def main():
config.print_config()
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
tempdir = tempfile.mkdtemp()
print('generating synthetic data to {} (this may take a while)'.format(tempdir))
for i in range(5):
im, seg = create_test_image_3d(128, 128, 128, num_seg_classes=1)
n = nib.Nifti1Image(im, np.eye(4))
nib.save(n, os.path.join(tempdir, 'im%i.nii.gz' % i))
n = nib.Nifti1Image(seg, np.eye(4))
nib.save(n, os.path.join(tempdir, 'seg%i.nii.gz' % i))
images = sorted(glob(os.path.join(tempdir, 'im*.nii.gz')))
segs = sorted(glob(os.path.join(tempdir, 'seg*.nii.gz')))
# define transforms for image and segmentation
imtrans = Compose([ScaleIntensity(), AddChannel(), ToTensor()])
segtrans = Compose([AddChannel(), ToTensor()])
val_ds = NiftiDataset(images, segs, transform=imtrans, seg_transform=segtrans, image_only=False)
# sliding window inference for one image at every iteration
val_loader = DataLoader(val_ds, batch_size=1, num_workers=1, pin_memory=torch.cuda.is_available())
device = torch.device('cuda:0')
model = UNet(
dimensions=3,
in_channels=1,
out_channels=1,
channels=(16, 32, 64, 128, 256),
strides=(2, 2, 2, 2),
num_res_units=2,
).to(device)
model.load_state_dict(torch.load('best_metric_model.pth'))
model.eval()
with torch.no_grad():
metric_sum = 0.
metric_count = 0
saver = NiftiSaver(output_dir='./output')
for val_data in val_loader:
val_images, val_labels = val_data[0].to(device), val_data[1].to(device)
# define sliding window size and batch size for windows inference
roi_size = (96, 96, 96)
sw_batch_size = 4
val_outputs = sliding_window_inference(val_images, roi_size, sw_batch_size, model)
value = compute_meandice(y_pred=val_outputs, y=val_labels, include_background=True,
to_onehot_y=False, add_sigmoid=True)
metric_count += len(value)
metric_sum += value.sum().item()
val_outputs = (val_outputs.sigmoid() >= 0.5).float()
saver.save_batch(val_outputs, val_data[2])
metric = metric_sum / metric_count
print('evaluation metric:', metric)
shutil.rmtree(tempdir)
def main(tempdir):
config.print_config()
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print(f"generating synthetic data to {tempdir} (this may take a while)")
for i in range(5):
im, seg = create_test_image_3d(128, 128, 128, num_seg_classes=1)
n = nib.Nifti1Image(im, np.eye(4))
nib.save(n, os.path.join(tempdir, f"im{i:d}.nii.gz"))
n = nib.Nifti1Image(seg, np.eye(4))
nib.save(n, os.path.join(tempdir, f"seg{i:d}.nii.gz"))
images = sorted(glob(os.path.join(tempdir, "im*.nii.gz")))
segs = sorted(glob(os.path.join(tempdir, "seg*.nii.gz")))
# define transforms for image and segmentation
imtrans = Compose([ScaleIntensity(), AddChannel(), ToTensor()])
segtrans = Compose([AddChannel(), ToTensor()])
val_ds = ImageDataset(images, segs, transform=imtrans, seg_transform=segtrans, image_only=False)
# sliding window inference for one image at every iteration
val_loader = DataLoader(val_ds, batch_size=1, num_workers=1, pin_memory=torch.cuda.is_available())
dice_metric = DiceMetric(include_background=True, reduction="mean")
post_trans = Compose([Activations(sigmoid=True), AsDiscrete(threshold_values=True)])
device = torch.device("cuda" if torch.cuda.is_available() else "cpu")
model = UNet(
dimensions=3,
in_channels=1,
out_channels=1,
channels=(16, 32, 64, 128, 256),
strides=(2, 2, 2, 2),
num_res_units=2,
).to(device)
model.load_state_dict(torch.load("best_metric_model_segmentation3d_array.pth"))
model.eval()
with torch.no_grad():
metric_sum = 0.0
metric_count = 0
saver = NiftiSaver(output_dir="./output")
for val_data in val_loader:
val_images, val_labels = val_data[0].to(device), val_data[1].to(device)
# define sliding window size and batch size for windows inference
roi_size = (96, 96, 96)
sw_batch_size = 4
val_outputs = sliding_window_inference(val_images, roi_size, sw_batch_size, model)
val_outputs = post_trans(val_outputs)
value, _ = dice_metric(y_pred=val_outputs, y=val_labels)
metric_count += len(value)
metric_sum += value.item() * len(value)
saver.save_batch(val_outputs, val_data[2])
metric = metric_sum / metric_count
print("evaluation metric:", metric)
def main(tempdir):
config.print_config()
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print(f"generating synthetic data to {tempdir} (this may take a while)")
for i in range(5):
im, seg = create_test_image_2d(128, 128, num_seg_classes=1)
Image.fromarray((im * 255).astype("uint8")).save(os.path.join(tempdir, f"img{i:d}.png"))
Image.fromarray((seg * 255).astype("uint8")).save(os.path.join(tempdir, f"seg{i:d}.png"))
images = sorted(glob(os.path.join(tempdir, "img*.png")))
segs = sorted(glob(os.path.join(tempdir, "seg*.png")))
# define transforms for image and segmentation
imtrans = Compose([LoadImage(image_only=True), AddChannel(), ScaleIntensity(), EnsureType()])
segtrans = Compose([LoadImage(image_only=True), AddChannel(), ScaleIntensity(), EnsureType()])
val_ds = ArrayDataset(images, imtrans, segs, segtrans)
# sliding window inference for one image at every iteration
val_loader = DataLoader(val_ds, batch_size=1, num_workers=1, pin_memory=torch.cuda.is_available())
dice_metric = DiceMetric(include_background=True, reduction="mean", get_not_nans=False)
post_trans = Compose([EnsureType(), Activations(sigmoid=True), AsDiscrete(threshold=0.5)])
saver = SaveImage(output_dir="./output", output_ext=".png", output_postfix="seg")
device = torch.device("cuda" if torch.cuda.is_available() else "cpu")
model = UNet(
spatial_dims=2,
in_channels=1,
out_channels=1,
channels=(16, 32, 64, 128, 256),
strides=(2, 2, 2, 2),
num_res_units=2,
).to(device)
model.load_state_dict(torch.load("best_metric_model_segmentation2d_array.pth"))
model.eval()
with torch.no_grad():
for val_data in val_loader:
val_images, val_labels = val_data[0].to(device), val_data[1].to(device)
# define sliding window size and batch size for windows inference
roi_size = (96, 96)
sw_batch_size = 4
val_outputs = sliding_window_inference(val_images, roi_size, sw_batch_size, model)
val_outputs = [post_trans(i) for i in decollate_batch(val_outputs)]
val_labels = decollate_batch(val_labels)
# compute metric for current iteration
dice_metric(y_pred=val_outputs, y=val_labels)
for val_output in val_outputs:
saver(val_output)
# aggregate the final mean dice result
print("evaluation metric:", dice_metric.aggregate().item())
# reset the status
dice_metric.reset()
import monai
from monai import config
from monai.data.nifti_reader import NiftiDataset
from monai.transforms import (AddChannel, Rescale, ToTensor,
UniformRandomPatch)
from monai.handlers.stats_handler import StatsHandler
from monai.handlers.mean_dice import MeanDice
from monai.visualize import img2tensorboard
from monai.data.synthetic import create_test_image_3d
from monai.handlers.utils import stopping_fn_from_metric
# assumes the framework is found here, change as necessary
sys.path.append("..")
config.print_config()
# Create a temporary directory and 50 random image, mask paris
tempdir = tempfile.mkdtemp()
for i in range(50):
im, seg = create_test_image_3d(256, 256, 256)
n = nib.Nifti1Image(im, np.eye(4))
nib.save(n, os.path.join(tempdir, 'im%i.nii.gz' % i))
n = nib.Nifti1Image(seg, np.eye(4))
nib.save(n, os.path.join(tempdir, 'seg%i.nii.gz' % i))
images = sorted(glob(os.path.join(tempdir, 'im*.nii.gz')))
segs = sorted(glob(os.path.join(tempdir, 'seg*.nii.gz')))
def run_training(train_file_list, valid_file_list, config_info):
"""
Pipeline to train a dynUNet segmentation model in MONAI. It is composed of the following main blocks:
* Data Preparation: Extract the filenames and prepare the training/validation processing transforms
* Load Data: Load training and validation data to PyTorch DataLoader
* Network Preparation: Define the network, loss function, optimiser and learning rate scheduler
* MONAI Evaluator: Initialise the dynUNet evaluator, i.e. the class providing utilities to perform validation
during training. Attach handlers to save the best model on the validation set. A 2D sliding window approach
on the 3D volume is used at evaluation. The mean 3D Dice is used as validation metric.
