예제 #1
0
def main(graph_name):

    cutting_day = 243  # to separate   training-testing

    Niter = 1000

    G = nx.read_gml(graph_name)

    list_id_weekends_T3 = look_for_T3_weekends(
        G
    )  # T3 doesnt share fellows in the weekend  (but they are the exception)

    all_team = "NO"  # as adopters or not

    dir_real_data = '../Results/'

    dir = "../Results/weight_shifts/infection/"

    delta_end = 3.  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    filename_actual_evol = "../Data/Actual_evolution_adopters_NO_fellows_only_attendings.dat"

    file1 = open(
        filename_actual_evol, 'r'
    )  ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
    list_lines_file = file1.readlines()

    list_actual_evol = []
    for line in list_lines_file:  # [1:]:   # i exclude the first row

        num_adopters = float(line.split("\t")[1])
        list_actual_evol.append(num_adopters)

    list_actual_evol_training = list_actual_evol[:cutting_day]
    #   list_actual_evol_testing=list_actual_evol[(cutting_day-1):]   #i dont use this

    ##################################################################

    #../Results/network_final_schedule_withTeam3/infection/Average_time_evolution_Infection_p0.9_Immune0.5_1000iter_2012.dat

    prob_min = 1.00
    prob_max = 1.0
    delta_prob = 0.1

    prob_Immune_min = 0.0
    prob_Immune_max = 0.0
    delta_prob_Immune = 0.1

    #######
    infect_threshold_min = 1.0  # THIS IS FIXED, BECAUSE DOSE CAN BE DEFINED IN UNITS OF IT!!
    infect_threshold_max = 1.01
    delta_infect_threshold = 0.1
    #######

    # of a single encounter with an infected  (it cant be zero or it doesnt make sense!)
    dose_min = 0.200  #infect_threshold_min
    dose_max = 0.201  #######infect_threshold_min/10.
    delta_dose = 0.1  ##infect_threshold_min/10.

    fixed_param = ""  #FIXED_Pimm0_"    # or ""  # for the Results file that contains the sorted list of best parameters

    print_landscape = "NO"  #YES"  # for the whole exploration

    print_training_evol = "YES"  #  "NO"   # once i know the best fit for the training segment, i run it again to get the curve

    if print_landscape == "YES":
        output_file3 = "../Results/weight_shifts/Landscape_parameters_infection_memory_train_" + fixed_param + "_" + str(
            Niter) + "iter_Att_only_middle_day" + str(cutting_day) + ".dat"
        file3 = open(output_file3, 'wt')

        file3.close()

    list_dist_at_ending_point_fixed_parameters = []
    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one
    dict_filenames_prod_distances = {}

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            infect_threshold = infect_threshold_min

            print "  threshold:", infect_threshold

            dose = dose_min
            while dose <= dose_max:

                print "  dose:", dose

                output_file2 = dir + "Average_time_evolution_Infection_memory_training_p" + str(
                    prob_infection) + "_Immune" + str(
                        prob_Immune) + "_FIXED_threshold" + str(
                            infect_threshold) + "_dose" + str(
                                dose) + "_" + str(Niter) + "iter_day" + str(
                                    cutting_day) + "_Att_only_middle.dat"

                #      I DONT NEED TO WRITE IT, COS I WILL USE THE WHOLE FILE FROM THE WHOLE FIT, WITH THE PARAMETER VALUES THAT THE TESTING-UP-TODAY-125 TELLS ME

                output_file4 = dir + "List_adopters_fellows_descending_frequency_Infection_memory_training_p" + str(
                    prob_infection) + "_Immune" + str(
                        prob_Immune) + "_FIXED_threshold" + str(
                            infect_threshold) + "_dose" + str(
                                dose) + "_" + str(Niter) + "iter_day" + str(
                                    cutting_day) + "_Att_only_middle.dat"

                num_Att_adopters = 0.
                num_F_adopters = 0.
                dict_att_freq_adoption_end = {
                }  # to keep track of what fellow is an adopter at the end (to use along with the real ic)
                dict_fellow_freq_adoption_end = {
                }  # to keep track of what fellow is an adopter at the end (to use along with the real ic)
                for n in G.nodes():
                    doctor = G.node[n]["label"]
                    if G.node[n]['type'] == "F":
                        dict_fellow_freq_adoption_end[doctor] = 0.
                    elif G.node[n]['type'] == "A":
                        dict_att_freq_adoption_end[doctor] = 0.

                list_lists_t_evolutions = []

                list_dist_fixed_parameters = []
                list_dist_abs_at_ending_point_fixed_parameters = []
                list_final_num_infected = []

                for iter in range(Niter):

                    #    print "     iter:",iter

                    ########### set I.C.

                    list_I = []  #list infected doctors

                    for n in G.nodes():
                        G.node[n]["status"] = "S"  # all nodes are Susceptible
                        G.node[n]["infec_value"] = 0.
                        if G.node[n]['type'] == "shift":
                            pass

                        else:
                            if G.node[n]['label'] == "Wunderink" or G.node[n][
                                    "label"] == "Weiss":
                                G.node[n]["status"] = "I"
                                G.node[n][
                                    "infec_value"] = infect_threshold + 1.
                                list_I.append(G.node[n]['label'])

                    list_single_t_evolution = []
                    list_single_t_evolution.append(
                        2.0)  # I always start with TWO infected doctors!!
                    old_num_adopters = 2

                    for n in G.nodes(
                    ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                        if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                          == "F"):
                            if G.node[n]['label'] != "Wunderink" and G.node[n][
                                    "label"] != "Weiss":
                                rand = random.random()
                                if rand < prob_Immune:
                                    G.node[n]["status"] = "Immune"

                    ################# the dynamics starts:

                    shift_length = 5  #i know the first shift (order 0) is of length 5

                    t = 0
                    while t < cutting_day:  # loop over shifts, in order   just until cutting day (training segment)

                        for n in G.nodes():
                            if G.node[n]['type'] == "shift" and G.node[n][
                                    'order'] == t:
                                shift_length = int(G.node[n]['shift_length'])
                                effective_shift_length = shift_length

                                if shift_length == 2 and n not in list_id_weekends_T3:
                                    effective_shift_length = 1  # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)

                                flag_possible_infection = 0
                                for doctor in G.neighbors(
                                        n
                                ):  #first i check if any doctor is infected in this shift
                                    if G.node[doctor]["status"] == "I":
                                        flag_possible_infection = 1

                                if flag_possible_infection:
                                    for doctor in G.neighbors(
                                            n
                                    ):  # then the doctors in that shift, gets infected with prob_infection

                                        for i in range(
                                                effective_shift_length
                                        ):  # i repeat the infection process several times, to acount for shift length
                                            if G.node[doctor]["status"] == "S":
                                                rand = random.random()
                                                if rand < prob_infection:  # with prob p the infection occurres

                                                    G.node[doctor][
                                                        "infec_value"] += dose  # and bumps the infection_value of that susceptible dr

                                                    if G.node[doctor][
                                                            "infec_value"] >= infect_threshold:  # becomes  infected

                                                        G.node[doctor][
                                                            "status"] = "I"

                                                        if G.node[doctor][
                                                                "type"] == "A":  # fellows participate in the dynamics, but i only consider the attendings as real adopters

                                                            list_I.append(
                                                                G.node[doctor]
                                                                ["label"])

                        new_num_adopters = len(list_I)

                        if shift_length == 5:  # i estimate that adoption happens in the middle of the shift
                            if t + 5 < cutting_day:
                                list_single_t_evolution.append(
                                    old_num_adopters)
                            if t + 4 < cutting_day:
                                list_single_t_evolution.append(
                                    old_num_adopters)
                            if t + 3 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)
                            if t + 2 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)
                            if t + 1 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)
                            t += 5

                        elif shift_length == 4:
                            if t + 4 < cutting_day:
                                list_single_t_evolution.append(
                                    old_num_adopters)
                            if t + 3 < cutting_day:
                                list_single_t_evolution.append(
                                    old_num_adopters)

                            if t + 2 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)

                            if t + 1 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)
                            t += 4

                        elif shift_length == 3:
                            if t + 3 < cutting_day:
                                list_single_t_evolution.append(
                                    old_num_adopters)

                            if t + 2 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)

                            if t + 1 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)

                            t += 3

                        elif shift_length == 2:
                            if t + 2 < cutting_day:
                                list_single_t_evolution.append(
                                    old_num_adopters)

                            if t + 1 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)

                            t += 2

                        elif shift_length == 1:
                            if t + 1 < cutting_day:
                                list_single_t_evolution.append(
                                    new_num_adopters)

                            t += 1

                        old_num_adopters = new_num_adopters

                    ######## end t loop

                    list_lists_t_evolutions.append(list_single_t_evolution)

                    list_dist_fixed_parameters.append(
                        compare_real_evol_vs_simus_to_be_called.
                        compare_two_curves(list_actual_evol_training,
                                           list_single_t_evolution))

                    list_dist_abs_at_ending_point_fixed_parameters.append(
                        abs(list_single_t_evolution[-1] -
                            list_actual_evol_training[-1])
                    )  # i save the distance at the ending point between the current simu and actual evol

                    #  print "actual:",len(list_actual_evol_training),"  simu:",len(list_single_t_evolution)   # 125, 125

                    list_final_num_infected.append(list_single_t_evolution[-1])

                    list_dist_at_ending_point_fixed_parameters.append(
                        list_single_t_evolution[-1] -
                        list_actual_evol_training[-1]
                    )  # i save the distance at the ending point between the current simu and actual evol

                    for n in G.nodes():
                        doctor = G.node[n]["label"]
                        if G.node[n]['type'] != "shift":
                            if G.node[n]['status'] == "I":
                                if G.node[n]['type'] == "F":
                                    dict_fellow_freq_adoption_end[doctor] += 1.
                                    num_F_adopters += 1.
                                elif G.node[n]['type'] == "A":
                                    dict_att_freq_adoption_end[doctor] += 1.
                                    num_Att_adopters += 1.

                ######## end loop Niter for the training fase

                list_pair_dist_std_delta_end = []

                list_pair_dist_std_delta_end.append(
                    numpy.mean(list_dist_fixed_parameters)
                )  # average dist between the curves over Niter
                list_pair_dist_std_delta_end.append(
                    numpy.std(list_dist_fixed_parameters))

                list_pair_dist_std_delta_end.append(
                    numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

                if print_landscape == "YES":
                    file3 = open(output_file3,
                                 'at')  # i print out the landscape
                    print >> file3, prob_infection, prob_Immune, infect_threshold, dose, numpy.mean(
                        list_dist_abs_at_ending_point_fixed_parameters
                    ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                        list_final_num_infected), numpy.std(
                            list_final_num_infected
                        ), numpy.std(list_final_num_infected) / numpy.mean(
                            list_final_num_infected)
                    file3.close()

                if print_training_evol == "YES":
                    file2 = open(output_file2, 'wt')
                    for s in range(len(list_single_t_evolution)):
                        list_fixed_t = []
                        for iter in range(Niter):
                            list_fixed_t.append(
                                list_lists_t_evolutions[iter][s])
                        print >> file2, s, numpy.mean(list_fixed_t)
                        last_adoption_value = numpy.mean(list_fixed_t)
                    file2.close()
                    print "written evolution file:", output_file2

                    print "\nFraction of times each fellow was an adopter at the end of the training segment:"
                    for n in G.nodes():
                        if G.node[n]['type'] == "F":
                            doctor = G.node[n]["label"]
                            dict_fellow_freq_adoption_end[
                                doctor] = dict_fellow_freq_adoption_end[
                                    doctor] / float(Niter)

                    sorted_list_tuples = sorted(
                        dict_fellow_freq_adoption_end.iteritems(),
                        key=operator.itemgetter(1),
                        reverse=True)

                    file4 = open(output_file4, 'wt')
                    print >> file4, last_adoption_value, "(value adoption among Att at cutting day)", "Avg # F adopters", num_F_adopters / Niter, "Avg # A adopters", num_Att_adopters / Niter
                    for pair in sorted_list_tuples:
                        print >> file4, pair[0], pair[1]
                    file4.close()
                    print "written adoption frecuency file for fellows:", output_file4

                value = numpy.mean(list_dist_fixed_parameters) * numpy.mean(
                    list_dist_abs_at_ending_point_fixed_parameters
                )  # if SD=0, it is a problem, because then that is the minimun value, but not the optimum i am looking for!!

                dict_filenames_prod_distances[output_file2] = value

                if (
                        numpy.mean(
                            list_dist_abs_at_ending_point_fixed_parameters)
                ) <= delta_end:  # i only consider situations close enough at the ending point

                    dict_filenames_tot_distance[
                        output_file2] = list_pair_dist_std_delta_end

                dose += delta_dose
            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

    if print_training_evol == "NO":  #if i am exploring the whole space

        string_name = "infection_memory_training_" + fixed_param + str(
            Niter
        ) + "iter_day" + str(
            cutting_day
        ) + "_Att_only_middle.dat"  # for the "Results" file with the sorted list of files
        list_order_dict = compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
            dict_filenames_tot_distance, string_name, Niter, cutting_day)

        # it returns a list of tuples like this :  ('../Results/network_final_schedule_withTeam3_local/infection/Average_time_evolution_Infection_training_p0.7_Immune0.0_2iter_2012.dat', [2540.0, 208.0, 1.0])  the best set of parameters  being the fist one of the elements in the list.

        list_order_dict2 = compare_real_evol_vs_simus_to_be_called.pick_minimum_prod_distances(
            dict_filenames_prod_distances, string_name, Niter, cutting_day)

    if print_landscape == "YES":
        print "printed out landscape file:", output_file3
def main(graph_name):

    G = nx.read_gml(graph_name)

    cutting_day = 125  # to separate   training-testing

    Niter_training = 100
    Niter_testing = 100

    delta_end = 3  # >= than + or -  dr difference at the end of the evolution

    dir_real_data = '../Results/'

    all_team = "NO"  # as adopters or not

    # output_file3=dir_real_data+"Landscape_parameters_persuasion_"+str(Niter)+"iter.dat"
    #file3 = open(output_file3,'wt')

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    if all_team == "YES":
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_all_team_as_adopters_SIMPLER.csv"

    else:
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_SIMPLER.csv"
    #ya no necesito CAMBIAR TB EL NOMBRE DEL ARCHIVO EN EL CODIGO PARA COMPARAR CURVAs

    list_actual_evol = []
    result_actual_file = csv.reader(open(filename_actual_evol, 'rb'),
                                    delimiter=',')
    cont = 0
    for row in result_actual_file:
        if cont > 0:  # i ignore the first line with the headers

            num_adopters = row[3]

            list_actual_evol.append(float(num_adopters))

        cont += 1

    list_actual_evol_training = list_actual_evol[:cutting_day]
    list_actual_evol_testing = list_actual_evol[(cutting_day - 1):]

    ##################################################################

    #../Results/network_final_schedule_withTeam3/Time_evolutions_Persuasion_alpha0.2_damping0.0_mutual_encourg0.7_threshold0.4_unif_distr_50iter_2012_seed31Oct_finalnetwork.dat

    alpha_F_min = 0.0  # alpha=0: nobody changes their mind
    alpha_F_max = 1.001
    delta_alpha_F = 0.1

    min_damping = 0.0  #its harder to go back from YES to NO again. =1 means no effect, =0.5 half the movement from Y->N than the other way around, =0 never go back from Y to N
    max_damping = 1.01
    delta_damping = 0.1

    min_mutual_encouragement = 0.0  # when two Adopters meet, they convince each other even more
    max_mutual_encouragement = 1.01
    delta_mutual_encouragement = 0.1

    print "\n\nPersuasion process on network, with Niter:", Niter_training

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    dict_filenames_list_dict_network_states = {}

    alpha_F = alpha_F_min
    while alpha_F <= alpha_F_max:  # i explore all the parameter space, and create a file per each set of values
        alpha_A = 0.5 * alpha_F
        print "  alpha_F:", alpha_F

        mutual_encouragement = min_mutual_encouragement
        while mutual_encouragement <= max_mutual_encouragement:
            print "    mutual_encouragement:", mutual_encouragement

            damping = min_damping
            while damping <= max_damping:
                print "      damping:", damping

                dir = "../Results/network_final_schedule_withTeam3_local/"
                output_file = dir + "Time_evolutions_Persuasion_training_alpha" + str(
                    alpha_F
                ) + "_damping" + str(damping) + "_mutual_encourg" + str(
                    mutual_encouragement) + "_" + str(
                        Niter_training) + "iter_distributed_thresholds.dat"
                file = open(output_file, 'wt')
                file.close()

                time_evol_number_adopters_ITER = [
                ]  # list of complete single realizations of the dynamics
                list_dist_fixed_parameters = []
                list_dist_abs_at_ending_point_fixed_parameters = []

                list_dict_network_states = []
                list_networks_at_cutting_day = []

                for iter in range(Niter_training):

                    print "         ", iter
                    list_t = []

                    time_evol_number_adopters = [
                    ]  # for a single realization of the dynamics

                    dict_network_states = {}

                    num_adopters, seed_shift, max_shift = set_ic(
                        G
                    )  # i establish who is Adopter and NonAdopter initially, and count how many shifts i have total

                    time_evol_number_adopters.append(float(num_adopters))
                    list_t.append(0)

                    ########### the dynamics starts:
                    t = int(
                        seed_shift) + 1  # the first time step is just IC.???

                    while t < cutting_day:  # loop over shifts, in chronological order  (the order is the day index since seeding_day)

                        list_t.append(t)
                        for n in G.nodes():
                            if G.node[n]['type'] == "shift" and G.node[n][
                                    'order'] == t:  # i look for the shift corresponding to that time step
                                flag_possible_persuasion = 0
                                for doctor in G.neighbors(n):
                                    if G.node[doctor][
                                            "status"] == "Adopter":  #first i check if any doctor is an adopter in this shift
                                        flag_possible_persuasion = 1
                                        break

                                if flag_possible_persuasion == 1:
                                    list_doctors = []
                                    for doctor in G.neighbors(
                                            n):  # for all drs in that shift
                                        list_doctors.append(doctor)

                                    pairs = itertools.combinations(
                                        list_doctors, 2
                                    )  # cos the shift can be 2 but also 3 doctors
                                    for pair in pairs:
                                        doctor1 = pair[0]
                                        doctor2 = pair[1]

                                        if G.node[doctor1]['status'] != G.node[
                                                doctor2][
                                                    'status']:  # if they think differently,
                                            # there will be persuasion
                                            persuasion(
                                                G, damping, doctor1, doctor2,
                                                alpha_A, alpha_F
                                            )  # i move their values of opinion
                                            update_opinions(
                                                G, doctor1, doctor2
                                            )  #  i update status and make sure the values of the vectors stay between [0,1]

                                        else:  # if two Adopters meet, they encourage each other (if two NonAdopters, nothing happens)

                                            mutual_reinforcement(
                                                G, mutual_encouragement,
                                                doctor1, doctor2)

                        list_Adopters = []  #count how many i have at this time
                        for n in G.nodes():
                            try:
                                if G.node[n]["status"] == "Adopter":
                                    if G.node[n]["label"] not in list_Adopters:
                                        list_Adopters.append(
                                            G.node[n]["label"])
                            except:
                                pass  # if the node is a shift, it doesnt have a 'status' attribute

                        time_evol_number_adopters.append(
                            float(len(list_Adopters)))

                        t += 1

                    ############## end while loop over t

                    for n in G.nodes():
                        if G.node[n]['type'] != "shift":
                            dict_network_states[
                                G.node[n]["label"]] = G.node[n]["status"]

                    list_dict_network_states.append(dict_network_states)

                    time_evol_number_adopters_ITER.append(
                        time_evol_number_adopters)

                    list_dist_fixed_parameters.append(
                        compare_real_evol_vs_simus_to_be_called.
                        compare_two_curves(list_actual_evol_training,
                                           time_evol_number_adopters))

                    list_dist_abs_at_ending_point_fixed_parameters.append(
                        abs(time_evol_number_adopters[-1] -
                            list_actual_evol_training[-1]))

                #######################   end loop Niter for the training fase

                list_pair_dist_std_delta_end = []

                list_pair_dist_std_delta_end.append(
                    numpy.mean(list_dist_fixed_parameters)
                )  # average dist between the curves over Niter
                list_pair_dist_std_delta_end.append(
                    numpy.std(list_dist_fixed_parameters))

                list_pair_dist_std_delta_end.append(
                    numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

                if (
                        numpy.mean(
                            list_dist_abs_at_ending_point_fixed_parameters)
                ) <= delta_end:  # i only consider situations close enough at the ending point

                    dict_filenames_tot_distance[
                        output_file] = list_pair_dist_std_delta_end

                    #print >> file3, alpha_F,damping,mutual_encouragement,threshold,dict_filenames_tot_distance[output_file][0],dict_filenames_tot_distance[output_file][1]

                    dict_filenames_list_dict_network_states[
                        output_file] = list_dict_network_states

                file = open(output_file, 'wt')
                for i in range(len(
                        time_evol_number_adopters)):  #time step by time step
                    list_fixed_t = []
                    for iteracion in range(
                            Niter_training
                    ):  #loop over all independent iter of the process
                        list_fixed_t.append(
                            time_evol_number_adopters_ITER[iteracion][i]
                        )  # i collect all values for the same t, different iter

                    print >> file, list_t[i], numpy.mean(
                        list_fixed_t), numpy.std(
                            list_fixed_t
                        ), alpha_F, damping, mutual_encouragement
                file.close()

                damping += delta_damping
            mutual_encouragement += delta_mutual_encouragement
        alpha_F += delta_alpha_F

    list_order_dict = compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
        dict_filenames_tot_distance,
        "Persuasion_training_distributed_thresholds", all_team, Niter_training)

    #./Results/network_final_schedule_withTeam3_local/Time_evolutions_Persuasion_alpha0.4_damping0.4_mutual_encourg0.6_threshold0.5_unif_distr_2iter_2012_seed31Oct_finalnetwork.dat

    optimum_filename = list_order_dict[0][0]

    alpha_F = float(list_order_dict[0][0].split("_alpha")[1][0:3])
    alpha_A = 0.5 * alpha_F
    damping = float(list_order_dict[0][0].split("_damping")[1][0:3])
    mutual_encouragement = float(
        list_order_dict[0][0].split("_mutual_encourg")[1][0:3])

    #   raw_input()
    print "starting testing fase with:"
    print "alpha=", alpha_F, " damping=", damping, " mutual encourag=", mutual_encouragement, " distributed threshold"

    #  i already know the optimum, now i run the dynamics with those values, starting from the average state on the cutting point, and test:

    time_evol_number_adopters_ITER = [
    ]  # list of complete single realizations of the dynamics

    list_dict_network_states = []

    list_dist_fixed_parameters = []
    list_dist_at_ending_point_fixed_parameters = []
    list_dist_abs_at_ending_point_fixed_parameters = []

    list_lists_t_evolutions = []

    lista_num_adopters = []
    lista_Adopters = []
    dict_tot_Adopters = {}

    for dictionary in dict_filenames_list_dict_network_states[
            optimum_filename]:
        # dictionary={Dr1:status, Dr2:status,}  # one dict per iteration
        num_Adopters = 0.

        for key in dictionary:
            if dictionary[key] == "Adopter":
                num_Adopters += 1.
                if key not in lista_Adopters:
                    lista_Adopters.append(key)
                    dict_tot_Adopters[key] = 1.
                else:
                    dict_tot_Adopters[key] += 1.

        lista_num_adopters.append(num_Adopters)

    avg_adopters = int(
        numpy.mean(lista_num_adopters))  # i find out the average num Adopters
    print numpy.mean(lista_num_adopters), avg_adopters, numpy.std(
        lista_num_adopters)

    if numpy.mean(lista_num_adopters) - avg_adopters >= 0.5:
        avg_adopters += 1.0
        print avg_adopters

