예제 #1
0
    def commit(self):
        if self.currentGds:
            self.error(0)
            sample_type = None
            self.progressBarInit(processEvents=None)

            _, groups = self.selectedSamples()
            if len(groups) == 1 and self.outputRows:
                sample_type = groups[0]

            self.setEnabled(False)
            self.setBlocking(True)

            progress = methodinvoke(self, "progressCompleted", (int, int))

            def get_data(gds_id, report_genes, transpose, sample_type, title):
                gds_ensure_downloaded(gds_id, progress)
                gds = GDS(gds_id)
                data = gds.get_data(report_genes=report_genes,
                                    transpose=transpose,
                                    sample_type=sample_type)
                data.name = title
                return data

            get_data = partial(get_data,
                               self.currentGds["dataset_id"],
                               report_genes=self.mergeSpots,
                               transpose=self.outputRows,
                               sample_type=sample_type,
                               title=self.datasetName
                               or self.currentGds["title"])
            self._datatask = Task(function=get_data)
            self._datatask.finished.connect(self._on_dataready)
            self._executor.submit(self._datatask)
    def updateInfoItems(self):
        self.warning(0)
        if self.data is None:
            return

        if self.useAttr:
            genes = [attr.name for attr in self.data.domain.attributes]
        elif self.attributes:
            attr = self.attributes[self.gene_attr]
            genes = [
                str(ex[attr]) for ex in self.data if not math.isnan(ex[attr])
            ]
        else:
            genes = []
        if not genes:
            self.warning(0, "Could not extract genes from input dataset.")

        self.warning(1)
        org = self.organisms[min(self.organism_index, len(self.organisms) - 1)]
        source_name, info_getter = ("NCBI Info", ncbi_info)

        self.error(0)

        self.progressBarInit()
        self.setBlocking(True)
        self.setEnabled(False)
        self.infoLabel.setText("Retrieving info records.\n")

        self.genes = genes

        task = Task(function=partial(
            info_getter, org, genes, advance=methodinvoke(self, "advance", (
            ))))
        self.itemsfuture = self.executor.submit(task)
        task.finished.connect(self._onItemsCompleted)
예제 #3
0
    def commit(self):
        include_neighborhood = self.include_neighborhood
        query_genes = self.query_genes()
        source = SOURCES[self.network_source]
        if source.score_filter:
            min_score = self.min_score
            assert source.name == "STRING"
            min_score = min_score * 1000
        else:
            min_score = None

        taxid = self.taxid
        progress = methodinvoke(self, "advance")
        if self.geneinfo is None:
            self.geneinfo = self.executor.submit(fetch_ncbi_geneinfo, taxid,
                                                 progress)

        geneinfo_f = self.geneinfo
        taxmap = source.tax_mapping
        db_taxid = taxmap.get(taxid, taxid)

        if db_taxid is None:
            raise ValueError("invalid taxid for this network")

        def fetch_network():
            geneinfo = geneinfo_f.result()
            ppidb = fetch_ppidb(source, db_taxid, progress)
            return get_gene_network(ppidb,
                                    geneinfo,
                                    db_taxid,
                                    query_genes,
                                    include_neighborhood=include_neighborhood,
                                    min_score=min_score,
                                    progress=methodinvoke(
                                        self, "set_progress", (float, )))

        self.nettask = Task(function=fetch_network)
        self.nettask.finished.connect(self._on_result_ready)

        self.executor.submit(self.nettask)

        self.setBlocking(True)
        self.setEnabled(False)
        self.progressBarInit()
        self._invalidated = False
        self._update_info()
    def RetrieveFilesList(self):
        self.retryButton.hide()
        self.warning(0)
        self.progress.setRange(0, 3)

        task = Task(function=partial(retrieveFilesList, methodinvoke(self.progress, "advance")))

        task.resultReady.connect(self.SetFilesList)
        task.exceptionReady.connect(self.HandleError)

        self.executor.submit(task)

        self.setEnabled(False)
예제 #5
0
    def commit(self):
        include_neighborhood = self.include_neighborhood
        query_genes = self.query_genes()
        source = SOURCES[self.network_source]
        if source.score_filter:
            min_score = self.min_score
            assert source.name == "STRING"
            min_score = min_score * 1000
        else:
            min_score = None

        taxid = self.taxid
        progress = methodinvoke(self, "advance")
        if self.geneinfo is None:
            self.geneinfo = self.executor.submit(
                fetch_ncbi_geneinfo, taxid, progress
            )

        geneinfo_f = self.geneinfo
        taxmap = source.tax_mapping
        db_taxid = taxmap.get(taxid, taxid)

        if db_taxid is None:
            raise ValueError("invalid taxid for this network")

        def fetch_network():
            geneinfo = geneinfo_f.result()
            ppidb = fetch_ppidb(source, db_taxid, progress)
            return get_gene_network(ppidb, geneinfo, db_taxid, query_genes,
                                    include_neighborhood=include_neighborhood,
                                    min_score=min_score,
                                    progress=methodinvoke(self, "set_progress", (float,)))

        self.nettask = Task(function=fetch_network)
        self.nettask.finished.connect(self._on_result_ready)

        self.executor.submit(self.nettask)

        self.setBlocking(True)
        self.setEnabled(False)
        self.progressBarInit()
        self._invalidated = False
        self._update_info()
예제 #6
0
    def test_executor(self):
        executor = ThreadExecutor()

        f = executor.submit(QThread.currentThread)

        self.assertIsNot(f.result(3), QThread.currentThread())

        f = executor.submit(lambda: 1 / 0)

        with self.assertRaises(ZeroDivisionError):
            f.result()

        results = []
        task = Task(function=QThread.currentThread)
        task.resultReady.connect(results.append, Qt.DirectConnection)

        f = executor.submit_task(task)

        self.assertIsNot(f.result(3), QThread.currentThread())

        executor.shutdown()
예제 #7
0
    def test_task(self):
        results = []

        task = Task(function=QThread.currentThread)
        task.resultReady.connect(results.append)

        task.start()
        self.app.processEvents()

        self.assertSequenceEqual(results, [QThread.currentThread()])

        thread = QThread()
        thread.start()
        try:
            task = Task(function=QThread.currentThread)
            task.moveToThread(thread)

            self.assertIsNot(task.thread(), QThread.currentThread())
            self.assertIs(task.thread(), thread)
            results = Future()

            def record(value):
                # record the result value and the calling thread
                results.set_result((QThread.currentThread(), value))

            task.resultReady.connect(record, Qt.DirectConnection)
            task.start()
            f = task.future()
            emit_thread, thread_ = results.result(3)
            self.assertIs(f.result(3), thread)
            self.assertIs(emit_thread, thread)
            self.assertIs(thread_, thread)
        finally:
            thread.quit()
            thread.wait()
 def __init__(self, files_list, parent=None):
     Task.__init__(self, parent)
     self.files_list = files_list
예제 #9
0
    def __init__(
        self,
        parent=None,
    ):
        super().__init__(self, parent)

        self.selectionChangedFlag = False

        self.__initialized = False
        self.initfuture = None
        self.itemsfuture = None

        self.infoLabel = gui.widgetLabel(
            gui.widgetBox(self.controlArea, "Info", addSpace=True),
            "Initializing\n")

        self.organisms = None
        self.organismBox = gui.widgetBox(self.controlArea,
                                         "Organism",
                                         addSpace=True)

        self.organismComboBox = gui.comboBox(
            self.organismBox,
            self,
            "organism_index",
            callback=self._onSelectedOrganismChanged)