* MONAI Trainer: Initialise the dynUNet trainer, i.e. the class providing utilities to perform the training loop.
* Run training: The MONAI trainer is run, performing training and validation during training.
Args:
train_file_list: .txt or .csv file (with no header) storing two-columns filenames for training:
image filename in the first column and segmentation filename in the second column.
The two columns should be separated by a comma.
See monaifbs/config/mock_train_file_list_for_dynUnet_training.txt for an example of the expected format.
valid_file_list: .txt or .csv file (with no header) storing two-columns filenames for validation:
image filename in the first column and segmentation filename in the second column.
The two columns should be separated by a comma.
See monaifbs/config/mock_valid_file_list_for_dynUnet_training.txt for an example of the expected format.
config_info: dict, contains configuration parameters for sampling, network and training.
See monaifbs/config/monai_dynUnet_training_config.yml for an example of the expected fields.
"""
"""
Read input and configuration parameters
"""
# print MONAI config information
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print_config()
# print to log the parameter setups
print(yaml.dump(config_info))
# extract network parameters, perform checks/set defaults if not present and print them to log
if 'seg_labels' in config_info['training'].keys():
seg_labels = config_info['training']['seg_labels']
else:
seg_labels = [1]
nr_out_channels = len(seg_labels)
print("Considering the following {} labels in the segmentation: {}".format(nr_out_channels, seg_labels))
patch_size = config_info["training"]["inplane_size"] + [1]
print("Considering patch size = {}".format(patch_size))
spacing = config_info["training"]["spacing"]
print("Bringing all images to spacing = {}".format(spacing))
if 'model_to_load' in config_info['training'].keys() and config_info['training']['model_to_load'] is not None:
model_to_load = config_info['training']['model_to_load']
if not os.path.exists(model_to_load):
raise FileNotFoundError("Cannot find model: {}".format(model_to_load))
else:
print("Loading model from {}".format(model_to_load))
else:
model_to_load = None
# set up either GPU or CPU usage
if torch.cuda.is_available():
print("\n#### GPU INFORMATION ###")
print("Using device number: {}, name: {}\n".format(torch.cuda.current_device(), torch.cuda.get_device_name()))
current_device = torch.device("cuda:0")
else:
current_device = torch.device("cpu")
print("Using device: {}".format(current_device))
# set determinism if required
if 'manual_seed' in config_info['training'].keys() and config_info['training']['manual_seed'] is not None:
seed = config_info['training']['manual_seed']
else:
seed = None
if seed is not None:
print("Using determinism with seed = {}\n".format(seed))
set_determinism(seed=seed)
"""
Setup data output directory
"""
out_model_dir = os.path.join(config_info['output']['out_dir'],
datetime.now().strftime('%Y-%m-%d_%H-%M-%S') + '_' +
config_info['output']['out_postfix'])
print("Saving to directory {}\n".format(out_model_dir))
# create cache directory to store results for Persistent Dataset
if 'cache_dir' in config_info['output'].keys():
out_cache_dir = config_info['output']['cache_dir']
else:
out_cache_dir = os.path.join(out_model_dir, 'persistent_cache')
persistent_cache: Path = Path(out_cache_dir)
persistent_cache.mkdir(parents=True, exist_ok=True)
"""
Data preparation
"""
# Read the input files for training and validation
print("*** Loading input data for training...")
train_files = create_data_list_of_dictionaries(train_file_list)
print("Number of inputs for training = {}".format(len(train_files)))
val_files = create_data_list_of_dictionaries(valid_file_list)
print("Number of inputs for validation = {}".format(len(val_files)))
# Define MONAI processing transforms for the training data. This includes:
# - Load Nifti files and convert to format Batch x Channel x Dim1 x Dim2 x Dim3
# - CropForegroundd: Reduce the background from the MR image
# - InPlaneSpacingd: Perform in-plane resampling to the desired spacing, but preserve the resolution along the
# last direction (lowest resolution) to avoid introducing motion artefact resampling errors
# - SpatialPadd: Pad the in-plane size to the defined network input patch size [N, M] if needed
# - NormalizeIntensityd: Apply whitening
# - RandSpatialCropd: Crop a random patch from the input with size [B, C, N, M, 1]
# - SqueezeDimd: Convert the 3D patch to a 2D one as input to the network (i.e. bring it to size [B, C, N, M])
# - Apply data augmentation (RandZoomd, RandRotated, RandGaussianNoised, RandGaussianSmoothd, RandScaleIntensityd,
# RandFlipd)
# - ToTensor: convert to pytorch tensor
train_transforms = Compose(
[
LoadNiftid(keys=["image", "label"]),
AddChanneld(keys=["image", "label"]),
CropForegroundd(keys=["image", "label"], source_key="image"),
InPlaneSpacingd(
keys=["image", "label"],
pixdim=spacing,
mode=("bilinear", "nearest"),
),
SpatialPadd(keys=["image", "label"], spatial_size=patch_size,
mode=["constant", "edge"]),
NormalizeIntensityd(keys=["image"], nonzero=False, channel_wise=True),
RandSpatialCropd(keys=["image", "label"], roi_size=patch_size, random_size=False),
SqueezeDimd(keys=["image", "label"], dim=-1),
RandZoomd(
keys=["image", "label"],
min_zoom=0.9,
max_zoom=1.2,
mode=("bilinear", "nearest"),
align_corners=(True, None),
prob=0.16,
),
RandRotated(keys=["image", "label"], range_x=90, range_y=90, prob=0.2,
keep_size=True, mode=["bilinear", "nearest"],
padding_mode=["zeros", "border"]),
RandGaussianNoised(keys=["image"], std=0.01, prob=0.15),
RandGaussianSmoothd(
keys=["image"],
sigma_x=(0.5, 1.15),
sigma_y=(0.5, 1.15),
sigma_z=(0.5, 1.15),
prob=0.15,
),
RandScaleIntensityd(keys=["image"], factors=0.3, prob=0.15),
RandFlipd(["image", "label"], spatial_axis=[0, 1], prob=0.5),
ToTensord(keys=["image", "label"]),
]
)
# Define MONAI processing transforms for the validation data
# - Load Nifti files and convert to format Batch x Channel x Dim1 x Dim2 x Dim3
# - CropForegroundd: Reduce the background from the MR image
# - InPlaneSpacingd: Perform in-plane resampling to the desired spacing, but preserve the resolution along the
# last direction (lowest resolution) to avoid introducing motion artefact resampling errors
# - SpatialPadd: Pad the in-plane size to the defined network input patch size [N, M] if needed
# - NormalizeIntensityd: Apply whitening
# - ToTensor: convert to pytorch tensor
# NOTE: The validation data is kept 3D as a 2D sliding window approach is used throughout the volume at inference
val_transforms = Compose(
[
LoadNiftid(keys=["image", "label"]),
AddChanneld(keys=["image", "label"]),
CropForegroundd(keys=["image", "label"], source_key="image"),
InPlaneSpacingd(
keys=["image", "label"],
pixdim=spacing,
mode=("bilinear", "nearest"),
),
SpatialPadd(keys=["image", "label"], spatial_size=patch_size, mode=["constant", "edge"]),
NormalizeIntensityd(keys=["image"], nonzero=False, channel_wise=True),
ToTensord(keys=["image", "label"]),
]
)
"""
Load data
"""
# create training data loader
train_ds = PersistentDataset(data=train_files, transform=train_transforms,
cache_dir=persistent_cache)
train_loader = DataLoader(train_ds,
batch_size=config_info['training']['batch_size_train'],
shuffle=True,
num_workers=config_info['device']['num_workers'])
check_train_data = misc.first(train_loader)
print("Training data tensor shapes:")
print("Image = {}; Label = {}".format(check_train_data["image"].shape, check_train_data["label"].shape))
# create validation data loader
if config_info['training']['batch_size_valid'] != 1:
raise Exception("Batch size different from 1 at validation ar currently not supported")
val_ds = PersistentDataset(data=val_files, transform=val_transforms, cache_dir=persistent_cache)
val_loader = DataLoader(val_ds,
batch_size=1,
shuffle=False,
num_workers=config_info['device']['num_workers'])
check_valid_data = misc.first(val_loader)
print("Validation data tensor shapes (Example):")
print("Image = {}; Label = {}\n".format(check_valid_data["image"].shape, check_valid_data["label"].shape))
"""
Network preparation
"""
print("*** Preparing the network ...")