# i sort the list from more frequently infected to less
    list_sorted_dict = sorted(dict_tot_Adopters.iteritems(),
                              key=operator.itemgetter(1))

    new_list_sorted_dict = list_sorted_dict
    new_list_sorted_dict.reverse()

    print "Adopters:", new_list_sorted_dict

    #list_sorted_dict=[(u'Weiss', 5.0), (u'Wunderink', 5.0), (u'Keller', 4.0), (u'Go', 3.0), (u'Cuttica', 3.0), (u'Rosario', 2.0), (u'Radigan', 2.0), (u'Smith', 2.0), (u'RosenbergN', 2.0), (u'Gillespie', 1.0), (u'Osher', 1.0), (u'Mutlu', 1.0), (u'Dematte', 1.0), (u'Hawkins', 1.0), (u'Gates', 1.0)]

    lista_avg_Adopters = [
    ]  # i create the list of Drs that on average are most likely infected by the cutting day

    i = 1
    for item in new_list_sorted_dict:
        if (item[0] not in lista_avg_Adopters) and (i <= avg_adopters):

            lista_avg_Adopters.append(item[0])
            i += 1

    print lista_avg_Adopters

    for iter in range(Niter_testing):

        print "         ", iter

        dict_dr_status_current_iter = dict_filenames_list_dict_network_states[
            optimum_filename][iter]

        time_evol_number_adopters = [
        ]  # for a single realization of the dynamics

        dict_network_states = {}

        list_t = []

        ###############
        # NECESITO GUARDAR RECORD DE LOS THERSHOLDS PERSONALES PARA USARLOS LUEGO aki???
        ########

        list_Adopters = []  #set initial conditions
        for node in G.nodes():
            if G.node[node]['type'] != "shift":

                # personal threshold have been established for each dr at the beginning of the simu: set_ic()

                G.node[node][
                    "status"] = "NonAdopter"  # by default,  non-Adopters

                label = G.node[node]['label']

                if label in lista_avg_Adopters:

                    G.node[node]["status"] = "Adopter"
                    G.node[node]["adoption_vector"] = random.random() * (
                        1.0 -
                        G.node[node]["personal_threshold"]) + G.node[node][
                            "personal_threshold"]  #values from (threshold,1]
                    if G.node[node]["adoption_vector"] > 1.0:
                        G.node[node]["adoption_vector"] = 1.0

                    list_Adopters.append(G.node[node]["label"])

        time_evol_number_adopters.append(float(len(list_Adopters)))
        list_t.append(cutting_day)

        ################# the dynamics starts for the testing fase:

        t = cutting_day

        while t <= max_shift:  # loop over shifts, in chronological order  (the order is the day index since seeding_day)

            list_t.append(t)
            for n in G.nodes():
                if G.node[n]['type'] == "shift" and G.node[n][
                        'order'] == t:  # i look for the shift corresponding to that time step
                    flag_possible_persuasion = 0
                    for doctor in G.neighbors(n):
                        if G.node[doctor][
                                "status"] == "Adopter":  #first i check if any doctor is an adopter in this shift
                            flag_possible_persuasion = 1
                            break

                    if flag_possible_persuasion == 1:
                        list_doctors = []
                        for doctor in G.neighbors(
                                n):  # for all drs in that shift
                            list_doctors.append(doctor)

                        pairs = itertools.combinations(
                            list_doctors,
                            2)  # cos the shift can be 2 but also 3 doctors
                        for pair in pairs:
                            doctor1 = pair[0]
                            doctor2 = pair[1]

                            if G.node[doctor1]['status'] != G.node[doctor2][
                                    'status']:  # if they think differently,
                                # there will be persuasion
                                persuasion(
                                    G, damping, doctor1, doctor2, alpha_A,
                                    alpha_F)  # i move their values of opinion
                                update_opinions(
                                    G, doctor1, doctor2
                                )  #  i update status and make sure the values of the vectors stay between [0,1]

                            else:  # if two Adopters meet, they encourage each other (if two NonAdopters, nothing happens)

                                mutual_reinforcement(G, mutual_encouragement,
                                                     doctor1, doctor2)

            list_Adopters = []  #count how many i have at this time
            for n in G.nodes():
                try:
                    if G.node[n]["status"] == "Adopter":
                        if G.node[n]["label"] not in list_Adopters:
                            list_Adopters.append(G.node[n]["label"])
                except:
                    pass  # if the node is a shift, it doesnt have a 'status' attribute

            time_evol_number_adopters.append(float(len(list_Adopters)))
            print t, len(list_Adopters)

            t += 1

        ############## end while loop over t

        #raw_input()

        for n in G.nodes():
            if G.node[n]['type'] != "shift":
                dict_network_states[G.node[n]["label"]] = G.node[n]["status"]

        list_dict_network_states.append(dict_network_states)

        time_evol_number_adopters_ITER.append(time_evol_number_adopters)

        list_dist_fixed_parameters.append(
            compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                list_actual_evol_testing, time_evol_number_adopters))

        list_dist_abs_at_ending_point_fixed_parameters.append(
            abs(time_evol_number_adopters[-1] - list_actual_evol_testing[-1]))

        list_dist_at_ending_point_fixed_parameters.append(
            time_evol_number_adopters[-1] - list_actual_evol_testing[-1])

        #######################end loop over Niter for the testing fase

    list_pair_dist_std_delta_end = []

    list_pair_dist_std_delta_end.append(
        numpy.mean(list_dist_fixed_parameters
                   ))  # average dist between the curves over Niter
    list_pair_dist_std_delta_end.append(numpy.std(list_dist_fixed_parameters))

    list_pair_dist_std_delta_end.append(
        numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

    if (
            numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)
    ) <= delta_end:  # i only consider situations close enough at the ending point

        dict_filenames_tot_distance[output_file] = list_pair_dist_std_delta_end

        dict_filenames_list_dict_network_states[
            output_file] = list_dict_network_states

    num_valid_endings = 0.
    for item in list_dist_abs_at_ending_point_fixed_parameters:
        if item <= delta_end:  # i count how many realizations i get close enough at the ending point
            num_valid_endings += 1.

    print "average distance of the optimum in the testing segment:", numpy.mean(
        list_dist_fixed_parameters), numpy.std(
            list_dist_fixed_parameters), list_dist_fixed_parameters
    print "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter_testing, list_dist_abs_at_ending_point_fixed_parameters

    histograma_gral_negv_posit.histograma(
        list_dist_at_ending_point_fixed_parameters,
        "../Results/histogr_raw_distances_ending_test_train_persuasion_avg_ic_"
        + str(Niter_testing) + "iter_distributed_thresholds.dat")

    output_file8 = "../Results/List_tot_distances_training_segment_persuasion_alpha" + str(
        alpha_F) + "_damping" + str(damping) + "_mutual_encourg" + str(
            mutual_encouragement) + "_" + str(
                Niter_training) + "iter_avg_ic_distributed_thresholds.dat"
    file8 = open(output_file8, 'wt')

    for item in list_dist_fixed_parameters:
        print >> file8, item
    file8.close()

    output_file9 = "../Results/List_distances_ending_training_segment_persuasion_alpha" + str(
        alpha_F) + "_damping" + str(damping) + "_mutual_encourg" + str(
            mutual_encouragement) + "_" + str(
                Niter_training) + "iter_avg_ic_distributed_thresholds.dat"
    file9 = open(output_file9, 'wt')

    for item in list_dist_abs_at_ending_point_fixed_parameters:
        print >> file9, item
    file9.close()

    output_file = dir + "Time_evolutions_Persuasion_testing_avg_ic_alpha" + str(
        alpha_F
    ) + "_damping" + str(damping) + "_mutual_encourg" + str(
        mutual_encouragement
    ) + "_unif_distr_" + str(
        Niter_training
    ) + "iter_2012_seed31Oct_finalnetwork_avg_ic_distributed_thresholds.dat"
    file = open(output_file, 'wt')

    for i in range(len(time_evol_number_adopters)):  #time step by time step
        list_fixed_t = []
        for iteracion in range(
                Niter_training
        ):  #loop over all independent iter of the process
            list_fixed_t.append(
                time_evol_number_adopters_ITER[iteracion]
                [i])  # i collect all values for the same t, different iter

        print >> file, list_t[i], numpy.mean(list_fixed_t), numpy.std(
            list_fixed_t), alpha_F, damping, mutual_encouragement
    file.close()

    print "written training segment file:", optimum_filename
    print "written testing segment file:", output_file

    output_file10 = "../Results/Summary_results_train_test_persuasion_alpha" + str(
        alpha_F) + "_damping" + str(damping) + "_mutual_encourg" + str(
            mutual_encouragement) + "_" + str(
                Niter_training) + "iter_avg_ic_distributed_thresholds.dat"
    file10 = open(output_file10, 'wt')

    print >> file10, "Summary results from train-testing persuasion with", Niter_training, Niter_testing, "iter (respectively), using the avg of the cutting points as IC, and with values for the parameters:  alpha ", alpha_F, " damping: ", damping, " mutual_encourg: ", mutual_encouragement, " distributed threshold"

    print >> file10, "average distance of the optimum in the testing segment:", numpy.mean(
        list_dist_fixed_parameters), numpy.std(
            list_dist_fixed_parameters), list_dist_fixed_parameters
    print >> file10, "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter_testing, list_dist_at_ending_point_fixed_parameters

    print >> file10, "written training segment file:", optimum_filename
    print >> file10, "written testing segment file:", output_file

    file10.close()
예제 #3
0
def main(graph_name):
 


   cutting_day=175  # to separate   training-testing





   G = nx.read_gml(graph_name)


   all_team="NO"   # as adopters or not

   list_id_weekends_T3=look_for_T3_weekends(G)  # T3 doesnt share fellows in the weekend  (but they are the exception)


   dir_real_data='../Results/'
   Nbins=20   # for the histogram of sum of distances


   delta_end=3.  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

   Niter=1000
  
   fixed_param=""#FIXED_Pimm0_"    # or ""  # for the Results file that contains the sorted list of best parameters


######################################################################################
#  I read the file of the actual evolution of the idea spreading in the hospital:   ##
######################################################################################



  
   filename_actual_evol="../Results/Actual_evolution_adopters_from_inference.dat"
  


   file1=open(filename_actual_evol,'r')         ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
   list_lines_file=file1.readlines()
            

   list_actual_evol=[]  
   for line in list_lines_file:      # [1:]:   # i exclude the first row   
     
      num_adopters= float(line.split("\t")[1])          
      list_actual_evol.append(num_adopters)



   list_actual_evol_training=list_actual_evol[:cutting_day]
  # list_actual_evol_testing=list_actual_evol[(cutting_day-1):]  # i dont need this one
   
  
##################################################################


   prob_min=0.10
   prob_max=1.01
   delta_prob=0.1
   
   

   prob_Immune_min=0.0    
   prob_Immune_max=1.001
   delta_prob_Immune=0.1

# threshold is not personal, and set randomly to a value (0,1)
 
                   # of a single encounter with an infected  (it cant be zero or it doesnt make sense!)
   dose_min=0.05              #infect_threshold_min
   dose_max=1.001         #######infect_threshold_min/10.
   delta_dose=0.05           ##infect_threshold_min/10.


   dir="../Results/weight_shifts/infection/"       

   dict_filenames_tot_distance={}   # i will save the filename as key and the tot distance from that curve to the original one
   dict_filenames_prod_distances={}   

  

   prob_Immune=prob_Immune_min
   while prob_Immune<= prob_Immune_max:
        
      print "prom Immune:",prob_Immune        

      prob_infection=prob_min
      while prob_infection<= prob_max:
                 
            print "  p:",prob_infection                              
            
            dose=dose_min
            while dose <= dose_max:
               
               print "  dose:",dose





               output_file2=dir+"Average_time_evolution_Infection_memory_training_p"+str(prob_infection)+"_"+"Immune"+str(prob_Immune)+"_threshold_from_distrib_dose"+str(dose)+"_"+str(Niter)+"iter_day"+str(cutting_day)+"_A_F_inferred.dat"
             #  file2 = open(output_file2,'wt')                                       
              # file2.close()
               



      
               list_lists_t_evolutions=[]     # i create the empty list of list for the Niter temporal evolutions
               
               list_dist_fixed_parameters=[]
               list_dist_at_ending_point_fixed_parameters=[]
               list_dist_abs_at_ending_point_fixed_parameters=[]
              
               
               for iter in range(Niter):
            
              #    print "     iter:",iter


               
                  

            ########### set I.C.


                  list_I=[]  #list infected doctors
                  max_order=0
                  for n in G.nodes():
                     G.node[n]["status"]="S"  # all nodes are Susceptible
                     G.node[n]["infec_value"]=0. 
                     G.node[n]["personal_threshold"]=random.random()  # for a dr to become infected

                     if G.node[n]['type']=="shift":                        
                        if  G.node[n]['order']>max_order:
                           max_order=G.node[n]['order'] # to get the last shift-order for the time loop
                     else:
                        if G.node[n]['label']=="Wunderink"  or G.node[n]["label"]=="Weiss":           
                           G.node[n]["status"]="I"                       
                           G.node[n]["infec_value"]=G.node[n]["personal_threshold"]+ 1.
                           list_I.append(G.node[n]['label'])
          

            
           
                  list_single_t_evolution=[]
                  list_single_t_evolution.append(2.0)  # I always start with TWO infected doctors!!


                  for n in G.nodes():   # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                     if (G.node[n]['type']=="A") or ( G.node[n]['type']=="F"):
                        if G.node[n]['label']!="Wunderink"  and G.node[n]["label"]!="Weiss": 
                           rand=random.random()
                           if rand< prob_Immune:
                              G.node[n]["status"]="Immune"
                              


        
  
                  ################# the dynamics starts: 
            
                  t=1
                  while t< cutting_day:  # loop over shifts, in order           
                     for n in G.nodes():
                        if G.node[n]['type']=="shift" and G.node[n]['order']==t:
                           shift_length=int(G.node[n]['shift_length'])

                           if shift_length==2 and n not in list_id_weekends_T3:
                              shift_length=1   # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)

                           flag_possible_infection=0
                           for doctor in G.neighbors(n): #first i check if any doctor is infected in this shift
                              if G.node[doctor]["status"]=="I":
                                 flag_possible_infection=1
                                

                           if flag_possible_infection:
                              for doctor in G.neighbors(n): # then the doctors in that shift, gets infected with prob_infection

                                 for i in range(shift_length):   # i repeat the infection process several times, to acount for shift lenght
                                    if G.node[doctor]["status"]=="S":
                                       rand=random.random()
                                       if rand<prob_infection:  # with prob p the infection occurres
                                          
                                          G.node[doctor]["infec_value"]+=dose  # and bumps the infection_value of that susceptible dr
                                          
                                          if G.node[doctor]["infec_value"]>= G.node[doctor]["personal_threshold"]:  # the threshold for infection is personal
                                             
                                             G.node[doctor]["status"]="I"
                                             
                                        
                                                
                                             list_I.append(G.node[doctor]["label"])
                                                

                     list_single_t_evolution.append(float(len(list_I)))

                     t+=1   
                     ######## end t loop





          


                  list_lists_t_evolutions.append(list_single_t_evolution)
             
 
                  #print "actual:",len(list_actual_evol_training),"  simu:",len(list_single_t_evolution)
                  list_dist_fixed_parameters.append(compare_real_evol_vs_simus_to_be_called.compare_two_curves( list_actual_evol_training,list_single_t_evolution))
                  
                  list_dist_abs_at_ending_point_fixed_parameters.append( abs(list_single_t_evolution[-1]-list_actual_evol_training[-1]) )   # i save the distance at the ending point between the current simu and actual evol
                  list_dist_at_ending_point_fixed_parameters.append( list_single_t_evolution[-1]-list_actual_evol_training[-1])    # i save the distance at the ending point between the current simu and actual evol

                           
                  ######## end loop Niter for the training fase
      

       


       
       
               list_pair_dist_std_delta_end=[]
               
               list_pair_dist_std_delta_end.append(numpy.mean(list_dist_fixed_parameters) )   # average dist between the curves over Niter
               list_pair_dist_std_delta_end.append(numpy.std(list_dist_fixed_parameters) )
               
               list_pair_dist_std_delta_end.append(numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))
               

               value=numpy.mean(list_dist_fixed_parameters) *numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)# if SD=0, it is a problem, because then that is the minimun value, but not the optimum i am looking for!!
    
               dict_filenames_prod_distances[output_file2]=  value

               
               if (numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)) <= delta_end:  # i only consider situations close enough at the ending point   
                  
                  dict_filenames_tot_distance[output_file2]=list_pair_dist_std_delta_end
                                                                                          

                  histogram_filename="../Results/weight_shifts/histogr_raw_distances_ending_infection_memory_training_p"+str(prob_infection)+"_"+"Immune"+str(prob_Immune)+"_threshold_from_distrib_dose"+str(dose)+"_"+str(Niter)+"iter_day"+str(cutting_day)+"_A_F_inferred.dat"
                  histograma_gral_negv_posit.histograma(list_dist_at_ending_point_fixed_parameters,histogram_filename)
                  
                  histogram_filename2="../Results/weight_shifts/histogr_sum_dist_traject_infection_memory_training_p"+str(prob_infection)+"_"+"Immune"+str(prob_Immune)+"_threshold_from_distrib_dose"+str(dose)+"_"+str(Niter)+"iter_day"+str(cutting_day)+"_A_F_inferred.dat"
                  
                  histograma_bines_gral.histograma_bins(list_dist_fixed_parameters,Nbins,histogram_filename2)
                  
                  
                  print  "written histogram file: ",histogram_filename
                  print  "written histogram file: ",histogram_filename2


               dose+= delta_dose          
            prob_infection+= delta_prob
      prob_Immune+= delta_prob_Immune



 

   string_name="infection_memory_training_"+fixed_param+str(Niter)+"iter_day"+str(cutting_day)+"_A_F_inferred.dat"   # for the "Results" file with the sorted list of files
   
   list_order_dict= compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(dict_filenames_tot_distance,string_name,Niter,cutting_day)
# it returns a list of tuples like this :  ('../Results/network_final_schedule_withTeam3_local/infection/Average_time_evolution_Infection_training_p0.7_Immune0.0_2iter_2012.dat', [2540.0, 208.0, 1.0])  the best set of parameters  being the fist one of the elements in that list.



   
   
   
   list_order_dict2= compare_real_evol_vs_simus_to_be_called.pick_minimum_prod_distances(dict_filenames_prod_distances,string_name,Niter,cutting_day)


   

   prob_infection=float(list_order_dict[0][0].split("_p")[1].split("_")[0])
   prob_Immune=float(list_order_dict[0][0].split("_Immune")[1].split("_")[0]) 
   dose=float(list_order_dict[0][0].split("_dose")[1].split("_")[0])
 
  
   
  
   print "\nOptimum parameters (old method) at day",cutting_day," are: p=",prob_infection," Pimmune=",prob_Immune," infection threshold from distribution, and dose=",dose
   


  # optimum_filename=list_order_dict2[0][0]

   prob_infection=float(list_order_dict2[0][0].split("_p")[1].split("_")[0])
   prob_Immune=float(list_order_dict2[0][0].split("_Immune")[1].split("_")[0])  
   dose=float(list_order_dict2[0][0].split("_dose")[1].split("_")[0])
 
  
 
   print "Optimum parameters (product of distances and SDs) at day",cutting_day," are: p=",prob_infection," Pimmune=",prob_Immune," infection threshold from distribution, and dose=",dose
예제 #4
0
def main(graph_name):

    G = nx.read_gml(graph_name)

    for_testing_fixed_set = "YES"  # when YES, fixed values param, to get all statistics on final distances etc
    # change the range for the parameters accordingly

    envelopes = "YES"

    Niter = 1000  # 100 iter seems to be enough (no big diff. with respect to 1000it)

    percent_envelope = 95.

    list_id_weekends_T3 = look_for_T3_weekends(
        G
    )  # T3 doesnt share fellows in the weekend  (but they are the exception)
    Nbins = 20  # for the histogram of sum of distances

    cutting_day = 175  # i use this only for the filenames

    all_team = "NO"  # as adopters or not

    dir_real_data = '../Results/'
    dir = "../Results/weight_shifts/infection/"

    delta_end = 3.  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

    if for_testing_fixed_set == "NO":
        output_file3 = "../Results/weight_shifts/Landscape_parameters_infection_" + str(
            Niter) + "iter.dat"
        file3 = open(output_file3, 'wt')

        file3.close()

######################################################################################
#  I read the file of the actual evolution of the idea spreading in the hospital:   ##
######################################################################################

    if all_team == "YES":
        print "remember that now i use the file of adopters without fellows\n../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
        exit()

    else:
        filename_actual_evol = "../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"

    file1 = open(
        filename_actual_evol, 'r'
    )  ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
    list_lines_file = file1.readlines()

    list_actual_evol = []
    for line in list_lines_file:  # [1:]:   # i exclude the first row

        num_adopters = float(line.split(" ")[1])
        list_actual_evol.append(num_adopters)

##################################################################

#../Results/weight_shifts/infection/Average_time_evolution_Infection_training_p0.8_Immune0.3_1000iter_2012_avg_ic_day125.dat ESTOS VALORES SON EL OPTIMUM FIT THE 152-DIAS
    prob_min = 0.1
    prob_max = 0.101
    delta_prob = 0.1

    prob_Immune_min = 0.00
    prob_Immune_max = 0.001
    delta_prob_Immune = 0.1

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            if for_testing_fixed_set == "YES":
                output_file2 = dir + "Average_time_evolution_Infection_train_test_p" + str(
                    prob_infection) + "_" + "Immune" + str(
                        prob_Immune) + "_" + str(Niter) + "iter_2012.dat"

            else:
                output_file2 = dir + "Average_time_evolution_Infection_p" + str(
                    prob_infection) + "_" + "Immune" + str(
                        prob_Immune) + "_" + str(Niter) + "iter_2012.dat"

            file2 = open(output_file2, 'wt')
            file2.close()

            #  list_final_I_values_fixed_p=[]  # i dont care about the final values right now, but about the whole time evol
            list_lists_t_evolutions = []

            list_dist_fixed_parameters = []
            list_abs_dist_at_ending_point_fixed_parameters = []
            list_dist_at_ending_point_fixed_parameters = []
            list_final_num_infected = []

            #   list_abs_dist_at_cutting_day=[]

            for iter in range(Niter):

                #print "     iter:",iter

                #######OJO~!!!!!!!!!! COMENTAR ESTO CUANDO ESTOY BARRIENDO TOOOOOOOOOODO EL ESPACIO DE PARAMETROS
                #    file_name_indiv_evol=output_file2.strip("Average_").split('.dat')[0]+"_indiv_iter"+str(iter)+".dat"

                #   file4 = open(file_name_indiv_evol,'wt')
                #  file4.close()
                ##########################################

                ########### set I.C.

                list_I = []  #list infected doctors
                max_order = 0
                for n in G.nodes():
                    G.node[n]["status"] = "S"  # all nodes are Susceptible
                    if G.node[n]['type'] == "shift":
                        if G.node[n]['order'] > max_order:
                            max_order = G.node[n][
                                'order']  # to get the last shift-order for the time loop
                    else:
                        if G.node[n]['label'] == "Wunderink" or G.node[n][
                                "label"] == "Weiss":
                            G.node[n]["status"] = "I"
                            list_I.append(G.node[n]['label'])

                list_single_t_evolution = []
                list_single_t_evolution.append(
                    2.0)  # I always start with TWO infected doctors!!

                for n in G.nodes(
                ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                    if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                      == "F"):
                        if G.node[n]['label'] != "Wunderink" and G.node[n][
                                "label"] != "Weiss":
                            rand = random.random()
                            if rand < prob_Immune:
                                G.node[n]["status"] = "Immune"

                ################# the dynamics starts:

                t = 1
                while t <= max_order:  # loop over shifts, in order
                    for n in G.nodes():
                        if G.node[n]['type'] == "shift" and G.node[n][
                                'order'] == t:

                            shift_lenght = int(G.node[n]['shift_lenght'])

                            if shift_lenght == 2 and n not in list_id_weekends_T3:
                                shift_lenght = 1  # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)
                            #  print "one-day weekend", G.node[n]['label'],G.node[n]['shift_lenght']

