コード例 #1
0
ファイル: HIPPCellTest.py プロジェクト: soltesz-lab/dentate
def ap_test(template_class, tree, v_init):

    cell = cells.make_neurotree_cell(template_class, neurotree_dict=tree)
    h.dt = 0.025

    prelength = 100.0
    stimdur = 10.0

    soma = list(cell.soma)[0]
    initial_amp = 0.05

    h.tlog = h.Vector()
    h.tlog.record(h._ref_t)

    h.Vlog = h.Vector()
    h.Vlog.record(soma(0.5)._ref_v)

    thr = cells.find_spike_threshold_minimum(cell,
                                             loc=0.5,
                                             sec=soma,
                                             duration=stimdur,
                                             initial_amp=initial_amp)

    f = open("HIPPCell_ap_results.dat", 'w')
    f.write("## current amplitude: %g\n" % thr)
    f.close()

    f = open("HIPPCell_voltage_trace.dat", 'w')
    for i in range(0, int(h.tlog.size())):
        f.write('%g %g\n' % (h.tlog.x[i], h.Vlog.x[i]))
    f.close()
コード例 #2
0
ファイル: cell_clamp.py プロジェクト: pramodk/dentate
def measure_ap (gid, pop_name, v_init, env, cell_dict={}):


    biophys_cell = init_biophys_cell(env, pop_name, gid, register_cell=False, cell_dict=cell_dict)
    hoc_cell = biophys_cell.hoc_cell

    h.dt = env.dt

    prelength = 100.0
    stimdur = 10.0
    
    soma = list(hoc_cell.soma)[0]
    initial_amp = 0.05

    h.tlog = h.Vector()
    h.tlog.record (h._ref_t)

    h.Vlog = h.Vector()
    h.Vlog.record (soma(0.5)._ref_v)

    thr = cells.find_spike_threshold_minimum(hoc_cell,loc=0.5,sec=soma,duration=stimdur,initial_amp=initial_amp)

    results = { 'spike threshold current': np.asarray([thr], dtype=np.float32),
                'spike threshold trace t': np.asarray(h.tlog.to_python(), dtype=np.float32),
                'spike threshold trace v': np.asarray(h.Vlog.to_python(), dtype=np.float32) }

    env.synapse_attributes.del_syn_id_attr_dict(gid)
    if gid in env.biophys_cells[pop_name]:
        del env.biophys_cells[pop_name][gid]

    return results