# automatically extracts the strides and kernels based on nnU-Net empirical rules
spacings = spacing[:2]
sizes = patch_size[:2]
strides, kernels = [], []
while True:
spacing_ratio = [sp / min(spacings) for sp in spacings]
stride = [2 if ratio <= 2 and size >= 8 else 1 for (ratio, size) in zip(spacing_ratio, sizes)]
kernel = [3 if ratio <= 2 else 1 for ratio in spacing_ratio]
if all(s == 1 for s in stride):
break
sizes = [i / j for i, j in zip(sizes, stride)]
spacings = [i * j for i, j in zip(spacings, stride)]
kernels.append(kernel)
strides.append(stride)
strides.insert(0, len(spacings) * [1])
kernels.append(len(spacings) * [3])
# initialise the network
net = DynUNet(
spatial_dims=2,
in_channels=1,
out_channels=nr_out_channels,
kernel_size=kernels,
strides=strides,
upsample_kernel_size=strides[1:],
norm_name="instance",
deep_supervision=True,
deep_supr_num=2,
res_block=False,
).to(current_device)
print(net)
# define the loss function
loss_function = choose_loss_function(nr_out_channels, config_info)
# define the optimiser and the learning rate scheduler
opt = torch.optim.SGD(net.parameters(), lr=float(config_info['training']['lr']), momentum=0.95)
scheduler = torch.optim.lr_scheduler.LambdaLR(
opt, lr_lambda=lambda epoch: (1 - epoch / config_info['training']['nr_train_epochs']) ** 0.9
)
"""
MONAI evaluator
"""
print("*** Preparing the dynUNet evaluator engine...\n")
# val_post_transforms = Compose(
# [
# Activationsd(keys="pred", sigmoid=True),
# ]
# )
val_handlers = [
StatsHandler(output_transform=lambda x: None),
TensorBoardStatsHandler(log_dir=os.path.join(out_model_dir, "valid"),
output_transform=lambda x: None,
global_epoch_transform=lambda x: trainer.state.iteration),
CheckpointSaver(save_dir=out_model_dir, save_dict={"net": net, "opt": opt}, save_key_metric=True,
file_prefix='best_valid'),
]
if config_info['output']['val_image_to_tensorboad']:
val_handlers.append(TensorBoardImageHandler(log_dir=os.path.join(out_model_dir, "valid"),
batch_transform=lambda x: (x["image"], x["label"]),
output_transform=lambda x: x["pred"], interval=2))
# Define customized evaluator
class DynUNetEvaluator(SupervisedEvaluator):
def _iteration(self, engine, batchdata):
inputs, targets = self.prepare_batch(batchdata)
inputs, targets = inputs.to(engine.state.device), targets.to(engine.state.device)
flip_inputs_1 = torch.flip(inputs, dims=(2,))
flip_inputs_2 = torch.flip(inputs, dims=(3,))
flip_inputs_3 = torch.flip(inputs, dims=(2, 3))
def _compute_pred():
pred = self.inferer(inputs, self.network)
# use random flipping as data augmentation at inference
flip_pred_1 = torch.flip(self.inferer(flip_inputs_1, self.network), dims=(2,))
flip_pred_2 = torch.flip(self.inferer(flip_inputs_2, self.network), dims=(3,))
flip_pred_3 = torch.flip(self.inferer(flip_inputs_3, self.network), dims=(2, 3))
return (pred + flip_pred_1 + flip_pred_2 + flip_pred_3) / 4
# execute forward computation
self.network.eval()
with torch.no_grad():
if self.amp:
with torch.cuda.amp.autocast():
predictions = _compute_pred()
else:
predictions = _compute_pred()
return {"image": inputs, "label": targets, "pred": predictions}
evaluator = DynUNetEvaluator(
device=current_device,
val_data_loader=val_loader,
network=net,
inferer=SlidingWindowInferer2D(roi_size=patch_size, sw_batch_size=4, overlap=0.0),
post_transform=None,
key_val_metric={
"Mean_dice": MeanDice(
include_background=False,
to_onehot_y=True,
mutually_exclusive=True,
output_transform=lambda x: (x["pred"], x["label"]),
)
},
val_handlers=val_handlers,
amp=False,
)
"""
MONAI trainer
"""
print("*** Preparing the dynUNet trainer engine...\n")
# train_post_transforms = Compose(
# [
# Activationsd(keys="pred", sigmoid=True),
# ]
# )
validation_every_n_epochs = config_info['training']['validation_every_n_epochs']
epoch_len = len(train_ds) // train_loader.batch_size
validation_every_n_iters = validation_every_n_epochs * epoch_len
# define event handlers for the trainer
writer_train = SummaryWriter(log_dir=os.path.join(out_model_dir, "train"))
train_handlers = [
LrScheduleHandler(lr_scheduler=scheduler, print_lr=True),
ValidationHandler(validator=evaluator, interval=validation_every_n_iters, epoch_level=False),
StatsHandler(tag_name="train_loss", output_transform=lambda x: x["loss"]),
TensorBoardStatsHandler(summary_writer=writer_train,
log_dir=os.path.join(out_model_dir, "train"), tag_name="Loss",
output_transform=lambda x: x["loss"],
global_epoch_transform=lambda x: trainer.state.iteration),
CheckpointSaver(save_dir=out_model_dir, save_dict={"net": net, "opt": opt},
save_final=True,
save_interval=2, epoch_level=True,
n_saved=config_info['output']['max_nr_models_saved']),
]
if model_to_load is not None:
train_handlers.append(CheckpointLoader(load_path=model_to_load, load_dict={"net": net, "opt": opt}))
# define customized trainer
class DynUNetTrainer(SupervisedTrainer):
def _iteration(self, engine, batchdata):
inputs, targets = self.prepare_batch(batchdata)
inputs, targets = inputs.to(engine.state.device), targets.to(engine.state.device)
def _compute_loss(preds, label):
labels = [label] + [interpolate(label, pred.shape[2:]) for pred in preds[1:]]
return sum([0.5 ** i * self.loss_function(p, l) for i, (p, l) in enumerate(zip(preds, labels))])
self.network.train()
self.optimizer.zero_grad()
if self.amp and self.scaler is not None:
with torch.cuda.amp.autocast():
predictions = self.inferer(inputs, self.network)
loss = _compute_loss(predictions, targets)
self.scaler.scale(loss).backward()
self.scaler.step(self.optimizer)
self.scaler.update()
else:
predictions = self.inferer(inputs, self.network)
loss = _compute_loss(predictions, targets).mean()
loss.backward()
self.optimizer.step()
return {"image": inputs, "label": targets, "pred": predictions, "loss": loss.item()}
trainer = DynUNetTrainer(
device=current_device,
max_epochs=config_info['training']['nr_train_epochs'],
train_data_loader=train_loader,
network=net,
optimizer=opt,
loss_function=loss_function,
inferer=SimpleInferer(),
post_transform=None,
key_train_metric=None,
train_handlers=train_handlers,
amp=False,
)
"""
Run training
"""
print("*** Run training...")
