampleIndex, eJ,
                                              eI)
                        ], outfile)
                        exampleIndex += 1
                    self.exampleStats.endExample()
                else:
                    if self.styles["entities"]:
                        categoryName = self.getCategoryName(
                            sentenceGraph, eI, eJ, False)
                    else:
                        categoryName = self.getCategoryNameFromTokens(
                            sentenceGraph, tI, tJ, False)
                    self.exampleStats.beginExample(categoryName)
                    forwardExample = self.buildExample(tI, tJ, paths,
                                                       sentenceGraph,
                                                       categoryName,
                                                       exampleIndex, eI, eJ)
                    if not self.styles["graph_kernel"]:
                        reverseExample = self.buildExample(
                            tJ, tI, paths, sentenceGraph, categoryName,
                            exampleIndex, eJ, eI)
                        forwardExample[2].update(reverseExample[2])
                    #examples.append(forwardExample)
                    ExampleUtils.appendExamples([forwardExample], outfile)
                    exampleIndex += 1
                    self.exampleStats.endExample()

        #return examples
        return exampleIndex

    def buildExample(self,
                     token1,
                     token2,
                     paths,
                     sentenceGraph,
                     categoryName,
                     exampleIndex,
                     entity1=None,
                     entity2=None):
        """
        Build a single directed example for the potential edge between token1 and token2
        """
        # dummy return for speed testing
        #return (sentenceGraph.getSentenceId()+".x"+str(exampleIndex),1,{},{})

        # define features
        features = {}
        if True:  #token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
            #if token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
            #    path = paths[token1][token2]
            #else:
            #    path = [token1, token2]
            if not self.styles["no_path"]:
                # directedPath reduces performance by 0.01 pp
                #directedPath = sentenceGraph.dependencyGraph.getPaths(token1, token2)
                #if len(directedPath) == 0:
                #    directedPath = sentenceGraph.dependencyGraph.getPaths(token2, token1)
                #    for dp in directedPath:
                #        dp.reverse()
                #if len(directedPath) == 0:
                #    path = paths.getPaths(token1, token2)
                #else:
                #    path = directedPath