                            flag_possible_infection = 0
                            for doctor in G.neighbors(
                                    n
                            ):  #first i check if any doctor is infected in this shift
                                if G.node[doctor]["status"] == "I":
                                    flag_possible_infection = 1

                            if flag_possible_infection:
                                for doctor in G.neighbors(
                                        n
                                ):  # then the doctors in that shift, gets infected with prob_infection

                                    for i in range(
                                            shift_lenght
                                    ):  # i repeat the infection process several times, to acount for shift lenght
                                        if G.node[doctor]["status"] == "S":
                                            rand = random.random()
                                            if rand < prob_infection:
                                                G.node[doctor]["status"] = "I"

                                                if G.node[doctor][
                                                        "type"] == "A":  # fellows participate in the dynamics, but i only consider the attendings as real adopters
                                                    list_I.append(
                                                        G.node[doctor]
                                                        ["label"])

                #  if for_testing_fixed_set=="YES":
                #    if t==cutting_day:
                #      list_abs_dist_at_cutting_day.append(abs(float(list_actual_evol[-1])-float(len(list_I))))
                #     print abs(float(list_actual_evol[-1])-float(len(list_I))), float(list_actual_evol[t]),float(len(list_I))

                    list_single_t_evolution.append(float(len(list_I)))

                    t += 1

                    ######## end t loop

                ########OJO~!!!!!!!!!! COMENTAR ESTO CUANDO ESTOY BARRIENDO TOOOOOOOOOODO EL ESPACIO DE PARAMETROS
            # file4 = open(file_name_indiv_evol,'at')
            #for i in range(len(list_single_t_evolution)):  #time step by time step
            #  print >> file4, i,list_single_t_evolution[i], prob_infection, prob_Immune
            #file4.close()
            ########################################################

                list_lists_t_evolutions.append(list_single_t_evolution)

                list_dist_fixed_parameters.append(
                    compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                        list_actual_evol, list_single_t_evolution))

                list_abs_dist_at_ending_point_fixed_parameters.append(
                    abs(list_single_t_evolution[-1] - list_actual_evol[-1])
                )  # i save the distance at the ending point between the current simu and actual evol
                list_dist_at_ending_point_fixed_parameters.append(
                    list_single_t_evolution[-1] - list_actual_evol[-1]
                )  # i save the distance at the ending point between the current simu and actual evol
                list_final_num_infected.append(list_single_t_evolution[-1])

            ######## end loop Niter

            list_pair_dist_std_delta_end = []

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_fixed_parameters)
            )  # average dist between the curves over Niter
            list_pair_dist_std_delta_end.append(
                numpy.std(list_dist_fixed_parameters))

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_abs_dist_at_ending_point_fixed_parameters))

            if for_testing_fixed_set == "NO":
                file3 = open(output_file3, 'at')  # i print out the landscape
                print >> file3, prob_infection, prob_Immune, numpy.mean(
                    list_abs_dist_at_ending_point_fixed_parameters
                ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                    list_final_num_infected), numpy.std(
                        list_final_num_infected)
                file3.close()

            if (
                    numpy.mean(list_abs_dist_at_ending_point_fixed_parameters)
            ) <= delta_end:  # i only consider situations close enough at the ending point

                dict_filenames_tot_distance[
                    output_file2] = list_pair_dist_std_delta_end

            file2 = open(output_file2, 'at')
            for s in range(len(list_single_t_evolution)):
                list_fixed_t = []
                for iter in range(Niter):
                    list_fixed_t.append(list_lists_t_evolutions[iter][s])
                print >> file2, s, numpy.mean(list_fixed_t)
            file2.close()

            print "printed out: ", output_file2
            # raw_input()

            if envelopes == "YES":
                calculate_envelope_set_curves.calculate_envelope(
                    list_lists_t_evolutions, percent_envelope, "Infection",
                    [prob_infection, prob_Immune])

            if for_testing_fixed_set == "YES":

                num_valid_endings = 0.
                for item in list_abs_dist_at_ending_point_fixed_parameters:
                    if item <= delta_end:  # i count how many realizations i get close enough at the ending point
                        num_valid_endings += 1.

                print "average distance of the optimum in the testing segment:", numpy.mean(
                    list_dist_fixed_parameters), numpy.std(
                        list_dist_fixed_parameters
                    ), list_dist_fixed_parameters, "\n"
                print "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter, "mean ending dist:", numpy.mean(
                    list_dist_at_ending_point_fixed_parameters
                ), "SD final dist", numpy.std(
                    list_dist_at_ending_point_fixed_parameters
                ), list_dist_at_ending_point_fixed_parameters, "\n"

                histogram_filename = "../Results/weight_shifts/histogr_raw_distances_ending_infection_p" + str(
                    prob_infection) + "_" + "Immune" + str(
                        prob_Immune) + "_" + str(Niter) + "iter_day" + str(
                            cutting_day) + ".dat"
                histograma_gral_negv_posit.histograma(
                    list_dist_at_ending_point_fixed_parameters,
                    histogram_filename)

                histogram_filename2 = "../Results/weight_shifts/histogr_sum_dist_traject_infection_p" + str(
                    prob_infection) + "_" + "Immune" + str(
                        prob_Immune) + "_" + str(Niter) + "iter_day" + str(
                            cutting_day) + ".dat"

                histograma_bines_gral.histograma_bins(
                    list_dist_fixed_parameters, Nbins, histogram_filename2)

                output_file10 = "../Results/weight_shifts/Summary_results_training_segment_infection_p" + str(
                    prob_infection) + "_" + "Immune" + str(
                        prob_Immune) + "_" + str(Niter) + "iter_day" + str(
                            cutting_day) + ".dat"
                file10 = open(output_file10, 'wt')

                print >> file10, "Summary results from train-testing infection with", Niter, "iter, and with values for the parameters:  prob_inf ", prob_infection, " prob immune: ", prob_Immune, "\n"

                print >> file10, "average distance of the optimum in the testing segment:", numpy.mean(
                    list_dist_fixed_parameters), numpy.std(
                        list_dist_fixed_parameters
                    ), list_dist_fixed_parameters, "\n"
                print >> file10, "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter, "mean ending dist:", numpy.mean(
                    list_dist_at_ending_point_fixed_parameters
                ), "SD final dist", numpy.std(
                    list_dist_at_ending_point_fixed_parameters
                ), list_dist_at_ending_point_fixed_parameters, "\n"

                print >> file10, "written optimum train_test evolution file:", output_file2
                print >> file10, "written histogram file: ", histogram_filename

                file10.close()

                print "written Summary file: ", output_file10
                print "written histogram file: ", histogram_filename
                print "written histogram file: ", histogram_filename2

            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

    if for_testing_fixed_set == "NO":  # only if i am exploring the whole landscape, i need to call this function, otherwise, i already know the optimum
        compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
            dict_filenames_tot_distance, "Infection_weight", all_team, Niter,
            None)  # last argument doesnt apply (cutting day)

    if for_testing_fixed_set == "NO":
        print "written landscape file:", output_file3
예제 #5
0
def main(graph_name):

    cutting_day = 125  # to separate   training-testing

    G = nx.read_gml(graph_name)

    all_team = "NO"  # as adopters or not

    dir_real_data = '../Results/'

    delta_end = 3  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

    Niter_training = 100
    Niter_testing = 100

    output_file3 = dir_real_data + "Landscape_parameters_infection_train_test_" + str(
        Niter_training) + "iter.dat"
    file3 = open(output_file3, 'wt')

    file3.close()

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    if all_team == "YES":
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_all_team_as_adopters_SIMPLER.csv"

    else:
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_SIMPLER.csv"
    #ya no necesito CAMBIAR TB EL NOMBRE DEL ARCHIVO EN EL CODIGO PARA COMPARAR CURVAs

    list_actual_evol = []
    result_actual_file = csv.reader(open(filename_actual_evol, 'rb'),
                                    delimiter=',')
    cont = 0
    for row in result_actual_file:
        if cont > 0:  # i ignore the first line with the headers

            num_adopters = row[3]

            list_actual_evol.append(float(num_adopters))

        cont += 1

    list_actual_evol_training = list_actual_evol[:cutting_day]
    list_actual_evol_testing = list_actual_evol[(cutting_day - 1):]

    ##################################################################

    #../Results/network_final_schedule_withTeam3/infection/Average_time_evolution_Infection_p0.9_Immune0.5_1000iter_2012.dat

    prob_min = 0.0
    prob_max = 1.001
    delta_prob = 0.01

    prob_Immune_min = 0.00
    prob_Immune_max = 1.001
    delta_prob_Immune = 0.01

    dir = "../Results/network_final_schedule_withTeam3_local/infection/"

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    dict_filenames_list_dict_network_states = {
    }  # i will save the filename as key and the list of networks at cutting day as value

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            output_file2 = dir + "Average_time_evolution_Infection_training_p" + str(
                prob_infection) + "_" + "Immune" + str(
                    prob_Immune) + "_" + str(
                        Niter_training) + "iter_2012_avg_ic_day" + str(
                            cutting_day) + ".dat"
            file2 = open(output_file2, 'wt')
            file2.close()

            # i create the empty list of list for the Niter temporal evolutions
            num_shifts = 0
            num_Drs = 0.
            for n in G.nodes():
                G.node[n]["status"] = "S"
                if G.node[n]['type'] == "shift":
                    num_shifts += 1
                else:
                    num_Drs += 1.

        #  list_final_I_values_fixed_p=[]  # i dont care about the final values right now, but about the whole time evol
            list_lists_t_evolutions = []

            list_dist_fixed_parameters = []
            list_dist_abs_at_ending_point_fixed_parameters = []
            list_final_num_infected = []
            list_dict_network_states = []

            for iter in range(Niter_training):

                print "     iter:", iter

                dict_network_states = {}

                list_I = []  #list infected doctors
                list_ordering = []
                list_s = []
                list_A = []
                list_F = []

                ########### set I.C.

                max_order = 0
                for n in G.nodes():
                    G.node[n]["status"] = "S"  # all nodes are Susceptible
                    if G.node[n]['type'] == "shift":
                        list_s.append(n)
                        if G.node[n]['order'] > max_order:
                            max_order = G.node[n]['order']
                    else:
                        if G.node[n]['label'] == "Wunderink" or G.node[n][
                                "label"] == "Weiss":
                            G.node[n]["status"] = "I"
                            list_I.append(G.node[n]['label'])

                        if G.node[n]['type'] == "A":
                            list_A.append(n)

                        if G.node[n]['type'] == "F":
                            list_F.append(n)

                list_single_t_evolution = []
                list_single_t_evolution.append(
                    2.0)  # I always start with TWO infected doctors!!

                for n in G.nodes(
                ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                    if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                      == "F"):
                        if G.node[n]['label'] != "Wunderink" and G.node[n][
                                "label"] != "Weiss":
                            rand = random.random()
                            if rand < prob_Immune:
                                G.node[n]["status"] = "Immune"

            #   print max_order

            ################# the dynamics starts:

                t = 1
                while t < cutting_day:  # loop over shifts, in order   just until cutting day (training segment)
                    for n in G.nodes():
                        if G.node[n]['type'] == "shift" and G.node[n][
                                'order'] == t:
                            flag_possible_infection = 0
                            for doctor in G.neighbors(
                                    n
                            ):  #first i check if any doctor is infected in this shift
                                if G.node[doctor]["status"] == "I":
                                    flag_possible_infection = 1

                            if flag_possible_infection:
                                for doctor in G.neighbors(
                                        n
                                ):  # then the doctors in that shift, gets infected with prob_infection
                                    if G.node[doctor]["status"] == "S":
                                        rand = random.random()
                                        if rand < prob_infection:
                                            G.node[doctor]["status"] = "I"
                                            list_I.append(
                                                G.node[doctor]["label"])

                    list_single_t_evolution.append(float(
                        len(list_I)))  #/(len(list_A)+len(list_F)))

                    t += 1
                ######## end t loop

                for n in G.nodes():
                    if G.node[n]['type'] != "shift":
                        dict_network_states[G.node[n]
                                            ["label"]] = G.node[n]["status"]

                list_dict_network_states.append(dict_network_states)

                list_lists_t_evolutions.append(list_single_t_evolution)

                list_dist_fixed_parameters.append(
                    compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                        list_actual_evol_training, list_single_t_evolution))

                list_dist_abs_at_ending_point_fixed_parameters.append(
                    abs(list_single_t_evolution[-1] -
                        list_actual_evol_training[-1])
                )  # i save the distance at the ending point between the current simu and actual evol

                #  print "actual:",len(list_actual_evol_training),"  simu:",len(list_single_t_evolution)   # 125, 125

                list_final_num_infected.append(list_single_t_evolution[-1])

            ######## end loop Niter for the training fase

            list_pair_dist_std_delta_end = []

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_fixed_parameters)
            )  # average dist between the curves over Niter
            list_pair_dist_std_delta_end.append(
                numpy.std(list_dist_fixed_parameters))

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

            file3 = open(output_file3, 'at')  # i print out the landscape
            print >> file3, prob_infection, prob_Immune, numpy.mean(
                list_dist_abs_at_ending_point_fixed_parameters
            ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                list_final_num_infected
            ), numpy.std(list_final_num_infected), numpy.std(
                list_final_num_infected) / numpy.mean(list_final_num_infected)
            file3.close()

            if (
                    numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)
            ) <= delta_end:  # i only consider situations close enough at the ending point

                dict_filenames_tot_distance[
                    output_file2] = list_pair_dist_std_delta_end

                dict_filenames_list_dict_network_states[
                    output_file2] = list_dict_network_states

            file2 = open(output_file2, 'at')
            for s in range(len(list_single_t_evolution)):
                list_fixed_t = []
                for iter in range(Niter_training):
                    list_fixed_t.append(list_lists_t_evolutions[iter][s])
                print >> file2, s, numpy.mean(list_fixed_t)
            file2.close()

            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

    list_order_dict = compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
        dict_filenames_tot_distance, "Infection_training", all_team,
        Niter_training, cutting_day)

    # it returns a list of tuples like this :  ('../Results/network_final_schedule_withTeam3_local/infection/Average_time_evolution_Infection_training_p0.7_Immune0.0_2iter_2012.dat', [2540.0, 208.0, 1.0])  the best set of parameters  being the fist one of the elements in the list.

    optimum_filename = list_order_dict[0][0]
    prob_infection = float(list_order_dict[0][0].split("_p")[1].split("_")[0])
    prob_Immune = float(
        list_order_dict[0][0].split("_Immune")[1].split("_")[0])

    print "starting testing fase with:"
    print "p=", prob_infection, " and Pimmune=", prob_Immune

    #  i already know the optimum, now i run the dynamics with those values, starting from the average state on the cutting point, and test:

    list_dist_fixed_parameters = []
    list_dist_abs_at_ending_point_fixed_parameters = []
    list_dist_at_ending_point_fixed_parameters = []

    list_lists_t_evolutions = []

    lista_num_infect = []
    lista_I_drs = []
    dict_tot_I_doctors = {}

    lista_num_imm = []
    lista_Imm_drs = []
    dict_tot_Imm_doctors = {}
    for dictionary in dict_filenames_list_dict_network_states[
            optimum_filename]:

        # dictionary={Dr1:status, Dr2:status,}  # one dict per iteration
        num_I = 0.
        num_Imm = 0.

        for key in dictionary:
            if dictionary[key] == "I":
                num_I += 1.
                if key not in lista_I_drs:
                    lista_I_drs.append(key)
                    dict_tot_I_doctors[key] = 1.
                else:
                    dict_tot_I_doctors[key] += 1.

            elif dictionary[key] == "Immune":
                num_Imm += 1.
                if key not in lista_Imm_drs:
                    lista_Imm_drs.append(key)
                    dict_tot_Imm_doctors[key] = 1.
                else:
                    dict_tot_Imm_doctors[key] += 1.

        lista_num_infect.append(num_I)
        lista_num_imm.append(num_Imm)

    avg_inf_drs = int(
        numpy.mean(lista_num_infect))  # i find out the average num I
    print "I", numpy.mean(lista_num_infect), numpy.mean(
        lista_num_infect) / num_Drs, avg_inf_drs, numpy.std(lista_num_infect)

    if numpy.mean(lista_num_infect
                  ) - avg_inf_drs >= 0.5:  # correccion de truncamiento
        avg_inf_drs += 1.0
    #  print avg_inf_drs

    avg_imm_drs = int(
        numpy.mean(lista_num_imm))  # i find out the average num Immune
    print "Imm", numpy.mean(lista_num_imm), numpy.mean(
        lista_num_imm) / num_Drs, avg_imm_drs, numpy.std(lista_num_imm)

    if numpy.mean(
            lista_num_imm) - avg_imm_drs >= 0.5:  # correccion de truncamiento
        avg_imm_drs += 1.0
    # print avg_imm_drs

# i sort the list from more frequently infected to less
    list_sorted_dict = sorted(dict_tot_I_doctors.iteritems(),
                              key=operator.itemgetter(1))

    new_list_sorted_dict = list_sorted_dict
    new_list_sorted_dict.reverse()

    print "I:", new_list_sorted_dict

    # i sort the list from more frequently imm to less
    list_sorted_dict_imm = sorted(dict_tot_Imm_doctors.iteritems(),
                                  key=operator.itemgetter(1))

    new_list_sorted_dict_imm = list_sorted_dict_imm
    new_list_sorted_dict_imm.reverse()

    print "Immunes:", new_list_sorted_dict_imm

    #   raw_input()

    #list_sorted_dict=[(u'Weiss', 5.0), (u'Wunderink', 5.0), (u'Keller', 4.0), (u'Go', 3.0), (u'Cuttica', 3.0), (u'Rosario', 2.0), (u'Radigan', 2.0), (u'Smith', 2.0), (u'RosenbergN', 2.0), (u'Gillespie', 1.0), (u'Osher', 1.0), (u'Mutlu', 1.0), (u'Dematte', 1.0), (u'Hawkins', 1.0), (u'Gates', 1.0)]

    lista_avg_I_drs = [
    ]  # i create the list of Drs that on average are most likely infected by the cutting day

    i = 1
    for item in new_list_sorted_dict:
        if (item[0] not in lista_avg_I_drs) and (i <= avg_inf_drs):

            lista_avg_I_drs.append(item[0])
            i += 1

    print lista_avg_I_drs, len(lista_avg_I_drs), float(
        len(lista_avg_I_drs)) / num_Drs

    lista_avg_Imm_drs = [
    ]  # i create the list of Drs that on average are most likely immune by the cutting day

    i = 1
    for item in new_list_sorted_dict_imm:
        if (item[0] not in lista_avg_Imm_drs) and (i <= avg_imm_drs) and (
                item[0] not in lista_avg_I_drs):

            lista_avg_Imm_drs.append(item[0])
            i += 1

    print lista_avg_Imm_drs, len(lista_avg_Imm_drs), float(
        len(lista_avg_Imm_drs)) / num_Drs

    # raw_input()
    for iter in range(Niter_testing):

        # i establish the initial conditions (as the average of the cutting point)

        list_I = []  #list infected doctors
        list_Immune = []
        for node in G.nodes():
            if G.node[node]['type'] != "shift":
                label = G.node[node]['label']
                G.node[node]["status"] = "S"  #by default, all are susceptible

                if label in lista_avg_I_drs:
                    G.node[node]["status"] = "I"
                    list_I.append(label)
                elif label in lista_avg_Imm_drs:
                    G.node[node]["status"] = "Immune"
                    list_Immune.append(label)
                if label in lista_avg_I_drs and label in lista_avg_Imm_drs:

                    print label, "is in the top most infected AND immune!"
                    raw_input()

        print "# I at the beginning of the testing fase:", len(list_I), float(
            len(list_I)) / num_Drs, " and # Immune:", len(list_Immune), float(
                len(list_Immune)) / num_Drs

        # print "     iter:",iter, len(list_I)

        list_single_t_evolution = []
        list_single_t_evolution.append(len(list_I))

        t = cutting_day
        while t <= max_order:  # loop over shifts, in order   just until cutting day (training segment)
            for n in G.nodes():
                if G.node[n]['type'] == "shift" and G.node[n]['order'] == t:
                    flag_possible_infection = 0
                    for doctor in G.neighbors(
                            n
                    ):  #first i check if any doctor is infected in this shift
                        if G.node[doctor]["status"] == "I":
                            flag_possible_infection = 1

                    if flag_possible_infection:
                        for doctor in G.neighbors(
                                n
                        ):  # then the doctors in that shift, gets infected with prob_infection
                            if G.node[doctor]["status"] == "S":
                                rand = random.random()
                                if rand < prob_infection:
                                    G.node[doctor]["status"] = "I"
                                    list_I.append(G.node[doctor]["label"])

            list_single_t_evolution.append(float(len(list_I)))
            #         print t, len(list_I)
            t += 1

        list_lists_t_evolutions.append(list_single_t_evolution)

        list_I = []
        list_Immune = []
        for node in G.nodes():
            if G.node[node]['type'] != "shift":
                label = G.node[node]['label']

                if G.node[node]["status"] == "I":
                    list_I.append(label)
                elif G.node[node]["status"] == "Immune":
                    list_Immune.append(label)

        print "  # I at the END of the testing fase:", len(list_I), float(
            len(list_I)) / num_Drs, " and # Immune:", len(list_Immune), float(
                len(list_Immune)) / num_Drs, "\n"

        list_dist_fixed_parameters.append(
            compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                list_actual_evol_testing, list_single_t_evolution))

        # print  " dist:",list_dist_fixed_parameters[-1]

        list_dist_abs_at_ending_point_fixed_parameters.append(
            abs(list_single_t_evolution[-1] - list_actual_evol_testing[-1])
        )  # i save the distance at the ending point between the current simu and actual evol

        list_dist_at_ending_point_fixed_parameters.append(
            list_single_t_evolution[-1] - list_actual_evol_testing[-1]
        )  # i save the distance at the ending point between the current simu and actual evol

    ############### end loop Niter  for the testing

    num_valid_endings = 0.
    for item in list_dist_abs_at_ending_point_fixed_parameters:
        if item <= delta_end:  # i count how many realizations i get close enough at the ending point
            num_valid_endings += 1.

    print "average distance of the optimum in the testing segment:", numpy.mean(
        list_dist_fixed_parameters), numpy.std(
            list_dist_fixed_parameters), list_dist_fixed_parameters
    print "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter_testing, list_dist_abs_at_ending_point_fixed_parameters

    histograma_gral_negv_posit.histograma(
        list_dist_at_ending_point_fixed_parameters,
        "../Results/histogr_raw_distances_ending_test_train_infection_p" +
        str(prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" +
        str(Niter_training) + "iter_avg_ic_day" + str(cutting_day) + ".dat")

    output_file8 = "../Results/List_tot_distances_training_segment_infection_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_training) + "iter_avg_ic_day" + str(cutting_day) + ".dat"
    file8 = open(output_file8, 'wt')

    for item in list_dist_fixed_parameters:
        print >> file8, item
    file8.close()

    output_file9 = "../Results/List_distances_ending_training_segment_infection_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_training) + "iter_avg_ic_day" + str(cutting_day) + ".dat"
    file9 = open(output_file9, 'wt')

    for item in list_dist_abs_at_ending_point_fixed_parameters:
        print >> file9, item
    file9.close()

    output_file5 = dir + "Average_time_evolution_Infection_testing_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_testing) + "iter_2012_avg_ic_day" + str(cutting_day) + ".dat"

    file5 = open(output_file5, 'wt')
    for s in range(len(list_single_t_evolution)):
        list_fixed_t = []
        for iter in range(Niter_testing):
            list_fixed_t.append(list_lists_t_evolutions[iter][s])
        print >> file5, s + cutting_day, numpy.mean(list_fixed_t)
    #  print  s+cutting_day,numpy.mean(list_fixed_t)
    file5.close()

    print "written training segment file:", optimum_filename
    print "written testing segment file:", output_file5

    print "printed out landscape file:", output_file3

    output_file10 = "../Results/Summary_results_training_segment_infection_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_training) + "iter_avg_ic_day" + str(cutting_day) + ".dat"
    file10 = open(output_file10, 'wt')

    print >> file10, "Summary results from train-testing persuasion with", Niter_training, Niter_testing, "iter (respectively), using all the individual cutting points as IC, and with values for the parameters:  prob_inf ", prob_infection, " prob immune: ", prob_Immune, "\n"

    print >> file10, "average distance of the optimum in the testing segment:", numpy.mean(
        list_dist_fixed_parameters), numpy.std(
            list_dist_fixed_parameters), list_dist_fixed_parameters, "\n"
    print >> file10, "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter_testing, list_dist_abs_at_ending_point_fixed_parameters, "\n"

    print >> file10, "written training segment file:", optimum_filename
    print >> file10, "written testing segment file:", output_file5

    file10.close()
예제 #6
0
def main(graph_name):
 

