def __init__(self):
super().__init__()
self.data = None
common_options = dict(labelWidth=60,
orientation=Qt.Horizontal,
valueType=str,
contentsLength=14)
box = gui.vBox(self.controlArea, "Reducer configuration")
gui.comboBox(box,
self,
"reducer",
items=self.methods,
callback=self.cb_reducer_onchange,
label="Method :",
**common_options)
dmod = itemmodels.DomainModel
self.column_model = itemmodels.DomainModel(dmod.MIXED,
valid_types=dmod.PRIMITIVE)
self.cb_column = gui.comboBox(box,
self,
"column",
label="Column :",
callback=self.cb_column_onchange,
model=self.column_model,
**common_options)
gui.rubber(self.controlArea)
self.content = gui.vBox(self.mainArea)
self.content.setStyleSheet(
"background-color:white;font-size:32px;padding:10px;")
self.resultText = gui.QLabel()
self.content.layout().addWidget(self.resultText,
0,
alignment=Qt.AlignCenter
| Qt.AlignVCenter)
self.resultText.setText(str(self.result))
def __init__(self):
OWWidget.__init__(self)
ConcurrentWidgetMixin.__init__(self)
# ATTRIBUTES #
self.target_database = ENTREZ_ID
# input data
self.input_data = None
self.input_genes = None
self.tax_id = None
self.column_candidates = []
# input options
self.organisms = []
# gene matcher
self.gene_matcher = None
# progress bar
self.progress_bar = None
self._timer = QTimer()
self._timer.timeout.connect(self._apply_filter)
self._timer.setSingleShot(True)
# GUI SECTION #
# Control area
self.info_box = widgetLabel(
widgetBox(self.controlArea, "Info", addSpace=True),
'No data on input.\n')
organism_box = vBox(self.controlArea, 'Organism')
self.organism_select_combobox = comboBox(
organism_box,
self,
'selected_organism',
callback=self.on_input_option_change)
self.get_available_organisms()
self.organism_select_combobox.setCurrentIndex(self.selected_organism)
box = widgetBox(self.controlArea, 'Gene IDs in the input data')
self.gene_columns_model = itemmodels.DomainModel(
valid_types=(StringVariable, DiscreteVariable))
self.gene_column_combobox = comboBox(
box,
self,
'selected_gene_col',
label='Stored in data column',
model=self.gene_columns_model,
sendSelectedValue=True,
callback=self.on_input_option_change,
)
self.attr_names_checkbox = checkBox(
box,
self,
'use_attr_names',
'Stored as feature (column) names',
disables=[(-1, self.gene_column_combobox)],
callback=self.on_input_option_change,
)
self.gene_column_combobox.setDisabled(bool(self.use_attr_names))
output_box = vBox(self.controlArea, 'Output')
# separator(output_box)
# output_box.layout().addWidget(horizontal_line())
# separator(output_box)
self.exclude_radio = checkBox(output_box,
self,
'exclude_unmatched',
'Exclude unmatched genes',
callback=self.commit)
self.replace_radio = checkBox(output_box,
self,
'replace_id_with_symbol',
'Replace feature IDs with gene names',
callback=self.commit)
auto_commit(self.controlArea,
self,
"auto_commit",
"&Commit",
box=False)
rubber(self.controlArea)
# Main area
self.filter = lineEdit(self.mainArea,
self,
'search_pattern',
'Filter:',
callbackOnType=True,
callback=self.handle_filter_callback)
# rubber(self.radio_group)
self.mainArea.layout().addWidget(self.filter)
# set splitter
self.splitter = QSplitter()
self.splitter.setOrientation(Qt.Vertical)
self.table_model = GeneInfoModel()
self.table_view = QTableView()
self.table_view.setAlternatingRowColors(True)
self.table_view.viewport().setMouseTracking(True)
self.table_view.setSortingEnabled(True)
self.table_view.setShowGrid(False)
self.table_view.verticalHeader().hide()
# self.table_view.horizontalHeader().setSectionResizeMode(QHeaderView.Stretch)
self.unknown_model = UnknownGeneInfoModel()
self.unknown_view = QTableView()
self.unknown_view.setModel(self.unknown_model)
self.unknown_view.verticalHeader().hide()
self.unknown_view.setShowGrid(False)
self.unknown_view.setSelectionMode(QAbstractItemView.NoSelection)