                path = paths.getPaths(token1, token2)
                if len(path) > 0:
                    #if len(path) > 1:
                    #    print len(path)
                    path = path[0]
                    pathExists = True
                else:
                    path = [token1, token2]
                    pathExists = False
            else:
                path = [token1, token2]
                pathExists = False
            #print token1.get("id"), token2.get("id")
            assert (self.pathLengths == None)
            if self.pathLengths == None or len(path) - 1 in self.pathLengths:
                #                if not "no_ontology" in self.styles:
                #                    self.ontologyFeatureBuilder.setFeatureVector(features)
                #                    self.ontologyFeatureBuilder.buildOntologyFeaturesForPath(sentenceGraph, path)
                #                    self.ontologyFeatureBuilder.setFeatureVector(None)
                if self.styles["trigger_features"]:  # F 85.52 -> 85.55
                    self.triggerFeatureBuilder.setFeatureVector(features)
                    self.triggerFeatureBuilder.tag = "trg1_"
                    self.triggerFeatureBuilder.buildFeatures(token1)
                    self.triggerFeatureBuilder.tag = "trg2_"
                    self.triggerFeatureBuilder.buildFeatures(token2)
                    self.triggerFeatureBuilder.setFeatureVector(None)
                # REL features
                if self.styles["rel_features"] and not self.styles["no_task"]:
                    self.relFeatureBuilder.setFeatureVector(features)
                    self.relFeatureBuilder.tag = "rel1_"
                    self.relFeatureBuilder.buildAllFeatures(
                        sentenceGraph.tokens,
                        sentenceGraph.tokens.index(token1))
                    self.relFeatureBuilder.tag = "rel2_"
                    self.relFeatureBuilder.buildAllFeatures(
                        sentenceGraph.tokens,
                        sentenceGraph.tokens.index(token2))
                    self.relFeatureBuilder.setFeatureVector(None)
                if self.styles[
                        "bacteria_renaming"] and not self.styles["no_task"]:
                    self.bacteriaRenamingFeatureBuilder.setFeatureVector(
                        features)
                    self.bacteriaRenamingFeatureBuilder.buildPairFeatures(
                        entity1, entity2)
                    #self.bacteriaRenamingFeatureBuilder.buildSubstringFeatures(entity1, entity2) # decreases perf. 74.76 -> 72.41
                    self.bacteriaRenamingFeatureBuilder.setFeatureVector(None)
                if self.styles["co_limits"] and not self.styles["no_task"]:
                    e1Offset = Range.charOffsetToSingleTuple(
                        entity1.get("charOffset"))
                    e2Offset = Range.charOffsetToSingleTuple(
                        entity2.get("charOffset"))
                    if Range.contains(e1Offset, e2Offset):
                        features[self.featureSet.getId("e1_contains_e2")] = 1
                        if entity2.get("isName") == "True":
                            features[self.featureSet.getId(
                                "e1_contains_e2name")] = 1
                    if Range.contains(e2Offset, e1Offset):
                        features[self.featureSet.getId("e2_contains_e1")] = 1
                        if entity1.get("isName") == "True":
                            features[self.featureSet.getId(
                                "e2_contains_e1name")] = 1
                if self.styles["ddi_features"]:
                    self.drugFeatureBuilder.setFeatureVector(features)
                    self.drugFeatureBuilder.tag = "ddi_"
                    self.drugFeatureBuilder.buildPairFeatures(entity1, entity2)
                    if self.styles["ddi_mtmx"]:
                        self.drugFeatureBuilder.buildMTMXFeatures(
                            entity1, entity2)
                    self.drugFeatureBuilder.setFeatureVector(None)
                #if "graph_kernel" in self.styles or not "no_dependency" in self.styles:
                #    #print "Getting edges"
                #    if token1 != token2 and pathExists:
                #        #print "g1"
                #        edges = self.multiEdgeFeatureBuilder.getEdges(sentenceGraph.dependencyGraph, path)
                #        #print "g2"
                #    else:
                #        edges = None
                if self.styles["graph_kernel"]:
                    self.graphKernelFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    self.graphKernelFeatureBuilder.buildGraphKernelFeatures(
                        sentenceGraph, path)
                    self.graphKernelFeatureBuilder.setFeatureVector(None)
                if self.styles["entity_type"]:
                    features[self.featureSet.getId("e1_" +
                                                   entity1.get("type"))] = 1
                    features[self.featureSet.getId("e2_" +
                                                   entity2.get("type"))] = 1
                    features[self.featureSet.getId("distance_" +
                                                   str(len(path)))] = 1
                if not self.styles["no_dependency"]:
                    #print "Dep features"
                    self.multiEdgeFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    #self.multiEdgeFeatureBuilder.buildStructureFeatures(sentenceGraph, paths) # remove for fast
                    if not self.styles["disable_entity_features"]:
                        self.multiEdgeFeatureBuilder.buildEntityFeatures(
                            sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildPathLengthFeatures(path)
                    if not self.styles["disable_terminus_features"]:
                        self.multiEdgeFeatureBuilder.buildTerminusTokenFeatures(
                            path, sentenceGraph)  # remove for fast
                    if not self.styles["disable_single_element_features"]:
                        self.multiEdgeFeatureBuilder.buildSingleElementFeatures(
                            path, sentenceGraph)
                    if not self.styles["disable_ngram_features"]:
                        #print "NGrams"
                        self.multiEdgeFeatureBuilder.buildPathGrams(
                            2, path, sentenceGraph)  # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(
                            3, path, sentenceGraph)  # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(
                            4, path, sentenceGraph)  # remove for fast
                    #self.buildEdgeCombinations(path, edges, sentenceGraph, features) # remove for fast
                    #if edges != None:
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[0], edges[0][1]+edges[1][0], "t1", sentenceGraph) # remove for fast
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[-1], edges[len(path)-1][len(path)-2]+edges[len(path)-2][len(path)-1], "t2", sentenceGraph) # remove for fast
                    if not self.styles["disable_path_edge_features"]:
                        self.multiEdgeFeatureBuilder.buildPathEdgeFeatures(
                            path, sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildSentenceFeatures(
                        sentenceGraph)
                    self.multiEdgeFeatureBuilder.setFeatureVector(None)
                if self.styles["nodalida"]:
                    self.nodalidaFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    shortestPaths = self.nodalidaFeatureBuilder.buildShortestPaths(
                        sentenceGraph.dependencyGraph, path)
                    print shortestPaths
                    if len(shortestPaths) > 0:
                        self.nodalidaFeatureBuilder.buildNGrams(
                            shortestPaths, sentenceGraph)