   G = nx.read_gml(graph_name)
 
   list_id_weekends_T3=look_for_T3_weekends(G)  # T3 doesnt share fellows in the weekend  (but they are the exception)


   cutting_day=243     # to separate   training-testing



   Niter=1000

   delta_end=3  # >= than + or -  dr difference at the end of the evolution

   dir_real_data='../Results/'
   dir="../Results/weight_shifts/persuasion/"  


  
   Nbins=20   # for the histogram of sum of distances






######################################################################################
#  I read the file of the actual evolution of the idea spreading in the hospital:   ##
######################################################################################



  
   filename_actual_evol="../Data/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
  


   file1=open(filename_actual_evol,'r')         ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
   list_lines_file=file1.readlines()
            

   list_actual_evol=[]  
   for line in list_lines_file:      # [1:]:   # i exclude the first row   
     
      num_adopters= float(line.split("\t")[1])          
      list_actual_evol.append(num_adopters)

   list_actual_evol_training=list_actual_evol[:cutting_day]

##################################################################


#../Results/network_final_schedule_withTeam3/Time_evolutions_Persuasion_alpha0.2_damping0.0_mutual_encourg0.7_threshold0.4_unif_distr_50iter_2012_seed31Oct_finalnetwork.dat

 
   alpha_F_min=0.100   #   # alpha=0: nobody changes their mind
   alpha_F_max=0.1001    
   delta_alpha_F=0.10    #AVOID 1.0 OR THE DYNAMICS GETS TOTALLY STUCK AND IT IS NOT ABLE TO PREDICT SHIT!
   

   min_damping=0.000   #0.0     #its harder to go back from YES to NO again. =1 means no effect, =0.5 half the movement from Y->N than the other way around, =0 never go back from Y to N
   max_damping=0.0001    #0.451
   delta_damping=0.10  
      

   min_mutual_encouragement=0.300   #  # when two Adopters meet, they convince each other even more
   max_mutual_encouragement=0.301   
   delta_mutual_encouragement=0.10
   
   
   threshold_min=0.500   #  # larger than, to be an Adopter
   threshold_max=0.501 
   delta_threshold=0.10   # AVOID 1.0 OR THE DYNAMICS GETS TOTALLY STUCK AND IT IS NOT ABLE TO PREDICT SHIT
 
   fixed_param="FIXED_threshold0.5_damping0_"    # or ""  # for the Results file that contains the sorted list of best parameters


   print_landscape="NO"#NO"  # for the whole exploration

   print_training_evol= "YES"#"#YES"   # once i know the best fit for the training segment, i run it again to get the curve









   if print_landscape =="YES":
      
      output_file3="../Results/weight_shifts/Landscape_parameters_persuasion_train_"+fixed_param+str(Niter)+"iter_Att_only_middle_day"+str(cutting_day)+".dat"  
      file3 = open(output_file3,'wt')        
      file3.close()

 
   
   
   print "\n\nPersuasion process on network, with Niter:",Niter
   
   
   dict_filenames_tot_distance={}   # i will save the filename as key and the tot distance from that curve to the original one
   dict_filenames_prod_distances={}   


  

   threshold=threshold_min
   while   threshold<= threshold_max:
      print   "thershold:",threshold

      alpha_F=alpha_F_min
      while alpha_F<= alpha_F_max:            # i explore all the parameter space, and create a file per each set of values
        alpha_A=1.0*alpha_F
        print "  alpha_F:",alpha_F

        mutual_encouragement=min_mutual_encouragement  
        while  mutual_encouragement <= max_mutual_encouragement:
          print "    mutual_encouragement:",mutual_encouragement

          damping=min_damping
          while   damping <= max_damping:
            print "      damping:",damping


         
#            dir="../Results/weight_shifts/persuasion/alpha%.2f_damping%.2f/"  % (alpha_F, damping )
           
            output_file=dir+"Time_evolutions_Persuasion_training_alpha"+str(alpha_F)+"_damping"+str(damping)+"_mutual_encourg"+str(mutual_encouragement)+"_threshold"+str(threshold)+"_"+str(Niter)+"iter_"+str(cutting_day)+"_Att_only_middle.dat"  



            output_file4=dir+"List_adopters_fellows_descending_frequency_persuasion_training_alpha"+str(alpha_F)+"_damping"+str(damping)+"_mutual_encourg"+str(mutual_encouragement)+"_threshold"+str(threshold)+"_"+str(Niter)+"iter_"+str(cutting_day)+"_Att_only_middle.dat"  


            num_Att_adopters=0.
            num_F_adopters=0.
            dict_att_freq_adoption_end={}   # to keep track of what fellow is an adopter at the end (to use along with the real ic)
            dict_fellow_freq_adoption_end={}   # to keep track of what fellow is an adopter at the end (to use along with the real ic)
            for n in G.nodes():              
               doctor=G.node[n]["label"]       
               if G.node[n]['type'] =="F":                      
                  dict_fellow_freq_adoption_end[doctor]=0.
               elif G.node[n]['type'] =="A":                      
                  dict_att_freq_adoption_end[doctor]=0.



            time_evol_number_adopters_ITER=[]  # list of complete single realizations of the dynamics
            list_dist_fixed_parameters=[]
            list_dist_at_ending_point_fixed_parameters=[]
            list_dist_abs_at_ending_point_fixed_parameters=[]

           
            list_networks_at_cutting_day=[]

            list_final_num_adopt=[]


            for iter in range(Niter):

               # print "         ",iter
              
           
                time_evol_number_adopters=[]   # for a single realization of the dynamics               

                num_adopters , seed_shift ,max_shift= set_ic(G,threshold)   # i establish who is Adopter and NonAdopter initially, and count how many shifts i have total

                time_evol_number_adopters.append(float(num_adopters))               
               

                old_num_adopters=num_adopters

                
               ########### the dynamics starts:                 
             
                shift_length=5    #i know the first shift (order 0) is of length 5

                t=0   
                while t< cutting_day:  # loop over shifts, in chronological order  (the order is the day index since seeding_day) 
                                             
                    for n in G.nodes():
                        if G.node[n]['type']=="shift" and G.node[n]['order']==t:  # i look for the shift corresponding to that time step                      (not all t's exists as 'orders' in the network!! just the days corresponding to the beginning of each shift)

                            shift_length=int(G.node[n]['shift_length'])
                            effective_shift_length=shift_length

                            if shift_length==2 and n not in list_id_weekends_T3:
                               effective_shift_length=1   # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)



                            flag_possible_persuasion=0
                            for doctor in G.neighbors(n):                               
                                if G.node[doctor]["status"]=="Adopter":   #first i check if any doctor is an adopter in this shift         
                                    flag_possible_persuasion=1                               
                                    break

                            if flag_possible_persuasion==1:
                                list_doctors=[]
                                for doctor in G.neighbors(n):   # for all drs in that shift
                                    list_doctors.append(doctor)
                                
                                
                                pairs=itertools.combinations(list_doctors,2)    # cos the shift can be 2 but also 3 doctors 
                                for pair in pairs:
                                    doctor1=pair[0]
                                    doctor2=pair[1]
                                                                                        
                                    if G.node[doctor1]['status'] != G.node[doctor2]['status']:  # if they think differently, 
                                                                                              # there will be persuasion
                                        persuasion(G,damping,doctor1,doctor2,alpha_A,alpha_F,threshold,effective_shift_length)   # i move their values of opinion 
                                        update_opinions(G,threshold,doctor1,doctor2) #  i update status and make sure the values of the vectors stay between [0,1] 
                                  
                                    else:  # if two Adopters meet, they encourage each other (if two NonAdopters, nothing happens)
                                   
                                       mutual_reinforcement(G,mutual_encouragement,doctor1,doctor2,shift_length)
                                                                 
                    list_ALL_Adopters=[]       
                    list_Adopters=[]        
                    for n in G.nodes():              
                       try:
                          if  G.node[n]["status"]=="Adopter":                                                    
                             if G.node[n]["label"] not in list_Adopters and G.node[n]["type"]=="A":
                                list_Adopters.append(G.node[n]["label"])
                             list_ALL_Adopters.append(G.node[n]["label"])

                       except: pass  # if the node is a shift, it doesnt have a 'status' attribute                   
                    new_num_adopters=len(list_Adopters)


                    if  shift_length==5: # i estimate that adoption happens in the middle of the shift
                       if t+5 < cutting_day:
                          time_evol_number_adopters.append(old_num_adopters) 
                       if t+4 < cutting_day:
                          time_evol_number_adopters.append(old_num_adopters) 
                       if t+3 < cutting_day:
                          time_evol_number_adopters.append(new_num_adopters)
                       if t+2 < cutting_day:
                          time_evol_number_adopters.append(new_num_adopters)
                       if t+1 < cutting_day:
                          time_evol_number_adopters.append(new_num_adopters)
                       t+=5
                      
        
                    elif  shift_length==4:
                        if t+4 < cutting_day:
                           time_evol_number_adopters.append(old_num_adopters)                     
                        if t+3 < cutting_day:
                           time_evol_number_adopters.append(old_num_adopters) 

                        if t+2 < cutting_day:
                           time_evol_number_adopters.append(new_num_adopters)                       
                       
                        if t+1 < cutting_day:
                           time_evol_number_adopters.append(new_num_adopters)
                        t+=4
                     
 
                    elif  shift_length==3:
                        if t+3 < cutting_day:
                           time_evol_number_adopters.append(old_num_adopters)                     
                       
                        if t+2 < cutting_day:
                           time_evol_number_adopters.append(new_num_adopters)
                       
                        if t+1 < cutting_day:
                           time_evol_number_adopters.append(new_num_adopters)
                       
                        t+=3
                      


                    elif  shift_length==2:
                        if t+2 < cutting_day:
                           time_evol_number_adopters.append(old_num_adopters)                     
                       
                        if t+1 < cutting_day:
                           time_evol_number_adopters.append(new_num_adopters)
                       
                      
                        t+=2
                      

                    elif  shift_length==1:                      
                        if t+1 < cutting_day:
                           time_evol_number_adopters.append(new_num_adopters)                       
                       
                        t+=1
                      

                    old_num_adopters=new_num_adopters

                ############## end while loop over t
               

               
               
                time_evol_number_adopters_ITER.append(time_evol_number_adopters)


                list_final_num_adopt.append(time_evol_number_adopters[-1])

               
                list_dist_fixed_parameters.append(compare_real_evol_vs_simus_to_be_called.compare_two_curves( list_actual_evol_training,time_evol_number_adopters))
               
                list_dist_abs_at_ending_point_fixed_parameters.append( abs(time_evol_number_adopters[-1]-list_actual_evol_training[-1]) )

                list_dist_at_ending_point_fixed_parameters.append( time_evol_number_adopters[-1]-list_actual_evol_training[-1]) 


                
                for n in G.nodes():              
                    doctor= G.node[n]["label"]  
                    if G.node[n]['type'] != "shift":
                      if  G.node[n]['status'] =="Adopter":                                    
                         if G.node[n]['type'] =="F":                                                                                              
                            dict_fellow_freq_adoption_end[doctor]   += 1.  
                            num_F_adopters+=1.
                         elif G.node[n]['type'] =="A":                                                                                              
                            dict_att_freq_adoption_end[doctor]   += 1.                        
                            num_Att_adopters+=1.

            #######################   end loop Niter for the training fase


            list_pair_dist_std_delta_end=[]
        
            list_pair_dist_std_delta_end.append(numpy.mean(list_dist_fixed_parameters) )   # average dist between the curves over Niter
            list_pair_dist_std_delta_end.append(numpy.std(list_dist_fixed_parameters) )

            list_pair_dist_std_delta_end.append(numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

         

                     
            value=numpy.mean(list_dist_fixed_parameters) *numpy.mean(list_dist_abs_at_ending_point_fixed_parameters) # if SD=0, it is a problem, because then that is the minimun value, but not the optimum i am looking for!!
        
            dict_filenames_prod_distances[output_file]=  value                  


            if (numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)) <= delta_end:  # i only consider situations close enough at the ending point   
               dict_filenames_tot_distance[output_file]=list_pair_dist_std_delta_end 
  
          
            if print_landscape =="YES":
               file3 = open(output_file3,'at')          # i print out the landscape           
               print >> file3, alpha_F, damping, mutual_encouragement, threshold,numpy.mean(list_dist_abs_at_ending_point_fixed_parameters), numpy.mean(list_dist_fixed_parameters),  numpy.mean(list_final_num_adopt),numpy.std(list_final_num_adopt),  numpy.std(list_final_num_adopt)/numpy.mean(list_final_num_adopt)
               file3.close()



            if print_training_evol=="YES":
               file = open(output_file,'wt')        
               for i in range(len(time_evol_number_adopters)):  #time step by time step
                  list_fixed_t=[]
                  for iteracion in range (Niter): #loop over all independent iter of the process
                     list_fixed_t.append(time_evol_number_adopters_ITER[iteracion][i])  # i collect all values for the same t, different iter  

                  print >> file, i,numpy.mean(list_fixed_t),numpy.std(list_fixed_t), alpha_F,damping,mutual_encouragement       
                  last_adoption_value=numpy.mean(list_fixed_t)
               file.close()
               print "written evolution file:", output_file
           

               print  "\nFraction of times each fellow was an adopter at the end of the training segment:"
               for n in G.nodes():              
                  if G.node[n]['type'] =="F":   
                     doctor= G.node[n]["label"]    
                     dict_fellow_freq_adoption_end[doctor]= dict_fellow_freq_adoption_end[doctor]/float(Niter)         
                     print doctor,"\t", dict_fellow_freq_adoption_end[doctor]
             
               print "(out of",len(dict_fellow_freq_adoption_end),"fellows)\n"
               sorted_list_tuples=sorted(dict_fellow_freq_adoption_end.iteritems(), key=operator.itemgetter(1),reverse=True)
             

               file4 = open(output_file4,'wt')
               print >> file4,last_adoption_value, "(value adoption among Att at cutting day)","Avg # F adopters",num_F_adopters/Niter, "Avg # A adopters",num_Att_adopters/Niter
               for pair in sorted_list_tuples:
                  print >> file4, pair[0], pair[1]
               file4.close()
               print "written adoption frecuency file for fellows:", output_file4


            damping += delta_damping
          mutual_encouragement += delta_mutual_encouragement
        alpha_F += delta_alpha_F
      threshold  += delta_threshold
    


   string_name="persuasion_training_"+fixed_param+str(Niter)+"iter_"+str(cutting_day)+"_Att_only_middle.dat"    # for the "Results" file with the sorted list of files
   list_order_dict=  compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(dict_filenames_tot_distance,string_name,Niter,cutting_day)


  
   
   list_order_dict2= compare_real_evol_vs_simus_to_be_called.pick_minimum_prod_distances(dict_filenames_prod_distances,string_name,Niter,cutting_day)

  



  
   if print_landscape =="YES":
      print "printed out landscape file:",output_file3


   print "\n\n"
def main(graph_name):

    G = nx.read_gml(graph_name)

    list_id_weekends_T3 = look_for_T3_weekends(
        G
    )  # T3 doesnt share fellows in the weekend  (but they are the exception)

    percent_envelope = 95.
    Niter = 1000

    cutting_day = 125

    Nbins = 200  # for the histogram of sum of distances

    for_testing_fixed_set = "YES"  # when YES, fixed values param and get all statistics on final distances etc

    envelopes = "NO"

    delta_end = 3.  # >= than + or -  dr difference at the end of the evolution

    dir_real_data = '../Results/'

    all_team = "NO"  # as adopters or not  NO now means i use the file without fellows, only attendings

    if for_testing_fixed_set == "NO":
        output_file3 = "../Results/weight_shifts/Landscape_parameters_persuasion_" + str(
            Niter) + "iter_A_F_inferred.dat"
        file3 = open(output_file3, 'wt')
        file3.close()

######################################################################################
#  I read the file of the actual evolution of the idea spreading in the hospital:   ##
######################################################################################

    if all_team == "YES":
        print "remember that now i use the file of adopters without fellows\n../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
        exit()

    else:
        filename_actual_evol = "../Results/Actual_evolution_adopters_from_inference.dat"

    file1 = open(
        filename_actual_evol, 'r'
    )  ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
    list_lines_file = file1.readlines()

    list_actual_evol = []
    for line in list_lines_file:  # [1:]:   # i exclude the first row

        num_adopters = float(line.split("\t")[1])
        list_actual_evol.append(num_adopters)

##################################################################

#../Results/weight_shifts/persuasion/Time_evolutions_Persuasion_training_alpha0.2_damping0.0_mutual_encourg0.5_threshold0.7_unif_distr_1000iter_2012_seed31Oct_finalnetwork_day125.dat

#../Results/weight_shifts/persuasion/Time_evolutions_Persuasion_training_alpha0.5_damping0.4_mutual_encourg0.5_threshold0.5_unif_distr_1000iter_2012_seed31Oct_finalnetwork_day125.dat
#OJO!!! NECESITO DOS DECIMALES SIEMPRE, PARA QUE CUADRE CON EL NOMBRE DE LOS SUB-DIRECTORIOS DONDE LO GUARDO

    alpha_F_min = 0.10  #0.15   # alpha=0: nobody changes their mind
    alpha_F_max = 0.101  #0.351
    delta_alpha_F = 0.10  #AVOID 1.0 OR THE DYNAMICS GETS TOTALLY STUCK AND IT IS NOT ABLE TO PREDICT SHIT!

    min_damping = 0.00  #0.0     #its harder to go back from YES to NO again. =1 means no effect, =0.5 half the movement from Y->N than the other way around, =0 never go back from Y to N
    max_damping = 0.001  #0.451
    delta_damping = 0.10

    min_mutual_encouragement = 0.000  #0.50  # when two Adopters meet, they convince each other even more
    max_mutual_encouragement = 0.001  # 0.51   # KEEP THIS FIXED VALUES FOR NOW
    delta_mutual_encouragement = 0.10

    threshold_min = 0.50  #0.50  # larger than, to be an Adopte
    threshold_max = 0.501  # 0.51    # KEEP THIS FIXED VALUES FOR NOW
    delta_threshold = 0.10  # AVOID 1.0 OR THE DYNAMICS GETS TOTALLY STUCK AND IT IS NOT ABLE TO PREDICT SHIT

    print "\n\nPersuasion process on network, with Niter:", Niter

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    threshold = threshold_min
    while threshold <= threshold_max:
        print "thershold:", threshold

        alpha_F = alpha_F_min
        while alpha_F <= alpha_F_max:  # i explore all the parameter space, and create a file per each set of valuesllkl
            alpha_A = 1.0 * alpha_F
            print "  alpha_F:", alpha_F

            mutual_encouragement = min_mutual_encouragement
            while mutual_encouragement <= max_mutual_encouragement:
                print "    mutual_encouragement:", mutual_encouragement

                damping = min_damping
                while damping <= max_damping:
                    print "      damping:", damping

                    dir = "../Results/weight_shifts/persuasion/alpha%.2f_damping%.2f/" % (
                        alpha_F, damping)

                    if for_testing_fixed_set == "YES":
                        output_file = dir + "Time_evol_Persuasion_alpha" + str(
                            alpha_F
                        ) + "_damping" + str(damping) + "_mutual" + str(
                            mutual_encouragement
                        ) + "_threshold" + str(threshold) + "_" + str(
                            Niter) + "iter_alphaA_eq_alphaF_A_F_inferred.dat"

                    else:
                        output_file = dir + "Time_evol_Persuasion_alpha" + str(
                            alpha_F
                        ) + "_damping" + str(damping) + "_mutual" + str(
                            mutual_encouragement
                        ) + "_threshold" + str(threshold) + "_" + str(
                            Niter) + "iter_alphaA_eq_alphaF_A_F_inferred.dat"

                    file = open(output_file, 'wt')
                    file.close()

                    time_evol_number_adopters_ITER = [
                    ]  # list of complete single realizations of the dynamics
                    list_dist_fixed_parameters = []
                    list_dist_fixed_parameters_testing_segment = []
                    list_dist_abs_at_ending_point_fixed_parameters = []
                    list_dist_at_ending_point_fixed_parameters = []
                    list_final_num_adopt = []
                    list_abs_dist_point_by_point_indiv_simus_to_actual = []
                    list_dist_point_by_point_indiv_simus_to_actual = []

                    #list_abs_dist_at_cutting_day=[]
                    for iter in range(Niter):

                        print "         ", iter
                        list_t = []

                        time_evol_number_adopters = [
                        ]  # for a single realization of the dynamics

                        num_adopters, seed_shift, max_shift = set_ic(
                            G, threshold
                        )  # i establish who is Adopter and NonAdopter initially, and count how many shifts i have total

                        time_evol_number_adopters.append(float(num_adopters))
                        # print "initial number of adopters:", num_adopters
                        list_t.append(0)

                        ########OJO~!!!!!!!!!! COMENTAR ESTO CUANDO ESTOY BARRIENDO TOOOOOOOOOODO EL ESPACIO DE PARAMETROS
                        #                file4 = open(output_file.split('.dat')[0]+"_indiv_iter"+str(iter)+".dat",'wt')
                        #               file4.close()
                        ##########################################

                        # the dynamics starts:
                        t = int(seed_shift
                                ) + 1  # the first time step is just IC.???

                        while t <= max_shift:  # loop over shifts, in chronological order  (the order is the day index since seeding_day)
                            # print 't:',t
                            list_t.append(t)
                            for n in G.nodes():
                                if G.node[n]['type'] == "shift" and G.node[n][
                                        'order'] == t:  # i look for the shift corresponding to that time step

                                    shift_length = int(
                                        G.node[n]['shift_length'])

                                    if shift_length == 2 and n not in list_id_weekends_T3:
                                        shift_length = 1  # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)

#    print "one-day weekend", G.node[n]['label'],G.node[n]['shift_length']

                                    flag_possible_persuasion = 0
                                    for doctor in G.neighbors(n):
                                        if G.node[doctor][
                                                "status"] == "Adopter":  #first i check if any doctor is an adopter in this shift
                                            flag_possible_persuasion = 1
                                            break

                                    if flag_possible_persuasion == 1:
                                        list_doctors = []
                                        for doctor in G.neighbors(
                                                n
                                        ):  # for all drs in that shift
                                            list_doctors.append(doctor)

                                        pairs = itertools.combinations(
                                            list_doctors, 2
                                        )  # cos the shift can be 2 but also 3 doctors
                                        for pair in pairs:
                                            doctor1 = pair[0]
                                            doctor2 = pair[1]

                                            if G.node[doctor1][
                                                    'status'] != G.node[doctor2][
                                                        'status']:  # if they think differently,
                                                # there will be persuasion
                                                persuasion(
                                                    G, damping, doctor1,
                                                    doctor2, alpha_A, alpha_F,
                                                    threshold, shift_length
                                                )  # i move their values of opinion
                                                update_opinions(
                                                    G, threshold, doctor1,
                                                    doctor2
                                                )  #  i update status and make sure the values of the vectors stay between [0,1]

                                            else:  # if two Adopters meet, they encourage each other (if two NonAdopters, nothing happens)

                                                mutual_reinforcement(
                                                    G, mutual_encouragement,
                                                    doctor1, doctor2,
                                                    shift_length)
                                # else:
                                #   print "  no persuasion possible during shift (no adopters present)!"

