def test_validation_failure_for_empty_input_file(self):
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(lines=[])
with self.assertRaisesRegexp(ValueError,
'Input file .* is empty.'):
pipeline_common._get_all_patterns(input_pattern=None,
input_file=filename)
def test_write_headers(self):
header = _get_vcf_header_from_lines(self.lines)
with temp_dir.TempDir() as tempdir:
tempfile = tempdir.create_temp_file(suffix='.vcf')
header_fn = WriteVcfHeaderFn(tempfile)
header_fn.process(header)
self._assert_file_contents_equal(tempfile, self.lines)
def test_config_failed_missing_partition_name(self):
tempdir = temp_dir.TempDir()
missing_par_name = [
'- partition:',
' regions:',
' - "chr1:0-1,000,000"',
]
with self.assertRaisesRegexp(
ValueError,
'Each partition must have partition_name field.'):
_ = variant_partition.VariantPartition(
tempdir.create_temp_file(suffix='.yaml',
lines='\n'.join(missing_par_name)))
empty_par_name = [
'- partition:',
' partition_name: " "',
' regions:',
' - "chr1:0-1,000,000"',
]
with self.assertRaisesRegexp(
ValueError,
'Partition name can not be empty string.'):
_ = variant_partition.VariantPartition(
tempdir.create_temp_file(suffix='.yaml',
lines='\n'.join(empty_par_name)))
def test_pipeline_read_all_file_pattern(self):
with temp_dir.TempDir() as tempdir:
headers_1 = [self.lines[1], self.lines[-1]]
headers_2 = [self.lines[2], self.lines[3], self.lines[-1]]
headers_3 = [self.lines[4], self.lines[-1]]
file_name_1 = tempdir.create_temp_file(suffix='.vcf',
lines=headers_1)
file_name_2 = tempdir.create_temp_file(suffix='.vcf',
lines=headers_2)
file_name_3 = tempdir.create_temp_file(suffix='.vcf',
lines=headers_3)
pipeline = TestPipeline()
pcoll = (pipeline
| 'Create' >> beam.Create(
[os.path.join(tempdir.get_path(), '*.vcf')])
| 'ReadHeaders' >> ReadAllVcfHeaders())
expected = [
_get_vcf_header_from_lines(h, file_name=file_name)
for h, file_name in [(
headers_1,
file_name_1), (headers_2,
file_name_2), (headers_3, file_name_3)]
]
assert_that(pcoll, asserts.header_vars_equal(expected))
pipeline.run()
def test_pipeline_read_all_file_pattern(self):
with temp_dir.TempDir() as tempdir:
lines_1 = self.headers[1:2] + self.headers[-1:] + self.records[:2]
lines_2 = self.headers[2:4] + self.headers[-1:] + self.records[2:4]
lines_3 = self.headers[4:5] + self.headers[-1:] + self.records[4:]
file_name_1 = tempdir.create_temp_file(suffix='.vcf',
lines=lines_1)
file_name_2 = tempdir.create_temp_file(suffix='.vcf',
lines=lines_2)
file_name_3 = tempdir.create_temp_file(suffix='.vcf',
lines=lines_3)
pipeline = TestPipeline()
pcoll = pipeline | 'ReadHeaders' >> GetEstimates(
os.path.join(tempdir.get_path(), '*.vcf'))
pcoll = (pipeline
| 'Create' >> beam.Create(
[os.path.join(tempdir.get_path(), '*.vcf')])
| 'GetAllEstimates' >> GetAllEstimates())
expected = [
_get_estimate_from_lines(lines, file_name=file_name)
for lines, file_name in [(
lines_1, file_name_1), (lines_2,
file_name_2), (lines_3,
file_name_3)]
]
assert_that(pcoll, asserts.header_vars_equal(expected))
pipeline.run()
def test_config_failed_duplicate_residual_shard(self):
tempdir = temp_dir.TempDir()
duplicate_residual = [
'- output_table:',
' table_name_suffix: "all_remaining"',
' regions:',
' - "residual"',
' partition_range_end: 999999999',
'- output_table:',
' table_name_suffix: "chr01"',
' regions:',
' - "chr1"',
' partition_range_end: 999999999',
'- output_table:',
' table_name_suffix: "all_remaining_2"',
' regions:',
' - "residual"',
' partition_range_end: 999999999',
]
with self.assertRaisesRegex(
ValueError,
'Wrong sharding config file, there can be only one residual output*'
):
_ = variant_sharding.VariantSharding(