trainer.run()
print("Done!")
def main(tempdir):
config.print_config()
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print(f"generating synthetic data to {tempdir} (this may take a while)")
for i in range(5):
im, seg = create_test_image_3d(128, 128, 128, num_seg_classes=1)
n = nib.Nifti1Image(im, np.eye(4))
nib.save(n, os.path.join(tempdir, f"im{i:d}.nii.gz"))
n = nib.Nifti1Image(seg, np.eye(4))
nib.save(n, os.path.join(tempdir, f"seg{i:d}.nii.gz"))
images = sorted(glob(os.path.join(tempdir, "im*.nii.gz")))
segs = sorted(glob(os.path.join(tempdir, "seg*.nii.gz")))
# define transforms for image and segmentation
imtrans = Compose([ScaleIntensity(), AddChannel(), ToTensor()])
segtrans = Compose([AddChannel(), ToTensor()])
ds = ImageDataset(images,
segs,
transform=imtrans,
seg_transform=segtrans,
image_only=False)
device = torch.device("cuda" if torch.cuda.is_available() else "cpu")
net = UNet(
dimensions=3,
in_channels=1,
out_channels=1,
channels=(16, 32, 64, 128, 256),
strides=(2, 2, 2, 2),
num_res_units=2,
).to(device)
# define sliding window size and batch size for windows inference
roi_size = (96, 96, 96)
sw_batch_size = 4
post_trans = Compose(
[Activations(sigmoid=True),
AsDiscrete(threshold_values=True)])
def _sliding_window_processor(engine, batch):
net.eval()
with torch.no_grad():
val_images, val_labels = batch[0].to(device), batch[1].to(device)
seg_probs = sliding_window_inference(val_images, roi_size,
sw_batch_size, net)
seg_probs = post_trans(seg_probs)
return seg_probs, val_labels
evaluator = Engine(_sliding_window_processor)
# add evaluation metric to the evaluator engine
MeanDice().attach(evaluator, "Mean_Dice")
# StatsHandler prints loss at every iteration and print metrics at every epoch,
# we don't need to print loss for evaluator, so just print metrics, user can also customize print functions
val_stats_handler = StatsHandler(
name="evaluator",
output_transform=lambda x:
None, # no need to print loss value, so disable per iteration output
)
val_stats_handler.attach(evaluator)
# for the array data format, assume the 3rd item of batch data is the meta_data
file_saver = SegmentationSaver(
output_dir="tempdir",
output_ext=".nii.gz",
output_postfix="seg",
name="evaluator",
batch_transform=lambda x: x[2],
output_transform=lambda output: output[0],
)
file_saver.attach(evaluator)
# the model was trained by "unet_training_array" example
ckpt_saver = CheckpointLoader(
load_path="./runs_array/net_checkpoint_100.pt", load_dict={"net": net})
ckpt_saver.attach(evaluator)
# sliding window inference for one image at every iteration
loader = DataLoader(ds,
batch_size=1,
num_workers=1,
pin_memory=torch.cuda.is_available())
state = evaluator.run(loader)
print(state)
AddChanneld,
Compose,
CropForegroundd,
LoadImaged,
KeepLargestConnectedComponent,
LabelToContour,
Orientationd,
RandCropByPosNegLabeld,
ScaleIntensityRanged,
Spacingd,
ToTensord,
)
from monai.utils import first, set_determinism
from numpy import math
print_config()
print("KIDNEYS")
"""## Setup data directory
You can specify a directory with the `MONAI_DATA_DIRECTORY` environment variable.
This allows you to save results and reuse downloads.
If not specified a temporary directory will be used.
"""
"""## Download dataset
Downloads and extracts the dataset.
The dataset comes from http://medicaldecathlon.com/.
"""
md5 = "410d4a301da4e5b2f6f86ec3ddba524e"
def main():
config.print_config()
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
tempdir = tempfile.mkdtemp()
print('generating synthetic data to {} (this may take a while)'.format(tempdir))
for i in range(5):
im, seg = create_test_image_3d(128, 128, 128, num_seg_classes=1)
n = nib.Nifti1Image(im, np.eye(4))
nib.save(n, os.path.join(tempdir, 'im%i.nii.gz' % i))
n = nib.Nifti1Image(seg, np.eye(4))
nib.save(n, os.path.join(tempdir, 'seg%i.nii.gz' % i))
images = sorted(glob(os.path.join(tempdir, 'im*.nii.gz')))
segs = sorted(glob(os.path.join(tempdir, 'seg*.nii.gz')))
# define transforms for image and segmentation
imtrans = Compose([ScaleIntensity(), AddChannel(), ToTensor()])
segtrans = Compose([AddChannel(), ToTensor()])
ds = NiftiDataset(images, segs, transform=imtrans, seg_transform=segtrans, image_only=False)
device = torch.device('cuda:0')
net = UNet(
dimensions=3,
in_channels=1,
out_channels=1,
channels=(16, 32, 64, 128, 256),
strides=(2, 2, 2, 2),
num_res_units=2,
)
net.to(device)
# define sliding window size and batch size for windows inference
roi_size = (96, 96, 96)
sw_batch_size = 4
def _sliding_window_processor(engine, batch):
net.eval()
with torch.no_grad():
val_images, val_labels = batch[0].to(device), batch[1].to(device)
seg_probs = sliding_window_inference(val_images, roi_size, sw_batch_size, net)
return seg_probs, val_labels
evaluator = Engine(_sliding_window_processor)
# add evaluation metric to the evaluator engine
MeanDice(add_sigmoid=True, to_onehot_y=False).attach(evaluator, 'Mean_Dice')
# StatsHandler prints loss at every iteration and print metrics at every epoch,
# we don't need to print loss for evaluator, so just print metrics, user can also customize print functions
val_stats_handler = StatsHandler(
name='evaluator',
output_transform=lambda x: None # no need to print loss value, so disable per iteration output
)
val_stats_handler.attach(evaluator)
# for the array data format, assume the 3rd item of batch data is the meta_data
file_saver = SegmentationSaver(
output_dir='tempdir', output_ext='.nii.gz', output_postfix='seg', name='evaluator',
batch_transform=lambda x: x[2], output_transform=lambda output: predict_segmentation(output[0]))
file_saver.attach(evaluator)
# the model was trained by "unet_training_array" example
ckpt_saver = CheckpointLoader(load_path='./runs/net_checkpoint_50.pth', load_dict={'net': net})
ckpt_saver.attach(evaluator)
# sliding window inference for one image at every iteration
loader = DataLoader(ds, batch_size=1, num_workers=1, pin_memory=torch.cuda.is_available())
state = evaluator.run(loader)
shutil.rmtree(tempdir)
def main():
print_config()
# Define paths for running the script
data_dir = os.path.normpath('/to/be/defined')
json_path = os.path.normpath('/to/be/defined')
logdir = os.path.normpath('/to/be/defined')
# If use_pretrained is set to 0, ViT weights will not be loaded and random initialization is used
use_pretrained = 1
pretrained_path = os.path.normpath('/to/be/defined')
# Training Hyper-parameters
lr = 1e-4
max_iterations = 30000
eval_num = 100
if os.path.exists(logdir) == False:
os.mkdir(logdir)
