def create_workflow(files,
target_file,
subject_id,
TR,
slice_times,
norm_threshold=1,
num_components=5,
vol_fwhm=None,
surf_fwhm=None,
lowpass_freq=-1,
highpass_freq=-1,
subjects_dir=None,
sink_directory=os.getcwd(),
target_subject=['fsaverage3', 'fsaverage4'],
name='resting'):
wf = Workflow(name=name)
# Rename files in case they are named identically
name_unique = MapNode(Rename(format_string='rest_%(run)02d'),
iterfield=['in_file', 'run'],
name='rename')
name_unique.inputs.keep_ext = True
name_unique.inputs.run = list(range(1, len(files) + 1))
name_unique.inputs.in_file = files
realign = Node(nipy.SpaceTimeRealigner(), name="spacetime_realign")
realign.inputs.slice_times = slice_times
realign.inputs.tr = TR
realign.inputs.slice_info = 2
realign.plugin_args = {'sbatch_args': '-c%d' % 4}
# Compute TSNR on realigned data regressing polynomials up to order 2
tsnr = MapNode(TSNR(regress_poly=2), iterfield=['in_file'], name='tsnr')
wf.connect(realign, "out_file", tsnr, "in_file")
# Compute the median image across runs
calc_median = Node(CalculateMedian(), name='median')
wf.connect(tsnr, 'detrended_file', calc_median, 'in_files')
"""Segment and Register
"""
registration = create_reg_workflow(name='registration')
wf.connect(calc_median, 'median_file', registration, 'inputspec.mean_image')
registration.inputs.inputspec.subject_id = subject_id
registration.inputs.inputspec.subjects_dir = subjects_dir
registration.inputs.inputspec.target_image = target_file
"""Quantify TSNR in each freesurfer ROI
"""
get_roi_tsnr = MapNode(fs.SegStats(default_color_table=True),
iterfield=['in_file'], name='get_aparc_tsnr')
get_roi_tsnr.inputs.avgwf_txt_file = True
wf.connect(tsnr, 'tsnr_file', get_roi_tsnr, 'in_file')
wf.connect(registration, 'outputspec.aparc', get_roi_tsnr, 'segmentation_file')
"""Use :class:`nipype.algorithms.rapidart` to determine which of the
images in the functional series are outliers based on deviations in
intensity or movement.
"""
art = Node(interface=ArtifactDetect(), name="art")
art.inputs.use_differences = [True, True]
art.inputs.use_norm = True
art.inputs.norm_threshold = norm_threshold
art.inputs.zintensity_threshold = 9
art.inputs.mask_type = 'spm_global'
art.inputs.parameter_source = 'NiPy'
"""Here we are connecting all the nodes together. Notice that we add the merge node only if you choose
to use 4D. Also `get_vox_dims` function is passed along the input volume of normalise to set the optimal
voxel sizes.
"""
wf.connect([(name_unique, realign, [('out_file', 'in_file')]),
(realign, art, [('out_file', 'realigned_files')]),
(realign, art, [('par_file', 'realignment_parameters')]),
])
def selectindex(files, idx):
import numpy as np
from nipype.utils.filemanip import filename_to_list, list_to_filename
return list_to_filename(np.array(filename_to_list(files))[idx].tolist())
mask = Node(fsl.BET(), name='getmask')
mask.inputs.mask = True
wf.connect(calc_median, 'median_file', mask, 'in_file')
# get segmentation in normalized functional space
def merge_files(in1, in2):
out_files = filename_to_list(in1)
out_files.extend(filename_to_list(in2))
return out_files
# filter some noise
# Compute motion regressors
motreg = Node(Function(input_names=['motion_params', 'order',
'derivatives'],
output_names=['out_files'],
function=motion_regressors,
imports=imports),
name='getmotionregress')
wf.connect(realign, 'par_file', motreg, 'motion_params')
# Create a filter to remove motion and art confounds
createfilter1 = Node(Function(input_names=['motion_params', 'comp_norm',
'outliers', 'detrend_poly'],
output_names=['out_files'],
function=build_filter1,
imports=imports),
name='makemotionbasedfilter')
createfilter1.inputs.detrend_poly = 2
wf.connect(motreg, 'out_files', createfilter1, 'motion_params')
wf.connect(art, 'norm_files', createfilter1, 'comp_norm')
wf.connect(art, 'outlier_files', createfilter1, 'outliers')
filter1 = MapNode(fsl.GLM(out_f_name='F_mcart.nii.gz',
out_pf_name='pF_mcart.nii.gz',
demean=True),