                    self.nodalidaFeatureBuilder.setFeatureVector(None)
                if not self.styles["no_linear"]:
                    self.tokenFeatureBuilder.setFeatureVector(features)
                    for i in range(len(sentenceGraph.tokens)):
                        if sentenceGraph.tokens[i] == token1:
                            token1Index = i
                        if sentenceGraph.tokens[i] == token2:
                            token2Index = i
                    linearPreTag = "linfw_"
                    if token1Index > token2Index:
                        token1Index, token2Index = token2Index, token1Index
                        linearPreTag = "linrv_"
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(
                        token1Index, sentenceGraph, 2, 2, preTag="linTok1")
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(
                        token2Index, sentenceGraph, 2, 2, preTag="linTok2")
                    # Before, middle, after
                    #                self.tokenFeatureBuilder.buildTokenGrams(0, token1Index-1, sentenceGraph, "bf")
                    #                self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, "bw")
                    #                self.tokenFeatureBuilder.buildTokenGrams(token2Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, "af")
                    # before-middle, middle, middle-after
                    #                    self.tokenFeatureBuilder.buildTokenGrams(0, token2Index-1, sentenceGraph, linearPreTag+"bf", max=2)
                    #                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, linearPreTag+"bw", max=2)
                    #                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, linearPreTag+"af", max=2)
                    self.tokenFeatureBuilder.setFeatureVector(None)
                if self.styles["random"]:
                    self.randomFeatureBuilder.setFeatureVector(features)
                    self.randomFeatureBuilder.buildRandomFeatures(100, 0.01)
                    self.randomFeatureBuilder.setFeatureVector(None)
                if self.styles["genia_limits"] and not self.styles["no_task"]:
                    e1Type = entity1.get("type")
                    e2Type = entity2.get("type")
                    assert (entity1.get("isName") == "False")
                    if entity2.get("isName") == "True":
                        features[self.featureSet.getId(
                            "GENIA_target_protein")] = 1
                    else:
                        features[self.featureSet.getId(
                            "GENIA_nested_event")] = 1
                    if e1Type.find(
                            "egulation"
                    ) != -1:  # leave r out to avoid problems with capitalization
                        if entity2.get("isName") == "True":
                            features[self.featureSet.getId(
                                "GENIA_regulation_of_protein")] = 1
                        else:
                            features[self.featureSet.getId(
                                "GENIA_regulation_of_event")] = 1
                if self.styles["bi_limits"]:
                    # Make features based on entity types
                    e1Type = entity1.get("type")
                    e2Type = entity2.get("type")
                    e1SuperType = str(self.getBISuperType(e1Type))
                    e2SuperType = str(self.getBISuperType(e2Type))
                    features[self.featureSet.getId("BI_e1_" + e1Type)] = 1
                    features[self.featureSet.getId("BI_e2_" + e2Type)] = 1
                    features[self.featureSet.getId("BI_e1sup_" +
                                                   e1SuperType)] = 1
                    features[self.featureSet.getId("BI_e2sup_" +
                                                   e2SuperType)] = 1
                    features[self.featureSet.getId("BI_e1e2_" + e1Type + "_" +
                                                   e2Type)] = 1
                    features[self.featureSet.getId("BI_e1e2sup_" +
                                                   e1SuperType + "_" +
                                                   e2SuperType)] = 1
                if self.styles["evex"]:
                    self.evexFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    self.evexFeatureBuilder.buildEdgeFeatures(
                        entity1, entity2, token1, token2, path, sentenceGraph)
                    self.evexFeatureBuilder.setFeatureVector(None)
                if self.styles["giuliano"]:
                    self.giulianoFeatureBuilder.setFeatureVector(
                        features, entity1, entity2)
                    self.giulianoFeatureBuilder.buildEdgeFeatures(
                        entity1, entity2, token1, token2, path, sentenceGraph)
                    self.giulianoFeatureBuilder.setFeatureVector(None)
            else:
                features[self.featureSet.getId("always_negative")] = 1
                if self.styles["subset"]:
                    features[self.featureSet.getId("out_of_scope")] = 1
        else:
            features[self.featureSet.getId("always_negative")] = 1
            if self.styles["subset"]:
                features[self.featureSet.getId("out_of_scope")] = 1
            path = [token1, token2]
        # define extra attributes
        #if int(path[0].get("id").split("_")[-1]) < int(path[-1].get("id").split("_")[-1]):
        if int(path[0].get("charOffset").split("-")[0]) < int(
                path[-1].get("charOffset").split("-")[0]):
            #extra = {"xtype":"edge","type":"i","t1":path[0],"t2":path[-1]}
            extra = {
                "xtype": "edge",
                "type": "i",
                "t1": path[0].get("id"),
                "t2": path[-1].get("id")
            }
            extra["deprev"] = False
        else:
            #extra = {"xtype":"edge","type":"i","t1":path[-1],"t2":path[0]}
            extra = {
                "xtype": "edge",
                "type": "i",
                "t1": path[-1].get("id"),
                "t2": path[0].get("id")
            }
            extra["deprev"] = True
        if entity1 != None:
            #extra["e1"] = entity1
            extra["e1"] = entity1.get("id")
            if sentenceGraph.mergedEntityToDuplicates != None:
                #extra["e1GoldIds"] = mergedEntityIds[entity1]
                extra["e1DuplicateIds"] = ",".join([
                    x.get("id")
                    for x in sentenceGraph.mergedEntityToDuplicates[entity1]
                ])
        if entity2 != None:
            #extra["e2"] = entity2
            extra["e2"] = entity2.get("id")
            if sentenceGraph.mergedEntityToDuplicates != None:
                extra["e2DuplicateIds"] = ",".join([
                    x.get("id")
                    for x in sentenceGraph.mergedEntityToDuplicates[entity2]
                ])
                #extra["e2GoldIds"] = mergedEntityIds[entity2]
        extra["categoryName"] = categoryName
        if self.styles["bacteria_renaming"]:
            if entity1.get("text") != None and entity1.get("text") != "":
                extra["e1t"] = entity1.get("text").replace(" ", "---").replace(
                    ":", "-COL-")
            if entity2.get("text") != None and entity2.get("text") != "":
                extra["e2t"] = entity2.get("text").replace(" ", "---").replace(
                    ":", "-COL-")
        sentenceOrigId = sentenceGraph.sentenceElement.get("origId")
        if sentenceOrigId != None:
            extra["SOID"] = sentenceOrigId
        # make example
        if self.styles["binary"]:
            if categoryName != "neg":
                category = 1
            else:
                category = -1
            categoryName = "i"
        else:
            category = self.classSet.getId(categoryName)

