import sys import parameters, genbank, trees, genomes, scores, families, islands if __name__ == "__main__": paramFN = sys.argv[1] paramD = parameters.loadParametersD(paramFN) ## load data structures we'll use below tree, strainStr2NumD, strainNum2StrD = trees.readTree(paramD['treeFN']) # an object for gene name conversions geneNames = genomes.geneNames(paramD['geneOrderFN'], strainStr2NumD, strainNum2StrD) subtreeL = trees.createSubtreeL(tree) subtreeL.sort() geneOrderT = genomes.createGeneOrderTs(paramD['geneOrderFN'], geneNames, subtreeL, strainStr2NumD) ## read scores scoresO = scores.readScores(paramD['scoresFN'], geneNames) ## make gene families familyIslandFormationSummaryF = open( paramD['familyIslandFormationSummaryFN'], 'w') familyL = families.families( tree, subtreeL, geneNames, scoresO, paramD['minNormThresh'], paramD['minCoreSynThresh'], paramD['minSynThresh'], paramD['synAdjustThresh'], paramD['synAdjustExtent'], paramD['familyFN'], strainNum2StrD, familyIslandFormationSummaryF)
paramFN=sys.argv[1] paramD = parameters.loadParametersD(paramFN) strainStr = sys.argv[2] validationFile = sys.argv[3] minGenes = int(sys.argv[4]) tree,strainStr2NumD,strainNum2StrD = trees.readTree(paramD['treeFN']) strainNum = strainStr2NumD[strainStr] #node = strainStr2NumD[strainStr] # load islands and genes islandByNodeL=islands.readIslands(paramD['islandOutFN'],tree,strainStr2NumD) geneNames = genomes.geneNames(paramD['geneOrderFN'],strainStr2NumD,strainNum2StrD) subtreeL=trees.createSubtreeL(tree) subtreeL.sort() geneOrderT=genomes.createGeneOrderTs(paramD['geneOrderFN'],geneNames,subtreeL,strainStr2NumD) familyL = families.readFamilies(paramD['familyFN'],tree,geneNames,strainStr2NumD) geneInfoD = genomes.readGeneInfoD(paramD['geneInfoFN']) totalBases, chromsL, allValRanges = readRanges(validationFile) nodesLL,uniqueStrains = nodesPerRange() islandsOfInterest()