Esempio n. 1
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def default_numeric_models():
    from epipack import EpiModel
    import matplotlib.pyplot as pl
    from epipack.plottools import plot
    import numpy as np

    S, I, R = list("SIR")
    N = 1000

    SIRS = EpiModel([S,I,R],N)\
        .set_processes([
            #### transmission process ####
            # S + I (eta=2.5/d)-> I + I
            (S, I, 2.5, I, I),

            #### transition processes ####
            # I (rho=1/d)-> R
            # R (omega=1/14d)-> S
            (I, 1, R),
            (R, 1/14, S),
        ])\
        .set_initial_conditions({S:N-10, I:10})

    t = np.linspace(0, 40, 1000)
    result_int = SIRS.integrate(t)
    t_sim, result_sim = SIRS.simulate(t[-1])

    ax = plot(t_sim, result_sim)
    ax = plot(t, result_int, ax=ax)
    ax.get_figure().savefig('numeric_model.png', dpi=300)
Esempio n. 2
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def symbolic_simulation_temporally_forced():
    from epipack import SymbolicEpiModel
    import sympy as sy
    from epipack.plottools import plot
    import numpy as np

    S, I, R, eta, rho, omega, t, T = \
            sy.symbols("S I R eta rho omega t T")

    N = 1000
    SIRS = SymbolicEpiModel([S,I,R],N)\
        .set_processes([
            (S, I, 3+sy.cos(2*sy.pi*t/T), I, I),
            (I, rho, R),
            (R, omega, S),
        ])

    SIRS.set_parameter_values({
        rho: 1,
        omega: 1 / 14,
        T: 100,
    })
    SIRS.set_initial_conditions({S: N - 100, I: 100})
    _t = np.linspace(0, 150, 1000)
    result = SIRS.integrate(_t)
    t_sim, result_sim = SIRS.simulate(max(_t))

    ax = plot(_t, result)
    plot(t_sim, result_sim, ax=ax)
    ax.get_figure().savefig('symbolic_model_time_varying_rate.png', dpi=300)
Esempio n. 3
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def varying_rate_numeric_models():

    import numpy as np
    from epipack import SISModel
    from epipack.plottools import plot

    N = 100
    recovery_rate = 1.0

    def infection_rate(t, y, *args, **kwargs):
        return 3 + np.sin(2 * np.pi * t / 100)

    SIS = SISModel(
                infection_rate=infection_rate,
                recovery_rate=recovery_rate,
                initial_population_size=N
                )\
            .set_initial_conditions({
                'S': 90,
                'I': 10,
            })

    t = np.arange(200)
    result_int = SIS.integrate(t)
    t_sim, result_sim = SIS.simulate(199)

    ax = plot(t_sim, result_sim)
    ax = plot(t, result_int, ax=ax)
    ax.get_figure().savefig('numeric_model_time_varying_rate.png', dpi=300)
Esempio n. 4
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def network_simulation():
    from epipack import StochasticEpiModel
    from epipack.plottools import plot
    import matplotlib.pyplot as pl
    import networkx as nx

    k0 = 50
    R0 = 2.5
    rho = 1
    eta = R0 * rho / k0
    omega = 1 / 14
    N = int(1e4)
    edges = [ (e[0], e[1], 1.0) for e in \
              nx.fast_gnp_random_graph(N,k0/(N-1)).edges() ]

    SIRS = StochasticEpiModel(
                compartments=list('SIR'),
                N=N,
                edge_weight_tuples=edges
                )\
            .set_link_transmission_processes([
                ('I', 'S', eta, 'I', 'I'),
            ])\
            .set_node_transition_processes([
                ('I', rho, 'R'),
                ('R', omega, 'S'),
            ])\
            .set_random_initial_conditions({
                                            'S': N-100,
                                            'I': 100
                                           })
    t_s, result_s = SIRS.simulate(40)

    ax = plot(t_s, result_s)
    ax.get_figure().savefig('network_simulation.png', dpi=300)
Esempio n. 5
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    (2.25, 2.78),
    (3.0,  2.14),
    (3.75, 1.43),
    (4.5,  1.02),
    (5.25, 1.14),
    (6.0,  1.72),
])

times, rates = data[:,0], data[:,1]

f = get_temporal_interpolation(times, rates, interpolation_degree=1)

S, I, R, t, rho = sympy.symbols("S I R t rho")

model = SymbolicEpiModel([S,I,R])
model.set_processes([
        (S, I, f, I, I),
        (I, rho, R),
    ])\
    .set_initial_conditions({S:0.99,I:0.01})\
    .set_parameter_values({rho:1})

t = np.linspace(0,6,1000)

result = model.integrate(t)
ax = plot(t,result)
ax.legend()
ax.get_figure().savefig('interp_SIR_symbolic.png',dpi=300)
pl.show()

Esempio n. 6
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f = interp1d(times, rates, kind='linear', bounds_error=False)

def infection_rate(t,y):
    return f(t)

model = EpiModel(list("SIR"))
model.set_processes([
        ('S', 'I', infection_rate, 'I', 'I'),
        ('I', 1.0, 'R'),
    ])\
    .set_initial_conditions({'S':0.99,'I':0.01})\

t = np.linspace(0,6,1000)

result = model.integrate(t)
ax = plot(t,result)
ax.legend(frameon=False)

model = EpiModel(list("SIR"))
model.set_processes([
        ('S', 'I', 2.0, 'I', 'I'),
        ('I', 1.0, 'R'),
    ])\
    .set_initial_conditions({'S':0.99,'I':0.01})\

t = np.linspace(0,6,1000)

result = model.integrate(t,return_compartments='I')
ax = plot(t,result,ax=ax,curve_label_format='constant rate {}')
ax.set_ylim([0,1])
ax.legend(frameon=False)