tempdir.create_temp_file(suffix='.yaml',
lines='\n'.join(duplicate_residual)))
def test_config_failed_duplicate_table_name(self):
tempdir = temp_dir.TempDir()
dup_table_name = [
'- output_table:',
' table_name_suffix: "duplicate_name"',
' regions:',
' - "chr1:0-1,000,000"',
' partition_range_end: 999999999',
'- output_table:',
' table_name_suffix: "all_remaining"',
' regions:',
' - "residual"',
' partition_range_end: 999999999',
'- output_table:',
' table_name_suffix: "duplicate_name"',
' regions:',
' - "chr1:1,000,000-2,000,000"',
' partition_range_end: 999999999',
]
with self.assertRaisesRegex(
ValueError,
'Wrong sharding config file, table name suffixes must be unique*'
):
_ = variant_sharding.VariantSharding(
tempdir.create_temp_file(suffix='.yaml',
lines='\n'.join(dup_table_name)))
def test_config_failed_missing_shard_name(self):
tempdir = temp_dir.TempDir()
missing_par_name = [
'- output_table:',
' regions:',
' - "chr1:0-1,000,000"',
' partition_range_end: 999999999',
]
with self.assertRaisesRegex(
ValueError,
'Wrong sharding config file, table_name_suffix field missing.'
):
_ = variant_sharding.VariantSharding(
tempdir.create_temp_file(suffix='.yaml',
lines='\n'.join(missing_par_name)))
empty_par_name = [
'- output_table:',
' table_name_suffix: " "',
' regions:',
' - "chr1:0-1,000,000"',
' partition_range_end: 999999999',
]
with self.assertRaisesRegex(
ValueError,
'Wrong sharding config file, table_name_suffix can not be empty.'
):
_ = variant_sharding.VariantSharding(
tempdir.create_temp_file(suffix='.yaml',
lines='\n'.join(empty_par_name)))
def _create_file_and_read_headers(self):
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(suffix='.vcf',
lines=self.lines)
headers = source_test_utils.read_from_source(
VcfHeaderSource(filename))
return headers[0]
def test_write_vcf_data_header(self):
lines = [
'##fileformat=VCFv4.2\n',
'##INFO=<ID=NS,Number=1,Type=Integer,Description="Number samples">\n',
'##INFO=<ID=AF,Number=A,Type=Float,Description="Allele Frequency">\n',
'##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">\n',
'##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="GQ">\n',
'#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT \n'
]
with temp_dir.TempDir() as tempdir:
representative_header = tempdir.create_temp_file(lines=lines)
file_path = filesystems.FileSystems.join(tempdir.get_path(),
'data_header')
bq_to_vcf._write_vcf_header_with_call_names(
['Sample 1', 'Sample 2'],
['#CHROM', 'POS', 'ID', 'REF', 'ALT'], representative_header,
file_path)
expected_content = [
'##fileformat=VCFv4.2\n',
'##INFO=<ID=NS,Number=1,Type=Integer,Description="Number samples">\n',
'##INFO=<ID=AF,Number=A,Type=Float,Description="Allele Frequency">\n',
'##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">\n',
'##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="GQ">\n',
'#CHROM\tPOS\tID\tREF\tALT\tSample 1\tSample 2\n'
]
with filesystems.FileSystems.open(file_path) as f:
content = f.readlines()
self.assertEqual(content, expected_content)
def test_write_to_shards(self):
with temp_dir.TempDir() as tempdir:
shards_writter = write_variants_to_shards._WriteVariantsToVCFShards(
tempdir.get_path(), 3)
variants = self._get_variants()
variant_lines = [
shards_writter._coder.encode(v).strip('\n') for v in variants
]
shards_writter._write_variant_lines_to_vcf_shard(variant_lines)
expected_content = [
'\t'.join([
'#CHROM', 'POS', 'ID', 'REF', 'ALT', 'QUAL', 'FILTER',
'INFO', 'FORMAT\n'
]), '\t'.join([
'19', '12', 'rs1', 'C', 'A,TT', '2', 'PASS',
'A1=some data;A2=data1,data2', '.\n'
]), '\t'.join([
'19', '12', 'rs1', 'C', 'A,TT', '20', 'q10',
'A1=some data2;A3=data3,data4', '.'