        # For now only support one alt source, with a checkbox
        # In the future this can be extended to multiple selections
        self.altSourceCheck = gui.checkBox(self.organismBox,
                                           self,
                                           "useAltSource",
                                           "Show information from dictyBase",
                                           callback=self.onAltSourceChange)

        self.altSourceCheck.hide()

        box = gui.widgetBox(self.controlArea, "Gene names", addSpace=True)
        self.geneAttrComboBox = gui.comboBox(box,
                                             self,
                                             "gene_attr",
                                             "Gene attribute",
                                             callback=self.updateInfoItems)
        self.geneAttrComboBox.setEnabled(not self.useAttr)
        cb = gui.checkBox(box,
                          self,
                          "useAttr",
                          "Use attribute names",
                          callback=self.updateInfoItems)
        cb.toggled[bool].connect(self.geneAttrComboBox.setDisabled)

        gui.auto_commit(self.controlArea, self, "auto_commit", "Commit")

        # A label for dictyExpress link (Why oh god why???)
        self.dictyExpressBox = gui.widgetBox(self.controlArea, "Dicty Express")
        self.linkLabel = gui.widgetLabel(self.dictyExpressBox, "")
        self.linkLabel.setOpenExternalLinks(False)
        self.linkLabel.linkActivated.connect(self.onDictyExpressLink)

        self.dictyExpressBox.hide()

        gui.rubber(self.controlArea)

        gui.lineEdit(self.mainArea,
                     self,
                     "search_string",
                     "Filter",
                     callbackOnType=True,
                     callback=self.searchUpdate)

        self.treeWidget = QTreeView(self.mainArea,
                                    selectionMode=QTreeView.ExtendedSelection,
                                    rootIsDecorated=False,
                                    uniformRowHeights=True,
                                    sortingEnabled=True)

        self.treeWidget.setItemDelegate(
            gui.LinkStyledItemDelegate(self.treeWidget))
        self.treeWidget.viewport().setMouseTracking(True)
        self.mainArea.layout().addWidget(self.treeWidget)

        box = gui.widgetBox(self.mainArea, "", orientation="horizontal")
        gui.button(box, self, "Select Filtered", callback=self.selectFiltered)
        gui.button(box,
                   self,
                   "Clear Selection",
                   callback=self.treeWidget.clearSelection)

        self.geneinfo = []
        self.cells = []
        self.row2geneinfo = {}
        self.data = None

        # : (# input genes, # matches genes)
        self.matchedInfo = 0, 0

        self.setBlocking(True)
        self.executor = ThreadExecutor(self)

        self.progressBarInit()

        task = Task(
            function=partial(taxonomy.ensure_downloaded,
                             callback=methodinvoke(self, "advance", ())))

        task.resultReady.connect(self.initialize)
        task.exceptionReady.connect(self._onInitializeError)

        self.initfuture = self.executor.submit(task)
    def __init__(
        self,
        parent=None,
    ):
        super().__init__(self, parent)

        self.selectionChangedFlag = False

        self.__initialized = False
        self.initfuture = None
        self.itemsfuture = None

        self.map_input_to_ensembl = None
        self.infoLabel = gui.widgetLabel(
            gui.widgetBox(self.controlArea, "Info", addSpace=True),
            "Initializing\n")

        self.organisms = None
        self.organismBox = gui.widgetBox(self.controlArea,
                                         "Organism",
                                         addSpace=True)

        self.organismComboBox = gui.comboBox(
            self.organismBox,
            self,
            "organism_index",
            callback=self._onSelectedOrganismChanged)

        box = gui.widgetBox(self.controlArea, "Gene names", addSpace=True)
        self.geneAttrComboBox = gui.comboBox(box,
                                             self,
                                             "gene_attr",
                                             "Gene attribute",
                                             callback=self.updateInfoItems)
        self.geneAttrComboBox.setEnabled(not self.useAttr)

        self.geneAttrCheckbox = gui.checkBox(box,
                                             self,
                                             "useAttr",
                                             "Use column names",
                                             callback=self.updateInfoItems)
        self.geneAttrCheckbox.toggled[bool].connect(
            self.geneAttrComboBox.setDisabled)

        gui.auto_commit(self.controlArea, self, "auto_commit", "Commit")

        gui.rubber(self.controlArea)

        gui.lineEdit(self.mainArea,
                     self,
                     "search_string",
                     "Filter",
                     callbackOnType=True,
                     callback=self.searchUpdate)

        self.treeWidget = QTreeView(self.mainArea)

        self.treeWidget.setAlternatingRowColors(True)
        self.treeWidget.setSortingEnabled(True)
        self.treeWidget.setSelectionMode(QTreeView.ExtendedSelection)
        self.treeWidget.setUniformRowHeights(True)
        self.treeWidget.setRootIsDecorated(False)

        self.treeWidget.setItemDelegateForColumn(
            HEADER_SCHEMA['NCBI ID'],
            gui.LinkStyledItemDelegate(self.treeWidget))
        self.treeWidget.setItemDelegateForColumn(
            HEADER_SCHEMA['Ensembl ID'],
            gui.LinkStyledItemDelegate(self.treeWidget))

        self.treeWidget.viewport().setMouseTracking(True)
        self.mainArea.layout().addWidget(self.treeWidget)

        box = gui.widgetBox(self.mainArea, "", orientation="horizontal")
        gui.button(box, self, "Select Filtered", callback=self.selectFiltered)
        gui.button(box,
                   self,
                   "Clear Selection",
                   callback=self.treeWidget.clearSelection)

        self.geneinfo = []
        self.cells = []
        self.row2geneinfo = {}
        self.data = None