# Training & Validation Transform chain
train_transforms = Compose([
LoadImaged(keys=["image", "label"]),
AddChanneld(keys=["image", "label"]),
Spacingd(
keys=["image", "label"],
pixdim=(1.5, 1.5, 2.0),
mode=("bilinear", "nearest"),
),
Orientationd(keys=["image", "label"], axcodes="RAS"),
ScaleIntensityRanged(
keys=["image"],
a_min=-175,
a_max=250,
b_min=0.0,
b_max=1.0,
clip=True,
),
CropForegroundd(keys=["image", "label"], source_key="image"),
RandCropByPosNegLabeld(
keys=["image", "label"],
label_key="label",
spatial_size=(96, 96, 96),
pos=1,
neg=1,
num_samples=4,
image_key="image",
image_threshold=0,
),
RandFlipd(
keys=["image", "label"],
spatial_axis=[0],
prob=0.10,
),
RandFlipd(
keys=["image", "label"],
spatial_axis=[1],
prob=0.10,
),
RandFlipd(
keys=["image", "label"],
spatial_axis=[2],
prob=0.10,
),
RandRotate90d(
keys=["image", "label"],
prob=0.10,
max_k=3,
),
RandShiftIntensityd(
keys=["image"],
offsets=0.10,
prob=0.50,
),
ToTensord(keys=["image", "label"]),
])
val_transforms = Compose([
LoadImaged(keys=["image", "label"]),
AddChanneld(keys=["image", "label"]),
Spacingd(
keys=["image", "label"],
pixdim=(1.5, 1.5, 2.0),
mode=("bilinear", "nearest"),
),
Orientationd(keys=["image", "label"], axcodes="RAS"),
ScaleIntensityRanged(keys=["image"],
a_min=-175,
a_max=250,
b_min=0.0,
b_max=1.0,
clip=True),
CropForegroundd(keys=["image", "label"], source_key="image"),
ToTensord(keys=["image", "label"]),
])
datalist = load_decathlon_datalist(base_dir=data_dir,
data_list_file_path=json_path,
is_segmentation=True,
data_list_key="training")
val_files = load_decathlon_datalist(base_dir=data_dir,
data_list_file_path=json_path,
is_segmentation=True,
data_list_key="validation")
train_ds = CacheDataset(
data=datalist,
transform=train_transforms,
cache_num=24,
cache_rate=1.0,
num_workers=4,
)
train_loader = DataLoader(train_ds,
batch_size=1,
shuffle=True,
num_workers=4,
pin_memory=True)
val_ds = CacheDataset(data=val_files,
transform=val_transforms,
cache_num=6,
cache_rate=1.0,
num_workers=4)
val_loader = DataLoader(val_ds,
batch_size=1,
shuffle=False,
num_workers=4,
pin_memory=True)
case_num = 0
img = val_ds[case_num]["image"]
label = val_ds[case_num]["label"]
img_shape = img.shape
label_shape = label.shape
print(f"image shape: {img_shape}, label shape: {label_shape}")
os.environ["CUDA_DEVICE_ORDER"] = "PCI_BUS_ID"
device = torch.device("cuda" if torch.cuda.is_available() else "cpu")
model = UNETR(
in_channels=1,
out_channels=14,
img_size=(96, 96, 96),
feature_size=16,
hidden_size=768,
mlp_dim=3072,
num_heads=12,
pos_embed="conv",
norm_name="instance",
res_block=True,
dropout_rate=0.0,
)
# Load ViT backbone weights into UNETR
if use_pretrained == 1:
print('Loading Weights from the Path {}'.format(pretrained_path))
vit_dict = torch.load(pretrained_path)
vit_weights = vit_dict['state_dict']
# Delete the following variable names conv3d_transpose.weight, conv3d_transpose.bias,
# conv3d_transpose_1.weight, conv3d_transpose_1.bias as they were used to match dimensions
# while pretraining with ViTAutoEnc and are not a part of ViT backbone (this is used in UNETR)
vit_weights.pop('conv3d_transpose_1.bias')
vit_weights.pop('conv3d_transpose_1.weight')
vit_weights.pop('conv3d_transpose.bias')
vit_weights.pop('conv3d_transpose.weight')
model.vit.load_state_dict(vit_weights)
print('Pretrained Weights Succesfully Loaded !')
elif use_pretrained == 0:
print(
'No weights were loaded, all weights being used are randomly initialized!'
)
model.to(device)
loss_function = DiceCELoss(to_onehot_y=True, softmax=True)
torch.backends.cudnn.benchmark = True
optimizer = torch.optim.AdamW(model.parameters(), lr=lr, weight_decay=1e-5)
post_label = AsDiscrete(to_onehot=14)
post_pred = AsDiscrete(argmax=True, to_onehot=14)
dice_metric = DiceMetric(include_background=True,
reduction="mean",
get_not_nans=False)
global_step = 0
dice_val_best = 0.0
global_step_best = 0
epoch_loss_values = []
metric_values = []
def validation(epoch_iterator_val):
model.eval()
dice_vals = list()
with torch.no_grad():
for step, batch in enumerate(epoch_iterator_val):
val_inputs, val_labels = (batch["image"].cuda(),
batch["label"].cuda())
val_outputs = sliding_window_inference(val_inputs,
(96, 96, 96), 4, model)
val_labels_list = decollate_batch(val_labels)
val_labels_convert = [
post_label(val_label_tensor)
for val_label_tensor in val_labels_list
]
val_outputs_list = decollate_batch(val_outputs)
val_output_convert = [
post_pred(val_pred_tensor)
for val_pred_tensor in val_outputs_list
]
dice_metric(y_pred=val_output_convert, y=val_labels_convert)
dice = dice_metric.aggregate().item()
dice_vals.append(dice)
epoch_iterator_val.set_description(
"Validate (%d / %d Steps) (dice=%2.5f)" %
(global_step, 10.0, dice))
dice_metric.reset()
mean_dice_val = np.mean(dice_vals)
return mean_dice_val
def train(global_step, train_loader, dice_val_best, global_step_best):
model.train()
epoch_loss = 0
step = 0
epoch_iterator = tqdm(train_loader,
desc="Training (X / X Steps) (loss=X.X)",
dynamic_ncols=True)
for step, batch in enumerate(epoch_iterator):
step += 1
x, y = (batch["image"].cuda(), batch["label"].cuda())
logit_map = model(x)
loss = loss_function(logit_map, y)
loss.backward()
epoch_loss += loss.item()
optimizer.step()
optimizer.zero_grad()
epoch_iterator.set_description(
"Training (%d / %d Steps) (loss=%2.5f)" %
(global_step, max_iterations, loss))
if (global_step % eval_num == 0
and global_step != 0) or global_step == max_iterations:
epoch_iterator_val = tqdm(
val_loader,
desc="Validate (X / X Steps) (dice=X.X)",
dynamic_ncols=True)
dice_val = validation(epoch_iterator_val)
epoch_loss /= step
epoch_loss_values.append(epoch_loss)
metric_values.append(dice_val)
if dice_val > dice_val_best:
dice_val_best = dice_val
global_step_best = global_step
torch.save(model.state_dict(),
os.path.join(logdir, "best_metric_model.pth"))
print(
"Model Was Saved ! Current Best Avg. Dice: {} Current Avg. Dice: {}"
.format(dice_val_best, dice_val))
else:
print(
"Model Was Not Saved ! Current Best Avg. Dice: {} Current Avg. Dice: {}"
.format(dice_val_best, dice_val))
plt.figure(1, (12, 6))
plt.subplot(1, 2, 1)
plt.title("Iteration Average Loss")
x = [eval_num * (i + 1) for i in range(len(epoch_loss_values))]
y = epoch_loss_values
plt.xlabel("Iteration")
plt.plot(x, y)
plt.grid()
plt.subplot(1, 2, 2)
plt.title("Val Mean Dice")
x = [eval_num * (i + 1) for i in range(len(metric_values))]
y = metric_values
plt.xlabel("Iteration")
plt.plot(x, y)
plt.grid()