])
]
file_paths = []
for dirpath, _, filenames in os.walk(tempdir.get_path()):
for f in filenames:
file_paths.append(os.path.abspath(os.path.join(dirpath,
f)))
self.assertEqual(1, len(file_paths))
with filesystems.FileSystems.open(file_paths[0]) as f:
content = f.readlines()
self.assertEqual(content, expected_content)
def test_write_to_shards_pipeline(self):
with temp_dir.TempDir() as tempdir:
pipeline = TestPipeline()
_ = (pipeline
| Create(self._get_variants())
| 'WriteToShards' >> write_variants_to_shards.WriteToShards(
tempdir.get_path(), ['Sample 1', 'Sample 2']))
pipeline.run()
def test_print_estimates_to_file(self):
with temp_dir.TempDir() as tempdir:
file_path = os.path.join(tempdir.get_path(), 'test_file_name')
extract_input_size.print_estimates_to_file(1, 2, 3, 4, 5,
file_path)
with FileSystems.open(file_path) as f:
lines = f.readlines()
self.assertEqual([int(line.strip()) for line in lines],
[1, 2, 3, 4, 5])
def test_write_dataflow(self):
header = _get_vcf_header_from_lines(self.lines)
with temp_dir.TempDir() as tempdir:
tempfile = tempdir.create_temp_file(suffix='.vcf')
pipeline = TestPipeline()
pcoll = pipeline | beam.Create([header])
_ = pcoll | 'Write' >> WriteVcfHeaders(tempfile)
pipeline.run()
self._assert_file_contents_equal(tempfile, self.lines)
def test_get_mode_optimize_set(self):
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(lines=self.SAMPLE_LINES)
args = self._create_mock_args(input_pattern=None,
input_file=filename,
optimize_for_large_inputs=True)
self.assertEqual(self._get_pipeline_mode(args),
PipelineModes.LARGE)
def test_empty_file(self):
lines = []
with temp_dir.TempDir() as tempdir:
file_path = self._create_temp_vcf_file(lines, tempdir)
try:
vcf_header_parser.get_vcf_headers(file_path)
self.fail('Empty VCF file must throw an exception.')