        # NOTE: temporarily disable for replicating 110310 experiment
        #features[self.featureSet.getId("extra_constant")] = 1
        return (sentenceGraph.getSentenceId() + ".x" + str(exampleIndex),
                category, features, extra)
class AsymmetricEventExampleBuilder(ExampleBuilder):
    def __init__(self, style=["typed","directed"], length=None, types=[], featureSet=None, classSet=None):
        if featureSet == None:
            featureSet = IdSet()
        if classSet == None:
            classSet = IdSet(1)
        else:
            classSet = classSet
        assert( classSet.getId("neg") == 1 )
        
        ExampleBuilder.__init__(self, classSet=classSet, featureSet=featureSet)
        if style.find(",") != -1:
            style = style.split(",")
        self.styles = style
        
        self.negFrac = None
        self.posPairGaz = POSPairGazetteer()
        for s in style:
            if s.find("negFrac") != -1:      
                self.negFrac = float(s.split("_")[-1])
                print >> sys.stderr, "Downsampling negatives to", self.negFrac
                self.negRand = random.Random(15)
            elif s.find("posPairGaz") != -1:
                self.posPairGaz = POSPairGazetteer(loadFrom=s.split("_", 1)[-1])
        
        self.multiEdgeFeatureBuilder = MultiEdgeFeatureBuilder(self.featureSet)
        self.triggerFeatureBuilder = TriggerFeatureBuilder(self.featureSet)
        if "graph_kernel" in self.styles:
            from FeatureBuilders.GraphKernelFeatureBuilder import GraphKernelFeatureBuilder
            self.graphKernelFeatureBuilder = GraphKernelFeatureBuilder(self.featureSet)
        if "noAnnType" in self.styles:
            self.multiEdgeFeatureBuilder.noAnnType = True
        if "noMasking" in self.styles:
            self.multiEdgeFeatureBuilder.maskNamedEntities = False
        if "maxFeatures" in self.styles:
            self.multiEdgeFeatureBuilder.maximum = True
        self.tokenFeatureBuilder = TokenFeatureBuilder(self.featureSet)
        if "ontology" in self.styles:
            self.multiEdgeFeatureBuilder.ontologyFeatureBuilder = BioInferOntologyFeatureBuilder(self.featureSet)
        if "nodalida" in self.styles:
            self.nodalidaFeatureBuilder = NodalidaFeatureBuilder(self.featureSet)
        #IF LOCAL
        if "bioinfer_limits" in self.styles:
            self.bioinferOntologies = OntologyUtils.getBioInferTempOntology()
            #self.bioinferOntologies = OntologyUtils.loadOntologies(OntologyUtils.g_bioInferFileName)
        #ENDIF
        self.pathLengths = length
        assert(self.pathLengths == None)
        self.types = types
        if "random" in self.styles:
            from FeatureBuilders.RandomFeatureBuilder import RandomFeatureBuilder
            self.randomFeatureBuilder = RandomFeatureBuilder(self.featureSet)

        #self.outFile = open("exampleTempFile.txt","wt")

    @classmethod
    def run(cls, input, output, parse, tokenization, style, idFileTag=None):
        classSet, featureSet = cls.getIdSets(idFileTag)
        if style != None:
            e = cls(style=style, classSet=classSet, featureSet=featureSet)
        else:
            e = cls(classSet=classSet, featureSet=featureSet)
        sentences = cls.getSentences(input, parse, tokenization)
        e.buildExamplesForSentences(sentences, output, idFileTag)
        if "printClassIds" in e.styles:
            print >> sys.stderr, e.classSet.Ids
  
    def definePredictedValueRange(self, sentences, elementName):
        self.multiEdgeFeatureBuilder.definePredictedValueRange(sentences, elementName)                        
    