                            list_Adopters = [
                            ]  #count how many i have at this time
                            for n in G.nodes():
                                try:
                                    if G.node[n]["status"] == "Adopter":
                                        if G.node[n][
                                                "label"] not in list_Adopters:  # and G.node[n]["type"]=="A":
                                            list_Adopters.append(
                                                G.node[n]["label"])
                                except:
                                    pass  # if the node is a shift, it doesnt have a 'status' attribute

                        #  if for_testing_fixed_set=="YES":
                        #    if t==cutting_day:
                        #      list_abs_dist_at_cutting_day.append(abs(float(list_actual_evol[-1])-float(len(list_Adopters))))
                        #     print abs(float(list_actual_evol[-1])-float(len(list_Adopters))), float(list_actual_evol[t]),float(len(list_Adopters))

                            time_evol_number_adopters.append(
                                float(len(list_Adopters)))

                            t += 1

                        ############## end while loop over t

                        time_evol_number_adopters_ITER.append(
                            time_evol_number_adopters)

                        list_dist_fixed_parameters.append(
                            compare_real_evol_vs_simus_to_be_called.
                            compare_two_curves(list_actual_evol,
                                               time_evol_number_adopters))
                        list_dist_fixed_parameters_testing_segment.append(
                            compare_real_evol_vs_simus_to_be_called.
                            compare_two_curves_testing_segment(
                                list_actual_evol, time_evol_number_adopters,
                                cutting_day))

                        list_dist_abs_at_ending_point_fixed_parameters.append(
                            abs(time_evol_number_adopters[-1] -
                                list_actual_evol[-1]))
                        list_dist_at_ending_point_fixed_parameters.append(
                            time_evol_number_adopters[-1] -
                            list_actual_evol[-1])

                        list_final_num_adopt.append(
                            time_evol_number_adopters[-1])

                        ########OJO~!!!!!!!!!! COMENTAR ESTO CUANDO ESTOY BARRIENDO TOOOOOOOOOODO EL ESPACIO DE PARAMETROS
                        #  file4 = open(output_file.split('.dat')[0]+"_indiv_iter"+str(iter)+".dat",'at')
                        # for i in range(len(time_evol_number_adopters)):  #ime step by time step
                        #   print >> file4, i,time_evol_number_adopters[i], alpha_F,damping,mutual_encouragement
                        #file4.close()
                        ########################################################

                        for index in range(len(time_evol_number_adopters)):

                            list_abs_dist_point_by_point_indiv_simus_to_actual.append(
                                abs(time_evol_number_adopters[index] -
                                    list_actual_evol[index]))
                            list_dist_point_by_point_indiv_simus_to_actual.append(
                                time_evol_number_adopters[index] -
                                list_actual_evol[index])

                    #######################end loop over Niter

                    list_pair_dist_std_delta_end = []

                    list_pair_dist_std_delta_end.append(
                        numpy.mean(list_dist_fixed_parameters)
                    )  # average dist between the curves over Niter
                    list_pair_dist_std_delta_end.append(
                        numpy.std(list_dist_fixed_parameters))

                    list_pair_dist_std_delta_end.append(
                        numpy.mean(
                            list_dist_abs_at_ending_point_fixed_parameters))

                    if for_testing_fixed_set == "NO":
                        file3 = open(output_file3,
                                     'at')  # i print out the landscape
                        print >> file3, alpha_F, damping, mutual_encouragement, threshold, numpy.mean(
                            list_dist_abs_at_ending_point_fixed_parameters
                        ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                            list_final_num_adopt), numpy.std(
                                list_final_num_adopt
                            ), numpy.std(list_final_num_adopt) / numpy.mean(
                                list_final_num_adopt)
                        file3.close()

                    if (
                            numpy.mean(
                                list_dist_abs_at_ending_point_fixed_parameters)
                    ) <= delta_end:  # i only consider situations close enough at the ending point

                        dict_filenames_tot_distance[
                            output_file] = list_pair_dist_std_delta_end

                    file = open(output_file, 'wt')
                    for i in range(len(time_evol_number_adopters)
                                   ):  #time step by time step
                        list_fixed_t = []
                        for iteracion in range(
                                Niter
                        ):  #loop over all independent iter of the process
                            list_fixed_t.append(
                                time_evol_number_adopters_ITER[iteracion][i]
                            )  # i collect all values for the same t, different iter

                        print >> file, list_t[i], numpy.mean(
                            list_fixed_t), numpy.std(
                                list_fixed_t
                            ), alpha_F, damping, mutual_encouragement
                    file.close()

                    print "printed out:  ", output_file

                    if envelopes == "YES":
                        calculate_envelope_set_curves.calculate_envelope(
                            time_evol_number_adopters_ITER, percent_envelope,
                            "Persuasion", [
                                alpha_F, damping, mutual_encouragement,
                                threshold
                            ])

                    if for_testing_fixed_set == "YES":

                        num_valid_endings = 0.
                        for item in list_dist_abs_at_ending_point_fixed_parameters:
                            if item <= delta_end:  # i count how many realizations i get close enough at the ending point
                                num_valid_endings += 1.

                        print "average distance of the optimum in the testing segment:", numpy.mean(
                            list_dist_fixed_parameters), numpy.std(
                                list_dist_fixed_parameters
                            ), list_dist_fixed_parameters, "\n"
                        print "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter, "mean ending dist:", numpy.mean(
                            list_dist_at_ending_point_fixed_parameters
                        ), "SD final dist", numpy.std(
                            list_dist_at_ending_point_fixed_parameters
                        ), list_dist_at_ending_point_fixed_parameters

                        histogram_filename = "../Results/weight_shifts/histogr_raw_distances_ending_persuasion_alpha" + str(
                            alpha_F) + "_damping" + str(
                                damping) + "_mutual_encourg" + str(
                                    mutual_encouragement
                                ) + "_threshold" + str(threshold) + "_" + str(
                                    Niter) + "iter_alphaA_eq_alphaF_day" + str(
                                        cutting_day) + "_A_F_inferred.dat"
                        histograma_gral_negv_posit.histograma(
                            list_dist_at_ending_point_fixed_parameters,
                            histogram_filename)

                        histogram_filename2 = "../Results/weight_shifts/histogr_sum_dist_traject_persuasion_alpha" + str(
                            alpha_F) + "_damping" + str(
                                damping) + "_mutual_encourg" + str(
                                    mutual_encouragement
                                ) + "_threshold" + str(threshold) + "_" + str(
                                    Niter) + "iter_alphaA_eq_alphaF_day" + str(
                                        cutting_day) + "_A_F_inferred.dat"

                        histograma_bines_gral.histograma_bins(
                            list_dist_fixed_parameters, Nbins,
                            histogram_filename2)

                        histogram_filename3 = "../Results/weight_shifts/histogr_sum_dist_testing_segment_persuasion_alpha" + str(
                            alpha_F) + "_damping" + str(
                                damping) + "_mutual_encourg" + str(
                                    mutual_encouragement
                                ) + "_threshold" + str(threshold) + "_" + str(
                                    Niter) + "iter_alphaA_eq_alphaF_day" + str(
                                        cutting_day) + "_A_F_inferred.dat"

                        histograma_bines_gral.histograma_bins_zero(
                            list_dist_fixed_parameters_testing_segment, Nbins,
                            histogram_filename3)

                        histogram_filename4 = "../Results/weight_shifts/histogr_abs_dist_point_by_point_persuasion_alpha" + str(
                            alpha_F) + "_damping" + str(
                                damping) + "_mutual_encourg" + str(
                                    mutual_encouragement
                                ) + "_threshold" + str(threshold) + "_" + str(
                                    Niter) + "iter_alphaA_eq_alphaF_day" + str(
                                        cutting_day) + "_A_F_inferred.dat"

                        histograma_gral_negv_posit.histograma(
                            list_abs_dist_point_by_point_indiv_simus_to_actual,
                            histogram_filename4)

                        histogram_filename5 = "../Results/weight_shifts/histogr_dist_point_by_point_persuasion_alpha" + str(
                            alpha_F) + "_damping" + str(
                                damping) + "_mutual_encourg" + str(
                                    mutual_encouragement
                                ) + "_threshold" + str(threshold) + "_" + str(
                                    Niter) + "iter_alphaA_eq_alphaF_day" + str(
                                        cutting_day) + "_A_F_inferred.dat"

                        histograma_gral_negv_posit.histograma(
                            list_dist_point_by_point_indiv_simus_to_actual,
                            histogram_filename5)

                        output_file10 = "../Results/weight_shifts/Summary_results_persuasion_alpha" + str(
                            alpha_F) + "_damping" + str(
                                damping) + "_mutual_encourg" + str(
                                    mutual_encouragement
                                ) + "_threshold" + str(threshold) + "_" + str(
                                    Niter) + "iter_alphaA_eq_alphaF_day" + str(
                                        cutting_day) + "_A_F_inferred.dat"
                        file10 = open(output_file10, 'wt')

                        print >> file10, "Summary results from best fit persuasion with", Niter, "iter, and with values for the parameters:  alpha ", alpha_F, " damping: ", damping, " mutual_encourg: ", mutual_encouragement, " threshold:", threshold

                        print >> file10, "average distance of the optimum in the testing segment:", numpy.mean(
                            list_dist_fixed_parameters), numpy.std(
                                list_dist_fixed_parameters
                            ), list_dist_fixed_parameters
                        print >> file10, "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter, "mean ending dist:", numpy.mean(
                            list_dist_at_ending_point_fixed_parameters
                        ), "SD final dist", numpy.std(
                            list_dist_at_ending_point_fixed_parameters
                        ), list_dist_at_ending_point_fixed_parameters

                        print >> file10, "written optimum train_test evolution file:", output_file
                        print >> file10, "written histogram file: ", histogram_filename
                        print >> file10, "written histogram file: ", histogram_filename2

                        file10.close()

                        print "written optimum train_test evolution file:", output_file

                        print "written summary file: ", output_file10

                    damping += delta_damping
                mutual_encouragement += delta_mutual_encouragement
            alpha_F += delta_alpha_F
        threshold += delta_threshold

    if for_testing_fixed_set == "NO":  # only if i am exploring the whole landscape, i need to call this function, otherwise, i already know the optimum
        compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
            dict_filenames_tot_distance, "Persuasion_weight", all_team, Niter,
            None)  #last argument, cutting day (it doesnt apply)

    if for_testing_fixed_set == "NO":
        print "written landscape file:", output_file3
def main(graph_name):

    G = nx.read_gml(graph_name)

    all_team = "NO"  # as adopters or not

    Niter = 100

    dir_real_data = '../Results/'

    delta_end = 3  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)
    # NO RESTRICTION, TO OBTAIN THE COMPLETE PARAMETER LANDSCAPE

    output_file3 = dir_real_data + "Landscape_parameters_infection_" + str(
        Niter) + "iter.dat"
    file3 = open(output_file3, 'wt')

    file3.close()

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    if all_team == "YES":
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_all_team_as_adopters_SIMPLER.csv"

    else:
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_SIMPLER.csv"
    #ya no necesito CAMBIAR TB EL NOMBRE DEL ARCHIVO EN EL CODIGO PARA COMPARAR CURVAs

    list_actual_evol = []
    result_actual_file = csv.reader(open(filename_actual_evol, 'rb'),
                                    delimiter=',')
    cont = 0
    for row in result_actual_file:
        if cont > 0:  # i ignore the first line with the headers

            num_adopters = row[3]

            list_actual_evol.append(float(num_adopters))

        cont += 1

##################################################################

#../Results/network_final_schedule_withTeam3/infection/Average_time_evolution_Infection_p0.9_Immune0.5_1000iter_2012.dat

    prob_min = 0.00
    prob_max = 1.001
    delta_prob = 0.01

    prob_Immune_min = 0.0
    prob_Immune_max = 1.001
    delta_prob_Immune = 0.01

    dir = "../Results/network_final_schedule_withTeam3_local/infection/"

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            output_file2 = dir + "Average_time_evolution_Infection_p" + str(
                prob_infection) + "_" + "Immune" + str(
                    prob_Immune) + "_" + str(Niter) + "iter_2012.dat"
            file2 = open(output_file2, 'wt')
            file2.close()

            # i create the empty list of list for the Niter temporal evolutions
            num_shifts = 0
            for n in G.nodes():
                G.node[n]["status"] = "S"
                if G.node[n]['type'] == "shift":
                    num_shifts += 1

        #  list_final_I_values_fixed_p=[]  # i dont care about the final values right now, but about the whole time evol
            list_lists_t_evolutions = []

            list_dist_fixed_parameters = []
            list_abs_dist_at_ending_point_fixed_parameters = []
            list_final_num_infected = []

            for iter in range(Niter):

                print "     iter:", iter

                #######OJO~!!!!!!!!!! COMENTAR ESTO CUANDO ESTOY BARRIENDO TOOOOOOOOOODO EL ESPACIO DE PARAMETROS
                #file_name_indiv_evol=output_file2.strip("Average_").split('.dat')[0]+"_indiv_iter"+str(iter)+".dat"

                #file4 = open(file_name_indiv_evol,'wt')
                #file4.close()
                ##########################################

                list_I = []  #list infected doctors
                list_ordering = []
                list_s = []

                ########### set I.C.

                max_order = 0
                for n in G.nodes():
                    G.node[n]["status"] = "S"  # all nodes are Susceptible
                    if G.node[n]['type'] == "shift":
                        list_s.append(n)
                        if G.node[n]['order'] > max_order:
                            max_order = G.node[n]['order']
                    else:
                        if G.node[n]['label'] == "Wunderink" or G.node[n][
                                "label"] == "Weiss":
                            G.node[n]["status"] = "I"
                            list_I.append(G.node[n]['label'])

                list_single_t_evolution = []
                list_single_t_evolution.append(
                    2.0)  # I always start with TWO infected doctors!!

                for n in G.nodes(
                ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                    if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                      == "F"):
                        if G.node[n]['label'] != "Wunderink" and G.node[n][
                                "label"] != "Weiss":
                            rand = random.random()
                            if rand < prob_Immune:
                                G.node[n]["status"] = "Immune"

            #   print max_order

            ################# the dynamics starts:

                t = 1
                while t <= max_order:  # loop over shifts, in order
                    for n in G.nodes():
                        if G.node[n]['type'] == "shift" and G.node[n][
                                'order'] == t:
                            flag_possible_infection = 0
                            for doctor in G.neighbors(
                                    n
                            ):  #first i check if any doctor is infected in this shift
                                if G.node[doctor]["status"] == "I":
                                    flag_possible_infection = 1

                            if flag_possible_infection:
                                for doctor in G.neighbors(
                                        n
                                ):  # then the doctors in that shift, gets infected with prob_infection
                                    if G.node[doctor]["status"] == "S":
                                        rand = random.random()
                                        if rand < prob_infection:
                                            G.node[doctor]["status"] = "I"
                                            list_I.append(
                                                G.node[doctor]["label"])

                    list_single_t_evolution.append(float(len(list_I)))

                    t += 1

                    ######## end t loop

                ########OJO~!!!!!!!!!! COMENTAR ESTO CUANDO ESTOY BARRIENDO TOOOOOOOOOODO EL ESPACIO DE PARAMETROS
                #file4 = open(file_name_indiv_evol,'at')
                #for i in range(len(list_single_t_evolution)):  #ime step by time step
                #  print >> file4, i,list_single_t_evolution[i], prob_infection, prob_Immune
                #file4.close()
                ########################################################

                list_lists_t_evolutions.append(list_single_t_evolution)

                list_dist_fixed_parameters.append(
                    compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                        list_actual_evol, list_single_t_evolution))

                list_abs_dist_at_ending_point_fixed_parameters.append(
                    abs(list_single_t_evolution[-1] - list_actual_evol[-1])
                )  # i save the distance at the ending point between the current simu and actual evol

                list_final_num_infected.append(list_single_t_evolution[-1])

            ############################# end loop Niter

            list_pair_dist_std_delta_end = []

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_fixed_parameters)
            )  # average dist between the curves over Niter
            list_pair_dist_std_delta_end.append(
                numpy.std(list_dist_fixed_parameters))

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_abs_dist_at_ending_point_fixed_parameters))

            file3 = open(output_file3, 'at')  # i print out the landscape
            print >> file3, prob_infection, prob_Immune, numpy.mean(
                list_abs_dist_at_ending_point_fixed_parameters
            ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                list_final_num_infected
            ), numpy.std(list_final_num_infected), numpy.std(
                list_final_num_infected) / numpy.mean(list_final_num_infected)
            file3.close()

            if (
                    numpy.mean(list_abs_dist_at_ending_point_fixed_parameters)
            ) <= delta_end:  # i only consider situations close enough at the ending point

                dict_filenames_tot_distance[
                    output_file2] = list_pair_dist_std_delta_end

            file2 = open(output_file2, 'at')
            for s in range(len(list_single_t_evolution)):
                list_fixed_t = []
                for iter in range(Niter):
                    list_fixed_t.append(list_lists_t_evolutions[iter][s])
                print >> file2, s, numpy.mean(list_fixed_t)
            file2.close()

            # file = open(output_file,'at')
            #print >> file,  prob_infection, numpy.mean(list_final_I_values_fixed_p)
            #file.close()

            # print list_dist_fixed_parameters

            #  histograma_bines_gral.histograma_bins(list_dist_fixed_parameters,50, "../Results/histogr_distances_indiv_infect_simus_to_the_average_curve_p"+str(prob_infection)+"_"+"Immune"+str(prob_Immune)+"_"+str(Niter)+"iter.dat")  # Nbins=100

            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

    compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
        dict_filenames_tot_distance, "Infection", all_team, Niter, None)
    # file3.close()
    print "printed out landscape file:", output_file3
def main(graph_name):

    cutting_day = 175  # to separate   training-testing

    G = nx.read_gml(graph_name)

    list_id_weekends_T3 = look_for_T3_weekends(
        G
    )  # T3 doesnt share fellows in the weekend  (but they are the exception)

    all_team = "NO"  # as adopters or not
    Nbins = 20  # for the histogram of sum of distances

    dir_real_data = '../Results/'

    dir = "../Results/weight_shifts/infection/"

    delta_end = 3.  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

    Niter_training = 1000

    fixed_param = ""  #"FIXED_Pimm0_"    # or ""  # for the Results file that contains the sorted list of best parameters

    output_file3 = "../Results/weight_shifts/Landscape_parameters_infection_train_test_" + str(
        Niter_training) + "iter.dat"
    file3 = open(output_file3, 'wt')

    file3.close()

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    if all_team == "YES":
        print "remember that now i use the file of adopters without fellows\n../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
        exit()

    else:
        filename_actual_evol = "../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"

    file1 = open(
        filename_actual_evol, 'r'
    )  ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
    list_lines_file = file1.readlines()

    list_actual_evol = []
    for line in list_lines_file:  # [1:]:   # i exclude the first row

        num_adopters = float(line.split(" ")[1])
        list_actual_evol.append(num_adopters)

    list_actual_evol_training = list_actual_evol[:cutting_day]
    #   list_actual_evol_testing=list_actual_evol[(cutting_day-1):]   #i dont use this

    ##################################################################

    #../Results/network_final_schedule_withTeam3/infection/Average_time_evolution_Infection_p0.9_Immune0.5_1000iter_2012.dat

    prob_min = 0.0
    prob_max = 1.01
    delta_prob = 0.1

    prob_Immune_min = 0.00
    prob_Immune_max = 1.01
    delta_prob_Immune = 0.1

    list_dist_at_ending_point_fixed_parameters = []
    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one
    dict_filenames_prod_distances = {}

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            output_file2 = dir + "Average_time_evolution_Infection_training_p" + str(
                prob_infection) + "_" + "Immune" + str(
                    prob_Immune) + "_" + str(
                        Niter_training) + "iter_2012_avg_ic_day" + str(
                            cutting_day) + ".dat"
            #   file2 = open(output_file2,'wt')                                          I DONT NEED TO WRITE IT, COS I WILL USE THE WHOLE FILE FROM THE WHOLE FIT, WITH THE PARAMETER VALUES THAT THE TESTING-UP-TODAY-125 TELLS ME
            #  file2.close()

            # i create the empty list of list for the Niter temporal evolutions
            num_shifts = 0
            num_Drs = 0.
            for n in G.nodes():
                G.node[n]["status"] = "S"
                if G.node[n]['type'] == "shift":
                    num_shifts += 1
                else:
                    num_Drs += 1.