except ValueError:
pass
def test_preprocess_no_conflicts(self):
with temp_dir.TempDir() as tempdir:
report_path = filesystems.FileSystems.join(
tempdir.get_path(), PreprocessTest._REPORT_NAME)
argv = [
'--input_pattern',
'gs://gcp-variant-transforms-testfiles/small_tests/valid-4.0.vcf',
'--report_path', report_path, '--report_all_conflicts'
]
vcf_to_bq_preprocess.run(argv)
assert filesystems.FileSystems.exists(report_path)
def test_write_vcf_data_header(self):
with temp_dir.TempDir() as tempdir:
file_path = filesystems.FileSystems.join(tempdir.get_path(),
'data_header')
bq_to_vcf._write_vcf_data_header(['Sample 1', 'Sample 2'],
['#CHROM', 'POS', 'ID', 'REF', 'ALT'],
file_path)
expected_content = '#CHROM\tPOS\tID\tREF\tALT\tSample 1\tSample 2\n'
with filesystems.FileSystems.open(file_path) as f:
content = f.readlines()
self.assertEqual(content, [expected_content])
def test_pipeline_read_file_headers(self):
headers = self.lines
self.lines = testdata_util.get_sample_vcf_file_lines()
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(suffix='.vcf', lines=self.lines)
pipeline = TestPipeline()
pcoll = pipeline | 'ReadHeaders' >> ReadVcfHeaders(filename)
assert_that(pcoll, equal_to([_get_vcf_header_from_lines(headers)]))
pipeline.run()
def test_get_mode_small_still_large(self):
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(lines=self.SAMPLE_LINES)
args = self._create_mock_args(input_pattern=None,
input_file=filename)
match_result = collections.namedtuple('MatchResult',
['metadata_list'])
match = match_result([None for _ in range(100)])
with mock.patch.object(FileSystems, 'match', return_value=[match]):
self.assertEqual(self._get_pipeline_mode(args),
PipelineModes.LARGE)
def test_failure_for_conflicting_flags_no_errors_with_file_input(self):
lines = [
'./gcp_variant_transforms/testing/data/vcf/valid-4.0.vcf\n',
'./gcp_variant_transforms/testing/data/vcf/valid-4.0.vcf\n',
'./gcp_variant_transforms/testing/data/vcf/valid-4.0.vcf\n'
]
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(lines=lines)
args = self._make_args([
'--input_file', filename, '--representative_header_file',
'gs://some_file'
])
self._options.validate(args)
def test_get_metadata_header_lines(self):
lines = [
'##fileformat=VCFv4.2\n',
'##INFO=<ID=NS,Number=1,Type=Integer,Description="Number samples">\n',
'##INFO=<ID=AF,Number=A,Type=Float,Description="Allele Frequency">\n',
'##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">\n',
'##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="GQ">\n',
'#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT Sample1 Sample2\n',
'19 1234567 mi1 G T 50 PASS NS=3 GT:GQ:DP 0/1:35:4 0/2:17:2',]
with temp_dir.TempDir() as tempdir:
file_path = self._create_temp_vcf_file(lines, tempdir)
header_lines = vcf_header_parser.get_metadata_header_lines(file_path)
self.assertEqual(header_lines, lines[:-2])
def test_one_file(self):
lines = [
'##fileformat=VCFv4.2\n',
'##INFO=<ID=NS,Number=1,Type=Integer,Description="Number samples">\n',
'##INFO=<ID=AF,Number=A,Type=Float,Description="Allele Frequency">\n',
'##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">\n',
'##FORMAT=<ID=GQ,Number=1,Type=Integer,Description="GQ">\n',
'#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT Sample1 Sample2\n']
with temp_dir.TempDir() as tempdir:
file_path = self._create_temp_vcf_file(lines, tempdir)
header_fields = vcf_header_parser.get_vcf_headers(file_path)
self.assertItemsEqual(['NS', 'AF'], header_fields.infos.keys())
self.assertItemsEqual(['GT', 'GQ'], header_fields.formats.keys())
def test_validation_failure_for_wrong_pattern_in_input_file(self):
lines = [
'./gcp_variant_transforms/testing/data/vcf/valid-4.0.vcf\n',
'non_existent.vcf\n',
'./gcp_variant_transforms/testing/data/vcf/valid-4.0.vcf\n'
]
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(lines=lines)
with self.assertRaisesRegex(
ValueError,
'Input pattern .* from .* did not match any files.'):
pipeline_common._get_all_patterns(input_pattern=None,
input_file=filename)
def test_pipeline_read_file_headers(self):
with temp_dir.TempDir() as tempdir:
filename = tempdir.create_temp_file(suffix='.vcf',
lines=self.lines)
pipeline = TestPipeline()
pcoll = pipeline | 'GetEstimates' >> GetEstimates(filename)
assert_that(
pcoll,
equal_to([_get_estimate_from_lines(self.lines, filename)]))
pipeline.run()
def test_invalid_file(self):
lines = [
'##fileformat=VCFv4.2\n',
'##INFO=<ID=NS,Number=1,Type=Integer,Description="Number samples">\n',
'##INFO=<ID=AF,Number=A,Type=Float,Desc\n',
'##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">\r\n',
'#CHROM POS ID REF ALT QUAL FILTER INFO FORMAT Sample1 Sample2\n']
with temp_dir.TempDir() as tempdir:
file_path = self._create_temp_vcf_file(lines, tempdir)
try:
vcf_header_parser.get_vcf_headers(file_path)
self.fail('Invalid VCF file must throw an exception.')