        # : (# input genes, # matches genes)
        self.matchedInfo = 0, 0

        self.setBlocking(True)
        self.executor = ThreadExecutor(self)

        self.progressBarInit()

        task = Task(
            function=partial(taxonomy.ensure_downloaded,
                             callback=methodinvoke(self, "advance", ())))

        task.resultReady.connect(self.initialize)
        task.exceptionReady.connect(self._onInitializeError)

        self.initfuture = self.executor.submit(task)
 def __init__(self, domain, filename, serverfiles, parent=None):
     Task.__init__(self, parent)
     self.filename = filename
     self.domain = domain
     self.serverfiles = serverfiles
     self._interrupt = False
예제 #12
0
class OWGeneNetwork(widget.OWWidget):
    name = "Gene Network"
    description = "Extract a gene network for a set of genes."
    icon = "../widgets/icons/GeneNetwork.svg"

    inputs = [("Data", Orange.data.Table, "set_data")]
    outputs = [("Network", network.Graph)]

    settingsHandler = settings.DomainContextHandler()

    taxid = settings.Setting("9606")
    gene_var_index = settings.ContextSetting(-1)
    use_attr_names = settings.ContextSetting(False)

    network_source = settings.Setting(1)
    include_neighborhood = settings.Setting(True)
    min_score = settings.Setting(0.9)

    want_main_area = False

    def __init__(self, parent=None):
        super().__init__(parent)

        self.taxids = taxonomy.common_taxids()
        self.current_taxid_index = self.taxids.index(self.taxid)

        self.data = None
        self.geneinfo = None
        self.nettask = None
        self._invalidated = False

        box = gui.widgetBox(self.controlArea, "Info")
        self.info = gui.widgetLabel(box, "No data on input\n")

        box = gui.widgetBox(self.controlArea, "Organism")
        self.organism_cb = gui.comboBox(
            box, self, "current_taxid_index",
            items=map(taxonomy.name, self.taxids),
            callback=self._update_organism
        )
        box = gui.widgetBox(self.controlArea, "Genes")
        self.genes_cb = gui.comboBox(
            box, self, "gene_var_index", callback=self._update_query_genes
        )
        self.varmodel = itemmodels.VariableListModel()
        self.genes_cb.setModel(self.varmodel)

        gui.checkBox(
            box, self, "use_attr_names",
            "Use attribute names",
            callback=self._update_query_genes
        )

        box = gui.widgetBox(self.controlArea, "Network")
        gui.comboBox(
            box, self, "network_source",
            items=[s.name for s in SOURCES],
            callback=self._on_source_db_changed
        )
        gui.checkBox(
            box, self, "include_neighborhood",
            "Include immediate gene neighbors",
            callback=self.invalidate
        )
        self.score_spin = gui.doubleSpin(
            box, self, "min_score", 0.0, 1.0, step=0.001,
            label="Minimal edge score",
            callback=self.invalidate
        )
        self.score_spin.setEnabled(SOURCES[self.network_source].score_filter)

        box = gui.widgetBox(self.controlArea, "Commit")
        gui.button(box, self, "Retrieve", callback=self.commit, default=True)

        self.setSizePolicy(QtGui.QSizePolicy.Fixed, QtGui.QSizePolicy.Fixed)
        self.layout().setSizeConstraint(QtGui.QLayout.SetFixedSize)

        self.executor = ThreadExecutor()

    def set_data(self, data):
        self.closeContext()
        self.data = data
        if data is not None:
            self.varmodel[:] = string_variables(data.domain)
            taxid = data_hints.get_hint(data, "taxid", default=self.taxid)

            if taxid in self.taxids:
                self.set_organism(self.taxids.index(taxid))

            self.use_attr_names = data_hints.get_hint(
                data, "genesinrows", default=self.use_attr_names
            )

            if not (0 <= self.gene_var_index < len(self.varmodel)):
                self.gene_var_index = len(self.varmodel) - 1

            self.openContext(data)
            self.invalidate()
            self.commit()
        else:
            self.varmodel[:] = []
            self.send("Network", None)

    def set_source_db(self, dbindex):
        self.network_source = dbindex
        self.invalidate()

    def set_organism(self, index):
        self.current_taxid_index = index
        self.taxid = self.taxids[index]
        self.invalidate()

    def set_gene_var(self, index):
        self.gene_var_index = index
        self.invalidate()

    def query_genes(self):
        if self.use_attr_names:
            if self.data is not None:
                return [var.name for var in self.data.domain.attributes]
            else:
                return []
        elif self.gene_var_index >= 0:
            var = self.varmodel[self.gene_var_index]
            genes = [str(inst[var]) for inst in self.data
                     if not compat.isunknown(inst[var])]
            return list(unique(genes))
        else:
            return []

    def invalidate(self):
        self._invalidated = True

        if self.nettask is not None:
            self.nettask.finished.disconnect(self._on_result_ready)
            self.nettask.future().cancel()
            self.nettask = None

    @Slot()
    def advance(self):
        self.progressBarValue = (self.progressBarValue + 1) % 100

    @Slot(float)
    def set_progress(self, value):
        self.progressBarSet(value, processEvents=None)

    def commit(self):
        include_neighborhood = self.include_neighborhood
        query_genes = self.query_genes()
        source = SOURCES[self.network_source]
        if source.score_filter:
            min_score = self.min_score
            assert source.name == "STRING"
            min_score = min_score * 1000
        else:
            min_score = None

        taxid = self.taxid
        progress = methodinvoke(self, "advance")
        if self.geneinfo is None:
            self.geneinfo = self.executor.submit(
                fetch_ncbi_geneinfo, taxid, progress
            )

        geneinfo_f = self.geneinfo
        taxmap = source.tax_mapping
        db_taxid = taxmap.get(taxid, taxid)

        if db_taxid is None:
            raise ValueError("invalid taxid for this network")

        def fetch_network():
            geneinfo = geneinfo_f.result()
            ppidb = fetch_ppidb(source, db_taxid, progress)
            return get_gene_network(ppidb, geneinfo, db_taxid, query_genes,
                                    include_neighborhood=include_neighborhood,
                                    min_score=min_score,
                                    progress=methodinvoke(self, "set_progress", (float,)))

        self.nettask = Task(function=fetch_network)
        self.nettask.finished.connect(self._on_result_ready)

        self.executor.submit(self.nettask)

        self.setBlocking(True)
        self.setEnabled(False)
        self.progressBarInit()
        self._invalidated = False
        self._update_info()

    @Slot(object)
    def _on_result_ready(self,):
        self.progressBarFinished()
        self.setBlocking(False)
        self.setEnabled(True)
        net = self.nettask.result()
        self._update_info()
        self.send("Network", net)

    def _on_source_db_changed(self):
        source = SOURCES[self.network_source]
        self.score_spin.setEnabled(source.score_filter)
        self.invalidate()

    def _update_organism(self):
        self.taxid = self.taxids[self.current_taxid_index]
        if self.geneinfo is not None:
            self.geneinfo.cancel()
        self.geneinfo = None
        self.invalidate()

    def _update_query_genes(self):
        self.invalidate()

    def _update_info(self):
        if self.data is None:
            self.info.setText("No data on input\n")
        else:
            names = self.query_genes()
            lines = ["%i unique genes on input" % len(set(names))]
            if self.nettask is not None:
                if not self.nettask.future().done():
                    lines.append("Retrieving ...")
                else:
                    net = self.nettask.result()
                    lines.append("%i nodes %i edges" %
                                 (len(net.nodes()), len(net.edges())))
            else:
                lines.append("")

            self.info.setText("\n".join(lines))
    def __init__(self, parent=None, signalManager=None,
                 name="Databases update"):
        OWWidget.__init__(self, parent, signalManager, name,
                          wantMainArea=False)

        self.searchString = ""

        fbox = gui.widgetBox(self.controlArea, "Filter")
        self.completer = TokenListCompleter(
            self, caseSensitivity=Qt.CaseInsensitive)
        self.lineEditFilter = QLineEdit(textChanged=self.SearchUpdate)
        self.lineEditFilter.setCompleter(self.completer)