        #  list_final_I_values_fixed_p=[]  # i dont care about the final values right now, but about the whole time evol
            list_lists_t_evolutions = []

            list_dist_fixed_parameters = []
            list_dist_abs_at_ending_point_fixed_parameters = []
            list_final_num_infected = []

            for iter in range(Niter_training):

                #   print "     iter:",iter

                list_I = []  #list infected doctors
                list_ordering = []
                list_s = []
                list_A = []
                list_F = []

                ########### set I.C.

                max_order = 0
                for n in G.nodes():
                    G.node[n]["status"] = "S"  # all nodes are Susceptible
                    if G.node[n]['type'] == "shift":
                        list_s.append(n)
                        if G.node[n]['order'] > max_order:
                            max_order = G.node[n]['order']
                    else:
                        if G.node[n]['label'] == "Wunderink" or G.node[n][
                                "label"] == "Weiss":
                            G.node[n]["status"] = "I"
                            list_I.append(G.node[n]['label'])

                        if G.node[n]['type'] == "A":
                            list_A.append(n)

                        if G.node[n]['type'] == "F":
                            list_F.append(n)

                list_single_t_evolution = []
                list_single_t_evolution.append(
                    2.0)  # I always start with TWO infected doctors!!

                for n in G.nodes(
                ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                    if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                      == "F"):
                        if G.node[n]['label'] != "Wunderink" and G.node[n][
                                "label"] != "Weiss":
                            rand = random.random()
                            if rand < prob_Immune:
                                G.node[n]["status"] = "Immune"

            #   print max_order

            ################# the dynamics starts:

                t = 1
                while t < cutting_day:  # loop over shifts, in order   just until cutting day (training segment)
                    for n in G.nodes():
                        if G.node[n]['type'] == "shift" and G.node[n][
                                'order'] == t:

                            shift_lenght = int(G.node[n]['shift_lenght'])

                            if shift_lenght == 2 and n not in list_id_weekends_T3:
                                shift_lenght = 1  # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)
                            #  print "one-day weekend", G.node[n]['label'],G.node[n]['shift_lenght']

                            flag_possible_infection = 0
                            for doctor in G.neighbors(
                                    n
                            ):  #first i check if any doctor is infected in this shift
                                if G.node[doctor]["status"] == "I":
                                    flag_possible_infection = 1

                            if flag_possible_infection:
                                for doctor in G.neighbors(
                                        n
                                ):  # then the doctors in that shift, gets infected with prob_infection
                                    for i in range(shift_lenght):
                                        if G.node[doctor]["status"] == "S":
                                            rand = random.random()
                                            if rand < prob_infection:
                                                G.node[doctor]["status"] = "I"
                                                if G.node[doctor][
                                                        "type"] == "A":
                                                    list_I.append(
                                                        G.node[doctor]
                                                        ["label"])

                    list_single_t_evolution.append(float(
                        len(list_I)))  #/(len(list_A)+len(list_F)))

                    t += 1

                ######## end t loop

                list_lists_t_evolutions.append(list_single_t_evolution)

                list_dist_fixed_parameters.append(
                    compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                        list_actual_evol_training, list_single_t_evolution))

                list_dist_abs_at_ending_point_fixed_parameters.append(
                    abs(list_single_t_evolution[-1] -
                        list_actual_evol_training[-1])
                )  # i save the distance at the ending point between the current simu and actual evol

                #  print "actual:",len(list_actual_evol_training),"  simu:",len(list_single_t_evolution)   # 125, 125

                list_final_num_infected.append(list_single_t_evolution[-1])

                list_dist_at_ending_point_fixed_parameters.append(
                    list_single_t_evolution[-1] - list_actual_evol_training[-1]
                )  # i save the distance at the ending point between the current simu and actual evol

            ######## end loop Niter for the training fase

            list_pair_dist_std_delta_end = []

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_fixed_parameters)
            )  # average dist between the curves over Niter
            list_pair_dist_std_delta_end.append(
                numpy.std(list_dist_fixed_parameters))

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

            file3 = open(output_file3, 'at')  # i print out the landscape
            print >> file3, prob_infection, prob_Immune, numpy.mean(
                list_dist_abs_at_ending_point_fixed_parameters
            ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                list_final_num_infected
            ), numpy.std(list_final_num_infected), numpy.std(
                list_final_num_infected) / numpy.mean(list_final_num_infected)
            file3.close()

            histogram_filename = "../Results/weight_shifts/histogr_raw_distances_ending_test_train_infection_p" + str(
                prob_infection) + "_Immune" + str(prob_Immune) + "_" + str(
                    Niter_training) + "iter_day" + str(cutting_day) + ".dat"
            histograma_gral_negv_posit.histograma(
                list_dist_at_ending_point_fixed_parameters, histogram_filename)

            histogram_filename2 = "../Results/weight_shifts/histogr_sum_dist_traject_infection_training_p" + str(
                prob_infection
            ) + "_" + "Immune" + str(prob_Immune) + "_" + str(
                Niter_training) + "iter_day" + str(cutting_day) + ".dat"

            histograma_bines_gral.histograma_bins(list_dist_fixed_parameters,
                                                  Nbins, histogram_filename2)

            print "written histogram file: ", histogram_filename
            print "written histogram file: ", histogram_filename2

            value = numpy.mean(list_dist_fixed_parameters) * numpy.mean(
                list_dist_abs_at_ending_point_fixed_parameters
            )  # if SD=0, it is a problem, because then that is the minimun value, but not the optimum i am looking for!!

            dict_filenames_prod_distances[output_file2] = value

            if (
                    numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)
            ) <= delta_end:  # i only consider situations close enough at the ending point

                dict_filenames_tot_distance[
                    output_file2] = list_pair_dist_std_delta_end

                print numpy.mean(list_dist_abs_at_ending_point_fixed_parameters
                                 ), "added scenario:", output_file2

        # file2 = open(output_file2,'at')
        #for s in range(len(list_single_t_evolution)):
        #   list_fixed_t=[]
        #  for iter in range (Niter_training):
        #     list_fixed_t.append(list_lists_t_evolutions[iter][s])
        #print >> file2, s,numpy.mean(list_fixed_t)
        #file2.close()

            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

    list_order_dict = compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
        dict_filenames_tot_distance, "Infection_training_weight", all_team,
        Niter_training, cutting_day)

    # it returns a list of tuples like this :  ('../Results/network_final_schedule_withTeam3_local/infection/Average_time_evolution_Infection_training_p0.7_Immune0.0_2iter_2012.dat', [2540.0, 208.0, 1.0])  the best set of parameters  being the fist one of the elements in the list.

    string_name = "infection_training_" + fixed_param + str(
        Niter_training) + "iter_day" + str(
            cutting_day
        ) + ".dat"  # for the "Results" file with the sorted list of files

    list_order_dict2 = compare_real_evol_vs_simus_to_be_called.pick_minimum_prod_distances(
        dict_filenames_prod_distances, string_name, all_team, Niter_training,
        cutting_day)

    optimum_filename = list_order_dict[0][0]
    prob_infection = float(list_order_dict[0][0].split("_p")[1].split("_")[0])
    prob_Immune = float(
        list_order_dict[0][0].split("_Immune")[1].split("_")[0])

    print "Optimum parameters (old method) at day", cutting_day, " are: p=", prob_infection, " and Pimmune=", prob_Immune

    #  i already know the optimum, now i run the dynamics with those values, starting from the average state on the cutting point, and test:

    optimum_filename = list_order_dict2[0][0]
    prob_infection = float(list_order_dict2[0][0].split("_p")[1].split("_")[0])
    prob_Immune = float(
        list_order_dict2[0][0].split("_Immune")[1].split("_")[0])

    print "Optimum parameters (product of distances along_traject and at the end) at day", cutting_day, " are: p=", prob_infection, " and Pimmune=", prob_Immune

    print "Run that simulation with the optimum parameter set:", optimum_filename

    print "printed out landscape file:", output_file3

    output_file10 = "../Results/weight_shifts/Summary_results_training_segment_infection_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_training) + "iter_avg_ic_day" + str(cutting_day) + ".dat"
    file10 = open(output_file10, 'wt')

    print >> file10, "Summary results from train-testing persuasion with", Niter_training, "iter , using all the individual cutting points as IC, and with values for the parameters:  prob_inf ", prob_infection, " prob immune: ", prob_Immune, "\n"

    print >> file10, "Look for the file (or run that simulation) with the optimum parameter set:", optimum_filename
    file10.close()
def main(graph_name):
 

   G = nx.read_gml(graph_name)
 
   list_id_weekends_T3=look_for_T3_weekends(G)  # T3 doesnt share fellows in the weekend  (but they are the exception)



   cutting_day=175  # to separate   training-testing

   Niter_training=1000
  

   delta_end=3  # >= than + or -  dr difference at the end of the evolution

   dir_real_data='../Results/'
   dir="../Results/weight_shifts/persuasion/"  


   all_team="NO"   # as adopters or not
   Nbins=20   # for the histogram of sum of distances


   fixed_param="FIXED_mutual0.5_damping.5_"    # or ""  # for the Results file that contains the sorted list of best parameters




  # fixed_parameters="mutual_encoug0.5_threshold0.5"   # for the Landscape text file CHANGE PARAMETERS ACCORDINGLY!!!

#output_file3="../Results/weight_shifts/Landscape_parameters_persuasion_train_test_"+str(fixed_parameters)+"_"+str(Niter_training)+"iter.dat"
   output_file3="../Results/weight_shifts/Landscape_parameters_persuasion_train_FIXED_damping0.1_threshold0.7_"+str(Niter_training)+"iter_alphaA_eq_alphaF.dat"  
   file3 = open(output_file3,'wt')        
   file3.close()

 


######################################################################################
#  I read the file of the actual evolution of the idea spreading in the hospital:   ##
######################################################################################



   if all_team=="YES":    
      print "remember that now i use the file of adopters without fellows\n../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
      exit()

   else:
      filename_actual_evol="../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
  


   file1=open(filename_actual_evol,'r')         ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
   list_lines_file=file1.readlines()
            

   list_actual_evol=[]  
   for line in list_lines_file:      # [1:]:   # i exclude the first row   
     
      num_adopters= float(line.split(" ")[1])          
      list_actual_evol.append(num_adopters)

   list_actual_evol_training=list_actual_evol[:cutting_day]

##################################################################


#../Results/network_final_schedule_withTeam3/Time_evolutions_Persuasion_alpha0.2_damping0.0_mutual_encourg0.7_threshold0.4_unif_distr_50iter_2012_seed31Oct_finalnetwork.dat

 
   alpha_F_min=0.10   #   # alpha=0: nobody changes their mind
   alpha_F_max=0.9    
   delta_alpha_F=0.10    #AVOID 1.0 OR THE DYNAMICS GETS TOTALLY STUCK AND IT IS NOT ABLE TO PREDICT SHIT!
   

   min_damping=0.500   #0.0     #its harder to go back from YES to NO again. =1 means no effect, =0.5 half the movement from Y->N than the other way around, =0 never go back from Y to N
   max_damping=0.501    #0.451
   delta_damping=0.10  
   
   


   min_mutual_encouragement=0.50   #  # when two Adopters meet, they convince each other even more
   max_mutual_encouragement=0.501   
   delta_mutual_encouragement=0.10
   
   
   threshold_min=0.10   #  # larger than, to be an Adopter
   threshold_max=0.901 
   delta_threshold=0.10   # AVOID 1.0 OR THE DYNAMICS GETS TOTALLY STUCK AND IT IS NOT ABLE TO PREDICT SHIT
 


   
   
   print "\n\nPersuasion process on network, with Niter:",Niter_training
   
   
   dict_filenames_tot_distance={}   # i will save the filename as key and the tot distance from that curve to the original one
   dict_filenames_prod_distances={}   


  

   threshold=threshold_min
   while   threshold<= threshold_max:
      print   "thershold:",threshold

      alpha_F=alpha_F_min
      while alpha_F<= alpha_F_max:            # i explore all the parameter space, and create a file per each set of values
        alpha_A=1.0*alpha_F
        print "  alpha_F:",alpha_F

        mutual_encouragement=min_mutual_encouragement  
        while  mutual_encouragement <= max_mutual_encouragement:
          print "    mutual_encouragement:",mutual_encouragement

          damping=min_damping
          while   damping <= max_damping:
            print "      damping:",damping


         
#            dir="../Results/weight_shifts/persuasion/alpha%.2f_damping%.2f/"  % (alpha_F, damping )
           
            output_file=dir+"Time_evolutions_Persuasion_training_alpha"+str(alpha_F)+"_damping"+str(damping)+"_mutual_encourg"+str(mutual_encouragement)+"_threshold"+str(threshold)+"_unif_distr_"+str(Niter_training)+"iter_alphaA_eq_alphaF"+"_"+str(cutting_day)+".dat"         


           # file = open(output_file,'wt')     # i am not saving the train file, because i will just want to know 
            #file.close()          # the optimum parameter set and go look for the whole-250-day file
            


            time_evol_number_adopters_ITER=[]  # list of complete single realizations of the dynamics
            list_dist_fixed_parameters=[]
            list_dist_at_ending_point_fixed_parameters=[]
            list_dist_abs_at_ending_point_fixed_parameters=[]

           
            list_networks_at_cutting_day=[]

            list_final_num_adopt=[]


            for iter in range(Niter_training):

               # print "         ",iter
                list_t=[]
           
                time_evol_number_adopters=[]   # for a single realization of the dynamics

               


                num_adopters , seed_shift ,max_shift= set_ic(G,threshold)   # i establish who is Adopter and NonAdopter initially, and count how many shifts i have total

                time_evol_number_adopters.append(float(num_adopters))               
                list_t.append(0)



                
               ########### the dynamics starts:                 
                t=int(seed_shift)+1   # the first time step is just IC.???


                while t< cutting_day:  # loop over shifts, in chronological order  (the order is the day index since seeding_day) 
                         
                    list_t.append(t)
                    for n in G.nodes():
                        if G.node[n]['type']=="shift" and G.node[n]['order']==t:  # i look for the shift corresponding to that time step                    

                            shift_lenght=int(G.node[n]['shift_lenght'])
                           
                            if shift_lenght==2 and n not in list_id_weekends_T3:
                               shift_lenght=1   # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)



                            flag_possible_persuasion=0
                            for doctor in G.neighbors(n):                               
                                if G.node[doctor]["status"]=="Adopter":   #first i check if any doctor is an adopter in this shift         
                                    flag_possible_persuasion=1                               
                                    break

                            if flag_possible_persuasion==1:
                                list_doctors=[]
                                for doctor in G.neighbors(n):   # for all drs in that shift
                                    list_doctors.append(doctor)
                                
                                
                                pairs=itertools.combinations(list_doctors,2)    # cos the shift can be 2 but also 3 doctors 
                                for pair in pairs:
                                    doctor1=pair[0]
                                    doctor2=pair[1]
                                                                                        
                                    if G.node[doctor1]['status'] != G.node[doctor2]['status']:  # if they think differently, 
                                                                                              # there will be persuasion
                                        persuasion(G,damping,doctor1,doctor2,alpha_A,alpha_F,threshold,shift_lenght)   # i move their values of opinion                  
                                        update_opinions(G,threshold,doctor1,doctor2) #  i update status and make sure the values of the vectors stay between [0,1] 
                                  
                                    else:  # if two Adopters meet, they encourage each other (if two NonAdopters, nothing happens)
                                   
                                       mutual_reinforcement(G,mutual_encouragement,doctor1,doctor2,shift_lenght)
                                  
                               
                    list_all_Adopters=[]  #including fellows        
                    list_Adopters=[]        #NOT including fellows 
                    for n in G.nodes():              
                        try:
                            if  G.node[n]["status"]=="Adopter":                                                    
                                if G.node[n]["label"] not in list_Adopters and G.node[n]["type"]=="A":
                                    list_Adopters.append(G.node[n]["label"])
                        except: pass  # if the node is a shift, it doesnt have a 'status' attribute


        
                   


                    time_evol_number_adopters.append(float(len(list_Adopters)))

                    t+=1
   

                ############## end while loop over t
               


               
                time_evol_number_adopters_ITER.append(time_evol_number_adopters)


                list_final_num_adopt.append(time_evol_number_adopters[-1])

               
                list_dist_fixed_parameters.append(compare_real_evol_vs_simus_to_be_called.compare_two_curves( list_actual_evol_training,time_evol_number_adopters))
               
                list_dist_abs_at_ending_point_fixed_parameters.append( abs(time_evol_number_adopters[-1]-list_actual_evol_training[-1]) )

                list_dist_at_ending_point_fixed_parameters.append( time_evol_number_adopters[-1]-list_actual_evol_training[-1]) 



               
              
             

            #######################   end loop Niter for the training fase


            list_pair_dist_std_delta_end=[]
        
            list_pair_dist_std_delta_end.append(numpy.mean(list_dist_fixed_parameters) )   # average dist between the curves over Niter
            list_pair_dist_std_delta_end.append(numpy.std(list_dist_fixed_parameters) )

            list_pair_dist_std_delta_end.append(numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

         

                     
            value=numpy.mean(list_dist_fixed_parameters) *numpy.mean(list_dist_abs_at_ending_point_fixed_parameters) # if SD=0, it is a problem, because then that is the minimun value, but not the optimum i am looking for!!
        
            dict_filenames_prod_distances[output_file]=  value                  



            file3 = open(output_file3,'at')          # i print out the landscape           
            print >> file3, alpha_F, damping, mutual_encouragement, threshold,numpy.mean(list_dist_abs_at_ending_point_fixed_parameters), numpy.mean(list_dist_fixed_parameters),  numpy.mean(list_final_num_adopt),numpy.std(list_final_num_adopt),  numpy.std(list_final_num_adopt)/numpy.mean(list_final_num_adopt)
            file3.close()




            histogram_filename="../Results/weight_shifts/histogr_raw_distances_ending_test_train_alpha"+str(alpha_F)+"_damping"+str(damping)+"_mutual_encourg"+str(mutual_encouragement)+"_threshold"+str(threshold)+"_unif_distr_"+str(Niter_training)+"iter_alphaA_eq_alphaF"+"_"+str(cutting_day)+".dat"     
            histograma_gral_negv_posit.histograma(list_dist_at_ending_point_fixed_parameters,histogram_filename)
            
            histogram_filename2="../Results/weight_shifts/histogr_sum_dist_traject_infection_training_alpha"+str(alpha_F)+"_damping"+str(damping)+"_mutual_encourg"+str(mutual_encouragement)+"_threshold"+str(threshold)+"_unif_distr_"+str(Niter_training)+"iter_alphaA_eq_alphaF"+"_"+str(cutting_day)+".dat"     
            
            histograma_bines_gral.histograma_bins(list_dist_fixed_parameters,Nbins,histogram_filename2)


            print  "written histogram file: ",histogram_filename
            print  "written histogram file: ",histogram_filename2


            if (numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)) <= delta_end:  # i only consider situations close enough at the ending point   

               dict_filenames_tot_distance[output_file]=list_pair_dist_std_delta_end 


             



   
          #  file = open(output_file,'wt')        
           # for i in range(len(time_evol_number_adopters)):  #time step by time step
            #    list_fixed_t=[]
             #   for iteracion in range (Niter_training): #loop over all independent iter of the process
              #      list_fixed_t.append(time_evol_number_adopters_ITER[iteracion][i])  # i collect all values for the same t, different iter  

               # print >> file, list_t[i],numpy.mean(list_fixed_t),numpy.std(list_fixed_t), alpha_F,damping,mutual_encouragement       
            #file.close()

           

          
            damping += delta_damping
          mutual_encouragement += delta_mutual_encouragement
        alpha_F += delta_alpha_F
      threshold  += delta_threshold
    



   list_order_dict=  compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(dict_filenames_tot_distance,"Persuasion_training_land_weight",all_team,Niter_training,cutting_day)


  
   string_name="_persuasion_training_"+fixed_param+str(Niter_training)+"iter_"+str(cutting_day)+".dat"            # for the "Results" file with the sorted list of files
   
   list_order_dict2= compare_real_evol_vs_simus_to_be_called.pick_minimum_prod_distances(dict_filenames_prod_distances,string_name,all_team,Niter_training,cutting_day)

  


#./Results/network_final_schedule_withTeam3_local/Time_evolutions_Persuasion_alpha0.4_damping0.4_mutual_encourg0.6_threshold0.5_unif_distr_2iter_2012_seed31Oct_finalnetwork.dat


   optimum_filename=list_order_dict[0][0]


   print optimum_filename   
   alpha_F=float(list_order_dict[0][0].split("_alpha")[1].split("_")[0])
   alpha_A=0.5*alpha_F
   damping=float(list_order_dict[0][0].split("_damping")[1].split("_")[0])
   mutual_encouragement=float(list_order_dict[0][0].split("_mutual_encourg")[1].split("_")[0])
   threshold=float(list_order_dict[0][0].split("_threshold")[1].split("_")[0])
  
  
            
                

  
   print "Optimum (old method) alpha=", alpha_F, " damping=",damping," mutual encourag=",mutual_encouragement," threshold",threshold
   
  
  
   optimum_filename=list_order_dict2[0][0]

   print optimum_filename   
   alpha_F=float(list_order_dict2[0][0].split("_alpha")[1].split("_")[0])
   alpha_A=0.5*alpha_F
   damping=float(list_order_dict2[0][0].split("_damping")[1].split("_")[0])
   mutual_encouragement=float(list_order_dict2[0][0].split("_mutual_encourg")[1].split("_")[0])
   threshold=float(list_order_dict2[0][0].split("_threshold")[1].split("_")[0])
  
  
            
                

  
   print "Optimum (product distances and SDs) alpha=", alpha_F, " damping=",damping," mutual encourag=",mutual_encouragement," threshold",threshold
   
  
  





   output_file10="../Results/weight_shifts/Summary_results_train_test_persuasion_alpha"+str(alpha_F)+"_FIXED_damping"+str(damping)+"_mutual_encourg"+str(mutual_encouragement)+"_FIXED_threshold"+str(threshold)+"_"+str(Niter_training)+"iter_alphaA_eq_alphaF_day"+str(cutting_day)+".dat"         
   file10 = open(output_file10,'wt')    

   print >> file10, "Summary results from train-testing persuasion with",Niter_training, "iter, using the avg of the cutting points as IC, and with values for the parameters:  alpha ",alpha_F," damping: ",damping," mutual_encourg: ",mutual_encouragement," threshold:",threshold


   print >> file10,  "Look for optimum the file set of parameters (or run those simulations):",optimum_filename
  

   file10.close()




   print "Look for optimum the file set of parameters (or run those simulations):",optimum_filename
  

   print "printed out landscape file:",output_file3
def main(graph_name):

    G = nx.read_gml(graph_name)

    Niter = 1000
    delta_end = 3  # >= than + or -  dr difference at the end of the evolution

    dir_real_data = '../Results/'

    all_team = "NO"  # as adopters or not

    # output_file3=dir_real_data+"Landscape_parameters_persuasion_"+str(Niter)+"iter.dat
    #file3 = open(output_file3,'wt')

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    if all_team == "YES":
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_all_team_as_adopters_SIMPLER.csv"

    else:
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_SIMPLER.csv"
    #ya no necesito CAMBIAR TB EL NOMBRE DEL ARCHIVO EN EL CODIGO PARA COMPARAR CURVAs

    list_actual_evol = []
    result_actual_file = csv.reader(open(filename_actual_evol, 'rb'),
                                    delimiter=',')
    cont = 0
    for row in result_actual_file:
        if cont > 0:  # i ignore the first line with the headers

            num_adopters = row[3]

            list_actual_evol.append(float(num_adopters))

        cont += 1

##################################################################

#../Results/network_final_schedule_withTeam3/Time_evolutions_Persuasion_alpha0.2_damping0.0_mutual_encourg0.7_threshold0.4_unif_distr_50iter_2012_seed31Oct_finalnetwork.dat

    alpha_F_min = 0.0  # alpha=0: nobody changes their mind
    alpha_F_max = 1.001
    delta_alpha_F = 0.1

    min_damping = 0.0  #its harder to go back from YES to NO again. =1 means no effect, =0.5 half the movement from Y->N than the other way around, =0 never go back from Y to N
    max_damping = 1.01
    delta_damping = 0.1

    min_mutual_encouragement = 0.0  # when two Adopters meet, they convince each other even more
    max_mutual_encouragement = 1.01
    delta_mutual_encouragement = 0.1

    print "\n\nPersuasion process on network, with Niter:", Niter

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    alpha_F = alpha_F_min
    while alpha_F <= alpha_F_max:  # i explore all the parameter space, and create a file per each set of values
        alpha_A = 0.5 * alpha_F
        print "  alpha_F:", alpha_F

        mutual_encouragement = min_mutual_encouragement
        while mutual_encouragement <= max_mutual_encouragement:
            print "    mutual_encouragement:", mutual_encouragement

            damping = min_damping
            while damping <= max_damping:
                print "      damping:", damping

                dir = "../Results/network_final_schedule_withTeam3_local/"
                output_file = dir + "Time_evolutions_Persuasion_alpha" + str(
                    alpha_F) + "_damping" + str(
                        damping) + "_mutual_encourg" + str(
                            mutual_encouragement) + "_" + str(
                                Niter) + "iter_distributed_thresholds.dat"
                file = open(output_file, 'wt')
                file.close()

                time_evol_number_adopters_ITER = [
                ]  # list of complete single realizations of the dynamics
                list_dist_fixed_parameters = []
                list_dist_at_ending_point_fixed_parameters = []

                for iter in range(Niter):

                    print "         ", iter
                    list_t = []

                    time_evol_number_adopters = [
                    ]  # for a single realization of the dynamics

                    num_adopters, seed_shift, max_shift = set_ic(
                        G
                    )  # i establish who is Adopter and NonAdopter initially, and count how many shifts i have total

                    time_evol_number_adopters.append(float(num_adopters))
                    # print "initial number of adopters:", num_adopters
                    list_t.append(0)

                    # the dynamics starts:
                    t = int(
                        seed_shift) + 1  # the first time step is just IC.???

                    while t <= max_shift:  # loop over shifts, in chronological order  (the order is the day index since seeding_day)

                        list_t.append(t)
                        for n in G.nodes():
                            if G.node[n]['type'] == "shift" and G.node[n][
                                    'order'] == t:  # i look for the shift corresponding to that time step
                                flag_possible_persuasion = 0
                                for doctor in G.neighbors(n):
                                    if G.node[doctor][
                                            "status"] == "Adopter":  #first i check if any doctor is an adopter in this shift
                                        flag_possible_persuasion = 1
                                        break

                                if flag_possible_persuasion == 1:
                                    list_doctors = []
                                    for doctor in G.neighbors(
                                            n):  # for all drs in that shift
                                        list_doctors.append(doctor)

                                    pairs = itertools.combinations(
                                        list_doctors, 2
                                    )  # cos the shift can be 2 but also 3 doctors
                                    for pair in pairs:
                                        doctor1 = pair[0]
                                        doctor2 = pair[1]

                                        if G.node[doctor1]['status'] != G.node[
                                                doctor2][
                                                    'status']:  # if they think differently,
                                            # there will be persuasion
                                            persuasion(
                                                G, damping, doctor1, doctor2,
                                                alpha_A, alpha_F
                                            )  # i move their values of opinion
                                            update_opinions(
                                                G, doctor1, doctor2
                                            )  #  i update status and make sure the values of the vectors stay between [0,1]

