k=lambda V: 1.0e3 * 3. * beta_cap(V * 1.0e3) * Qt) CaPm2m1 = smodel.VDepSReac('CaPm2m1', ssys, slhs=[CaP_m2], srhs=[CaP_m1], k=lambda V: 1.0e3 * 2. * beta_cap(V * 1.0e3) * Qt) CaPm1m0 = smodel.VDepSReac('CaPm1m0', ssys, slhs=[CaP_m1], srhs=[CaP_m0], k=lambda V: 1.0e3 * 1. * beta_cap(V * 1.0e3) * Qt) if cyl160: OC_CaP = smodel.GHKcurr('OC_CaP', ssys, CaP_m3, Ca, virtual_oconc=Ca_oconc, computeflux=True) else: OC_CaP = smodel.GHKcurr('OC_CaP', ssys, CaP_m3, Ca, computeflux=True) OC_CaP.setP(CaP_P) ######## CaT channel ########## CaTchan = smodel.Chan('CaTchan', mdl) CaT_m0h0 = smodel.ChanState('CaT_m0h0', mdl, CaTchan) CaT_m0h1 = smodel.ChanState('CaT_m0h1', mdl, CaTchan) CaT_m1h0 = smodel.ChanState('CaT_m1h0', mdl, CaTchan) CaT_m1h1 = smodel.ChanState('CaT_m1h1', mdl, CaTchan)
k=lambda V: 1.0e3 * 3. * beta_cap(V * 1.0e3) * Qt) CaPm2m1 = smodel.VDepSReac('CaPm2m1', ssys_stoch, slhs=[CaP_m2], srhs=[CaP_m1], k=lambda V: 1.0e3 * 2. * beta_cap(V * 1.0e3) * Qt) CaPm1m0 = smodel.VDepSReac('CaPm1m0', ssys_stoch, slhs=[CaP_m1], srhs=[CaP_m0], k=lambda V: 1.0e3 * 1. * beta_cap(V * 1.0e3) * Qt) if cyl160: OC_CaP = smodel.GHKcurr('OC_CaP', ssys_stoch, CaP_m3, Ca_stoch, virtual_oconc=Ca_oconc, computeflux=True) else: OC_CaP = smodel.GHKcurr('OC_CaP', ssys_stoch, CaP_m3, Ca_stoch, computeflux=True) OC_CaP.setP(CaP_P) ######## CaT channel ########## CaT_m0h0 = smodel.Spec('CaT_m0h0', mdl_det) CaT_m0h1 = smodel.Spec('CaT_m0h1', mdl_det) CaT_m1h0 = smodel.Spec('CaT_m1h0', mdl_det)
k=lambda V: 1.0e3 * 1. * betah_cat(V * 1.0e3)) CaTm1h1_m1h0 = smodel.VDepSReac('CaTm1h1_m1h0', ssys_stoch, slhs=[CaT_m1h1], srhs=[CaT_m1h0], k=lambda V: 1.0e3 * 1. * betah_cat(V * 1.0e3)) CaTm0h1_m0h0 = smodel.VDepSReac('CaTm0h1_m0h0', ssys_stoch, slhs=[CaT_m0h1], srhs=[CaT_m0h0], k=lambda V: 1.0e3 * 1. * betah_cat(V * 1.0e3)) if cyl160: OC_CaT = smodel.GHKcurr('OC_CaT', ssys_stoch, CaT_m2h1, Ca_stoch, virtual_oconc=Ca_oconc, computeflux=True) else: OC_CaT = smodel.GHKcurr('OC_CaT', ssys_stoch, CaT_m2h1, Ca_stoch, computeflux=True) OC_CaT.setP(CaT_P) ##### BK channel #################### BK_C0 = smodel.Spec('BK_C0', mdl_det) BK_C1 = smodel.Spec('BK_C1', mdl_det) BK_C2 = smodel.Spec('BK_C2', mdl_det)