self.unknown_view.horizontalHeader().setSectionResizeMode(
QHeaderView.Stretch)
self.splitter.addWidget(self.table_view)
self.splitter.addWidget(self.unknown_view)
self.splitter.setStretchFactor(0, 90)
self.splitter.setStretchFactor(1, 10)
self.mainArea.layout().addWidget(self.splitter)
def __init__(self):
super().__init__()
# widget attributes
self.input_data = None
self.store_input_domain = None
self.input_genes_names = []
self.input_genes_ids = []
self.tax_id = None
self.use_attr_names = None
self.gene_id_attribute = None
# custom gene set input
self.feature_model = itemmodels.DomainModel(
valid_types=(DiscreteVariable, StringVariable))
self.custom_data = None
self.custom_tax_id = None
self.custom_use_attr_names = None
self.custom_gene_id_attribute = None
self.custom_gene_id_column = None
self.num_of_custom_sets = None
self.rows_by_cluster = None
self.rows_by_batch = None
self.clusters = []
self.new_cluster_profile = []
# data model
self.cluster_info_model = None
# Info
info_box = vBox(self.controlArea, 'Info')
self.input_info = widgetLabel(info_box)
# Cluster selection
self.cluster_indicator_model = itemmodels.DomainModel(
valid_types=(DiscreteVariable, ), separators=False)
self.cluster_indicator_box = widgetBox(self.controlArea,
'Cluster Indicator')
self.cluster_indicator_view = listView(
self.cluster_indicator_box,
self,
'cluster_indicators',
model=self.cluster_indicator_model,
selectionMode=QListWidget.MultiSelection,
callback=self.invalidate,
sizeHint=QSize(256, 70))
# Batch selection
self.batch_indicator_model = itemmodels.DomainModel(
valid_types=(DiscreteVariable, ), separators=False, placeholder="")
box = widgetBox(self.controlArea, 'Batch Indicator')
self.batch_indicator_combobox = comboBox(
box,
self,
'batch_indicator',
model=self.batch_indicator_model,
sendSelectedValue=True,
callback=self.batch_indicator_changed)
# Gene scoring
box = widgetBox(self.controlArea, 'Gene Scoring')
self.gene_scoring = GeneScoringWidget(box, self)
self.gene_scoring.set_method_selection_area('scoring_method_selection')
self.gene_scoring.set_method_design_area('scoring_method_design')
self.gene_scoring.set_test_type('scoring_test_type')
# Gene Sets widget
gene_sets_box = widgetBox(self.controlArea, "Gene Sets")
self.gs_widget = GeneSetsSelection(gene_sets_box, self,
'stored_gene_sets_selection')
self.gs_widget.hierarchy_tree_widget.itemClicked.connect(
self.__gene_sets_enrichment)
# custom gene sets area
box = vBox(self.controlArea, "Custom Gene Sets")
if self.custom_gene_set_indicator not in self.feature_model:
self.custom_gene_set_indicator = None
self.gs_label_combobox = comboBox(
box,
self,
"custom_gene_set_indicator",
sendSelectedValue=True,
model=self.feature_model,
callback=self.handle_custom_gene_sets)
self.gs_label_combobox.setDisabled(True)
# main area
splitter = QSplitter(Qt.Horizontal, self.mainArea)
self.mainArea.layout().addWidget(splitter)
genes_filter = widgetBox(splitter,
'Filter Genes',
orientation=QHBoxLayout())
spin(genes_filter,
self,
'max_gene_count',
0,
10000,
label='Count',
tooltip='Minimum genes count',
checked='use_gene_count_filter',
callback=self.filter_genes,
callbackOnReturn=True,
checkCallback=self.filter_genes)
doubleSpin(genes_filter,
self,
'max_gene_p_value',
0.0,
1.0,
0.0001,
label='p-value',
tooltip='Maximum p-value of the enrichment score',
checked='use_gene_pval_filter',
callback=self.filter_genes,
callbackOnReturn=True,
checkCallback=self.filter_genes)
doubleSpin(genes_filter,
self,
'max_gene_fdr',
0.0,
1.0,
0.0001,
label='FDR',
tooltip='Maximum false discovery rate',
checked='use_gene_fdr_filter',
callback=self.filter_genes,
callbackOnReturn=True,
checkCallback=self.filter_genes)
gene_sets_filter = widgetBox(splitter,
'Filter Gene Sets',
orientation=QHBoxLayout())
spin(gene_sets_filter,
self,
'min_gs_count',
0,
DISPLAY_GENE_SETS_COUNT,
label='Count',