        fbox.layout().addWidget(self.lineEditFilter)

        box = gui.widgetBox(self.controlArea, "Files")

        self.filesView = QTreeWidget(self)
        self.filesView.setHeaderLabels(
            ["", "Data Source", "Update", "Last Updated", "Size"])

        self.filesView.setRootIsDecorated(False)
        self.filesView.setUniformRowHeights(True)
        self.filesView.setSelectionMode(QAbstractItemView.NoSelection)
        self.filesView.setSortingEnabled(True)
        self.filesView.sortItems(1, Qt.AscendingOrder)
        self.filesView.setItemDelegateForColumn(
            0, UpdateOptionsItemDelegate(self.filesView))

        self.filesView.model().layoutChanged.connect(self.SearchUpdate)

        box.layout().addWidget(self.filesView)

        box = gui.widgetBox(self.controlArea, orientation="horizontal")
        self.updateButton = gui.button(
            box, self, "Update all",
            callback=self.UpdateAll,
            tooltip="Update all updatable files",
         )

        self.downloadButton = gui.button(
            box, self, "Download all",
            callback=self.DownloadFiltered,
            tooltip="Download all filtered files shown"
        )

        self.cancelButton = gui.button(
            box, self, "Cancel", callback=self.Cancel,
            tooltip="Cancel scheduled downloads/updates."
        )

        self.retryButton = gui.button(
            box, self, "Reconnect", callback=self.RetrieveFilesList
        )
        self.retryButton.hide()

        gui.rubber(box)
        self.warning(0)

        box = gui.widgetBox(self.controlArea, orientation="horizontal")
        gui.rubber(box)

        self.infoLabel = QLabel()
        self.infoLabel.setAlignment(Qt.AlignCenter)

        self.controlArea.layout().addWidget(self.infoLabel)
        self.infoLabel.setSizePolicy(QSizePolicy.Expanding, QSizePolicy.Fixed)

        self.updateItems = []

        self.resize(800, 600)

        self.progress = ProgressState(self, maximum=3)
        self.progress.valueChanged.connect(self._updateProgress)
        self.progress.rangeChanged.connect(self._updateProgress)
        self.executor = ThreadExecutor(
            threadPool=QThreadPool(maxThreadCount=2)
        )

        task = Task(self, function=self.RetrieveFilesList)
        task.exceptionReady.connect(self.HandleError)
        task.start()

        self._tasks = []
        self._haveProgress = False
예제 #14
0
class OWGeneNetwork(widget.OWWidget):
    name = "Gene Network"
    description = "Extract a gene network for a set of genes."
    icon = "../widgets/icons/GeneNetwork.svg"

    inputs = [("Data", Orange.data.Table, "set_data")]
    outputs = [("Network", network.Graph)]

    settingsHandler = settings.DomainContextHandler()

    taxid = settings.Setting("9606")
    gene_var_index = settings.ContextSetting(-1)
    use_attr_names = settings.ContextSetting(False)

    network_source = settings.Setting(1)
    include_neighborhood = settings.Setting(True)
    min_score = settings.Setting(0.9)

    want_main_area = False

    def __init__(self, parent=None):
        super().__init__(parent)

        self.taxids = taxonomy.common_taxids()
        self.current_taxid_index = self.taxids.index(self.taxid)

        self.data = None
        self.geneinfo = None
        self.nettask = None
        self._invalidated = False

        box = gui.widgetBox(self.controlArea, "Info")
        self.info = gui.widgetLabel(box, "No data on input\n")

        box = gui.widgetBox(self.controlArea, "Organism")
        self.organism_cb = gui.comboBox(box,
                                        self,
                                        "current_taxid_index",
                                        items=map(taxonomy.name, self.taxids),
                                        callback=self._update_organism)
        box = gui.widgetBox(self.controlArea, "Genes")
        self.genes_cb = gui.comboBox(box,
                                     self,
                                     "gene_var_index",
                                     callback=self._update_query_genes)
        self.varmodel = itemmodels.VariableListModel()
        self.genes_cb.setModel(self.varmodel)

        gui.checkBox(box,
                     self,
                     "use_attr_names",
                     "Use attribute names",
                     callback=self._update_query_genes)

        box = gui.widgetBox(self.controlArea, "Network")
        gui.comboBox(box,
                     self,
                     "network_source",
                     items=[s.name for s in SOURCES],
                     callback=self._on_source_db_changed)
        gui.checkBox(box,
                     self,
                     "include_neighborhood",
                     "Include immediate gene neighbors",
                     callback=self.invalidate)
        self.score_spin = gui.doubleSpin(box,
                                         self,
                                         "min_score",
                                         0.0,
                                         1.0,
                                         step=0.001,
                                         label="Minimal edge score",
                                         callback=self.invalidate)
        self.score_spin.setEnabled(SOURCES[self.network_source].score_filter)

        box = gui.widgetBox(self.controlArea, "Commit")
        gui.button(box, self, "Retrieve", callback=self.commit, default=True)

        self.setSizePolicy(QSizePolicy.Fixed, QSizePolicy.Fixed)
        self.layout().setSizeConstraint(QLayout.SetFixedSize)

        self.executor = ThreadExecutor()

    def set_data(self, data):
        self.closeContext()
        self.data = data
        if data is not None:
            self.varmodel[:] = string_variables(data.domain)
            taxid = data_hints.get_hint(data, "taxid", default=self.taxid)

            if taxid in self.taxids:
                self.set_organism(self.taxids.index(taxid))

            self.use_attr_names = data_hints.get_hint(
                data, "genesinrows", default=self.use_attr_names)

            if not (0 <= self.gene_var_index < len(self.varmodel)):
                self.gene_var_index = len(self.varmodel) - 1

            self.openContext(data)
            self.invalidate()
            self.commit()
        else:
            self.varmodel[:] = []
            self.send("Network", None)

    def set_source_db(self, dbindex):
        self.network_source = dbindex
        self.invalidate()

    def set_organism(self, index):
        self.current_taxid_index = index
        self.taxid = self.taxids[index]
        self.invalidate()

    def set_gene_var(self, index):
        self.gene_var_index = index
        self.invalidate()

    def query_genes(self):
        if self.use_attr_names:
            if self.data is not None:
                return [var.name for var in self.data.domain.attributes]
            else:
                return []
        elif self.gene_var_index >= 0:
            var = self.varmodel[self.gene_var_index]
            genes = [
                str(inst[var]) for inst in self.data
                if not compat.isunknown(inst[var])
            ]
            return list(unique(genes))
        else:
            return []

    def invalidate(self):
        self._invalidated = True

        if self.nettask is not None:
            self.nettask.finished.disconnect(self._on_result_ready)
            self.nettask.future().cancel()
            self.nettask = None

    @Slot()
    def advance(self):
        self.progressBarValue = (self.progressBarValue + 1) % 100

