Exemple #1
0
coding_dna = Seq(Refseq1, generic_dna)
coding_dna.translate()

str(coding_dna.translate())

seq = ''
for i in range(len(Refseq1)):
    seq += Refseq1[i]
    
    
typing1 = 'A*23:17'
typing2 = 'A*23:01:01'
HLAtyping = typing1+'_'+typing2
Exons = 'Exon1, Exon2, Exon3, Exon4, Exon5, Exon6, Exon7, Exon8'
IMGTdbIO.checkSynonymMutation(HLAtyping, Exons, db_fp = '../Database/')


################## 
## Check Synonymous
#################
out_fp = '../Output/Stats/allLoci_paired_cases/'
Loci_num = 'AllLoci'
for locus in All_loci:
    for Allele, Item in AllField_allele_stats[locus].items():
        if Item['ARS']
    AllField_allele_stats[locus]
    TwoField_allele_stats[locus]        
            
            
            
Exemple #2
0
                                AllField_allele_stats[locus][FullField][
                                    'ARS'].append(caseID)
                                TwoField_allele_stats[locus][TwoField][
                                    'ARS'].append(caseID)

                                #ExonList = [exn.split('.')[0] for exn in Records[locus][ps]['ARS']]
                                #ExonList = list(set(ExonList))
                                #Exons = ''
                                #for i in range(len(ExonList)):
                                #    if i == 0:
                                #        Exons += ExonList[i]
                                #    else:
                                #        Exons += ', ' + ExonList[i]

                                if not IMGTdbIO.checkSynonymMutation(
                                        FullField, 'Exon1, Exon2, Exon3',
                                        db_fp):  # non-synonymous
                                    AllField_allele_stats[locus][FullField][
                                        'ARS_nonSynonymous'].append(caseID)
                                    TwoField_allele_stats[locus][TwoField][
                                        'ARS_nonSynonymous'].append(caseID)

                            if len(Records[locus][ps]['non_ARS_exon']) > 0:
                                AllField_allele_stats[locus][FullField][
                                    'non_ARS_exon'].append(caseID)
                                TwoField_allele_stats[locus][TwoField][
                                    'non_ARS_exon'].append(caseID)

                                ExonList = [
                                    exn.split('.')[0] for exn in Records[locus]
                                    [ps]['non_ARS_exon']