tooltip='Minimum genes count',
checked='use_gs_count_filter',
callback=self.filter_gene_sets,
callbackOnReturn=True,
checkCallback=self.filter_gene_sets)
doubleSpin(gene_sets_filter,
self,
'max_gs_p_value',
0.0,
1.0,
0.0001,
label='p-value',
tooltip='Maximum p-value of the enrichment score',
checked='use_gs_pval_filter',
callback=self.filter_gene_sets,
callbackOnReturn=True,
checkCallback=self.filter_gene_sets)
doubleSpin(gene_sets_filter,
self,
'max_gs_fdr',
0.0,
1.0,
0.0001,
label='FDR',
tooltip='Maximum false discovery rate',
checked='use_gs_max_fdr',
callback=self.filter_gene_sets,
callbackOnReturn=True,
checkCallback=self.filter_gene_sets)
self.cluster_info_view = QTableView()
self.cluster_info_view.verticalHeader().setVisible(False)
self.cluster_info_view.setItemDelegate(HTMLDelegate())
self.cluster_info_view.horizontalHeader().hide()
self.cluster_info_view.horizontalHeader().setSectionResizeMode(
QHeaderView.Stretch)
auto_commit(self.controlArea,
self,
"auto_commit",
"&Commit",
box=False)
self.mainArea.layout().addWidget(self.cluster_info_view)
def __init__(self):
super().__init__()
# ATTRIBUTES #
# input data
self.input_data = None
self.input_genes = None
self.tax_id = None
self.column_candidates = []
self.selected_gene_col = None
# input options
self.organisms = []
# gene matcher
self.gene_matcher = None
# threads
self.threadpool = QThreadPool(self)
self.workers = None
# progress bar
self.progress_bar = None
# filter
self.filter_labels = ['Unique', 'Partial', 'Unknown']
# GUI SECTION #
# Control area
self.info_box = widgetLabel(
widgetBox(self.controlArea, "Info", addSpace=True),
"Initializing\n")
organism_box = vBox(self.controlArea, 'Organism')
self.organism_select_combobox = comboBox(
organism_box,
self,
'selected_organism',
callback=self.on_input_option_change)
self.get_available_organisms()
self.organism_select_combobox.setCurrentIndex(self.selected_organism)
box = widgetBox(self.controlArea, 'Gene names')
self.gene_columns_model = itemmodels.DomainModel(
valid_types=(StringVariable, ))
self.gene_column_combobox = comboBox(
box,
self,
'selected_gene_col',
model=self.gene_columns_model,
sendSelectedValue=True,
callback=self.on_input_option_change)
self.attr_names_checkbox = checkBox(
box,
self,
'use_attr_names',
'Use attribute names',
disables=[(-1, self.gene_column_combobox)],
callback=self.on_input_option_change)
self.gene_column_combobox.setDisabled(bool(self.use_attr_names))
output_box = vBox(self.controlArea, 'Output settings')
# TODO: will widget support transposing tables?
# radioButtonsInBox(output_box, self, "gene_as_attr_name", ["Genes in rows", "Genes in columns"],
# callback=self.on_output_option_change)
# separator(output_box)
checkBox(output_box,
self,
'filter_unknown',
'Filter unknown genes',
callback=self.on_output_option_change)
separator(output_box)
output_box.layout().addWidget(horizontal_line())
checkBox(output_box,
self,
'include_entrez_id',
'Include Entrez ID',
callback=self.on_output_option_change)
# TODO: provide support for ensembl ids as output option
# checkBox(output_box, self, 'include_ensembl_id', 'Include Ensembl ID', callback=self.on_output_option_change)
auto_commit(self.controlArea, self, "auto_commit", label="Commit")
rubber(self.controlArea)
# Main area
filter_box = hBox(self.mainArea, 'Filter results')
self.radio_group = radioButtons(filter_box,
self,
value='selected_filter',
btnLabels=self.filter_labels,
orientation=Qt.Horizontal,
callback=self.on_filter_changed)
rubber(self.radio_group)
self.mainArea.layout().addWidget(filter_box)
self.proxy_model = FilterProxyModel(self)
self.extended_view = ExtendedTableView(parent=self)
self.extended_view.genes_view.setModel(self.proxy_model)
self.extended_view.genes_selection_model().selectionChanged.connect(
self.__selection_changed)
self.mainArea.layout().addWidget(self.extended_view, 1)