                                        else:  # if two Adopters meet, they encourage each other (if two NonAdopters, nothing happens)

                                            mutual_reinforcement(
                                                G, mutual_encouragement,
                                                doctor1, doctor2)

                        list_Adopters = []  #count how many i have at this time
                        for n in G.nodes():
                            try:
                                if G.node[n]["status"] == "Adopter":
                                    if G.node[n]["label"] not in list_Adopters:
                                        list_Adopters.append(
                                            G.node[n]["label"])
                            except:
                                pass  # if the node is a shift, it doesnt have a 'status' attribute

                        time_evol_number_adopters.append(
                            float(len(list_Adopters)))

                        t += 1

                    ############## end while loop over t

                    time_evol_number_adopters_ITER.append(
                        time_evol_number_adopters)

                    list_dist_fixed_parameters.append(
                        compare_real_evol_vs_simus_to_be_called.
                        compare_two_curves(list_actual_evol,
                                           time_evol_number_adopters))

                    list_dist_at_ending_point_fixed_parameters.append(
                        abs(time_evol_number_adopters[-1] -
                            list_actual_evol[-1]))

                #######################end loop over Niter

                list_pair_dist_std_delta_end = []

                list_pair_dist_std_delta_end.append(
                    numpy.mean(list_dist_fixed_parameters)
                )  # average dist between the curves over Niter
                list_pair_dist_std_delta_end.append(
                    numpy.std(list_dist_fixed_parameters))

                list_pair_dist_std_delta_end.append(
                    numpy.mean(list_dist_at_ending_point_fixed_parameters))

                if (
                        numpy.mean(list_dist_at_ending_point_fixed_parameters)
                ) <= delta_end:  # i only consider situations close enough at the ending point

                    dict_filenames_tot_distance[
                        output_file] = list_pair_dist_std_delta_end

                file = open(output_file, 'wt')
                for i in range(len(
                        time_evol_number_adopters)):  #time step by time step
                    list_fixed_t = []
                    for iteracion in range(
                            Niter
                    ):  #loop over all independent iter of the process
                        list_fixed_t.append(
                            time_evol_number_adopters_ITER[iteracion][i]
                        )  # i collect all values for the same t, different iter

                    print >> file, list_t[i], numpy.mean(
                        list_fixed_t), numpy.std(
                            list_fixed_t
                        ), alpha_F, damping, mutual_encouragement
                file.close()

                #    print len(list_t), len(time_evol_number_adopters)

                #  histograma_bines_gral.histograma_bins(list_dist_fixed_parameters,50, "../Results/histogr_distances_indiv_pers_simus_to_the_average_curve_alpha"+str(alpha_F)+"_damping"+str(damping)+"_mutual_encourg"+str(mutual_encouragement)+"_threshold"+str(threshold)+"_unif_distr_"+str(Niter)+"iter.dat")  # Nbins=100

                damping += delta_damping
            mutual_encouragement += delta_mutual_encouragement
        alpha_F += delta_alpha_F

    compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
        dict_filenames_tot_distance, "Persuasion_distributed_thresholds",
        all_team, Niter)
def main(graph_name):

    G = nx.read_gml(graph_name)

    all_team = "NO"  # as adopters or not

    dir_real_data = '../Results/'

    delta_end = 3  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

    Niter = 100

    list_id_weekends_T3 = look_for_T3_weekends(
        G
    )  # T3 doesnt share fellows in the weekend  (but they are the exception)

    output_file3 = "../Results/weight_shifts/Landscape_parameters_infection_memory_fixed_dose_thr_" + str(
        Niter) + "iter.dat"
    file3 = open(output_file3, 'wt')
    file3.close()

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    if all_team == "YES":
        print "remember that now i use the file of adopters without fellows\n../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
        exit()

    else:
        filename_actual_evol = "../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"

    file1 = open(
        filename_actual_evol, 'r'
    )  ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
    list_lines_file = file1.readlines()

    list_actual_evol = []
    for line in list_lines_file:  # [1:]:   # i exclude the first row

        num_adopters = float(line.split(" ")[1])
        list_actual_evol.append(num_adopters)

################################################################################

    prob_min = 0.00
    prob_max = 1.01
    delta_prob = 0.1

    prob_Immune_min = 0.0
    prob_Immune_max = 1.0
    delta_prob_Immune = 0.1

    infect_threshold_min = 0.0  # for someone to become infected
    infect_threshold_max = 1.01
    delta_infect_threshold = 0.1

    dose_min = 0.1  # of a single encounter with an infected  (starting from zero doesnt make sense)
    dose_max = 1.01
    delta_dose = 0.1

    dir = "../Results/weight_shifts/infection/"

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            infect_threshold = infect_threshold_min
            while infect_threshold <= infect_threshold_max:

                print "  threshold:", infect_threshold

                dose = dose_min
                while dose <= dose_max:

                    print "  dose:", dose

                    output_file2 = dir + "Average_time_evolution_Infection_memory_p" + str(
                        prob_infection) + "_" + "Immune" + str(
                            prob_Immune) + "_threshold" + str(
                                infect_threshold) + "_dose" + str(
                                    dose) + "_" + str(Niter) + "iter.dat"
                    file2 = open(output_file2, 'wt')
                    file2.close()

                    num_shifts = 0
                    for n in G.nodes():
                        G.node[n]["status"] = "S"
                        G.node[n][
                            "infec_value"] = 0.  # when this value goes over the infect_threshold, the dr is infected
                        if G.node[n]['type'] == "shift":
                            num_shifts += 1

                    list_lists_t_evolutions = [
                    ]  # i create the empty list of list for the Niter temporal evolutions

                    list_dist_fixed_parameters = []
                    list_abs_dist_at_ending_point_fixed_parameters = []
                    list_final_num_infected = []

                    for iter in range(Niter):

                        print "     iter:", iter

                        list_I = []  #list infected doctors
                        list_ordering = []
                        list_s = []

                        ########### set I.C.

                        max_order = 0
                        for n in G.nodes():
                            G.node[n][
                                "status"] = "S"  # all nodes are Susceptible
                            if G.node[n]['type'] == "shift":
                                list_s.append(n)
                                if G.node[n]['order'] > max_order:
                                    max_order = G.node[n]['order']
                            else:
                                if G.node[n]['label'] == "Wunderink" or G.node[
                                        n]["label"] == "Weiss":
                                    G.node[n]["status"] = "I"
                                    list_I.append(G.node[n]['label'])

                        list_single_t_evolution = []
                        list_single_t_evolution.append(
                            2.0)  # I always start with TWO infected doctors!!

                        for n in G.nodes(
                        ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                            if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                              == "F"):
                                if G.node[n]['label'] != "Wunderink" and G.node[
                                        n]["label"] != "Weiss":
                                    rand = random.random()
                                    if rand < prob_Immune:
                                        G.node[n]["status"] = "Immune"

                        ################# the dynamics starts:

                        t = 1
                        while t <= max_order:  # loop over shifts, in order
                            for n in G.nodes():
                                if G.node[n]['type'] == "shift" and G.node[n][
                                        'order'] == t:
                                    shift_lenght = int(
                                        G.node[n]['shift_lenght'])

                                    if shift_lenght == 2 and n not in list_id_weekends_T3:
                                        shift_lenght = 1  # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)

                                    flag_possible_infection = 0
                                    for doctor in G.neighbors(
                                            n
                                    ):  #first i check if any doctor is infected in this shift
                                        if G.node[doctor]["status"] == "I":
                                            flag_possible_infection = 1

                                    if flag_possible_infection:
                                        for doctor in G.neighbors(
                                                n
                                        ):  # then the doctors in that shift, gets infected with prob_infection

                                            for i in range(shift_lenght):
                                                if G.node[doctor][
                                                        "status"] == "S":
                                                    rand = random.random()
                                                    if rand < prob_infection:  # with prob p the infection occurres

                                                        G.node[doctor][
                                                            "infec_value"] += dose  # and bumps the infection_value of that susceptible dr

                                                        if G.node[doctor][
                                                                "infec_value"] >= infect_threshold:  # becomes  infected

                                                            G.node[doctor][
                                                                "status"] = "I"
                                                            if G.node[doctor][
                                                                    "type"] == "A":  # fellows participate in the dynamics, but i only consider the attendings as real adopters
                                                                list_I.append(
                                                                    G.node[
                                                                        doctor]
                                                                    ["label"])

                            list_single_t_evolution.append(float(len(list_I)))

                            t += 1
                            ######## end t loop

                        list_lists_t_evolutions.append(list_single_t_evolution)

                        list_dist_fixed_parameters.append(
                            compare_real_evol_vs_simus_to_be_called.
                            compare_two_curves(list_actual_evol,
                                               list_single_t_evolution))

                        list_abs_dist_at_ending_point_fixed_parameters.append(
                            abs(list_single_t_evolution[-1] -
                                list_actual_evol[-1])
                        )  # i save the distance at the ending point between the current simu and actual evol

                        list_final_num_infected.append(
                            list_single_t_evolution[-1])

                        ######## end loop Niter

                    list_pair_dist_std_delta_end = []

                    list_pair_dist_std_delta_end.append(
                        numpy.mean(list_dist_fixed_parameters)
                    )  # average dist between the curves over Niter
                    list_pair_dist_std_delta_end.append(
                        numpy.std(list_dist_fixed_parameters))

                    list_pair_dist_std_delta_end.append(
                        numpy.mean(
                            list_abs_dist_at_ending_point_fixed_parameters))

                    file3 = open(output_file3,
                                 'at')  # i print out the landscape
                    print >> file3, prob_infection, prob_Immune, numpy.mean(
                        list_abs_dist_at_ending_point_fixed_parameters
                    ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                        list_final_num_infected), numpy.std(
                            list_final_num_infected
                        ), numpy.std(list_final_num_infected) / numpy.mean(
                            list_final_num_infected)
                    file3.close()

                    if (
                            numpy.mean(
                                list_abs_dist_at_ending_point_fixed_parameters)
                    ) <= delta_end:  # i only consider situations close enough at the ending point

                        dict_filenames_tot_distance[
                            output_file2] = list_pair_dist_std_delta_end

            #  print >> file3, prob_infection,prob_Immune,dict_filenames_tot_distance[output_file2][0],dict_filenames_tot_distance[output_file2][1]

                    file2 = open(output_file2, 'at')
                    for s in range(len(list_single_t_evolution)):
                        list_fixed_t = []
                        for iter in range(Niter):
                            list_fixed_t.append(
                                list_lists_t_evolutions[iter][s])
                        print >> file2, s, numpy.mean(list_fixed_t)
                    file2.close()

                    print list_dist_fixed_parameters

                    # histograma_bines_gral.histograma_bins(list_dist_fixed_parameters,50, "../Results/histogr_distances_indiv_infect_memory_simus_to_the_average_curve_p"+str(prob_infection)+"_"+"Immune"+str(prob_Immune)+"_threshold"+str(infect_threshold)+"_dose"+str(dose)+"_"+str(Niter)+"iter.dat" )  # Nbins=100

                    dose += delta_dose
                infect_threshold += delta_infect_threshold
            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

    compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
        dict_filenames_tot_distance, "Infection_memory", all_team, Niter, None)
    print "written landscape file:", output_file3
예제 #13
0
            print >> file2, s,numpy.mean(list_fixed_t)                    
        file2.close()




      #  print list_dist_fixed_parameters

       # histograma_bines_gral.histograma_bins(list_dist_fixed_parameters,50, "../Results/weight_shifts/histogr_distances_indiv_infect_simus_to_the_average_curve_p"+str(prob_infection)+"_"+"Immune"+str(prob_Immune)+"_"+str(Niter)+"iter.dat")  # Nbins=100



        prob_infection+= delta_prob
      prob_Immune+= delta_prob_Immune

   compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(dict_filenames_tot_distance,"Infection_weight",all_team,Niter,None)  # last argument doesnt apply (cutting day)

  
   print "written landscape file:",output_file3



######################################
######################################



def look_for_T3_weekends(G):

   list_ids_T3_weekends=[]
   for n in G.nodes():
def main(graph_name):
 


   cutting_day=125  # to separate   training-testing


   G = nx.read_gml(graph_name)


   all_team="NO"   # as adopters or not

   list_id_weekends_T3=look_for_T3_weekends(G)  # T3 doesnt share fellows in the weekend  (but they are the exception)


   dir_real_data='../Results/'


   delta_end=3  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

   Niter=1000
  
 

######################################################################################
#  I read the file of the actual evolution of the idea spreading in the hospital:   ##
######################################################################################



   if all_team=="YES":    
      print "remember that now i use the file of adopters without fellows\n../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
      exit()

   else:
      filename_actual_evol="../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
  


   file1=open(filename_actual_evol,'r')         ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
   list_lines_file=file1.readlines()
            

   list_actual_evol=[]  
   for line in list_lines_file:      # [1:]:   # i exclude the first row   
     
      num_adopters= float(line.split(" ")[1])          
      list_actual_evol.append(num_adopters)



   list_actual_evol_training=list_actual_evol[:cutting_day]
   list_actual_evol_testing=list_actual_evol[(cutting_day-1):]
   

##################################################################



#../Results/network_final_schedule_withTeam3/infection/Average_time_evolution_Infection_p0.9_Immune0.5_1000iter_2012.dat

   prob_min=0.00
   prob_max=1.01
   delta_prob=0.1
      

   prob_Immune_min=0.0  # no immune people
   prob_Immune_max=0.0
   delta_prob_Immune=0.1 


   range_distrib_threshold=0.2  # for the uniform distrib to go : 0 to ...
 
   range_distrib_dose=0.2  # for the uniform distrib to go : 0 to ...
   range_distrib_dose=0.2  # for the uniform distrib to go : 0 to ...
   range_distrib_dose=0.2  # for the uniform distrib to go : 0 to ...


   dir="../Results/weight_shifts/infection/"    

   dict_filenames_tot_distance={}   # i will save the filename as key and the tot distance from that curve to the original one

  

   prob_Immune=prob_Immune_min
   while prob_Immune<= prob_Immune_max:
        
      print "prom Immune:",prob_Immune        

      prob_infection=prob_min
      while prob_infection<= prob_max:
                 
               print "  p:",prob_infection       
         
         
        




               output_file2=dir+"Average_time_evolution_Infection_memory_dose_thr_from_distr_training_p"+str(prob_infection)+"_"+"FIXED_Immune"+str(prob_Immune)+"_"+str(Niter)+"iter_day"+str(cutting_day)+".dat"
            #   file2 = open(output_file2,'wt')                                     
             #  file2.close()
               




               num_Drs=0.
               num_shifts=0
               for n in G.nodes():
                  G.node[n]["status"]="S" 
                  G.node[n]["infec_value"]=0.   # when this value goes over the infect_threshold, the dr is infected
                  G.node[n]["personal_threshold"]=random.random()  # for a dr to become infected

                  if G.node[n]['type']=="shift":
                     num_shifts+=1
                  else:
                     num_Drs+=1.

      
               list_lists_t_evolutions=[]     # i create the empty list of list for the Niter temporal evolutions
               
               list_dist_fixed_parameters=[]
               list_dist_abs_at_ending_point_fixed_parameters=[]
               
               
               for iter in range(Niter):
            
                  print "     iter:",iter


                  list_I=[]  #list infected doctors
                  list_ordering=[]
                  list_s=[]
                  

            ########### set I.C.

                  max_order=0
                  for n in G.nodes():
                     G.node[n]["status"]="S"  # all nodes are Susceptible
                     if G.node[n]['type']=="shift":
                        list_s.append(n)        
                        if  G.node[n]['order']>max_order:
                           max_order=G.node[n]['order']
                     else:
                        if G.node[n]['label']=="Wunderink"  or G.node[n]["label"]=="Weiss":           
                           G.node[n]["status"]="I"                       
                           list_I.append(G.node[n]['label'])
          

            
           
                  list_single_t_evolution=[]
                  list_single_t_evolution.append(2.0)  # I always start with TWO infected doctors!!


                  for n in G.nodes():   # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                     if (G.node[n]['type']=="A") or ( G.node[n]['type']=="F"):
                        if G.node[n]['label']!="Wunderink"  and G.node[n]["label"]!="Weiss": 
                           rand=random.random()
                           if rand< prob_Immune:
                              G.node[n]["status"]="Immune"
                              


        
  
                  ################# the dynamics starts: 
            
                  t=1
                  while t< cutting_day:  # loop over shifts, in order           
                     for n in G.nodes():
                        if G.node[n]['type']=="shift" and G.node[n]['order']==t:
                           shift_lenght=int(G.node[n]['shift_lenght'])

                           if shift_lenght==2 and n not in list_id_weekends_T3:
                              shift_lenght=1   # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)
                         #  print "one-day weekend", G.node[n]['label'],G.node[n]['shift_lenght']

                           flag_possible_infection=0
                           for doctor in G.neighbors(n): #first i check if any doctor is infected in this shift
                              if G.node[doctor]["status"]=="I":
                                 flag_possible_infection=1
                                

                           if flag_possible_infection:
                              for doctor in G.neighbors(n): # then the doctors in that shift, gets infected with prob_infection
                                    for i in range(shift_lenght):   # i repeat the infection process several times, to acount for shift lenght
                                       if G.node[doctor]["status"]=="S":
                                          rand=random.random()
                                          if rand<prob_infection:  # with prob p the infection occurres
                                             
                                             G.node[doctor]["infec_value"]+=random.random()  # and bumps the infection_value of that susceptible dr (the dose is random, not fixed)
                                       
                                             if G.node[doctor]["infec_value"]>= G.node[doctor]["personal_threshold"]:  # the threshold for infection is personal
                                                
                                                G.node[doctor]["status"]="I"
                                                if G.node[doctor]["type"]=="A":   # fellows participate in the dynamics, but i only consider the attendings as real adopters
                                                   list_I.append(G.node[doctor]["label"])
                                          

                     list_single_t_evolution.append(float(len(list_I)))

                     t+=1   
                     ######## end t loop




              
                  list_lists_t_evolutions.append(list_single_t_evolution)
             
 
                  #print "actual:",len(list_actual_evol_training),"  simu:",len(list_single_t_evolution)
                  list_dist_fixed_parameters.append(compare_real_evol_vs_simus_to_be_called.compare_two_curves( list_actual_evol_training,list_single_t_evolution))
                  
                  list_dist_abs_at_ending_point_fixed_parameters.append( abs(list_single_t_evolution[-1]-list_actual_evol_training[-1]) )   # i save the distance at the ending point between the current simu and actual evol

          
           
                  ######## end loop Niter for the training fase
      

       


       
       
               list_pair_dist_std_delta_end=[]
               
               list_pair_dist_std_delta_end.append(numpy.mean(list_dist_fixed_parameters) )   # average dist between the curves over Niter
               list_pair_dist_std_delta_end.append(numpy.std(list_dist_fixed_parameters) )
               
               list_pair_dist_std_delta_end.append(numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))
               
               
    
               
               if (numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)) <= delta_end:  # i only consider situations close enough at the ending point   
          
                  dict_filenames_tot_distance[output_file2]=list_pair_dist_std_delta_end



            #  file2 = open(output_file2,'at')        
             #  for s in range(len(list_single_t_evolution)):           
              #   list_fixed_t=[]
               #   for iter in range (Niter):
                #     list_fixed_t.append(list_lists_t_evolutions[iter][s])        
                 # print >> file2, s,numpy.mean(list_fixed_t)                    
#               file2.close()


               print list_dist_fixed_parameters

             


              
               prob_infection+= delta_prob
      prob_Immune+= delta_prob_Immune




   list_order_dict= compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(dict_filenames_tot_distance,"Infection_memory_distrib_training",all_team,Niter,cutting_day)
# it returns a list of tuples like this :  ('../Results/network_final_schedule_withTeam3_local/infection/Average_time_evolution_Infection_training_p0.7_Immune0.0_2iter_2012.dat', [2540.0, 208.0, 1.0])  the best set of parameters  being the fist one of the elements in that list.





#Average_time_evolution_Infection_memory_train_test_p"+str(prob_infection)+"_"+"Immune"+str(prob_Immune)+"_threshold"+str(infect_threshold)+"_dose"+str(dose)+"_"+str(Niter)+"iter_avg_ic.dat

   optimum_filename=list_order_dict[0][0]
   
   prob_infection=float(list_order_dict[0][0].split("_p")[1].split("_")[0])
   prob_Immune=float(list_order_dict[0][0].split("_Immune")[1].split("_")[0])
  
  
   
   
   print "Optimum parameters at day",cutting_day," are: p=",prob_infection," Pimmune=",prob_Immune
예제 #15
0
def main(graph_name):

    cutting_day = 125  # to separate   training-testing

    G = nx.read_gml(graph_name)

    all_team = "NO"  # as adopters or not

    dir_real_data = '../Results/'

    delta_end = 3  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)

    Niter_training = 1000
    Niter_testing = 1000

    ######################################################################################
    #  I read the file of the actual evolution of the idea spreading in the hospital:   ##
    ######################################################################################

    if all_team == "YES":
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_all_team_as_adopters_SIMPLER.csv"

    else:
        filename_actual_evol = dir_real_data + "HospitalModel_august1_adoption_counts_SIMPLER.csv"
    #ya no necesito CAMBIAR TB EL NOMBRE DEL ARCHIVO EN EL CODIGO PARA COMPARAR CURVAs

    list_actual_evol = []
    result_actual_file = csv.reader(open(filename_actual_evol, 'rb'),
                                    delimiter=',')
    cont = 0
    for row in result_actual_file:
        if cont > 0:  # i ignore the first line with the headers

            num_adopters = row[3]

            list_actual_evol.append(float(num_adopters))

        cont += 1

    list_actual_evol_training = list_actual_evol[:cutting_day]
    list_actual_evol_testing = list_actual_evol[(cutting_day - 1):]

    ##################################################################

    #../Results/network_final_schedule_withTeam3/infection/Average_time_evolution_Infection_p0.9_Immune0.5_1000iter_2012.dat

    prob_min = 0.09
    prob_max = 1.01
    delta_prob = 0.1

    prob_Immune_min = 0.00
    prob_Immune_max = 1.01
    delta_prob_Immune = 0.1

    dir = "../Results/network_final_schedule_withTeam3_local/infection/"

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    dict_filenames_list_dict_network_states = {
    }  # i will save the filename as key and the list of networks at cutting day as value

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            output_file2 = dir + "Average_time_evolution_Infection_training_p" + str(
                prob_infection) + "_" + "Immune" + str(
                    prob_Immune) + "_" + str(Niter_training) + "iter_2012.dat"
            file2 = open(output_file2, 'wt')
            file2.close()

            # i create the empty list of list for the Niter temporal evolutions
            num_shifts = 0
            for n in G.nodes():
                G.node[n]["status"] = "S"
                if G.node[n]['type'] == "shift":
                    num_shifts += 1

        #  list_final_I_values_fixed_p=[]  # i dont care about the final values right now, but about the whole time evol
            list_lists_t_evolutions = []

            list_dist_fixed_parameters = []
            list_dist_abs_at_ending_point_fixed_parameters = []

            list_dict_network_states = []

            for iter in range(Niter_training):

                print "     iter:", iter

                dict_network_states = {}

                #######OJO~!!!!!!!!!! COMENTAR ESTO CUANDO ESTOY BARRIENDO TOOOOOOOOOODO EL ESPACIO DE PARAMETROS
                #   file_name_indiv_evol=output_file2.strip("Average_").split('.dat')[0]+"_indiv_iter"+str(iter)+".dat"

                #  file4 = open(file_name_indiv_evol,'wt')
                # file4.close()
                ##########################################

                list_I = []  #list infected doctors
                list_ordering = []
                list_s = []
                list_A = []
                list_F = []

                ########### set I.C.

                max_order = 0
                for n in G.nodes():
                    G.node[n]["status"] = "S"  # all nodes are Susceptible
                    if G.node[n]['type'] == "shift":
                        list_s.append(n)
                        if G.node[n]['order'] > max_order:
                            max_order = G.node[n]['order']
                    else:
                        if G.node[n]['label'] == "Wunderink" or G.node[n][
                                "label"] == "Weiss":
                            G.node[n]["status"] = "I"
                            list_I.append(G.node[n]['label'])

                            ######################## WHAT ABOUT SMITH AND SPORN???