    @Slot(float)
    def set_progress(self, value):
        self.progressBarSet(value, processEvents=None)

    def commit(self):
        include_neighborhood = self.include_neighborhood
        query_genes = self.query_genes()
        source = SOURCES[self.network_source]
        if source.score_filter:
            min_score = self.min_score
            assert source.name == "STRING"
            min_score = min_score * 1000
        else:
            min_score = None

        taxid = self.taxid
        progress = methodinvoke(self, "advance")
        if self.geneinfo is None:
            self.geneinfo = self.executor.submit(fetch_ncbi_geneinfo, taxid,
                                                 progress)

        geneinfo_f = self.geneinfo
        taxmap = source.tax_mapping
        db_taxid = taxmap.get(taxid, taxid)

        if db_taxid is None:
            raise ValueError("invalid taxid for this network")

        def fetch_network():
            geneinfo = geneinfo_f.result()
            ppidb = fetch_ppidb(source, db_taxid, progress)
            return get_gene_network(ppidb,
                                    geneinfo,
                                    db_taxid,
                                    query_genes,
                                    include_neighborhood=include_neighborhood,
                                    min_score=min_score,
                                    progress=methodinvoke(
                                        self, "set_progress", (float, )))

        self.nettask = Task(function=fetch_network)
        self.nettask.finished.connect(self._on_result_ready)

        self.executor.submit(self.nettask)

        self.setBlocking(True)
        self.setEnabled(False)
        self.progressBarInit()
        self._invalidated = False
        self._update_info()

    @Slot()
    def _on_result_ready(self, ):
        self.progressBarFinished()
        self.setBlocking(False)
        self.setEnabled(True)
        net = self.nettask.result()
        self._update_info()
        self.send("Network", net)

    def _on_source_db_changed(self):
        source = SOURCES[self.network_source]
        self.score_spin.setEnabled(source.score_filter)
        self.invalidate()

    def _update_organism(self):
        self.taxid = self.taxids[self.current_taxid_index]
        if self.geneinfo is not None:
            self.geneinfo.cancel()
        self.geneinfo = None
        self.invalidate()

    def _update_query_genes(self):
        self.invalidate()

    def _update_info(self):
        if self.data is None:
            self.info.setText("No data on input\n")
        else:
            names = self.query_genes()
            lines = ["%i unique genes on input" % len(set(names))]
            if self.nettask is not None:
                if not self.nettask.future().done():
                    lines.append("Retrieving ...")
                else:
                    net = self.nettask.result()
                    lines.append("%i nodes %i edges" %
                                 (len(net.nodes()), len(net.edges())))
            else:
                lines.append("")

            self.info.setText("\n".join(lines))
예제 #15
0
    def updateAnnotations(self):
        if self.data is None:
            return

        assert not self.__state & OWSetEnrichment.Initializing
        self._cancelPending()
        self._clearView()

        self.information(0)
        self.warning(0)
        self.error(0)

        if not self.genesinrows and len(self.geneAttrs) == 0:
            self.error(0, "Input data contains no columns with gene names")
            return

        self.__state = OWSetEnrichment.RunningEnrichment

        taxid = self.taxid_list[self.speciesIndex]
        self.taxid = taxid

        categories = self.selectedCategories()

        clusterGenes = self.genesFromTable(self.data)

        if self.referenceData is not None and self.useReferenceData:
            referenceGenes = self.genesFromTable(self.referenceData)
        else:
            referenceGenes = None

        self.currentAnnotatedCategories = categories

        genematcher = self._genematcher()

        self.progressBarInit()

        ## Load collections in a worker thread
        # TODO: Use cached collections if already loaded and
        # use ensure_genesetsdownloaded with progress report (OWSelectGenes)
        collections = self._executor.submit(geneset.collections, *categories)

        def refset_null():
            """Return the default background reference set"""
            col = collections.result()
            return reduce(operator.ior, (set(g.genes) for g in col), set())

        def refset_ncbi():
            """Return all NCBI gene names"""
            geneinfo = gene.NCBIGeneInfo(taxid)
            return set(geneinfo.keys())

        def namematcher():
            matcher = genematcher.result()
            match = matcher.set_targets(ref_set.result())
            match.umatch = memoize(match.umatch)
            return match

        def map_unames():
            matcher = namematcher.result()
            query = list(filter(None, map(matcher.umatch, querynames)))
            reference = list(
                filter(None, map(matcher.umatch, ref_set.result())))
            return query, reference

        if self._nogenematching():
            if referenceGenes is None:
                ref_set = self._executor.submit(refset_null)
            else:
                ref_set = fulfill(referenceGenes)
        else:
            if referenceGenes == None:
                ref_set = self._executor.submit(refset_ncbi)
            else:
                ref_set = fulfill(referenceGenes)

        namematcher = self._executor.submit(namematcher)
        querynames = clusterGenes

        state = types.SimpleNamespace()
        state.query_set = clusterGenes
        state.reference_set = referenceGenes
        state.namematcher = namematcher
        state.query_count = len(set(clusterGenes))
        state.reference_count = (len(set(referenceGenes))
                                 if referenceGenes is not None else None)

        state.cancelled = False

        progress = methodinvoke(self, "_setProgress", (float, ))
        info = methodinvoke(self, "_setRunInfo", (str, ))

        @withtraceback
        def run():
            info("Loading data")
            match = namematcher.result()
            query, reference = map_unames()
            gscollections = collections.result()

            results = []
            info("Running enrichment")
            p = 0
            for i, gset in enumerate(gscollections):
                genes = set(filter(None, map(match.umatch, gset.genes)))
                enr = set_enrichment(genes, reference, query)
                results.append((gset, enr))

                if state.cancelled:
                    raise UserInteruptException

                pnew = int(100 * i / len(gscollections))
                if pnew != p:
                    progress(pnew)
                    p = pnew
            progress(100)
            info("")
            return query, reference, results

        task = Task(function=run)
        task.resultReady.connect(self.__on_enrichment_finished)
        task.exceptionReady.connect(self.__on_enrichment_failed)
        result = self._executor.submit(task)
        state.results = result

        self.state = state
        self._updatesummary()
예제 #16
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    def test_task(self):
        results = []

        task = Task(function=QThread.currentThread)
        task.resultReady.connect(results.append)

        task.start()
        self.app.processEvents()

        self.assertSequenceEqual(results, [QThread.currentThread()])

        thread = QThread()
        thread.start()
        try:
            task = Task(function=QThread.currentThread)
            task.moveToThread(thread)

            self.assertIsNot(task.thread(), QThread.currentThread())
            self.assertIs(task.thread(), thread)
            results = Future()

            def record(value):
                # record the result value and the calling thread
                results.set_result((QThread.currentThread(), value))

            task.resultReady.connect(record, Qt.DirectConnection)
            task.start()
            f = task.future()
            emit_thread, thread_ = results.result(3)
            self.assertIs(f.result(3), thread)
            self.assertIs(emit_thread, thread)
            self.assertIs(thread_, thread)
        finally:
            thread.quit()
            thread.wait()
예제 #17
0
class OWGEODatasets(OWWidget):
    name = "GEO Data Sets"
    description = "Access to Gene Expression Omnibus data sets."
    icon = "icons/OWGEODatasets.svg"
    priority = 2