plt.savefig(
os.path.join(logdir, 'btcv_finetune_quick_update.png'))
plt.clf()
plt.close(1)
global_step += 1
return global_step, dice_val_best, global_step_best
while global_step < max_iterations:
global_step, dice_val_best, global_step_best = train(
global_step, train_loader, dice_val_best, global_step_best)
model.load_state_dict(
torch.load(os.path.join(logdir, "best_metric_model.pth")))
print(f"train completed, best_metric: {dice_val_best:.4f} "
f"at iteration: {global_step_best}")
def main(train_output):
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print_config()
# Setup directories
dirs = setup_directories()
# Setup torch device
device, using_gpu = create_device("cuda")
# Load and randomize images
# HACKATON image and segmentation data
hackathon_dir = os.path.join(dirs["data"], 'HACKATHON')
map_fn = lambda x: (x[0], int(x[1]))
with open(os.path.join(hackathon_dir, "train.txt"), 'r') as fp:
train_info_hackathon = [
map_fn(entry.strip().split(',')) for entry in fp.readlines()
]
image_dir = os.path.join(hackathon_dir, 'images', 'train')
seg_dir = os.path.join(hackathon_dir, 'segmentations', 'train')
_train_data_hackathon = get_data_from_info(image_dir,
seg_dir,
train_info_hackathon,
dual_output=False)
large_image_splitter(_train_data_hackathon, dirs["cache"])
balance_training_data(_train_data_hackathon, seed=72)
# PSUF data
"""psuf_dir = os.path.join(dirs["data"], 'psuf')
with open(os.path.join(psuf_dir, "train.txt"), 'r') as fp:
train_info = [entry.strip().split(',') for entry in fp.readlines()]
image_dir = os.path.join(psuf_dir, 'images')
train_data_psuf = get_data_from_info(image_dir, None, train_info)"""
# Split data into train, validate and test
train_split, test_data_hackathon = train_test_split(_train_data_hackathon,
test_size=0.2,
shuffle=True,
random_state=42)
#train_data_hackathon, valid_data_hackathon = train_test_split(train_split, test_size=0.2, shuffle=True, random_state=43)
# Setup transforms
# Crop foreground
crop_foreground = CropForegroundd(
keys=["image"],
source_key="image",
margin=(5, 5, 0),
#select_fn = lambda x: x != 0
)
# Crop Z
crop_z = RelativeCropZd(keys=["image"], relative_z_roi=(0.07, 0.12))
# Window width and level (window center)
WW, WL = 1500, -600
ct_window = CTWindowd(keys=["image"], width=WW, level=WL)
spatial_pad = SpatialPadd(keys=["image"], spatial_size=(-1, -1, 30))
resize = Resized(keys=["image"],
spatial_size=(int(512 * 0.50), int(512 * 0.50), -1),
mode="trilinear")
# Create transforms
common_transform = Compose([
LoadImaged(keys=["image"]),
ct_window,
CTSegmentation(keys=["image"]),
AddChanneld(keys=["image"]),
resize,
crop_foreground,
crop_z,
spatial_pad,
])
hackathon_train_transfrom = Compose([
common_transform,
ToTensord(keys=["image"]),
]).flatten()
psuf_transforms = Compose([
LoadImaged(keys=["image"]),
AddChanneld(keys=["image"]),
ToTensord(keys=["image"]),
])
# Setup data
#set_determinism(seed=100)
test_dataset = PersistentDataset(data=test_data_hackathon[:],
transform=hackathon_train_transfrom,
cache_dir=dirs["persistent"])
test_loader = DataLoader(test_dataset,
batch_size=2,
shuffle=True,
pin_memory=using_gpu,
num_workers=1,
collate_fn=PadListDataCollate(
Method.SYMMETRIC, NumpyPadMode.CONSTANT))
# Setup network, loss function, optimizer and scheduler
network = nets.DenseNet121(spatial_dims=3, in_channels=1,
out_channels=1).to(device)
# Setup validator and trainer
valid_post_transforms = Compose([
Activationsd(keys="pred", sigmoid=True),
])
# Setup tester
tester = Tester(device=device,
test_data_loader=test_loader,
load_dir=train_output,
out_dir=dirs["out"],
network=network,
post_transform=valid_post_transforms,
non_blocking=using_gpu,
amp=using_gpu)
# Run tester
tester.run()
def run_inference(input_data, config_info):
"""
Pipeline to run inference with MONAI dynUNet model. The pipeline reads the input filenames, applies the required
preprocessing and creates the pytorch dataloader; it then performs evaluation on each input file using a trained
dynUNet model (random flipping augmentation is applied at inference).
It uses the dynUNet model implemented in the MONAI framework
(https://github.com/Project-MONAI/MONAI/blob/master/monai/networks/nets/dynunet.py)
which is inspired by the nnU-Net framework (https://arxiv.org/abs/1809.10486)
Inference is performed in 2D slice-by-slice, all slices are then recombined together into the 3D volume.
Args:
input_data: str or list of strings, filenames of images to be processed
config_info: dict, contains the configuration parameters to reload the trained model
"""
"""
Read input and configuration parameters
"""
val_files = create_data_list_of_dictionaries(input_data)
# print MONAI config information
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print("*** MONAI config: ")
print_config()
# print to log the parameter setups
print("*** Network inference config: ")
print(yaml.dump(config_info))
# inference params
nr_out_channels = config_info['inference']['nr_out_channels']
spacing = config_info["inference"]["spacing"]
prob_thr = config_info['inference']['probability_threshold']
model_to_load = config_info['inference']['model_to_load']
if not os.path.exists(model_to_load):
raise FileNotFoundError('Trained model not found')
patch_size = config_info["inference"]["inplane_size"] + [1]
print("Considering patch size = {}".format(patch_size))
# set up either GPU or CPU usage
if torch.cuda.is_available():
print("\n#### GPU INFORMATION ###")
print("Using device number: {}, name: {}".format(
torch.cuda.current_device(), torch.cuda.get_device_name()))
current_device = torch.device("cuda:0")
else:
current_device = torch.device("cpu")
print("Using device: {}".format(current_device))
"""
Data Preparation
"""
print("*** Preparing data ... ")
# data preprocessing for inference:
# - convert data to right format [batch, channel, dim, dim, dim]
# - resample to the training resolution in-plane (not along z)
# - apply whitening
# - convert to tensor
val_transforms = Compose([
LoadNiftid(keys=["image"]),
AddChanneld(keys=["image"]),
InPlaneSpacingd(
keys=["image"],
pixdim=spacing,
mode="bilinear",
),
NormalizeIntensityd(keys=["image"], nonzero=False, channel_wise=True),
ToTensord(keys=["image"]),
])
# create a validation data loader
val_ds = Dataset(data=val_files, transform=val_transforms)
val_loader = DataLoader(val_ds,
batch_size=1,
num_workers=config_info['device']['num_workers'])
def prepare_batch(batchdata):
assert isinstance(batchdata,
dict), "prepare_batch expects dictionary input data."
