def run(argv=None):
"""Runs VCF to BigQuery pipeline."""
logging.info('Command: %s', ' '.join(argv or sys.argv))
parser = argparse.ArgumentParser()
parser.register('type', 'bool', lambda v: v.lower() == 'true')
command_line_options = [option() for option in _COMMAND_LINE_OPTIONS]
_add_parser_arguments(command_line_options, parser)
known_args, pipeline_args = parser.parse_known_args(argv)
_validate_args(command_line_options, known_args)
variant_merger = _get_variant_merge_strategy(known_args)
pipeline_mode = _get_pipeline_mode(known_args)
# Starts a pipeline to merge VCF headers in beam if the total files that
# match the input pattern exceeds _SMALL_DATA_THRESHOLD
_merge_headers(known_args, pipeline_args, pipeline_mode)
# Retrieve merged headers prior to launching the pipeline. This is needed
# since the BigQuery schema cannot yet be dynamically created based on input.
# See https://issues.apache.org/jira/browse/BEAM-2801.
header_fields = vcf_header_parser.get_vcf_headers(
known_args.representative_header_file)
counter_factory = metrics_util.CounterFactory()
processed_variant_factory = processed_variant.ProcessedVariantFactory(
header_fields,
known_args.split_alternate_allele_info_fields,
known_args.annotation_fields,
known_args.use_allele_num,
known_args.minimal_vep_alt_matching,
counter_factory)
pipeline_options = PipelineOptions(pipeline_args)
pipeline = beam.Pipeline(options=pipeline_options)
variants = _read_variants(pipeline, known_args)
variants |= 'FilterVariants' >> filter_variants.FilterVariants(
reference_names=known_args.reference_names)
if variant_merger:
variants |= (
'MergeVariants' >> merge_variants.MergeVariants(variant_merger))
proc_variants = variants | 'ProcessVaraints' >> beam.Map(
processed_variant_factory.create_processed_variant).\
with_output_types(processed_variant.ProcessedVariant)
_ = (proc_variants |
'VariantToBigQuery' >> variant_to_bigquery.VariantToBigQuery(
known_args.output_table,
header_fields,
variant_merger,
processed_variant_factory,
append=known_args.append,
allow_incompatible_records=known_args.allow_incompatible_records,
omit_empty_sample_calls=known_args.omit_empty_sample_calls))
result = pipeline.run()
result.wait_until_finish()
metrics_util.log_all_counters(result)
def run(argv=None):
# type: (List[str]) -> None
"""Runs VCF to BigQuery pipeline."""
logging.info('Command: %s', ' '.join(argv or sys.argv))
known_args, pipeline_args = vcf_to_bq_common.parse_args(
argv, _COMMAND_LINE_OPTIONS)
# Note VepRunner creates new input files, so it should be run before any
# other access to known_args.input_pattern.
if known_args.run_annotation_pipeline:
runner = vep_runner.create_runner_and_update_args(
known_args, pipeline_args)
runner.run_on_all_files()
runner.wait_until_done()
logging.info('Using VEP processed files: %s', known_args.input_pattern)
variant_merger = _get_variant_merge_strategy(known_args)
pipeline_mode = vcf_to_bq_common.get_pipeline_mode(
known_args.input_pattern, known_args.optimize_for_large_inputs)
# Starts a pipeline to merge VCF headers in beam if the total files that
# match the input pattern exceeds _SMALL_DATA_THRESHOLD
_merge_headers(known_args, pipeline_args, pipeline_mode)
# Retrieve merged headers prior to launching the pipeline. This is needed
# since the BigQuery schema cannot yet be dynamically created based on input.
# See https://issues.apache.org/jira/browse/BEAM-2801.
header_fields = vcf_header_parser.get_vcf_headers(
known_args.representative_header_file)
counter_factory = metrics_util.CounterFactory()
processed_variant_factory = processed_variant.ProcessedVariantFactory(
header_fields, known_args.split_alternate_allele_info_fields,
known_args.annotation_fields, known_args.use_allele_num,
known_args.minimal_vep_alt_matching, counter_factory)
partitioner = None
if known_args.optimize_for_large_inputs or known_args.partition_config_path:
partitioner = variant_partition.VariantPartition(
known_args.partition_config_path)
beam_pipeline_options = pipeline_options.PipelineOptions(pipeline_args)
pipeline = beam.Pipeline(options=beam_pipeline_options)
variants = _read_variants(pipeline, known_args)
variants |= 'FilterVariants' >> filter_variants.FilterVariants(
reference_names=known_args.reference_names)
if partitioner:
num_partitions = partitioner.get_num_partitions()
partitioned_variants = variants | 'PartitionVariants' >> beam.Partition(
partition_variants.PartitionVariants(partitioner), num_partitions)
variants = []
for i in range(num_partitions):
if partitioner.should_keep_partition(i):
variants.append(partitioned_variants[i])
else:
num_partitions -= 1
else:
# By default we don't partition the data, so we have only 1 partition.
num_partitions = 1
variants = [variants]
for i in range(num_partitions):
if variant_merger:
variants[i] |= ('MergeVariants' + str(i) >>
merge_variants.MergeVariants(variant_merger))
variants[i] |= (
'ProcessVaraints' + str(i) >>
beam.Map(processed_variant_factory.create_processed_variant).\
with_output_types(processed_variant.ProcessedVariant))
if partitioner and partitioner.should_flatten():
variants = [variants | 'FlattenPartitions' >> beam.Flatten()]
num_partitions = 1
for i in range(num_partitions):
table_suffix = ''
if partitioner and partitioner.get_partition_name(i):
table_suffix = '_' + partitioner.get_partition_name(i)
table_name = known_args.output_table + table_suffix
_ = (
variants[i] | 'VariantToBigQuery' + table_suffix >>
variant_to_bigquery.VariantToBigQuery(
table_name,
header_fields,
variant_merger,
processed_variant_factory,
append=known_args.append,
allow_incompatible_records=known_args.
