def make_hsa(self): """returns a configured organism object""" nw_factories = [stringdb.get_network_factory2('parkinson_data/human_links_preprocessed.csv', weight=1.0, sep=';')] return organism.GenericOrganism('hsa', THESAURUS_FILE, nw_factories, seq_filenames=SEQ_FILENAMES, search_distances=self['search_distances'], scan_distances=self['scan_distances'])
def make_halo(ratio_matrix, search_distances, scan_distances): """returns the organism object to work on""" keggfile = util.read_dfile(KEGG_FILE_PATH, comment='#') gofile = util.read_dfile(GO_FILE_PATH) rsatdb = rsat.RsatDatabase(rsat.RSAT_BASE_URL, CACHE_DIR) mo_db = microbes_online.MicrobesOnline(CACHE_DIR) stringfile = 'testdata/string_links_64091.tab' nw_factories = [] if stringfile != None: nw_factories.append( stringdb.get_network_factory2('hal', stringfile, 0.5, normalized=True)) else: logging.warn("no STRING file specified !") nw_factories.append( microbes_online.get_network_factory( mo_db, max_operon_size=ratio_matrix.num_rows / 20, weight=0.5)) org_factory = org.MicrobeFactory(org.make_kegg_code_mapper(keggfile), org.make_rsat_organism_mapper(rsatdb), org.make_go_taxonomy_mapper(gofile), mo_db, nw_factories) return org_factory.create('hal', search_distances, scan_distances)
def make_tps(self): """returns a tps organism object""" nw_factories = [stringdb.get_network_factory2(STRING_LINKS, 1.0)] return organism.GenericOrganism('tps', THESAURUS_FILE, nw_factories, seq_filenames=SEQ_FILENAMES, search_distances=SEARCH_DISTANCES, scan_distances=SCAN_DISTANCES)
def make_mmu(self): """returns a configured organism object""" nw_factories = [stringdb.get_network_factory2('leishmania_data/mouse_links_preprocessed.csv', weight=1.0, sep=';')] return organism.GenericOrganism('mmu', THESAURUS_FILE, nw_factories, seq_filenames=SEQ_FILENAMES, search_distances=SEARCH_DISTANCES, scan_distances=SCAN_DISTANCES)
def make_tps(self): """returns a tps organism object""" nw_factories = [stringdb.get_network_factory2(self['string_file'], 1.0)] return organism.GenericOrganism( 'tps', THESAURUS_FILE, nw_factories, seq_filenames=SEQ_FILENAMES, search_distances=self['search_distances'], scan_distances=self['scan_distances'])
def make_microbe(self): """returns the organism object to work on""" keggfile = util.read_dfile(KEGG_FILE_PATH, comment='#') gofile = util.read_dfile(GO_FILE_PATH) rsatdb = rsat.RsatDatabase(RSAT_BASE_URL, self['cache_dir']) mo_db = microbes_online.MicrobesOnline() stringfile = self.config_params['string_file'] kegg_mapper = org.make_kegg_code_mapper(keggfile) rsat_mapper = org.make_rsat_organism_mapper(rsatdb) # automatically download STRING file if stringfile == None: rsat_info = rsat_mapper(kegg_mapper(self['organism_code'])) ncbi_code = rsat_info.taxonomy_id print "NCBI CODE IS: ", ncbi_code url = STRING_URL_PATTERN % ncbi_code stringfile = "%s/%s.gz" % (self['cache_dir'], ncbi_code) self['string_file'] = stringfile logging.info("Automatically using STRING file in '%s'", stringfile) util.get_url_cached(url, stringfile) nw_factories = [] if stringfile != None: nw_factories.append(stringdb.get_network_factory2( self['organism_code'], stringfile, 0.5)) else: logging.warn("no STRING file specified !") nw_factories.append(microbes_online.get_network_factory( mo_db, max_operon_size=self.ratio_matrix.num_rows / 20, weight=0.5)) org_factory = org.MicrobeFactory(kegg_mapper, rsat_mapper, org.make_go_taxonomy_mapper(gofile), mo_db, nw_factories) return org_factory.create(self['organism_code'], self['search_distances'], self['scan_distances'])