return ((batchdata["image"],
batchdata["label"]) if "label" in batchdata else
(batchdata["image"], None))
"""
Network preparation
"""
print("*** Preparing network ... ")
# automatically extracts the strides and kernels based on nnU-Net empirical rules
spacings = spacing[:2]
sizes = patch_size[:2]
strides, kernels = [], []
while True:
spacing_ratio = [sp / min(spacings) for sp in spacings]
stride = [
2 if ratio <= 2 and size >= 8 else 1
for (ratio, size) in zip(spacing_ratio, sizes)
]
kernel = [3 if ratio <= 2 else 1 for ratio in spacing_ratio]
if all(s == 1 for s in stride):
break
sizes = [i / j for i, j in zip(sizes, stride)]
spacings = [i * j for i, j in zip(spacings, stride)]
kernels.append(kernel)
strides.append(stride)
strides.insert(0, len(spacings) * [1])
kernels.append(len(spacings) * [3])
net = DynUNet(spatial_dims=2,
in_channels=1,
out_channels=nr_out_channels,
kernel_size=kernels,
strides=strides,
upsample_kernel_size=strides[1:],
norm_name="instance",
deep_supervision=True,
deep_supr_num=2,
res_block=False).to(current_device)
"""
Set ignite evaluator to perform inference
"""
print("*** Preparing evaluator ... ")
if nr_out_channels == 1:
do_sigmoid = True
do_softmax = False
elif nr_out_channels > 1:
do_sigmoid = False
do_softmax = True
else:
raise Exception("incompatible number of output channels")
print("Using sigmoid={} and softmax={} as final activation".format(
do_sigmoid, do_softmax))
val_post_transforms = Compose([
Activationsd(keys="pred", sigmoid=do_sigmoid, softmax=do_softmax),
AsDiscreted(keys="pred",
argmax=True,
threshold_values=True,
logit_thresh=prob_thr),
KeepLargestConnectedComponentd(keys="pred", applied_labels=1)
])
val_handlers = [
StatsHandler(output_transform=lambda x: None),
CheckpointLoader(load_path=model_to_load,
load_dict={"net": net},
map_location=torch.device('cpu')),
SegmentationSaver(
output_dir=config_info['output']['out_dir'],
output_ext='.nii.gz',
output_postfix=config_info['output']['out_postfix'],
batch_transform=lambda batch: batch["image_meta_dict"],
output_transform=lambda output: output["pred"],
),
]
# Define customized evaluator
class DynUNetEvaluator(SupervisedEvaluator):
def _iteration(self, engine, batchdata):
inputs, targets = self.prepare_batch(batchdata)
inputs = inputs.to(engine.state.device)
if targets is not None:
targets = targets.to(engine.state.device)
flip_inputs_1 = torch.flip(inputs, dims=(2, ))
flip_inputs_2 = torch.flip(inputs, dims=(3, ))
flip_inputs_3 = torch.flip(inputs, dims=(2, 3))
def _compute_pred():
pred = self.inferer(inputs, self.network)
# use random flipping as data augmentation at inference
flip_pred_1 = torch.flip(self.inferer(flip_inputs_1,
self.network),
dims=(2, ))
flip_pred_2 = torch.flip(self.inferer(flip_inputs_2,
self.network),
dims=(3, ))
flip_pred_3 = torch.flip(self.inferer(flip_inputs_3,
self.network),
dims=(2, 3))
return (pred + flip_pred_1 + flip_pred_2 + flip_pred_3) / 4
# execute forward computation
self.network.eval()
with torch.no_grad():
if self.amp:
with torch.cuda.amp.autocast():
predictions = _compute_pred()
else:
predictions = _compute_pred()
return {"image": inputs, "label": targets, "pred": predictions}
evaluator = DynUNetEvaluator(
device=current_device,
val_data_loader=val_loader,
network=net,
prepare_batch=prepare_batch,
inferer=SlidingWindowInferer2D(roi_size=patch_size,
sw_batch_size=4,
overlap=0.0),
post_transform=val_post_transforms,
val_handlers=val_handlers,
amp=False,
)
"""
Run inference
"""
print("*** Running evaluator ... ")
evaluator.run()
print("Done!")
return
def main(tempdir):
print_config()
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print(f"generating synthetic data to {tempdir} (this may take a while)")
for i in range(5):
im, _ = create_test_image_3d(128,
128,
128,
num_seg_classes=1,
channel_dim=-1)
n = nib.Nifti1Image(im, np.eye(4))
nib.save(n, os.path.join(tempdir, f"im{i:d}.nii.gz"))
images = sorted(glob(os.path.join(tempdir, "im*.nii.gz")))
files = [{"img": img} for img in images]
# define pre transforms
pre_transforms = Compose([
LoadImaged(keys="img"),
EnsureChannelFirstd(keys="img"),
Orientationd(keys="img", axcodes="RAS"),
Resized(keys="img",
spatial_size=(96, 96, 96),
mode="trilinear",
align_corners=True),
ScaleIntensityd(keys="img"),
EnsureTyped(keys="img"),
])
# define dataset and dataloader
dataset = Dataset(data=files, transform=pre_transforms)
dataloader = DataLoader(dataset, batch_size=2, num_workers=4)
# define post transforms
post_transforms = Compose([
EnsureTyped(keys="pred"),
Activationsd(keys="pred", sigmoid=True),
Invertd(
keys=
"pred", # invert the `pred` data field, also support multiple fields
transform=pre_transforms,
orig_keys=
"img", # get the previously applied pre_transforms information on the `img` data field,
# then invert `pred` based on this information. we can use same info
# for multiple fields, also support different orig_keys for different fields
meta_keys=
"pred_meta_dict", # key field to save inverted meta data, every item maps to `keys`
orig_meta_keys=
"img_meta_dict", # get the meta data from `img_meta_dict` field when inverting,
# for example, may need the `affine` to invert `Spacingd` transform,
# multiple fields can use the same meta data to invert
meta_key_postfix=
"meta_dict", # if `meta_keys=None`, use "{keys}_{meta_key_postfix}" as the meta key,
# if `orig_meta_keys=None`, use "{orig_keys}_{meta_key_postfix}",
# otherwise, no need this arg during inverting
nearest_interp=
False, # don't change the interpolation mode to "nearest" when inverting transforms
# to ensure a smooth output, then execute `AsDiscreted` transform
to_tensor=True, # convert to PyTorch Tensor after inverting
),
AsDiscreted(keys="pred", threshold=0.5),
SaveImaged(keys="pred",
meta_keys="pred_meta_dict",
output_dir="./out",
output_postfix="seg",
resample=False),
])
device = torch.device("cuda" if torch.cuda.is_available() else "cpu")
net = UNet(
spatial_dims=3,
in_channels=1,
out_channels=1,
channels=(16, 32, 64, 128, 256),
strides=(2, 2, 2, 2),
num_res_units=2,
).to(device)
net.load_state_dict(
torch.load("best_metric_model_segmentation3d_dict.pth"))
net.eval()
with torch.no_grad():
for d in dataloader:
images = d["img"].to(device)
# define sliding window size and batch size for windows inference
d["pred"] = sliding_window_inference(inputs=images,
roi_size=(96, 96, 96),
sw_batch_size=4,
predictor=net)
# decollate the batch data into a list of dictionaries, then execute postprocessing transforms
d = [post_transforms(i) for i in decollate_batch(d)]
def main(tempdir):
print_config()
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print(f"generating synthetic data to {tempdir} (this may take a while)")
for i in range(5):
im, _ = create_test_image_3d(128,
128,
128,
num_seg_classes=1,
channel_dim=-1)
n = nib.Nifti1Image(im, np.eye(4))
nib.save(n, os.path.join(tempdir, f"im{i:d}.nii.gz"))
images = sorted(glob(os.path.join(tempdir, "im*.nii.gz")))
files = [{"img": img} for img in images]
# define pre transforms
pre_transforms = Compose([
LoadImaged(keys="img"),
EnsureChannelFirstd(keys="img"),
Orientationd(keys="img", axcodes="RAS"),
Resized(keys="img",
spatial_size=(96, 96, 96),
mode="trilinear",
align_corners=True),
ScaleIntensityd(keys="img"),
ToTensord(keys="img"),
])
# define dataset and dataloader
dataset = Dataset(data=files, transform=pre_transforms)
dataloader = DataLoader(dataset, batch_size=2, num_workers=4)
# define post transforms
post_transforms = Compose([
Activationsd(keys="pred", sigmoid=True),
AsDiscreted(keys="pred", threshold_values=True),