except ValueError:
pass
def test_preprocess_run_locally(self):
with temp_dir.TempDir() as tempdir:
report_path = filesystems.FileSystems.join(
tempdir.get_path(), PreprocessTest._REPORT_NAME)
resolved_headers_path = filesystems.FileSystems.join(
tempdir.get_path(), PreprocessTest._RESOLVED_HEADERS_FILE_NAME)
argv = [
'--input_pattern',
'gs://gcp-variant-transforms-testfiles/small_tests/infer-undefined'
'-header-fields.vcf', '--report_all_conflicts',
'--report_path', report_path, '--resolved_headers_path',
resolved_headers_path
]
vcf_to_bq_preprocess.run(argv)
assert filesystems.FileSystems.exists(report_path)
assert filesystems.FileSystems.exists(resolved_headers_path)
def test_read_file_pattern(self):
with temp_dir.TempDir() as tempdir:
headers_1 = [self.lines[1], self.lines[-1]]
headers_2 = [self.lines[2], self.lines[3], self.lines[-1]]
headers_3 = [self.lines[4], self.lines[-1]]
file_name_1 = tempdir.create_temp_file(suffix='.vcf', lines=headers_1)
file_name_2 = tempdir.create_temp_file(suffix='.vcf', lines=headers_2)
file_name_3 = tempdir.create_temp_file(suffix='.vcf', lines=headers_3)
actual = source_test_utils.read_from_source(VcfHeaderSource(
os.path.join(tempdir.get_path(), '*.vcf')))
expected = [_get_vcf_header_from_lines(h, file_name=file_name)
for h, file_name in [(headers_1, file_name_1),
(headers_2, file_name_2),
(headers_3, file_name_3)]]
asserts.header_vars_equal(expected)(actual)
def _generate_report_and_assert_contents_equal(
self,
expected_content, # type: List[str]
header_definitions, # type: merge_header_definitions.VcfHeaderDefinitions
resolved_headers=None, # type: VcfHeader
inferred_headers=None, # type: VcfHeader
malformed_records=None # type: List[vcfio.MalformedVcfRecord]
):
# type: (...) -> None
with temp_dir.TempDir() as tempdir:
file_path = FileSystems.join(tempdir.get_path(),
PreprocessReporterTest._REPORT_NAME)
preprocess_reporter.generate_report(header_definitions, file_path,
resolved_headers,
inferred_headers,
malformed_records)
with FileSystems.open(file_path) as f:
reader = f.readlines()
self.assertItemsEqual(reader, expected_content)
def test_config_failed_missing_region(self):
tempdir = temp_dir.TempDir()
missing_region = [
'- partition:',
' partition_name: "chr01_part1"',
' regions:',
' - "chr1:0-1,000,000"',
'- partition:',
' partition_name: "all_remaining"',
' regions:',
' - "residual"',
'- partition:',
' partition_name: "missing_region"',
' regions:',
]
with self.assertRaisesRegexp(
ValueError,
'Each partition must have at least one region.'):
_ = variant_partition.VariantPartition(
tempdir.create_temp_file(suffix='.yaml',
lines='\n'.join(missing_region)))
