def get_Izh_component():
subthreshold_regime = al.Regime(
name="subthreshold_regime",
time_derivatives=[
"dV/dt = 0.04*V*V + 5*V + 140.0 - U + Isyn",
"dU/dt = a*(b*V - U)",
],
transitions=[
al.On("V > theta",
do=[
"V = c",
"U = U+ d",
al.OutputEvent('spike'),
],
to='subthreshold_regime')
])
ports = [
al.AnalogSendPort("V"),
al.AnalogReducePort("Isyn", reduce_op="+")
]
c1 = al.DynamicsClass(name="Izhikevich",
regimes=[subthreshold_regime],
analog_ports=ports)
return c1
def get_component():
iaf = al.dynamics.DynamicsClass(
name="iaf",
regimes=[
al.Regime(
name="subthresholdregime",
time_derivatives=["dV/dt = ( gl*( vrest - V ) + ISyn)/(cm)"],
transitions=al.On("V > vthresh",
do=[
"tspike = t", "V = vreset",
al.OutputEvent('spikeoutput')
],
to="refractoryregime"),
),
al.Regime(
name="refractoryregime",
time_derivatives=["dV/dt = 0"],
transitions=[
al.On("t >= tspike + taurefrac", to="subthresholdregime")
],
)
],
state_variables=[
al.StateVariable('V'),
al.StateVariable('tspike'),
],
analog_ports=[
al.AnalogSendPort("V"),
al.AnalogReducePort("ISyn", reduce_op="+"),
],
event_ports=[
al.EventSendPort('spikeoutput'),
],
parameters=['cm', 'taurefrac', 'gl', 'vreset', 'vrest', 'vthresh'])
return iaf
def get_HH_component():
"""A Hodgkin-Huxley single neuron model.
Written by Andrew Davison.
See http://phobos.incf.ki.se/src_rst/examples/examples_al_python.html#example-hh
"""
aliases = [
"q10 := 3.0**((celsius - 6.3)/10.0)", # temperature correction factor
"alpha_m := -0.1*(V+40.0)/(exp(-(V+40.0)/10.0) - 1.0)", # m
"beta_m := 4.0*exp(-(V+65.0)/18.0)",
"mtau := 1/(q10*(alpha_m + beta_m))",
"minf := alpha_m/(alpha_m + beta_m)",
"alpha_h := 0.07*exp(-(V+65.0)/20.0)", # h
"beta_h := 1.0/(exp(-(V+35)/10.0) + 1.0)",
"htau := 1.0/(q10*(alpha_h + beta_h))",
"hinf := alpha_h/(alpha_h + beta_h)",
"alpha_n := -0.01*(V+55.0)/(exp(-(V+55.0)/10.0) - 1.0)", # n
"beta_n := 0.125*exp(-(V+65.0)/80.0)",
"ntau := 1.0/(q10*(alpha_n + beta_n))",
"ninf := alpha_n/(alpha_n + beta_n)",
"gna := gnabar*m*m*m*h", #
"gk := gkbar*n*n*n*n",
"ina := gna*(ena - V)", # currents
"ik := gk*(ek - V)",
"il := gl*(el - V )"
]
hh_regime = al.Regime("dn/dt = (ninf-n)/ntau",
"dm/dt = (minf-m)/mtau",
"dh/dt = (hinf-h)/htau",
"dV/dt = (ina + ik + il + Isyn)/C",
transitions=al.On("V > theta",
do=al.SpikeOutputEvent()))
# the rest are not "parameters" but aliases, assigned vars, state vars,
# indep vars, analog_analog_ports, etc.
parameters = [
'el', 'C', 'ek', 'ena', 'gkbar', 'gnabar', 'theta', 'gl', 'celsius'
]
analog_ports = [
al.AnalogSendPort("V"),
al.AnalogReducePort("Isyn", reduce_op="+")
]
c1 = al.DynamicsClass("HodgkinHuxley",
parameters=parameters,
regimes=(hh_regime, ),
aliases=aliases,
analog_ports=analog_ports)
return c1
def get_component():
coba = al.dynamics.DynamicsClass(
name="CobaSyn",
aliases=["I:=g*(vrev-V)", ],
regimes=[
al.Regime(
name="cobadefaultregime",
time_derivatives=["dg/dt = -g/tau", ],
transitions=al.On('spikeinput', do=["g=g+q"]),
)
],
state_variables=[al.StateVariable('g')],
analog_ports=[al.AnalogReceivePort("V"), al.AnalogSendPort("I"), ],
parameters=['tau', 'q', 'vrev']
)
return coba
name="refractoryRegime",
time_derivatives=["dV/dt = 0"],
transitions=[
al.On(
"t > t_rpend",
#do=[al.OutputEvent('refractoryEnd')],
to="subthresholdRegime")
],
)
],
state_variables=[
al.StateVariable('V', dimension=voltage),
al.StateVariable('t_rpend', dimension=time)
],
analog_ports=[
al.AnalogSendPort("V", dimension=voltage),
al.AnalogSendPort("t_rpend", dimension=time),
al.AnalogReducePort("Isyn", reduce_op="+", dimension=current)
],
event_ports=[
al.EventSendPort('spikeOutput'),
],
parameters=[
al.Parameter('tau', time),
al.Parameter('theta', voltage),
al.Parameter('tau_rp', time),
al.Parameter('Vreset', voltage),
al.Parameter('R', resistance)
])
if __name__ == "__main__":
import nineml.abstraction_layer as al
from nineml.abstraction_layer.units import current
model = al.DynamicsClass(
name="StaticConnection",
regimes=[al.Regime(
name="default",
time_derivatives=["dweight/dt = 0"],
)],
state_variables=[
al.StateVariable(
'weight',
dimension=current), # would be nice to make this dimensionless
],
analog_ports=[al.AnalogSendPort("weight", dimension=current)],
)
if __name__ == "__main__":
from nineml.abstraction_layer.dynamics.writers import XMLWriter
filename = __file__[0].upper() + __file__[1:].replace(".py", ".xml")
XMLWriter.write(model, filename)
from nineml.abstraction_layer.units import current, time
model = al.DynamicsClass(
name="AlphaPSR",
aliases=["Isyn := A"],
regimes=[
al.Regime(
name="default",
time_derivatives=["dA/dt = B - A/tau_syn", "dB/dt = (-B)/tau_syn"],
transitions=al.On(
'spike', do=["B = B + q"]
), # would be nice to allow constant quantities, so we could make q dimensionless
)
],
state_variables=[
al.StateVariable('A', dimension=current),
al.StateVariable('B', dimension=current),
],
analog_ports=[
al.AnalogSendPort("Isyn", dimension=current),
al.AnalogSendPort("A", dimension=current),
al.AnalogSendPort("B", dimension=current),
al.AnalogReceivePort("q", dimension=current)
],
parameters=[al.Parameter('tau_syn', dimension=time)])
if __name__ == "__main__":
from nineml.abstraction_layer.dynamics.writers import XMLWriter
filename = __file__[0].upper() + __file__[1:].replace(".py", ".xml")
XMLWriter.write(model, filename)