    def getPredictedValueRange(self):
        return self.multiEdgeFeatureBuilder.predictedRange
    
    def filterEdgesByType(self, edges, typesToInclude):
        if len(typesToInclude) == 0:
            return edges
        edgesToKeep = []
        for edge in edges:
            if edge.get("type") in typesToInclude:
                edgesToKeep.append(edge)
        return edgesToKeep
    
    def getCategoryNameFromTokens(self, sentenceGraph, t1, t2, directed=True):
        types = set()
        themeE1Types = set()
        intEdges = []
        if sentenceGraph.interactionGraph.has_edge(t1, t2):
            intEdges = sentenceGraph.interactionGraph.get_edge_data(t1, t2, default={})
            # NOTE: Only works if keys are ordered integers
            for i in range(len(intEdges)):
                types.add(intEdges[i]["element"].get("type"))

#        if (not directed) and sentenceGraph.interactionGraph.has_edge(t2, t1):
#            intEdgesReverse = sentenceGraph.interactionGraph.get_edge(t2, t1, default={})
#            # NOTE: Only works if keys are ordered integers
#            for i in range(len(intEdgesReverse)):
#                intElement = intEdgesReverse[i]["element"]
#                intType = intElement.get("type")
#                types.add(intType)
#            intEdges.extend(intEdgesReverse)

        for i in range(len(intEdges)):
            intElement = intEdges[i]["element"]
            intType = intElement.get("type")
            if intType == "Theme":
                e1Entity = sentenceGraph.entitiesById[intElement.get("e1")]
                themeE1Types.add(e1Entity.get("type"))
            #types.add(intType)
        
        if len(themeE1Types) != 0:
            themeE1Types = list(themeE1Types)
            themeE1Types.sort()
            categoryName = ""
            for name in themeE1Types:
                if categoryName != "":
                    categoryName += "---"
                categoryName += name
            return categoryName            
        else:
            types = list(types)
            types.sort()
            categoryName = ""
            for name in types:
                if categoryName != "":
                    categoryName += "---"
                categoryName += name
            if categoryName != "":
                return categoryName
            else:
                return "neg"
        
    def getCategoryName(self, sentenceGraph, e1, e2, directed=True):
        interactions = sentenceGraph.getInteractions(e1, e2)
        if not directed:
            interactions.extend(sentenceGraph.getInteractions(e2, e1))
        
        types = set()
        for interaction in interactions:
            types.add(interaction.attrib["type"])
        types = list(types)
        types.sort()
        categoryName = ""
        for name in types:
            if categoryName != "":
                categoryName += "---"
            categoryName += name
        if categoryName != "":
            return categoryName
        else:
            return "neg"           
    
    def preProcessExamples(self, allExamples):
        # Duplicates cannot be removed here, as they should only be removed from the training set. This is done
        # in the classifier.
#        if "no_duplicates" in self.styles:
#            count = len(allExamples)
#            print >> sys.stderr, " Removing duplicates,", 
#            allExamples = ExampleUtils.removeDuplicates(allExamples)
#            print >> sys.stderr, "removed", count - len(allExamples)
        if "normalize" in self.styles:
            print >> sys.stderr, " Normalizing feature vectors"
            ExampleUtils.normalizeFeatureVectors(allExamples)
        return allExamples   
    
    def isPotentialGeniaInteraction(self, e1, e2):
        if e1.get("isName") == "True":
            return False
        else:
            return True
    
    #IF LOCAL
    def getBioInferParentType(self, eType):
        if eType == "Physical_entity" or OntologyUtils.hasParent(eType, "Physical_entity", self.bioinferOntologies):
            return "Physical"
        elif eType == "Property_entity" or OntologyUtils.hasParent(eType, "Property_entity", self.bioinferOntologies):
            return "Property"
        elif OntologyUtils.hasParent(eType, "Relationship", self.bioinferOntologies):
            return "Process"
        else:
            assert False, eType
        
#        if self.bioinferOntologies["Entity"].has_key(eType):
#            if OntologyUtils.hasParent(eType, "Physical_entity", self.bioinferOntologies):
#                assert not OntologyUtils.hasParent(eType, "Property_entity", self.bioinferOntologies), eType
#                return "Physical"
#            else:
#                assert OntologyUtils.hasParent(eType, "Property_entity", self.bioinferOntologies), eType
#                return "Property"
#                
#        else:
#            assert self.bioinferOntologies.has_key(eType), eType
#            #assert OntologyUtils.hasParent(eType, "Process_entity", self.bioinferOntologies["Relationship"]), eType
#            return "Process"
    
    def isPotentialBioInferInteraction(self, e1, e2, categoryName):
        e1Type = self.getBioInferParentType(e1.get("type"))
        e2Type = self.getBioInferParentType(e2.get("type"))
        if e1Type == "Process" or e1Type == "Property":
            return True
        elif e1Type == "Physical" and e2Type == "Physical":
            return True
        elif e1Type == "Physical" and e2Type == "Process": # hack
            return True
        else:
            assert(categoryName == "neg"), categoryName + " category for " + e1Type + " and " + e2Type
            return False
    #ENDIF
    
    def nxMultiDiGraphToUndirected(self, graph):
        undirected = NX10.MultiGraph(name=graph.name)
        undirected.add_nodes_from(graph)
        undirected.add_edges_from(graph.edges_iter())
        return undirected
            
    def buildExamples(self, sentenceGraph):
        examples = []
        exampleIndex = 0
        
        clearGraph = sentenceGraph.getCleared()
        
