Exemple #1
0
    def get_variants(self, project_id, variant_filter=None):

        variant_filter_t = VariantFilter(**(variant_filter if variant_filter else {}))

        db_query = _make_db_query(None, variant_filter)
        collection = self._get_project_collection(project_id)
        for variant_dict in collection.find(db_query).sort('xpos'):
            variant = Variant.fromJSON(variant_dict)
            if variant_filter is None:
                yield variant
            if passes_variant_filter(variant, variant_filter_t)[0]:
                yield variant
Exemple #2
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    def get_variants_in_gene(self, project_id, gene_id, variant_filter=None):

        if variant_filter is None:
            modified_variant_filter = {}
        else:
            modified_variant_filter = copy.deepcopy(variant_filter)

        if variant_filter is None:
            modified_variant_filter = VariantFilter()
        else:
            modified_variant_filter = copy.deepcopy(variant_filter)
        modified_variant_filter.add_gene(gene_id)

        db_query = _make_db_query(None, modified_variant_filter)
        collection = self._get_project_collection(project_id)

        variants = []
        for variant_dict in collection.find(db_query).hint([('gene_ids', pymongo.ASCENDING), ('xpos', pymongo.ASCENDING)]):
            variant = Variant.fromJSON(variant_dict)
            if passes_variant_filter(variant, modified_variant_filter):
                variants.append(variant)
        variants = sorted(variants, key=lambda v: v.unique_tuple())
        return variants