                        if G.node[n]['type'] == "A":
                            list_A.append(n)

                        if G.node[n]['type'] == "F":
                            list_F.append(n)

                list_single_t_evolution = []
                list_single_t_evolution.append(
                    2.0)  # I always start with TWO infected doctors!!

                for n in G.nodes(
                ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                    if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                      == "F"):
                        if G.node[n]['label'] != "Wunderink" and G.node[n][
                                "label"] != "Weiss":
                            rand = random.random()
                            if rand < prob_Immune:
                                G.node[n]["status"] = "Immune"

            #   print max_order

            ################# the dynamics starts:

                t = 1
                while t < cutting_day:  # loop over shifts, in order   just until cutting day (training segment)
                    for n in G.nodes():
                        if G.node[n]['type'] == "shift" and G.node[n][
                                'order'] == t:
                            flag_possible_infection = 0
                            for doctor in G.neighbors(
                                    n
                            ):  #first i check if any doctor is infected in this shift
                                if G.node[doctor]["status"] == "I":
                                    flag_possible_infection = 1

                            if flag_possible_infection:
                                for doctor in G.neighbors(
                                        n
                                ):  # then the doctors in that shift, gets infected with prob_infection
                                    if G.node[doctor]["status"] == "S":
                                        rand = random.random()
                                        if rand < prob_infection:
                                            G.node[doctor]["status"] = "I"
                                            list_I.append(
                                                G.node[doctor]["label"])

                    list_single_t_evolution.append(float(
                        len(list_I)))  #/(len(list_A)+len(list_F)))

                    t += 1

                ######## end t loop

                for n in G.nodes():
                    if G.node[n]['type'] != "shift":
                        dict_network_states[G.node[n]
                                            ["label"]] = G.node[n]["status"]

                list_dict_network_states.append(dict_network_states)

                # print "number infected at the cutting point:", len(list_I), list_I

                list_lists_t_evolutions.append(list_single_t_evolution)

                list_dist_fixed_parameters.append(
                    compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                        list_actual_evol_training, list_single_t_evolution))

                list_dist_abs_at_ending_point_fixed_parameters.append(
                    abs(list_single_t_evolution[-1] -
                        list_actual_evol_training[-1])
                )  # i save the distance at the ending point between the current simu and actual evol

            # print "distance at ending point:", abs(list_single_t_evolution[-1]-list_actual_evol_training[-1])

            ######## end loop Niter for the training fase

            list_pair_dist_std_delta_end = []

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_fixed_parameters)
            )  # average dist between the curves over Niter
            list_pair_dist_std_delta_end.append(
                numpy.std(list_dist_fixed_parameters))

            list_pair_dist_std_delta_end.append(
                numpy.mean(list_dist_abs_at_ending_point_fixed_parameters))

            if (
                    numpy.mean(list_dist_abs_at_ending_point_fixed_parameters)
            ) <= delta_end:  # i only consider situations close enough at the ending point

                dict_filenames_tot_distance[
                    output_file2] = list_pair_dist_std_delta_end

                dict_filenames_list_dict_network_states[
                    output_file2] = list_dict_network_states

            file2 = open(output_file2, 'at')
            for s in range(len(list_single_t_evolution)):
                list_fixed_t = []
                for iter in range(Niter_training):
                    list_fixed_t.append(list_lists_t_evolutions[iter][s])
                print >> file2, s, numpy.mean(list_fixed_t)
            file2.close()

            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

    list_order_dict = compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
        dict_filenames_tot_distance, "Infection_training", all_team,
        Niter_training)
    # it returns a list of tuples like this :  ('../Results/network_final_schedule_withTeam3_local/infection/Average_time_evolution_Infection_training_p0.7_Immune0.0_2iter_2012.dat', [2540.0, 208.0, 1.0])  the best set of parameters  being the fist one of the elements in the list.

    optimum_filename = list_order_dict[0][0]

    prob_infection = float(list_order_dict[0][0].split("_p")[1][0:3])
    prob_Immune = float(list_order_dict[0][0].split("_Immune")[1][0:3])

    #   raw_input()
    print "starting testing fase with:"
    print "p=", prob_infection, " and Pimmune=", prob_Immune

    #  i already know the optimum, now i run the dynamics with those values, starting from the average state on the cutting point, and test:

    list_dist_fixed_parameters = []
    list_dist_at_ending_point_fixed_parameters = []
    list_dist_abs_at_ending_point_fixed_parameters = []

    list_lists_t_evolutions = []

    for iter in range(Niter_testing):

        dict_dr_status_current_iter = dict_filenames_list_dict_network_states[
            optimum_filename][iter]

        #  print dict_dr_status_current_iter
        list_I = []  #list infected doctors
        list_Immune = []
        for node in G.nodes():
            if G.node[node]['type'] != "shift":
                label = G.node[node]['label']

                G.node[node]["status"] = "S"  #by default, all are susceptible

                G.node[node]["status"] = dict_dr_status_current_iter[label]
                if G.node[node]["status"] == "I":
                    list_I.append(G.node[node]["label"])
                elif G.node[node]["status"] == "Immune":
                    list_Immune.append(G.node[node]["label"])

        print "# I at the beginning of the testing fase:", len(list_I), float(
            len(list_I)) / 36., " and # Immune:", len(list_Immune), float(
                len(list_Immune)) / 36.

        #  print "     iter:",iter

        list_single_t_evolution = []
        list_single_t_evolution.append(len(list_I))

        t = cutting_day
        while t <= max_order:  # loop over shifts, in order   just until cutting day (training segment)

            for n in G.nodes():
                if G.node[n]['type'] == "shift" and G.node[n]['order'] == t:
                    flag_possible_infection = 0
                    for doctor in G.neighbors(
                            n
                    ):  #first i check if any doctor is infected in this shift
                        if G.node[doctor]["status"] == "I":
                            flag_possible_infection = 1

                    if flag_possible_infection:
                        for doctor in G.neighbors(
                                n
                        ):  # then the doctors in that shift, gets infected with prob_infection
                            if G.node[doctor]["status"] == "S":
                                rand = random.random()
                                if rand < prob_infection:
                                    G.node[doctor]["status"] = "I"
                                    list_I.append(G.node[doctor]["label"])

            list_single_t_evolution.append(float(len(list_I)))

            t += 1

        list_lists_t_evolutions.append(list_single_t_evolution)

        list_I = []  #list infected doctors
        list_Immune = []
        for node in G.nodes():
            if G.node[node]['type'] != "shift":
                label = G.node[node]['label']

                if G.node[node]["status"] == "I":
                    list_I.append(G.node[node]["label"])
                elif G.node[node]["status"] == "Immune":
                    list_Immune.append(G.node[node]["label"])

        print "  # I at the END of the testing fase:", len(list_I), float(
            len(list_I)) / 36., " and # Immune:", len(list_Immune), float(
                len(list_Immune)) / 36., "\n"

        list_dist_fixed_parameters.append(
            compare_real_evol_vs_simus_to_be_called.compare_two_curves(
                list_actual_evol_testing, list_single_t_evolution))

        list_dist_abs_at_ending_point_fixed_parameters.append(
            abs(list_single_t_evolution[-1] - list_actual_evol_testing[-1])
        )  # i save the distance at the ending point between the current simu and actual evol

        list_dist_at_ending_point_fixed_parameters.append(
            list_single_t_evolution[-1] - list_actual_evol_testing[-1]
        )  # i save the distance at the ending point between the current simu and actual evol

    ############### end loop Niter  for the testing

    num_valid_endings = 0.
    for item in list_dist_abs_at_ending_point_fixed_parameters:
        if item <= delta_end:  # i count how many realizations i get close enough at the ending point
            num_valid_endings += 1.

    print "average distance of the optimum in the testing segment:", numpy.mean(
        list_dist_fixed_parameters), numpy.std(
            list_dist_fixed_parameters), list_dist_fixed_parameters
    print "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter_testing, list_dist_abs_at_ending_point_fixed_parameters

    histograma_gral_negv_posit.histograma(
        list_dist_at_ending_point_fixed_parameters,
        "../Results/histogr_raw_distances_ending_test_train_infection_p" +
        str(prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" +
        str(Niter_training) + "iter_end_point.dat")

    output_file8 = "../Results/List_tot_distances_training_segment_infection_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_training) + "iter_end_point.dat"
    file8 = open(output_file8, 'wt')

    for item in list_dist_fixed_parameters:
        print >> file8, item
    file8.close()

    output_file9 = "../Results/List_distances_ending_training_segment_infection_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_training) + "iter_end_point.dat"
    file9 = open(output_file9, 'wt')

    for item in list_dist_abs_at_ending_point_fixed_parameters:
        print >> file9, item
    file9.close()

    output_file5 = dir + "Average_time_evolution_Infection_testing_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_testing) + "iter_2012.dat"

    file5 = open(output_file5, 'wt')
    for s in range(len(list_single_t_evolution)):
        list_fixed_t = []
        for iter in range(Niter_testing):
            list_fixed_t.append(list_lists_t_evolutions[iter][s])
        print >> file5, s + cutting_day, numpy.mean(list_fixed_t)
    #  print  s+cutting_day,numpy.mean(list_fixed_t)
    file5.close()

    print "written training segment file:", optimum_filename
    print "written testing segment file:", output_file5

    output_file10 = "../Results/Summary_results_training_segment_infection_p" + str(
        prob_infection) + "_" + "Immune" + str(prob_Immune) + "_" + str(
            Niter_training) + "iter.dat"
    file10 = open(output_file10, 'wt')

    print >> file10, "Summary results from train-testing persuasion with", Niter_training, Niter_testing, "iter (respectively), using all the individual cutting points as IC, and with values for the parameters:  prob_inf ", prob_infection, " prob immune: ", prob_Immune

    print >> file10, "average distance of the optimum in the testing segment:", numpy.mean(
        list_dist_fixed_parameters), numpy.std(
            list_dist_fixed_parameters), list_dist_fixed_parameters
    print >> file10, "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter_testing, list_dist_at_ending_point_fixed_parameters

    print >> file10, "written training segment file:", optimum_filename
    print >> file10, "written testing segment file:", output_file5

    file10.close()
def main(graph_name):

    G = nx.read_gml(graph_name)

    for_testing_fixed_set = "YES"  # when YES, fixed values param, to get all statistics on final distances etc
    # change the range for the parameters accordingly

    envelopes = "NO"

    Niter = 1000

    percent_envelope = 95.

    list_id_weekends_T3 = look_for_T3_weekends(
        G
    )  # T3 doesnt share fellows in the weekend  (but they are the exception)

    cutting_day = 175

    all_team = "NO"  # as adopters or not

    dir_real_data = '../Results/'

    dir = "../Results/weight_shifts/infection/"

    delta_end = 3.  # >= than + or -  dr difference at the end of the evolution (NO realization ends up closer than this!!!! if 2, i get and empty list!!!)
    Nbins = 20  # for the histogram of sum of distances

    if for_testing_fixed_set == "NO":
        output_file3 = "../Results/weight_shifts/Landscape_parameters_infection_memory_fixed_dose_thr_" + str(
            Niter) + "iterFIXED_Thr0.2_Imm0.0.dat"
        file3 = open(output_file3, 'wt')
        file3.close()

######################################################################################
#  I read the file of the actual evolution of the idea spreading in the hospital:   ##
######################################################################################

    if all_team == "YES":
        print "remember that now i use the file of adopters without fellows\n../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"
        exit()

    else:
        filename_actual_evol = "../Results/Actual_evolution_adopters_NO_fellows_only_attendings.dat"

    file1 = open(
        filename_actual_evol, 'r'
    )  ## i read the file:  list_dates_and_names_current_adopters.txt  (created with: extract_real_evolution_number_adopters.py)
    list_lines_file = file1.readlines()

    list_actual_evol = []
    for line in list_lines_file:  # [1:]:   # i exclude the first row

        num_adopters = float(line.split(" ")[1])
        list_actual_evol.append(num_adopters)

################################################################################

    prob_min = 0.3
    prob_max = 0.301
    delta_prob = 0.1

    prob_Immune_min = 0.00
    prob_Immune_max = 0.001
    delta_prob_Immune = 0.1

    dose_min = 0.7  # of a single encounter with an infected  (starting from zero doesnt make sense)
    dose_max = 0.701
    delta_dose = 0.01

    ##########  KEEP FIXED TO ONE
    infect_threshold_min = 1.00  # i can define the dose in units of the threshold
    infect_threshold_max = 1.001
    delta_infect_threshold = 0.1
    ############

    dict_filenames_tot_distance = {
    }  # i will save the filename as key and the tot distance from that curve to the original one

    prob_Immune = prob_Immune_min
    while prob_Immune <= prob_Immune_max:

        print "prom Immune:", prob_Immune

        prob_infection = prob_min
        while prob_infection <= prob_max:

            print "  p:", prob_infection

            infect_threshold = infect_threshold_min
            while infect_threshold <= infect_threshold_max:

                print "  threshold:", infect_threshold

                dose = dose_min
                while dose <= dose_max:

                    print "  dose:", dose

                    if for_testing_fixed_set == "YES":
                        output_file2 = dir + "Average_time_evolution_Infection_memory_train_test_p" + str(
                            prob_infection) + "_Immune" + str(
                                prob_Immune) + "_FIXED_threshold" + str(
                                    infect_threshold) + "_dose" + str(
                                        dose) + "_" + str(Niter) + "iter.dat"
                    else:
                        output_file2 = dir + "Average_time_evolution_Infection_memory_p" + str(
                            prob_infection) + "_Immune" + str(
                                prob_Immune) + "_FIXED_threshold" + str(
                                    infect_threshold) + "_dose" + str(
                                        dose) + "_" + str(Niter) + "iter.dat"

                    file2 = open(output_file2, 'wt')
                    file2.close()

                    num_shifts = 0
                    for n in G.nodes():
                        G.node[n]["status"] = "S"
                        G.node[n][
                            "infec_value"] = 0.  # when this value goes over the infect_threshold, the dr is infected
                        if G.node[n]['type'] == "shift":
                            num_shifts += 1

                    list_lists_t_evolutions = [
                    ]  # i create the empty list of list for the Niter temporal evolutions

                    list_dist_fixed_parameters = []
                    list_abs_dist_at_ending_point_fixed_parameters = []
                    list_dist_at_ending_point_fixed_parameters = []
                    list_final_num_infected = []

                    for iter in range(Niter):

                        #  print "     iter:",iter

                        list_I = []  #list infected doctors
                        list_ordering = []
                        list_s = []

                        ########### set I.C.

                        max_order = 0
                        for n in G.nodes():
                            G.node[n][
                                "status"] = "S"  # all nodes are Susceptible
                            if G.node[n]['type'] == "shift":
                                list_s.append(n)
                                if G.node[n]['order'] > max_order:
                                    max_order = G.node[n]['order']
                            else:
                                if G.node[n]['label'] == "Wunderink" or G.node[
                                        n]["label"] == "Weiss":
                                    G.node[n]["status"] = "I"
                                    G.node[n][
                                        "infec_value"] = infect_threshold + 1.
                                    list_I.append(G.node[n]['label'])

                        list_single_t_evolution = []
                        list_single_t_evolution.append(
                            2.0)  # I always start with TWO infected doctors!!

                        for n in G.nodes(
                        ):  # i make some DOCTORs INMUNE  (anyone except Weiss and Wunderink)
                            if (G.node[n]['type'] == "A") or (G.node[n]['type']
                                                              == "F"):
                                if G.node[n]['label'] != "Wunderink" and G.node[
                                        n]["label"] != "Weiss":
                                    rand = random.random()
                                    if rand < prob_Immune:
                                        G.node[n]["status"] = "Immune"

                        ################# the dynamics starts:

                        t = 1
                        while t <= max_order:  # loop over shifts, in order
                            for n in G.nodes():
                                if G.node[n]['type'] == "shift" and G.node[n][
                                        'order'] == t:
                                    shift_lenght = int(
                                        G.node[n]['shift_lenght'])

                                    if shift_lenght == 2 and n not in list_id_weekends_T3:
                                        shift_lenght = 1  # because during weekends, the fellow does rounds one day with Att1 and the other day with Att2.  (weekend shifts for T3 are two day long, with no sharing fellows)

                                    flag_possible_infection = 0
                                    for doctor in G.neighbors(
                                            n
                                    ):  #first i check if any doctor is infected in this shift
                                        if G.node[doctor]["status"] == "I":
                                            flag_possible_infection = 1

                                    if flag_possible_infection:
                                        for doctor in G.neighbors(
                                                n
                                        ):  # then the doctors in that shift, gets infected with prob_infection

                                            for i in range(shift_lenght):
                                                if G.node[doctor][
                                                        "status"] == "S":
                                                    rand = random.random()
                                                    if rand < prob_infection:  # with prob p the infection occurres

                                                        G.node[doctor][
                                                            "infec_value"] += dose  # and bumps the infection_value of that susceptible dr

                                                        if G.node[doctor][
                                                                "infec_value"] >= infect_threshold:  # becomes  infected

                                                            G.node[doctor][
                                                                "status"] = "I"
                                                            if G.node[doctor][
                                                                    "type"] == "A":  # fellows participate in the dynamics, but i only consider the attendings as real adopters
                                                                list_I.append(
                                                                    G.node[
                                                                        doctor]
                                                                    ["label"])

                        # for node in G.nodes():
                        #   if G.node[node]['type']!="shift":
                        #     print t, G.node[node]['label'], G.node[node]["infec_value"]
                        #raw_input()
                            list_single_t_evolution.append(float(len(list_I)))

                            t += 1
                            ######## end t loop

                        list_lists_t_evolutions.append(list_single_t_evolution)

                        list_dist_fixed_parameters.append(
                            compare_real_evol_vs_simus_to_be_called.
                            compare_two_curves(list_actual_evol,
                                               list_single_t_evolution))

                        list_abs_dist_at_ending_point_fixed_parameters.append(
                            abs(list_single_t_evolution[-1] -
                                list_actual_evol[-1])
                        )  # i save the distance at the ending point between the current simu and actual evol

                        list_dist_at_ending_point_fixed_parameters.append(
                            list_single_t_evolution[-1] - list_actual_evol[-1]
                        )  # i save the distance at the ending point between the current simu and actual evol

                        list_final_num_infected.append(
                            list_single_t_evolution[-1])

                        ######## end loop Niter

                    list_pair_dist_std_delta_end = []

                    list_pair_dist_std_delta_end.append(
                        numpy.mean(list_dist_fixed_parameters)
                    )  # average dist between the curves over Niter
                    list_pair_dist_std_delta_end.append(
                        numpy.std(list_dist_fixed_parameters))

                    list_pair_dist_std_delta_end.append(
                        numpy.mean(
                            list_abs_dist_at_ending_point_fixed_parameters))

                    if for_testing_fixed_set == "NO":
                        file3 = open(output_file3,
                                     'at')  # i print out the landscape
                        print >> file3, prob_infection, prob_Immune, numpy.mean(
                            list_abs_dist_at_ending_point_fixed_parameters
                        ), numpy.mean(list_dist_fixed_parameters), numpy.mean(
                            list_final_num_infected), numpy.std(
                                list_final_num_infected
                            ), numpy.std(list_final_num_infected) / numpy.mean(
                                list_final_num_infected)
                        file3.close()

                    if (
                            numpy.mean(
                                list_abs_dist_at_ending_point_fixed_parameters)
                    ) <= delta_end:  # i only consider situations close enough at the ending point

                        dict_filenames_tot_distance[
                            output_file2] = list_pair_dist_std_delta_end

                    file2 = open(output_file2, 'at')
                    for s in range(len(list_single_t_evolution)):
                        list_fixed_t = []
                        for iter in range(Niter):
                            list_fixed_t.append(
                                list_lists_t_evolutions[iter][s])
                        print >> file2, s, numpy.mean(list_fixed_t)
                    file2.close()

                    print "printed out: ", output_file2

                    if for_testing_fixed_set == "YES":

                        num_valid_endings = 0.
                        for item in list_abs_dist_at_ending_point_fixed_parameters:
                            if item <= delta_end:  # i count how many realizations i get close enough at the ending point
                                num_valid_endings += 1.

                        print "average distance of the optimum in the testing segment:", numpy.mean(
                            list_dist_fixed_parameters), numpy.std(
                                list_dist_fixed_parameters
                            ), list_dist_fixed_parameters, "\n"
                        print "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter, "mean ending dist:", numpy.mean(
                            list_dist_at_ending_point_fixed_parameters
                        ), "SD final dist", numpy.std(
                            list_dist_at_ending_point_fixed_parameters
                        ), list_dist_at_ending_point_fixed_parameters, "\n"

                        histogram_filename = "../Results/weight_shifts/histogr_raw_distances_ending_infection_memory_p" + str(
                            prob_infection
                        ) + "_Immune" + str(prob_Immune) + "_threshold" + str(
                            infect_threshold) + "_dose" + str(
                                dose) + "_" + str(Niter) + "iter_day" + str(
                                    cutting_day) + ".dat"
                        histograma_gral_negv_posit.histograma(
                            list_dist_at_ending_point_fixed_parameters,
                            histogram_filename)

                        histogram_filename2 = "../Results/weight_shifts/histogr_sum_dist_traject_infection_memory_p" + str(
                            prob_infection
                        ) + "_Immune" + str(prob_Immune) + "_threshold" + str(
                            infect_threshold) + "_dose" + str(
                                dose) + "_" + str(Niter) + "iter_day" + str(
                                    cutting_day) + ".dat"
                        histograma_bines_gral.histograma_bins(
                            list_dist_fixed_parameters, Nbins,
                            histogram_filename2)

                    output_file10 = "../Results/weight_shifts/Summary_results_training_segment_infection_memory_distrib_p" + str(
                        prob_infection) + "_" + "FIXED_Immune" + str(
                            prob_Immune) + "_FIXED_threshold" + str(
                                infect_threshold
                            ) + "_dose" + str(dose) + "_" + str(
                                Niter) + "iter_day" + str(cutting_day) + ".dat"
                    file10 = open(output_file10, 'wt')

                    print >> file10, "Summary results from train-testing infection with", Niter, "iter, and with values for the parameters:  prob_inf ", prob_infection, " prob immune: ", prob_Immune, "infect. threshold:", infect_threshold, "dose:", dose, "\n"

                    print >> file10, "average distance of the optimum in the testing segment:", numpy.mean(
                        list_dist_fixed_parameters), numpy.std(
                            list_dist_fixed_parameters
                        ), list_dist_fixed_parameters, "\n"
                    print >> file10, "fraction of realizations that end within delta_doctor:", num_valid_endings / Niter, "mean ending dist:", numpy.mean(
                        list_dist_at_ending_point_fixed_parameters
                    ), "SD final dist", numpy.std(
                        list_dist_at_ending_point_fixed_parameters
                    ), list_dist_at_ending_point_fixed_parameters, "\n"

                    print >> file10, "written optimum train_test evolution file:", output_file2
                    print >> file10, "written histogram file: ", histogram_filename

                    file10.close()

                    print "written Summary file: ", output_file10
                    print "written histogram file: ", histogram_filename

                    if envelopes == "YES":
                        calculate_envelope_set_curves.calculate_envelope(
                            list_lists_t_evolutions, percent_envelope,
                            "Infection_memory_fixed", [
                                prob_infection, prob_Immune, infect_threshold,
                                dose
                            ])

                    dose += delta_dose
                infect_threshold += delta_infect_threshold
            prob_infection += delta_prob
        prob_Immune += delta_prob_Immune

        if for_testing_fixed_set == "NO":  # only if i am exploring the whole landscape, i need to call this function, otherwise, i already know the optimum
            compare_real_evol_vs_simus_to_be_called.pick_minimum_same_end(
                dict_filenames_tot_distance, "Infection_memory", all_team,
                Niter, None)
            print "written landscape file:", output_file3