        #undirected = sentenceGraph.getUndirectedDependencyGraph()
        undirected = self.nxMultiDiGraphToUndirected(sentenceGraph.dependencyGraph)
        ##undirected = sentenceGraph.dependencyGraph.to_undirected()
        ###undirected = NX10.MultiGraph(sentenceGraph.dependencyGraph) This didn't work
        paths = NX10.all_pairs_shortest_path(undirected, cutoff=999)
        
        self.triggerFeatureBuilder.initSentence(clearGraph)
        
        # Generate examples based on interactions between entities or interactions between tokens
        if "entities" in self.styles:
            loopRange = len(sentenceGraph.entities)
        else:
            loopRange = len(sentenceGraph.tokens)
        #for i in range(loopRange-1):
        for i in range(loopRange): # allow self-interactions
            #for j in range(i+1,loopRange):
            for j in range(i,loopRange): # allow self-interactions
                eI = None
                eJ = None
                if "entities" in self.styles:
                    eI = sentenceGraph.entities[i]
                    eJ = sentenceGraph.entities[j]
                    tI = sentenceGraph.entityHeadTokenByEntity[eI]
                    tJ = sentenceGraph.entityHeadTokenByEntity[eJ]
                    #if "no_ne_interactions" in self.styles and eI.get("isName") == "True" and eJ.get("isName") == "True":
                    #    continue
                    if eI.get("type") == "neg" or eJ.get("type") == "neg":
                        continue
                else:
                    tI = sentenceGraph.tokens[i]
                    tJ = sentenceGraph.tokens[j]
#                # only consider paths between entities (NOTE! entities, not only named entities)
#                if "headsOnly" in self.styles:
#                    if (len(sentenceGraph.tokenIsEntityHead[tI]) == 0) or (len(sentenceGraph.tokenIsEntityHead[tJ]) == 0):
#                        continue
                
                if "directed" in self.styles:
                    # define forward
                    if "entities" in self.styles:
                        categoryName = self.getCategoryName(sentenceGraph, eI, eJ, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(sentenceGraph, tI, tJ, True)
                    self.exampleStats.beginExample(categoryName)
                    if self.negFrac == None or categoryName != "neg" or (categoryName == "neg" and self.negRand.random() < self.negFrac):
                        makeExample = True
                        if ("genia_limits" in self.styles) and not self.isPotentialGeniaInteraction(eI, eJ):
                            makeExample = False
                            self.exampleStats.filter("genia_limits")
                        if self.posPairGaz.getNegFrac((tI.get("POS"), tJ.get("POS"))) == 1.0:
                            makeExample = False
                            self.exampleStats.filter("pos_pair")
                        if makeExample:
                            if not sentenceGraph.tokenIsName[tI]:
                                examples.append( self.buildExample(tI, tJ, paths, clearGraph, categoryName, exampleIndex, eI, eJ) )
                                exampleIndex += 1
                            else:
                                self.exampleStats.filter("genia_token_limits")
                    else:
                        self.exampleStats.filter("neg_frac")
                    self.exampleStats.endExample()
                    