Invertd(keys="pred",
transform=pre_transforms,
loader=dataloader,
orig_keys="img",
nearest_interp=True),
SaveImaged(keys="pred_inverted",
output_dir="./output",
output_postfix="seg",
resample=False),
])
device = torch.device("cuda" if torch.cuda.is_available() else "cpu")
net = UNet(
dimensions=3,
in_channels=1,
out_channels=1,
channels=(16, 32, 64, 128, 256),
strides=(2, 2, 2, 2),
num_res_units=2,
).to(device)
net.load_state_dict(
torch.load("best_metric_model_segmentation3d_dict.pth"))
net.eval()
with torch.no_grad():
for d in dataloader:
images = d["img"].to(device)
# define sliding window size and batch size for windows inference
d["pred"] = sliding_window_inference(inputs=images,
roi_size=(96, 96, 96),
sw_batch_size=4,
predictor=net)
# execute post transforms to invert spatial transforms and save to NIfTI files
post_transforms(d)
def main():
logging.basicConfig(stream=sys.stdout, level=logging.INFO)
print_config()
# Setup directories
dirs = setup_directories()
# Setup torch device
device, using_gpu = create_device("cuda")
# Load and randomize images
# HACKATON image and segmentation data
hackathon_dir = os.path.join(dirs["data"], 'HACKATHON')
map_fn = lambda x: (x[0], int(x[1]))
with open(os.path.join(hackathon_dir, "train.txt"), 'r') as fp:
train_info_hackathon = [
map_fn(entry.strip().split(',')) for entry in fp.readlines()
]
image_dir = os.path.join(hackathon_dir, 'images', 'train')
seg_dir = os.path.join(hackathon_dir, 'segmentations', 'train')
_train_data_hackathon = get_data_from_info(image_dir,
seg_dir,
train_info_hackathon,
dual_output=False)
_train_data_hackathon = large_image_splitter(_train_data_hackathon,
dirs["cache"])
copy_list = transform_and_copy(_train_data_hackathon, dirs['cache'])
balance_training_data2(_train_data_hackathon, copy_list, seed=72)
# PSUF data
"""psuf_dir = os.path.join(dirs["data"], 'psuf')
with open(os.path.join(psuf_dir, "train.txt"), 'r') as fp:
train_info = [entry.strip().split(',') for entry in fp.readlines()]
image_dir = os.path.join(psuf_dir, 'images')
train_data_psuf = get_data_from_info(image_dir, None, train_info)"""
# Split data into train, validate and test
train_split, test_data_hackathon = train_test_split(_train_data_hackathon,
test_size=0.2,
shuffle=True,
random_state=42)
train_data_hackathon, valid_data_hackathon = train_test_split(
train_split, test_size=0.2, shuffle=True, random_state=43)
#balance_training_data(train_data_hackathon, seed=72)
#balance_training_data(valid_data_hackathon, seed=73)
#balance_training_data(test_data_hackathon, seed=74)
# Setup transforms
# Crop foreground
crop_foreground = CropForegroundd(keys=["image"],
source_key="image",
margin=(5, 5, 0),
select_fn=lambda x: x != 0)
# Crop Z
crop_z = RelativeCropZd(keys=["image"], relative_z_roi=(0.07, 0.12))
# Window width and level (window center)
WW, WL = 1500, -600
ct_window = CTWindowd(keys=["image"], width=WW, level=WL)
# Random axis flip
rand_x_flip = RandFlipd(keys=["image"], spatial_axis=0, prob=0.50)
rand_y_flip = RandFlipd(keys=["image"], spatial_axis=1, prob=0.50)
rand_z_flip = RandFlipd(keys=["image"], spatial_axis=2, prob=0.50)
# Rand affine transform
rand_affine = RandAffined(keys=["image"],
prob=0.5,
rotate_range=(0, 0, np.pi / 12),
shear_range=(0.07, 0.07, 0.0),
translate_range=(0, 0, 0),
scale_range=(0.07, 0.07, 0.0),
padding_mode="zeros")
# Pad image to have hight at least 30
spatial_pad = SpatialPadd(keys=["image"], spatial_size=(-1, -1, 30))
resize = Resized(keys=["image"],
spatial_size=(int(512 * 0.50), int(512 * 0.50), -1),
mode="trilinear")
# Apply Gaussian noise
rand_gaussian_noise = RandGaussianNoised(keys=["image"],
prob=0.25,
mean=0.0,
std=0.1)
# Create transforms
common_transform = Compose([
LoadImaged(keys=["image"]),
ct_window,
CTSegmentation(keys=["image"]),
AddChanneld(keys=["image"]),
resize,
crop_foreground,
crop_z,
spatial_pad,
])
hackathon_train_transform = Compose([
common_transform,
rand_x_flip,
rand_y_flip,
rand_z_flip,
rand_affine,
rand_gaussian_noise,
ToTensord(keys=["image"]),
]).flatten()
hackathon_valid_transfrom = Compose([
common_transform,
#rand_x_flip,
#rand_y_flip,
#rand_z_flip,
#rand_affine,
ToTensord(keys=["image"]),
]).flatten()
hackathon_test_transfrom = Compose([
common_transform,
ToTensord(keys=["image"]),
]).flatten()
psuf_transforms = Compose([
LoadImaged(keys=["image"]),
AddChanneld(keys=["image"]),
ToTensord(keys=["image"]),
])
# Setup data
#set_determinism(seed=100)
train_dataset = PersistentDataset(data=train_data_hackathon[:],
transform=hackathon_train_transform,
cache_dir=dirs["persistent"])
valid_dataset = PersistentDataset(data=valid_data_hackathon[:],
transform=hackathon_valid_transfrom,
cache_dir=dirs["persistent"])
test_dataset = PersistentDataset(data=test_data_hackathon[:],
transform=hackathon_test_transfrom,
cache_dir=dirs["persistent"])
train_loader = DataLoader(
train_dataset,
batch_size=4,
#shuffle=True,
pin_memory=using_gpu,
num_workers=2,
sampler=ImbalancedDatasetSampler(
train_data_hackathon,
callback_get_label=lambda x, i: x[i]['_label']),
collate_fn=PadListDataCollate(Method.SYMMETRIC, NumpyPadMode.CONSTANT))
valid_loader = DataLoader(
valid_dataset,
batch_size=4,
shuffle=False,
pin_memory=using_gpu,
num_workers=2,
sampler=ImbalancedDatasetSampler(
valid_data_hackathon,
callback_get_label=lambda x, i: x[i]['_label']),
collate_fn=PadListDataCollate(Method.SYMMETRIC, NumpyPadMode.CONSTANT))
test_loader = DataLoader(test_dataset,
batch_size=4,
shuffle=False,
pin_memory=using_gpu,
num_workers=2,
collate_fn=PadListDataCollate(
Method.SYMMETRIC, NumpyPadMode.CONSTANT))
# Setup network, loss function, optimizer and scheduler
network = nets.DenseNet121(spatial_dims=3, in_channels=1,
out_channels=1).to(device)
# pos_weight for class imbalance
_, n, p = calculate_class_imbalance(train_data_hackathon)
pos_weight = torch.Tensor([n, p]).to(device)
loss_function = torch.nn.BCEWithLogitsLoss(pos_weight)
optimizer = torch.optim.Adam(network.parameters(), lr=1e-4, weight_decay=0)
scheduler = torch.optim.lr_scheduler.ExponentialLR(optimizer,
gamma=0.95,
last_epoch=-1)
# Setup validator and trainer
valid_post_transforms = Compose([
Activationsd(keys="pred", sigmoid=True),
#Activationsd(keys="pred", softmax=True),
])
validator = Validator(device=device,
val_data_loader=valid_loader,
network=network,
post_transform=valid_post_transforms,
amp=using_gpu,
non_blocking=using_gpu)
trainer = Trainer(device=device,
out_dir=dirs["out"],
out_name="DenseNet121",
max_epochs=120,
validation_epoch=1,
validation_interval=1,
train_data_loader=train_loader,
network=network,
optimizer=optimizer,
loss_function=loss_function,
lr_scheduler=None,
validator=validator,
amp=using_gpu,
non_blocking=using_gpu)
"""x_max, y_max, z_max, size_max = 0, 0, 0, 0
for data in valid_loader:
image = data["image"]
label = data["label"]
print()
print(len(data['image_transforms']))
#print(data['image_transforms'])
print(label)
shape = image.shape
x_max = max(x_max, shape[-3])
y_max = max(y_max, shape[-2])
z_max = max(z_max, shape[-1])
size = int(image.nelement()*image.element_size()/1024/1024)
size_max = max(size_max, size)
print("shape:", shape, "size:", str(size)+"MB")
#multi_slice_viewer(image[0, 0, :, :, :], str(label))
print(x_max, y_max, z_max, str(size_max)+"MB")
exit()"""
# Run trainer
train_output = trainer.run()
# Setup tester
tester = Tester(device=device,
test_data_loader=test_loader,
load_dir=train_output,
out_dir=dirs["out"],
network=network,
post_transform=valid_post_transforms,
non_blocking=using_gpu,
amp=using_gpu)
# Run tester
tester.run()