allow_incompatible_records,
omit_empty_sample_calls=known_args.omit_empty_sample_calls,
num_bigquery_write_shards=known_args.num_bigquery_write_shards)
)
result = pipeline.run()
result.wait_until_finish()
metrics_util.log_all_counters(result)
def run(argv=None):
# type: (List[str]) -> None
"""Runs VCF to BigQuery pipeline."""
logging.info('Command: %s', ' '.join(argv or sys.argv))
known_args, pipeline_args = pipeline_common.parse_args(argv,
_COMMAND_LINE_OPTIONS)
if known_args.auto_flags_experiment:
_get_input_dimensions(known_args, pipeline_args)
annotated_vcf_pattern = _run_annotation_pipeline(known_args, pipeline_args)
all_patterns = (
[annotated_vcf_pattern] if annotated_vcf_pattern
else known_args.all_patterns)
variant_merger = _get_variant_merge_strategy(known_args)
pipeline_mode = pipeline_common.get_pipeline_mode(
all_patterns,
known_args.optimize_for_large_inputs)
# Starts a pipeline to merge VCF headers in beam if the total files that
# match the input pattern exceeds _SMALL_DATA_THRESHOLD
_merge_headers(known_args, pipeline_args,
pipeline_mode, annotated_vcf_pattern)
# Retrieve merged headers prior to launching the pipeline. This is needed
# since the BigQuery schema cannot yet be dynamically created based on input.
# See https://issues.apache.org/jira/browse/BEAM-2801.
header_fields = vcf_header_parser.get_vcf_headers(
known_args.representative_header_file)
counter_factory = metrics_util.CounterFactory()
processed_variant_factory = processed_variant.ProcessedVariantFactory(
header_fields,
known_args.split_alternate_allele_info_fields,
known_args.allow_malformed_records,
known_args.annotation_fields,
known_args.use_allele_num,
known_args.minimal_vep_alt_matching,
known_args.infer_annotation_types,
counter_factory)
partitioner = None
if ((known_args.optimize_for_large_inputs and variant_merger) or
known_args.partition_config_path):
partitioner = variant_partition.VariantPartition(
known_args.partition_config_path)
beam_pipeline_options = pipeline_options.PipelineOptions(pipeline_args)
pipeline = beam.Pipeline(options=beam_pipeline_options)
variants = _read_variants(all_patterns, pipeline, known_args, pipeline_mode)
variants |= 'FilterVariants' >> filter_variants.FilterVariants(
reference_names=known_args.reference_names)
if partitioner:
num_partitions = partitioner.get_num_partitions()
partitioned_variants = variants | 'PartitionVariants' >> beam.Partition(
partition_variants.PartitionVariants(partitioner), num_partitions)
variants = []
for i in range(num_partitions):
if partitioner.should_keep_partition(i):
variants.append(partitioned_variants[i])
else:
num_partitions -= 1
else:
# By default we don't partition the data, so we have only 1 partition.
num_partitions = 1
variants = [variants]
for i in range(num_partitions):
if variant_merger:
variants[i] |= ('MergeVariants' + str(i) >>
merge_variants.MergeVariants(variant_merger))
variants[i] |= (
'ProcessVariants' + str(i) >>
beam.Map(processed_variant_factory.create_processed_variant).\
with_output_types(processed_variant.ProcessedVariant))
if partitioner and partitioner.should_flatten():
variants = [variants | 'FlattenPartitions' >> beam.Flatten()]
num_partitions = 1
if known_args.output_table:
for i in range(num_partitions):
table_suffix = ''
if partitioner and partitioner.get_partition_name(i):
table_suffix = '_' + partitioner.get_partition_name(i)
table_name = known_args.output_table + table_suffix
_ = (variants[i] | 'VariantToBigQuery' + table_suffix >>
variant_to_bigquery.VariantToBigQuery(
table_name,
header_fields,
variant_merger,
processed_variant_factory,
append=known_args.append,
update_schema_on_append=known_args.update_schema_on_append,
allow_incompatible_records=known_args.allow_incompatible_records,
omit_empty_sample_calls=known_args.omit_empty_sample_calls,
num_bigquery_write_shards=known_args.num_bigquery_write_shards,
null_numeric_value_replacement=(
known_args.null_numeric_value_replacement)))
if known_args.output_avro_path:
# TODO(bashir2): Add an integration test that outputs to Avro files and
# also imports to BigQuery. Then import those Avro outputs using the bq
# tool and verify that the two tables are identical.
_ = (
variants | 'FlattenToOnePCollection' >> beam.Flatten()
| 'VariantToAvro' >>
variant_to_avro.VariantToAvroFiles(
known_args.output_avro_path,
header_fields,
processed_variant_factory,
variant_merger=variant_merger,
allow_incompatible_records=known_args.allow_incompatible_records,
omit_empty_sample_calls=known_args.omit_empty_sample_calls,
null_numeric_value_replacement=(
known_args.null_numeric_value_replacement))
)
result = pipeline.run()
result.wait_until_finish()
metrics_util.log_all_counters(result)