def make_halo(ratio_matrix, search_distances, scan_distances): """returns the organism object to work on""" keggfile = util.read_dfile(KEGG_FILE_PATH, comment='#') gofile = util.read_dfile(GO_FILE_PATH) rsatdb = rsat.RsatDatabase(RSAT_BASE_URL, CACHE_DIR ) mo_db = microbes_online.MicrobesOnline() stringfile = 'string_links_64091.tab' nw_factories = [] if stringfile != None: nw_factories.append(stringdb.get_network_factory2('hal', stringfile, 0.5)) else: logging.warn("no STRING file specified !") nw_factories.append(microbes_online.get_network_factory( mo_db, max_operon_size=ratio_matrix.num_rows / 20, weight=0.5)) org_factory = org.MicrobeFactory(org.make_kegg_code_mapper(keggfile), org.make_rsat_organism_mapper(rsatdb), org.make_go_taxonomy_mapper(gofile), mo_db, nw_factories) return org_factory.create('hal', search_distances, scan_distances)
def make_microbe(self): """returns the organism object to work on""" keggfile = util.DelimitedFile.read(KEGG_FILE_PATH, comment='#') gofile = util.DelimitedFile.read(GO_FILE_PATH) rsatdb = rsat.RsatDatabase(RSAT_BASE_URL, self['cache_dir']) mo_db = microbes_online.MicrobesOnline() stringfile = self.config_params['string_file'] nw_factories = [] if stringfile != None: nw_factories.append(stringdb.get_network_factory2(stringfile, 0.5)) else: logging.warn("no STRING file specified !") nw_factories.append(microbes_online.get_network_factory( mo_db, max_operon_size=self.ratio_matrix.num_rows() / 20, weight=0.5)) org_factory = org.MicrobeFactory(org.make_kegg_code_mapper(keggfile), org.make_rsat_organism_mapper(rsatdb), org.make_go_taxonomy_mapper(gofile), mo_db, nw_factories) return org_factory.create(self['organism_code'], self['search_distances'], self['scan_distances'])
def make_microbe(self): """returns the organism object to work on""" self.__make_dirs_if_needed() if os.path.exists(USER_KEGG_FILE_PATH): keggfile = util.read_dfile(USER_KEGG_FILE_PATH, comment='#') elif os.path.exists(SYSTEM_KEGG_FILE_PATH): keggfile = util.read_dfile(SYSTEM_KEGG_FILE_PATH, comment='#') else: raise Exception('KEGG file not found !!') if os.path.exists(USER_GO_FILE_PATH): gofile = util.read_dfile(USER_GO_FILE_PATH) elif os.path.exists(SYSTEM_GO_FILE_PATH): gofile = util.read_dfile(SYSTEM_GO_FILE_PATH) else: raise Exception('GO file not found !!') if self['rsat_dir']: if not self['rsat_organism']: raise Exception( 'override RSAT loading: please specify --rsat_organism') logging.info("using RSAT files for '%s'", self['rsat_organism']) rsatdb = rsat.RsatFiles(self['rsat_dir'], self['rsat_organism'], self['ncbi_code']) else: rsatdb = rsat.RsatDatabase(rsat.RSAT_BASE_URL, self['cache_dir']) if self['operon_file']: logging.info("using operon file at '%s'", self['operon_file']) mo_db = microbes_online.MicrobesOnlineOperonFile( self['operon_file']) else: logging.info( "attempting automatic download of operons from Microbes Online" ) mo_db = microbes_online.MicrobesOnline(self['cache_dir']) stringfile = self['string_file'] kegg_mapper = org.make_kegg_code_mapper(keggfile) rsat_mapper = org.make_rsat_organism_mapper(rsatdb) ncbi_code = self['ncbi_code'] nw_factories = [] # do we use STRING ? if self['donetworks'] and self['use_string']: # download if not provided if stringfile is None: if ncbi_code is None: rsat_info = rsat_mapper(kegg_mapper(self['organism_code']), self['rsat_organism']) ncbi_code = rsat_info.taxonomy_id logging.info("NCBI CODE IS: %s", ncbi_code) url = STRING_URL_PATTERN % ncbi_code stringfile = "%s/%s.gz" % (self['cache_dir'], ncbi_code) self['string_file'] = stringfile logging.info("Automatically using STRING file in '%s'", stringfile) util.get_url_cached(url, stringfile) else: logging.info("Loading STRING file at '%s'", stringfile) # create and add network nw_factories.append( stringdb.get_network_factory2(self['organism_code'], stringfile, 0.5)) # do we use operons ? if self['donetworks'] and self['use_operons']: logging.info('adding operon network factory') nw_factories.append( microbes_online.get_network_factory( mo_db, max_operon_size=self.ratio_matrix.num_rows / 20, weight=0.5)) org_factory = org.MicrobeFactory(kegg_mapper, rsat_mapper, org.make_go_taxonomy_mapper(gofile), mo_db, nw_factories, self['ncbi_code']) return org_factory.create(self['organism_code'], self['search_distances'], self['scan_distances'], self['use_operons'], self['rsat_organism'], self.ratio_matrix)
def make_microbe(self): """returns the organism object to work on""" self.__make_dirs_if_needed() if os.path.exists(USER_KEGG_FILE_PATH): keggfile = util.read_dfile(USER_KEGG_FILE_PATH, comment='#') elif os.path.exists(SYSTEM_KEGG_FILE_PATH): keggfile = util.read_dfile(SYSTEM_KEGG_FILE_PATH, comment='#') else: raise Exception('KEGG file not found !!') if os.path.exists(USER_GO_FILE_PATH): gofile = util.read_dfile(USER_GO_FILE_PATH) elif os.path.exists(SYSTEM_GO_FILE_PATH): gofile = util.read_dfile(SYSTEM_GO_FILE_PATH) else: raise Exception('GO file not found !!') if self['rsat_dir']: if not self['rsat_organism']: raise Exception('override RSAT loading: please specify --rsat_organism') logging.info("using RSAT files for '%s'", self['rsat_organism']) rsatdb = rsat.RsatFiles(self['rsat_dir'], self['rsat_organism'], self['ncbi_code']) else: rsatdb = rsat.RsatDatabase(rsat.RSAT_BASE_URL, self['cache_dir']) if self['operon_file']: logging.info("using operon file at '%s'", self['operon_file']) mo_db = microbes_online.MicrobesOnlineOperonFile(self['operon_file']) else: logging.info("attempting automatic download of operons from Microbes Online") mo_db = microbes_online.MicrobesOnline(self['cache_dir']) stringfile = self['string_file'] kegg_mapper = org.make_kegg_code_mapper(keggfile) rsat_mapper = org.make_rsat_organism_mapper(rsatdb) ncbi_code = self['ncbi_code'] nw_factories = [] # do we use STRING ? if self['donetworks'] and self['use_string']: # download if not provided if stringfile is None: if ncbi_code is None: rsat_info = rsat_mapper(kegg_mapper(self['organism_code']), self['rsat_organism']) ncbi_code = rsat_info.taxonomy_id logging.info("NCBI CODE IS: %s", ncbi_code) url = STRING_URL_PATTERN % ncbi_code stringfile = "%s/%s.gz" % (self['cache_dir'], ncbi_code) self['string_file'] = stringfile logging.info("Automatically using STRING file in '%s'", stringfile) util.get_url_cached(url, stringfile) else: logging.info("Loading STRING file at '%s'", stringfile) # create and add network nw_factories.append(stringdb.get_network_factory2( self['organism_code'], stringfile, 0.5)) # do we use operons ? if self['donetworks'] and self['use_operons']: logging.info('adding operon network factory') nw_factories.append(microbes_online.get_network_factory( mo_db, max_operon_size=self.ratio_matrix.num_rows / 20, weight=0.5)) org_factory = org.MicrobeFactory(kegg_mapper, rsat_mapper, org.make_go_taxonomy_mapper(gofile), mo_db, nw_factories, self['ncbi_code']) return org_factory.create(self['organism_code'], self['search_distances'], self['scan_distances'], self['use_operons'], self['rsat_organism'], self.ratio_matrix)