def main(args): a_file = open("../doc/pickle/alignment.pickle", "r") # Load the 5-way alignment alignment = pickle.load(a_file) # Close relevant files a_file.close() skip = [1, 2, 3, 4, 5, 6] pvals = [-9, -10] len1 = 0 len2 = 0 f1 = "" f2 = "" offset = 0 for j in pvals: #if j == -9: offset = 60 #else: offset = 0 print "Doing pval " + str(j) pwms = [] pwmsShuffled = [] for i in range(111): if i+1 < 10: pwms.append("MA000" + str(i+1) + "(p " + str(j) + ").gff") pwmsShuffled.append("MA000" + str(i+1) + "random(p " + str(j) + ").gff") elif i+1 < 100: pwms.append("MA00" + str(i+1) + "(p " + str(j) + ").gff") pwmsShuffled.append("MA00" + str(i+1) + "random(p " + str(j) + ").gff") else: pwms.append("MA0" + str(i+1) + "(p " + str(j) + ").gff") pwmsShuffled.append("MA0" + str(i+1) + "random(p " + str(j) + ").gff") for i in range(len(pwms)-offset): f1 = open("../doc/fasta/" + pwms[i+offset], "r") f2 = open("../doc/fasta/" + pwmsShuffled[i+offset], "r") m1 = cm_scan3.buildMotifs(f1, alignment) m2 = cm_scan3.buildMotifs(f2, alignment) len1 = len(m1) len2 = len(m2) f1.close() f2.close() try: print len1, len2 if len1 != 0 and len2 != 0: print pwms[i+offset] cm_scan3NA.mainRunner(pwms[i+offset], m1, min([len1, len2]), "LL all PWM pval " + str(j) + "/") print pwmsShuffled[i+offset] cm_scan3NA.mainRunner(pwmsShuffled[i+offset], m2, min([len1, len2]), "LL all PWMRandom pval " + str(j) + "/") else: print "NO HITS" except KeyError: print "\t\tkey problem", pwms[i+offset] sys.exit(0)
def main(args): a_file = open("../doc/pickle/alignment.pickle", "r") # Load the 5-way alignment alignment = pickle.load(a_file) # Close relevant files a_file.close() skip = [0, 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25] pvals = [-9, -10] len1 = 0 f1 = "" for j in pvals: print "Doing pval " + str(j) pwms = [] for i in range(111): if i+1 < 10: pwms.append("MA000" + str(i+1)) elif i+1 < 100: pwms.append("MA00" + str(i+1)) else: pwms.append("MA0" + str(i+1)) for s in skip: for i in range(len(pwms)): f1 = open("../doc/fasta/" + pwms[i] + "(p " + str(j) + ").gff", "r") m1 = cm_scan3.buildMotifs(f1, alignment) len1 = findLength(pwms[i] + ".pwm") f1.close() print len(m1) if len1 > s+1: try: if len(m1) != 0: print pwms[i] cm_scan3NA.mainRunner(pwms[i] + "(p " + str(j) + ").gff", m1, len(m1), "LL all PWM pval " + str(j) + " NA " + str(s) + "/", s) else: print "NO HITS" except KeyError: print "\t\tkey problem", pwms[i] makeGraphs.make("LL all PWM pval " + str(j) + " NA " + str(s) + "/", j, s) cm_scanTester2.mainRunner(s, j) sys.exit(0)