    inputs = []
    outputs = [("Expression Data", Table)]

    settingsList = [
        "outputRows", "mergeSpots", "gdsSelectionStates", "splitterSettings",
        "currentGds", "autoCommit", "datasetNames"
    ]

    outputRows = Setting(True)
    mergeSpots = Setting(True)
    gdsSelectionStates = Setting({})
    currentGds = Setting(None)
    datasetNames = Setting({})
    splitterSettings = Setting((
        b'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xea\x00\x00\x00\xd7\x01\x00\x00\x00\x07\x01\x00\x00\x00\x02',
        b'\x00\x00\x00\xff\x00\x00\x00\x00\x00\x00\x00\x02\x00\x00\x01\xb5\x00\x00\x02\x10\x01\x00\x00\x00\x07\x01\x00\x00\x00\x01'
    ))

    autoCommit = Setting(False)

    def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
        OWWidget.__init__(self, parent, signalManager, name)

        self.selectionChanged = False
        self.filterString = ""
        self.datasetName = ""

        ## GUI
        box = gui.widgetBox(self.controlArea, "Info", addSpace=True)
        self.infoBox = gui.widgetLabel(box, "Initializing\n\n")

        box = gui.widgetBox(self.controlArea, "Output", addSpace=True)
        gui.radioButtonsInBox(box,
                              self,
                              "outputRows",
                              ["Genes in rows", "Samples in rows"],
                              "Rows",
                              callback=self.commitIf)

        gui.checkBox(box,
                     self,
                     "mergeSpots",
                     "Merge spots of same gene",
                     callback=self.commitIf)

        gui.separator(box)
        self.nameEdit = gui.lineEdit(
            box,
            self,
            "datasetName",
            "Data set name",
            tooltip="Override the default output data set name",
            callback=self.onNameEdited)
        self.nameEdit.setPlaceholderText("")

        if sys.version_info < (3, ):
            box = gui.widgetBox(self.controlArea, "Commit", addSpace=True)
            self.commitButton = gui.button(box,
                                           self,
                                           "Commit",
                                           callback=self.commit)
            cb = gui.checkBox(box, self, "autoCommit", "Commit on any change")
            gui.setStopper(self, self.commitButton, cb, "selectionChanged",
                           self.commit)
        else:
            gui.auto_commit(self.controlArea,
                            self,
                            "autoCommit",
                            "Commit",
                            box="Commit")
            self.commitIf = self.commit

        gui.rubber(self.controlArea)

        gui.widgetLabel(self.mainArea, "Filter")
        self.filterLineEdit = QLineEdit(textChanged=self.filter)
        self.completer = TokenListCompleter(self,
                                            caseSensitivity=Qt.CaseInsensitive)
        self.filterLineEdit.setCompleter(self.completer)

        self.mainArea.layout().addWidget(self.filterLineEdit)

        splitter = QSplitter(Qt.Vertical, self.mainArea)
        self.mainArea.layout().addWidget(splitter)
        self.treeWidget = QTreeView(splitter)

        self.treeWidget.setSelectionMode(QTreeView.SingleSelection)
        self.treeWidget.setRootIsDecorated(False)
        self.treeWidget.setSortingEnabled(True)
        self.treeWidget.setAlternatingRowColors(True)
        self.treeWidget.setUniformRowHeights(True)
        self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)

        linkdelegate = gui.LinkStyledItemDelegate(self.treeWidget)
        self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
        self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
        self.treeWidget.setItemDelegateForColumn(
            0, gui.IndicatorItemDelegate(self.treeWidget, role=Qt.DisplayRole))

        proxyModel = MySortFilterProxyModel(self.treeWidget)
        self.treeWidget.setModel(proxyModel)
        self.treeWidget.selectionModel().selectionChanged.connect(
            self.updateSelection)
        self.treeWidget.viewport().setMouseTracking(True)

        splitterH = QSplitter(Qt.Horizontal, splitter)

        box = gui.widgetBox(splitterH, "Description")
        self.infoGDS = gui.widgetLabel(box, "")
        self.infoGDS.setWordWrap(True)
        gui.rubber(box)

        box = gui.widgetBox(splitterH, "Sample Annotations")
        self.annotationsTree = QTreeWidget(box)
        self.annotationsTree.setHeaderLabels(
            ["Type (Sample annotations)", "Sample count"])
        self.annotationsTree.setRootIsDecorated(True)
        box.layout().addWidget(self.annotationsTree)
        self.annotationsTree.itemChanged.connect(
            self.annotationSelectionChanged)
        self._annotationsUpdating = False
        self.splitters = splitter, splitterH

        for sp, setting in zip(self.splitters, self.splitterSettings):
            sp.splitterMoved.connect(self.splitterMoved)
            sp.restoreState(setting)

        self.searchKeys = [
            "dataset_id", "title", "platform_organism", "description"
        ]

        self.gds = []
        self.gds_info = None

        self.resize(1000, 600)

        self.setBlocking(True)
        self.setEnabled(False)
        self.progressBarInit()

        self._executor = ThreadExecutor()

        func = partial(get_gds_model,
                       methodinvoke(self, "_setProgress", (float, )))
        self._inittask = Task(function=func)
        self._inittask.finished.connect(self._initializemodel)
        self._executor.submit(self._inittask)

        self._datatask = None

    @Slot(float)
    def _setProgress(self, value):
        self.progressBarValue = value

    def _initializemodel(self):
        assert self.thread() is QThread.currentThread()
        model, self.gds_info, self.gds = self._inittask.result()
        model.setParent(self)

        proxy = self.treeWidget.model()
        proxy.setFilterKeyColumn(0)
        proxy.setFilterRole(TextFilterRole)
        proxy.setFilterCaseSensitivity(False)
        proxy.setFilterFixedString(self.filterString)

        proxy.setSourceModel(model)
        proxy.sort(0, Qt.DescendingOrder)

        self.progressBarFinished()
        self.setBlocking(False)
        self.setEnabled(True)

        filter_items = " ".join(gds[key] for gds in self.gds
                                for key in self.searchKeys)
        tr_chars = ",.:;!?(){}[]_-+\\|/%#@$^&*<>~`"
        tr_table = str.maketrans(tr_chars, " " * len(tr_chars))
        filter_items = filter_items.translate(tr_table)

        filter_items = sorted(set(filter_items.split(" ")))
        filter_items = [item for item in filter_items if len(item) > 3]

        self.completer.setTokenList(filter_items)

        if self.currentGds:
            current_id = self.currentGds["dataset_id"]
            gdss = [(i, proxy.data(proxy.index(i, 1), Qt.DisplayRole))
                    for i in range(proxy.rowCount())]
            current = [i for i, data in gdss if data and data == current_id]
            if current:
                current_index = proxy.index(current[0], 0)
                self.treeWidget.selectionModel().select(
                    current_index,
                    QItemSelectionModel.Select | QItemSelectionModel.Rows)
                self.treeWidget.scrollTo(current_index,
                                         QTreeView.PositionAtCenter)

