def _run_interface(self, runtime):
import nibabel as nb
import numpy as np
import nipy.modalities.fmri.glm as GLM
beta_nii = nb.load(self.inputs.beta)
if isdefined(self.inputs.mask):
mask = nb.load(self.inputs.mask).get_data() > 0
else:
mask = np.ones(beta_nii.shape[:3]) == 1
glm = GLM.GeneralLinearModel()
nii = nb.load(self.inputs.beta)
glm.beta = beta_nii.get_data().copy()[mask, :].T
glm.nvbeta = self.inputs.nvbeta
glm.s2 = nb.load(self.inputs.s2).get_data().copy()[mask]
glm.dof = self.inputs.dof
glm._axis = self.inputs.axis
glm._constants = self.inputs.constants
reg_names = self.inputs.reg_names
self._stat_maps = []
self._p_maps = []
self._z_maps = []
for contrast_def in self.inputs.contrasts:
name = contrast_def[0]
contrast = np.zeros(len(reg_names))
for i, reg_name in enumerate(reg_names):
if reg_name in contrast_def[2]:
idx = contrast_def[2].index(reg_name)
contrast[i] = contrast_def[3][idx]
est_contrast = glm.contrast(contrast)
stat_map = np.zeros(mask.shape)
stat_map[mask] = est_contrast.stat().T
stat_map_file = os.path.abspath(name + "_stat_map.nii")
nb.save(nb.Nifti1Image(stat_map, nii.affine), stat_map_file)
self._stat_maps.append(stat_map_file)
p_map = np.zeros(mask.shape)
p_map[mask] = est_contrast.pvalue().T
p_map_file = os.path.abspath(name + "_p_map.nii")
nb.save(nb.Nifti1Image(p_map, nii.affine), p_map_file)
self._p_maps.append(p_map_file)
z_map = np.zeros(mask.shape)
z_map[mask] = est_contrast.zscore().T
z_map_file = os.path.abspath(name + "_z_map.nii")
nb.save(nb.Nifti1Image(z_map, nii.affine), z_map_file)
self._z_maps.append(z_map_file)
return runtime
def _run_interface(self, runtime):
import nibabel as nb
import numpy as np
import nipy.modalities.fmri.glm as GLM
import nipy.modalities.fmri.design_matrix as dm
try:
BlockParadigm = dm.BlockParadigm
except AttributeError:
from nipy.modalities.fmri.experimental_paradigm import BlockParadigm
session_info = self.inputs.session_info
functional_runs = self.inputs.session_info[0]["scans"]
if isinstance(functional_runs, (str, bytes)):
functional_runs = [functional_runs]
nii = nb.load(functional_runs[0])
data = nii.get_data()
if isdefined(self.inputs.mask):
mask = nb.load(self.inputs.mask).get_data() > 0
else:
mask = np.ones(nii.shape[:3]) == 1
timeseries = data.copy()[mask, :]
del data
for functional_run in functional_runs[1:]:
nii = nb.load(functional_run, mmap=NUMPY_MMAP)
data = nii.get_data()
npdata = data.copy()
del data
timeseries = np.concatenate((timeseries, npdata[mask, :]), axis=1)
del npdata
nscans = timeseries.shape[1]
if "hpf" in list(session_info[0].keys()):
hpf = session_info[0]["hpf"]
drift_model = self.inputs.drift_model
else:
hpf = 0
drift_model = "Blank"
reg_names = []
for reg in session_info[0]["regress"]:
reg_names.append(reg["name"])
reg_vals = np.zeros((nscans, len(reg_names)))
for i in range(len(reg_names)):
reg_vals[:, i] = np.array(
session_info[0]["regress"][i]["val"]).reshape(1, -1)
frametimes = np.linspace(0, (nscans - 1) * self.inputs.TR, nscans)
conditions = []
onsets = []
duration = []
for i, cond in enumerate(session_info[0]["cond"]):
onsets += cond["onset"]
conditions += [cond["name"]] * len(cond["onset"])
if len(cond["duration"]) == 1:
duration += cond["duration"] * len(cond["onset"])
else:
duration += cond["duration"]
if conditions:
paradigm = BlockParadigm(con_id=conditions,
onset=onsets,
duration=duration)
else:
paradigm = None
design_matrix, self._reg_names = dm.dmtx_light(
frametimes,
paradigm,
drift_model=drift_model,
hfcut=hpf,
hrf_model=self.inputs.hrf_model,
add_regs=reg_vals,
add_reg_names=reg_names,
)
if self.inputs.normalize_design_matrix:
for i in range(len(self._reg_names) - 1):
design_matrix[:, i] = (
design_matrix[:, i] -
design_matrix[:, i].mean()) / design_matrix[:, i].std()
if self.inputs.plot_design_matrix:
import pylab
pylab.pcolor(design_matrix)
pylab.savefig("design_matrix.pdf")
pylab.close()
pylab.clf()
glm = GLM.GeneralLinearModel()
glm.fit(
timeseries.T,
design_matrix,
method=self.inputs.method,
model=self.inputs.model,
)
self._beta_file = os.path.abspath("beta.nii")
beta = np.zeros(mask.shape + (glm.beta.shape[0], ))
beta[mask, :] = glm.beta.T
nb.save(nb.Nifti1Image(beta, nii.affine), self._beta_file)
self._s2_file = os.path.abspath("s2.nii")
s2 = np.zeros(mask.shape)
s2[mask] = glm.s2
nb.save(nb.Nifti1Image(s2, nii.affine), self._s2_file)
if self.inputs.save_residuals:
explained = np.dot(design_matrix, glm.beta)
residuals = np.zeros(mask.shape + (nscans, ))
residuals[mask, :] = timeseries - explained.T
self._residuals_file = os.path.abspath("residuals.nii")
nb.save(nb.Nifti1Image(residuals, nii.affine),
self._residuals_file)
self._nvbeta = glm.nvbeta
self._dof = glm.dof
self._constants = glm._constants
self._axis = glm._axis
if self.inputs.model == "ar1":
self._a_file = os.path.abspath("a.nii")
a = np.zeros(mask.shape)
a[mask] = glm.a.squeeze()
nb.save(nb.Nifti1Image(a, nii.affine), self._a_file)
self._model = glm.model
self._method = glm.method
return runtime