                    # define reverse
                    if "entities" in self.styles:
                        categoryName = self.getCategoryName(sentenceGraph, eJ, eI, True)
                    else:
                        categoryName = self.getCategoryNameFromTokens(sentenceGraph, tJ, tI, True)
                    self.exampleStats.beginExample(categoryName)
                    if self.negFrac == None or categoryName != "neg" or (categoryName == "neg" and self.negRand.random() < self.negFrac):
                        makeExample = True
                        if ("genia_limits" in self.styles) and not self.isPotentialGeniaInteraction(eJ, eI):
                            makeExample = False
                            self.exampleStats.filter("genia_limits")
                        if ("bioinfer_limits" in self.styles) and not self.isPotentialBioInferInteraction(eJ, eI, categoryName):
                            makeExample = False
                            self.exampleStats.filter("bioinfer_limits")
                        if self.posPairGaz.getNegFrac((tJ.get("POS"), tI.get("POS"))) == 1.0:
                            makeExample = False
                            self.exampleStats.filter("pos_pair")
                        if makeExample:
                            if not sentenceGraph.tokenIsName[tJ]:
                                examples.append( self.buildExample(tJ, tI, paths, clearGraph, categoryName, exampleIndex, eJ, eI) )
                                exampleIndex += 1
                            else:
                                self.exampleStats.filter("genia_token_limits")
                    else:
                        self.exampleStats.filter("neg_frac")
                    self.exampleStats.endExample()
#                else:
#                    if "entities" in self.styles:
#                        categoryName = self.getCategoryName(sentenceGraph, eI, eJ, False)
#                    else:
#                        categoryName = self.getCategoryNameFromTokens(sentenceGraph, tI, tJ, False)
#                    forwardExample = self.buildExample(tI, tJ, paths, clearGraph, categoryName, exampleIndex, eI, eJ)
#                    if not "graph_kernel" in self.styles:
#                        reverseExample = self.buildExample(tJ, tI, paths, clearGraph, categoryName, exampleIndex, eJ, eI)
#                        forwardExample[2].update(reverseExample[2])
#                    examples.append(forwardExample)
#                    exampleIndex += 1
        
        return examples
    
    def buildExample(self, token1, token2, paths, sentenceGraph, categoryName, exampleIndex, entity1=None, entity2=None):
        # define features
        features = {}
        if True: #token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
            if token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
                path = paths[token1][token2]
            else:
                path = [token1, token2]
            assert(self.pathLengths == None)
            if self.pathLengths == None or len(path)-1 in self.pathLengths:
                if not "no_trigger":
                    self.triggerFeatureBuilder.setFeatureVector(self.features)
                    self.triggerFeatureBuilder.tag = "trg_t1_"
                    self.triggerFeatureBuilder.buildFeatures(eventToken)
                    self.triggerFeatureBuilder.tag = "trg_t2_"
                    self.triggerFeatureBuilder.buildFeatures(eventToken)
#                if not "no_ontology" in self.styles:
#                    self.ontologyFeatureBuilder.setFeatureVector(features)
#                    self.ontologyFeatureBuilder.buildOntologyFeaturesForPath(sentenceGraph, path)
#                    self.ontologyFeatureBuilder.setFeatureVector(None)
                if "graph_kernel" in self.styles or not "no_dependency" in self.styles:
                    if token1 != token2 and paths.has_key(token1) and paths[token1].has_key(token2):
                        edges = self.multiEdgeFeatureBuilder.getEdges(sentenceGraph.dependencyGraph, path)
                    else:
                        edges = None
                if "graph_kernel" in self.styles:
                    self.graphKernelFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    self.graphKernelFeatureBuilder.buildGraphKernelFeatures(sentenceGraph, path, edges)
                    self.graphKernelFeatureBuilder.setFeatureVector(None)
                if "entity_type" in self.styles:
                    features[self.featureSet.getId("e1_"+entity1.attrib["type"])] = 1
                    features[self.featureSet.getId("e2_"+entity2.attrib["type"])] = 1
                    features[self.featureSet.getId("distance_"+str(len(path)))] = 1
                if not "no_dependency" in self.styles:
                    if token1 == token2:
                        features[self.featureSet.getId("tokenSelfLoop")] = 1
                    