        for i in range(8):
            self.treeWidget.resizeColumnToContents(i)

        self.treeWidget.setColumnWidth(
            1, min(self.treeWidget.columnWidth(1), 300))
        self.treeWidget.setColumnWidth(
            2, min(self.treeWidget.columnWidth(2), 200))

        self.updateInfo()

    def updateInfo(self):
        gds_info = self.gds_info
        text = ("%i datasets\n%i datasets cached\n" %
                (len(gds_info),
                 len(glob.glob(serverfiles.localpath("GEO") + "/GDS*"))))
        filtered = self.treeWidget.model().rowCount()
        if len(self.gds) != filtered:
            text += ("%i after filtering") % filtered
        self.infoBox.setText(text)

    def updateSelection(self, *args):
        current = self.treeWidget.selectedIndexes()
        mapToSource = self.treeWidget.model().mapToSource
        current = [mapToSource(index).row() for index in current]
        if current:
            self.currentGds = self.gds[current[0]]
            self.setAnnotations(self.currentGds)
            self.infoGDS.setText(self.currentGds.get("description", ""))
            self.nameEdit.setPlaceholderText(self.currentGds["title"])
            self.datasetName = \
                self.datasetNames.get(self.currentGds["dataset_id"], "")
        else:
            self.currentGds = None
            self.nameEdit.setPlaceholderText("")
            self.datasetName = ""

        self.commitIf()

    def setAnnotations(self, gds):
        self._annotationsUpdating = True
        self.annotationsTree.clear()

        annotations = defaultdict(set)
        subsetscount = {}
        for desc in gds["subsets"]:
            annotations[desc["type"]].add(desc["description"])
            subsetscount[desc["description"]] = str(len(desc["sample_id"]))

        for type, subsets in annotations.items():
            key = (gds["dataset_id"], type)
            subsetItem = QTreeWidgetItem(self.annotationsTree, [type])
            subsetItem.setFlags(subsetItem.flags() | Qt.ItemIsUserCheckable
                                | Qt.ItemIsTristate)
            subsetItem.setCheckState(
                0, self.gdsSelectionStates.get(key, Qt.Checked))
            subsetItem.key = key
            for subset in subsets:
                key = (gds["dataset_id"], type, subset)
                item = QTreeWidgetItem(
                    subsetItem, [subset, subsetscount.get(subset, "")])
                item.setFlags(item.flags() | Qt.ItemIsUserCheckable)
                item.setCheckState(
                    0, self.gdsSelectionStates.get(key, Qt.Checked))
                item.key = key
        self._annotationsUpdating = False
        self.annotationsTree.expandAll()
        for i in range(self.annotationsTree.columnCount()):
            self.annotationsTree.resizeColumnToContents(i)

    def annotationSelectionChanged(self, item, column):
        if self._annotationsUpdating:
            return
        for i in range(self.annotationsTree.topLevelItemCount()):
            item = self.annotationsTree.topLevelItem(i)
            self.gdsSelectionStates[item.key] = item.checkState(0)
            for j in range(item.childCount()):
                child = item.child(j)
                self.gdsSelectionStates[child.key] = child.checkState(0)

    def filter(self):
        filter_string = self.filterLineEdit.text()
        proxyModel = self.treeWidget.model()
        if proxyModel:
            strings = filter_string.lower().strip().split()
            proxyModel.setFilterFixedStrings(strings)
            self.updateInfo()

    def selectedSamples(self):
        """
        Return the currently selected sample annotations.

        The return value is a list of selected (sample type, sample value)
        tuples.

        .. note:: if some Sample annotation type has no selected values.
                  this method will return all values for it.

        """
        samples = []
        unused_types = []
        used_types = []
        for stype in childiter(self.annotationsTree.invisibleRootItem()):
            selected_values = []
            all_values = []
            for sval in childiter(stype):
                value = (str(stype.text(0)), str(sval.text(0)))
                if self.gdsSelectionStates.get(sval.key, True):
                    selected_values.append(value)
                all_values.append(value)
            if selected_values:
                samples.extend(selected_values)
                used_types.append(str(stype.text(0)))
            else:
                # If no sample of sample type is selected we don't filter
                # on it.
                samples.extend(all_values)
                unused_types.append(str(stype.text(0)))

        return samples, used_types

    def commitIf(self):
        if self.autoCommit:
            self.commit()
        else:
            self.selectionChanged = True

    @Slot(int, int)
    def progressCompleted(self, value, total):
        if total > 0:
            self.progressBarSet(100. * value / total, processEvents=False)
        else:
            pass
            # TODO: report 'indeterminate progress'

    def commit(self):
        if self.currentGds:
            self.error(0)
            sample_type = None
            self.progressBarInit(processEvents=None)

            _, groups = self.selectedSamples()
            if len(groups) == 1 and self.outputRows:
                sample_type = groups[0]

            self.setEnabled(False)
            self.setBlocking(True)

            progress = methodinvoke(self, "progressCompleted", (int, int))

            def get_data(gds_id, report_genes, transpose, sample_type, title):
                gds_ensure_downloaded(gds_id, progress)
                gds = GDS(gds_id)
                data = gds.get_data(report_genes=report_genes,
                                    transpose=transpose,
                                    sample_type=sample_type)
                data.name = title
                return data

            get_data = partial(get_data,
                               self.currentGds["dataset_id"],
                               report_genes=self.mergeSpots,
                               transpose=self.outputRows,
                               sample_type=sample_type,
                               title=self.datasetName
                               or self.currentGds["title"])
            self._datatask = Task(function=get_data)
            self._datatask.finished.connect(self._on_dataready)
            self._executor.submit(self._datatask)

    def _on_dataready(self):
        self.setEnabled(True)
        self.setBlocking(False)
        self.progressBarFinished(processEvents=False)

        try:
            data = self._datatask.result()
        except urlrequest.URLError as error:
            self.error(0, ("Error while connecting to the NCBI ftp server! "
                           "'%s'" % error))
            sys.excepthook(type(error), error, getattr(error, "__traceback__"))
            return
        finally:
            self._datatask = None

        data_name = data.name
        samples, _ = self.selectedSamples()

        self.warning(0)
        message = None
        if self.outputRows:

            def samplesinst(ex):
                out = []
                for meta in data.domain.metas:
                    out.append((meta.name, ex[meta].value))

                if data.domain.class_var.name != 'class':
                    out.append((data.domain.class_var.name,
                                ex[data.domain.class_var].value))

                return out

            samples = set(samples)
            mask = [samples.issuperset(samplesinst(ex)) for ex in data]
            data = data[numpy.array(mask, dtype=bool)]
            if len(data) == 0:
                message = "No samples with selected sample annotations."
        else:
            samples = set(samples)
            domain = Domain([
                attr for attr in data.domain.attributes
                if samples.issuperset(attr.attributes.items())
            ], data.domain.class_var, data.domain.metas)
            #             domain.addmetas(data.domain.getmetas())

