Exemple #1
0
def test_model_extend():
    ev1 = Evidence(pmid='1234', text='abcd', source_api='x')
    ev2 = Evidence(pmid='1234', text='abcde', source_api='x')
    ev3 = Evidence(pmid='1234', text='abcd', source_api='x')
    indra_sts = [Phosphorylation(None, Agent('a'), evidence=ev) for ev in
                 [ev1, ev2, ev3]]
    emmaa_sts = [EmmaaStatement(st, datetime.datetime.now(), []) for st in
                 indra_sts]
    em = EmmaaModel('x', {'search_terms': [], 'ndex': {'network': None}})
    em.add_statements([emmaa_sts[0]])
    em.extend_unique(emmaa_sts[1:])
    assert len(em.stmts) == 2
    stmt = EmmaaStatement(Phosphorylation(None, Agent('b'), evidence=ev1),
                          datetime.datetime.now(), [])
    em.extend_unique([stmt])
    assert len(em.stmts) == 3
Exemple #2
0
def test_filter_relevance():
    config_dict = {
        'ndex': {
            'network': 'a08479d1-24ce-11e9-bb6a-0ac135e8bacf'
        },
        'search_terms': [{
            'db_refs': {
                'HGNC': '20974'
            },
            'name': 'MAPK1',
            'search_term': 'MAPK1',
            'type': 'gene'
        }]
    }
    indra_stmts = \
        [Activation(Agent('BRAF', db_refs={'HGNC': '20974'}),
                    Agent('MAP2K1'),
                    evidence=[Evidence(text='BRAF activates MAP2K1.',
                                       source_api='assertion')]),
         Activation(Agent('MAP2K1',
                          activity=ActivityCondition('activity', True)),
                    Agent('MAPK1'),
                    evidence=[Evidence(text='Active MAP2K1 activates '
                                            'MAPK1.',
                                       source_api='assertion')])
         ]
    st = SearchTerm('gene', 'MAP2K1', db_refs={}, search_term='MAP2K1')
    emmaa_stmts = [
        EmmaaStatement(stmt, datetime.datetime.now(), [st])
        for stmt in indra_stmts
    ]

    # Try no filter first
    emmaa_model = EmmaaModel('test', config_dict)
    emmaa_model.extend_unique(emmaa_stmts)
    emmaa_model.run_assembly()
    assert len(emmaa_model.assembled_stmts) == 2, emmaa_model.assembled_stmts

    # Next do a prior_one filter
    config_dict['assembly'] = {'filter_relevance': 'prior_one'}
    emmaa_model = EmmaaModel('test', config_dict)
    emmaa_model.extend_unique(emmaa_stmts)
    emmaa_model.run_assembly()
    assert len(emmaa_model.assembled_stmts) == 1, emmaa_model.assembled_stmts
    assert emmaa_model.assembled_stmts[0].obj.name == 'MAPK1'

    # Next do a prior_all filter
    config_dict['assembly'] = {'filter_relevance': 'prior_all'}
    emmaa_model = EmmaaModel('test', config_dict)
    emmaa_model.extend_unique(emmaa_stmts)
    emmaa_model.run_assembly()
    assert len(emmaa_model.assembled_stmts) == 0