                    self.multiEdgeFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    #self.multiEdgeFeatureBuilder.buildStructureFeatures(sentenceGraph, paths) # remove for fast
                    if not "disable_entity_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildEntityFeatures(sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildPathLengthFeatures(path)
                    if not "disable_terminus_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildTerminusTokenFeatures(path, sentenceGraph) # remove for fast
                    if not "disable_single_element_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildSingleElementFeatures(path, edges, sentenceGraph)
                    if not "disable_ngram_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildPathGrams(2, path, edges, sentenceGraph) # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(3, path, edges, sentenceGraph) # remove for fast
                        self.multiEdgeFeatureBuilder.buildPathGrams(4, path, edges, sentenceGraph) # remove for fast
                    #self.buildEdgeCombinations(path, edges, sentenceGraph, features) # remove for fast
                    #if edges != None:
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[0], edges[0][1]+edges[1][0], "t1", sentenceGraph) # remove for fast
                    #    self.multiEdgeFeatureBuilder.buildTerminusFeatures(path[-1], edges[len(path)-1][len(path)-2]+edges[len(path)-2][len(path)-1], "t2", sentenceGraph) # remove for fast
                    if not "disable_path_edge_features" in self.styles:
                        self.multiEdgeFeatureBuilder.buildPathEdgeFeatures(path, edges, sentenceGraph)
                    self.multiEdgeFeatureBuilder.buildSentenceFeatures(sentenceGraph)
                    self.multiEdgeFeatureBuilder.setFeatureVector(None)
                if "nodalida" in self.styles:
                    self.nodalidaFeatureBuilder.setFeatureVector(features, entity1, entity2)
                    shortestPaths = self.nodalidaFeatureBuilder.buildShortestPaths(sentenceGraph.dependencyGraph, path)
                    print shortestPaths
                    if len(shortestPaths) > 0:
                        self.nodalidaFeatureBuilder.buildNGrams(shortestPaths, sentenceGraph)
                    self.nodalidaFeatureBuilder.setFeatureVector(None)
                if not "no_linear" in self.styles:
                    self.tokenFeatureBuilder.setFeatureVector(features)
                    for i in range(len(sentenceGraph.tokens)):
                        if sentenceGraph.tokens[i] == token1:
                            token1Index = i
                        if sentenceGraph.tokens[i] == token2:
                            token2Index = i
                    linearPreTag = "linfw_"
                    if token1Index > token2Index: 
                        token1Index, token2Index = token2Index, token1Index
                        linearPreTag = "linrv_"
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(token1Index, sentenceGraph, 2, 2, preTag="linTok1")
                    self.tokenFeatureBuilder.buildLinearOrderFeatures(token2Index, sentenceGraph, 2, 2, preTag="linTok2")
                    # Before, middle, after
    #                self.tokenFeatureBuilder.buildTokenGrams(0, token1Index-1, sentenceGraph, "bf")
    #                self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, "bw")
    #                self.tokenFeatureBuilder.buildTokenGrams(token2Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, "af")
                    # before-middle, middle, middle-after
#                    self.tokenFeatureBuilder.buildTokenGrams(0, token2Index-1, sentenceGraph, linearPreTag+"bf", max=2)
#                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, token2Index-1, sentenceGraph, linearPreTag+"bw", max=2)
#                    self.tokenFeatureBuilder.buildTokenGrams(token1Index+1, len(sentenceGraph.tokens)-1, sentenceGraph, linearPreTag+"af", max=2)
                    self.tokenFeatureBuilder.setFeatureVector(None)
                if "random" in self.styles:
                    self.randomFeatureBuilder.setFeatureVector(features)
                    self.randomFeatureBuilder.buildRandomFeatures(100, 0.01)
                    self.randomFeatureBuilder.setFeatureVector(None)
                if "genia_limits" in self.styles:
                    e1Type = entity1.get("type")
                    e2Type = entity2.get("type")
                    assert(entity1.get("isName") == "False")
                    if entity2.get("isName") == "True":
                        features[self.featureSet.getId("GENIA_target_protein")] = 1
                    else:
                        features[self.featureSet.getId("GENIA_nested_event")] = 1
                    if e1Type.find("egulation") != -1: # leave r out to avoid problems with capitalization
                        if entity2.get("isName") == "True":
                            features[self.featureSet.getId("GENIA_regulation_of_protein")] = 1
                        else:
                            features[self.featureSet.getId("GENIA_regulation_of_event")] = 1
            else:
                features[self.featureSet.getId("always_negative")] = 1
                if "subset" in self.styles:
                    features[self.featureSet.getId("out_of_scope")] = 1
        else:
            features[self.featureSet.getId("always_negative")] = 1
            if "subset" in self.styles:
                features[self.featureSet.getId("out_of_scope")] = 1
            path = [token1, token2]
        
        self.triggerFeatureBuilder.tag = ""
        self.triggerFeatureBuilder.setFeatureVector(None)
        
        # define extra attributes
#        if int(path[0].attrib["id"].split("_")[-1]) < int(path[-1].attrib["id"].split("_")[-1]):
#            #extra = {"xtype":"edge","type":"i","t1":path[0],"t2":path[-1]}
#            extra = {"xtype":"asym","type":"i","t1":path[0].get("id"),"t2":path[-1].get("id")}
#            extra["deprev"] = False
#        else:
#            #extra = {"xtype":"edge","type":"i","t1":path[-1],"t2":path[0]}
#            extra = {"xtype":"asym","type":"i","t1":path[-1].get("id"),"t2":path[0].get("id")}
#            extra["deprev"] = True

        extra = {"xtype":"asym","type":"i","t1":token1.get("id"),"t2":token2.get("id")}
        if entity1 != None:
            #extra["e1"] = entity1
            extra["e1"] = entity1.get("id")
        if entity2 != None:
            #extra["e2"] = entity2
            extra["e2"] = entity2.get("id")
        extra["categoryName"] = categoryName
        sentenceOrigId = sentenceGraph.sentenceElement.get("origId")
        if sentenceOrigId != None:
            extra["SOID"] = sentenceOrigId       
        # make example
        if "binary" in self.styles:
            if categoryName != "neg":
                category = 1
            else:
                category = -1
            categoryName = "i"
        else:
            category = self.classSet.getId(categoryName)
        
        return (sentenceGraph.getSentenceId()+".x"+str(exampleIndex),category,features,extra)