            if len(domain.attributes) == 0:
                message = "No samples with selected sample annotations."
            stypes = set(s[0] for s in samples)
            for attr in domain.attributes:
                attr.attributes = dict(
                    (key, value) for key, value in attr.attributes.items()
                    if key in stypes)
            data = Table(domain, data)

        if message is not None:
            self.warning(0, message)

        data_hints.set_hint(data, TAX_ID, self.currentGds.get("taxid", ""))
        data_hints.set_hint(data, GENE_NAME, bool(self.outputRows))

        data.name = data_name
        self.send("Expression Data", data)

        model = self.treeWidget.model().sourceModel()
        row = self.gds.index(self.currentGds)

        model.setData(model.index(row, 0), " ", Qt.DisplayRole)

        self.updateInfo()
        self.selectionChanged = False

    def splitterMoved(self, *args):
        self.splitterSettings = [
            bytes(sp.saveState()) for sp in self.splitters
        ]

    def send_report(self):
        self.report_items("GEO Dataset",
                          [("ID", self.currentGds['dataset_id']),
                           ("Title", self.currentGds['title']),
                           ("Organism", self.currentGds['sample_organism'])])
        self.report_items("Data",
                          [("Samples", self.currentGds['sample_count']),
                           ("Features", self.currentGds['feature_count']),
                           ("Genes", self.currentGds['gene_count'])])
        self.report_name("Sample annotations")
        subsets = defaultdict(list)
        for subset in self.currentGds['subsets']:
            subsets[subset['type']].append(
                (subset['description'], len(subset['sample_id'])))
        self.report_html += "<ul>"
        for type in subsets:
            self.report_html += "<b>" + type + ":</b></br>"
            for desc, count in subsets[type]:
                self.report_html += 9 * "&nbsp" + "<b>{}:</b> {}</br>".format(
                    desc, count)
        self.report_html += "</ul>"

    def onDeleteWidget(self):
        if self._inittask:
            self._inittask.future().cancel()
            self._inittask.finished.disconnect(self._initializemodel)
        if self._datatask:
            self._datatask.future().cancel()
            self._datatask.finished.disconnect(self._on_dataready)
        self._executor.shutdown(wait=False)

        super(OWGEODatasets, self).onDeleteWidget()

    def onNameEdited(self):
        if self.currentGds:
            gds_id = self.currentGds["dataset_id"]
            self.datasetNames[gds_id] = self.nameEdit.text()
            self.commitIf()
예제 #18
0
    def __init__(self, parent=None, signalManager=None, name=" GEO Data Sets"):
        OWWidget.__init__(self, parent, signalManager, name)

        self.selectionChanged = False
        self.filterString = ""
        self.datasetName = ""

        ## GUI
        box = gui.widgetBox(self.controlArea, "Info", addSpace=True)
        self.infoBox = gui.widgetLabel(box, "Initializing\n\n")

        box = gui.widgetBox(self.controlArea, "Output", addSpace=True)
        gui.radioButtonsInBox(box,
                              self,
                              "outputRows",
                              ["Genes in rows", "Samples in rows"],
                              "Rows",
                              callback=self.commitIf)

        gui.checkBox(box,
                     self,
                     "mergeSpots",
                     "Merge spots of same gene",
                     callback=self.commitIf)

        gui.separator(box)
        self.nameEdit = gui.lineEdit(
            box,
            self,
            "datasetName",
            "Data set name",
            tooltip="Override the default output data set name",
            callback=self.onNameEdited)
        self.nameEdit.setPlaceholderText("")

        if sys.version_info < (3, ):
            box = gui.widgetBox(self.controlArea, "Commit", addSpace=True)
            self.commitButton = gui.button(box,
                                           self,
                                           "Commit",
                                           callback=self.commit)
            cb = gui.checkBox(box, self, "autoCommit", "Commit on any change")
            gui.setStopper(self, self.commitButton, cb, "selectionChanged",
                           self.commit)
        else:
            gui.auto_commit(self.controlArea,
                            self,
                            "autoCommit",
                            "Commit",
                            box="Commit")
            self.commitIf = self.commit

        gui.rubber(self.controlArea)

        gui.widgetLabel(self.mainArea, "Filter")
        self.filterLineEdit = QLineEdit(textChanged=self.filter)
        self.completer = TokenListCompleter(self,
                                            caseSensitivity=Qt.CaseInsensitive)
        self.filterLineEdit.setCompleter(self.completer)

        self.mainArea.layout().addWidget(self.filterLineEdit)

        splitter = QSplitter(Qt.Vertical, self.mainArea)
        self.mainArea.layout().addWidget(splitter)
        self.treeWidget = QTreeView(splitter)

        self.treeWidget.setSelectionMode(QTreeView.SingleSelection)
        self.treeWidget.setRootIsDecorated(False)
        self.treeWidget.setSortingEnabled(True)
        self.treeWidget.setAlternatingRowColors(True)
        self.treeWidget.setUniformRowHeights(True)
        self.treeWidget.setEditTriggers(QTreeView.NoEditTriggers)

        linkdelegate = gui.LinkStyledItemDelegate(self.treeWidget)
        self.treeWidget.setItemDelegateForColumn(1, linkdelegate)
        self.treeWidget.setItemDelegateForColumn(8, linkdelegate)
        self.treeWidget.setItemDelegateForColumn(
            0, gui.IndicatorItemDelegate(self.treeWidget, role=Qt.DisplayRole))

        proxyModel = MySortFilterProxyModel(self.treeWidget)
        self.treeWidget.setModel(proxyModel)
        self.treeWidget.selectionModel().selectionChanged.connect(
            self.updateSelection)
        self.treeWidget.viewport().setMouseTracking(True)

        splitterH = QSplitter(Qt.Horizontal, splitter)

        box = gui.widgetBox(splitterH, "Description")
        self.infoGDS = gui.widgetLabel(box, "")
        self.infoGDS.setWordWrap(True)
        gui.rubber(box)

        box = gui.widgetBox(splitterH, "Sample Annotations")
        self.annotationsTree = QTreeWidget(box)
        self.annotationsTree.setHeaderLabels(
            ["Type (Sample annotations)", "Sample count"])
        self.annotationsTree.setRootIsDecorated(True)
        box.layout().addWidget(self.annotationsTree)
        self.annotationsTree.itemChanged.connect(
            self.annotationSelectionChanged)
        self._annotationsUpdating = False
        self.splitters = splitter, splitterH

        for sp, setting in zip(self.splitters, self.splitterSettings):
            sp.splitterMoved.connect(self.splitterMoved)
            sp.restoreState(setting)

        self.searchKeys = [
            "dataset_id", "title", "platform_organism", "description"
        ]

        self.gds = []
        self.gds_info = None

        self.resize(1000, 600)

        self.setBlocking(True)
        self.setEnabled(False)
        self.progressBarInit()

        self._executor = ThreadExecutor()

        func = partial(get_gds_model,
                       methodinvoke(self, "_setProgress", (float, )))
        self._inittask = Task(function=func)
        self._inittask.finished.connect(self._initializemodel)
        self._executor.submit(self._inittask)

        self._datatask = None