iterfield=['in_file', 'design', 'out_res_name'],
name='filtermotion')
wf.connect(realign, 'out_file', filter1, 'in_file')
wf.connect(realign, ('out_file', rename, '_filtermotart'),
filter1, 'out_res_name')
wf.connect(createfilter1, 'out_files', filter1, 'design')
createfilter2 = MapNode(ACompCor(),
iterfield=['realigned_file', 'extra_regressors'],
name='makecompcorrfilter')
createfilter2.inputs.components_file = 'noise_components.txt'
createfilter2.inputs.num_components = num_components
wf.connect(createfilter1, 'out_files', createfilter2, 'extra_regressors')
wf.connect(filter1, 'out_res', createfilter2, 'realigned_file')
wf.connect(registration, ('outputspec.segmentation_files', selectindex, [0, 2]),
createfilter2, 'mask_file')
filter2 = MapNode(fsl.GLM(out_f_name='F.nii.gz',
out_pf_name='pF.nii.gz',
demean=True),
iterfield=['in_file', 'design', 'out_res_name'],
name='filter_noise_nosmooth')
wf.connect(filter1, 'out_res', filter2, 'in_file')
wf.connect(filter1, ('out_res', rename, '_cleaned'),
filter2, 'out_res_name')
wf.connect(createfilter2, 'components_file', filter2, 'design')
wf.connect(mask, 'mask_file', filter2, 'mask')
bandpass = Node(Function(input_names=['files', 'lowpass_freq',
'highpass_freq', 'fs'],
output_names=['out_files'],
function=bandpass_filter,
imports=imports),
name='bandpass_unsmooth')
bandpass.inputs.fs = 1. / TR
bandpass.inputs.highpass_freq = highpass_freq
bandpass.inputs.lowpass_freq = lowpass_freq
wf.connect(filter2, 'out_res', bandpass, 'files')
"""Smooth the functional data using
:class:`nipype.interfaces.fsl.IsotropicSmooth`.
"""
smooth = MapNode(interface=fsl.IsotropicSmooth(), name="smooth", iterfield=["in_file"])
smooth.inputs.fwhm = vol_fwhm
wf.connect(bandpass, 'out_files', smooth, 'in_file')
collector = Node(Merge(2), name='collect_streams')
wf.connect(smooth, 'out_file', collector, 'in1')
wf.connect(bandpass, 'out_files', collector, 'in2')
"""
Transform the remaining images. First to anatomical and then to target
"""
warpall = MapNode(ants.ApplyTransforms(), iterfield=['input_image'],
name='warpall')
warpall.inputs.input_image_type = 3
warpall.inputs.interpolation = 'Linear'
warpall.inputs.invert_transform_flags = [False, False]
warpall.terminal_output = 'file'
warpall.inputs.reference_image = target_file
warpall.inputs.args = '--float'
warpall.inputs.num_threads = 2
warpall.plugin_args = {'sbatch_args': '-c%d' % 2}
# transform to target
wf.connect(collector, 'out', warpall, 'input_image')
wf.connect(registration, 'outputspec.transforms', warpall, 'transforms')
mask_target = Node(fsl.ImageMaths(op_string='-bin'), name='target_mask')
wf.connect(registration, 'outputspec.anat2target', mask_target, 'in_file')
maskts = MapNode(fsl.ApplyMask(), iterfield=['in_file'], name='ts_masker')
wf.connect(warpall, 'output_image', maskts, 'in_file')
wf.connect(mask_target, 'out_file', maskts, 'mask_file')
# map to surface
# extract aparc+aseg ROIs
# extract subcortical ROIs
# extract target space ROIs
# combine subcortical and cortical rois into a single cifti file
#######
# Convert aparc to subject functional space
# Sample the average time series in aparc ROIs
sampleaparc = MapNode(freesurfer.SegStats(default_color_table=True),
iterfield=['in_file', 'summary_file',
'avgwf_txt_file'],
name='aparc_ts')
sampleaparc.inputs.segment_id = ([8] + list(range(10, 14)) + [17, 18, 26, 47] +
list(range(49, 55)) + [58] + list(range(1001, 1036)) +
list(range(2001, 2036)))
wf.connect(registration, 'outputspec.aparc',
sampleaparc, 'segmentation_file')
wf.connect(collector, 'out', sampleaparc, 'in_file')
def get_names(files, suffix):
"""Generate appropriate names for output files
"""
from nipype.utils.filemanip import (split_filename, filename_to_list,
list_to_filename)
import os
out_names = []
for filename in files:
path, name, _ = split_filename(filename)
out_names.append(os.path.join(path, name + suffix))
return list_to_filename(out_names)
wf.connect(collector, ('out', get_names, '_avgwf.txt'),
sampleaparc, 'avgwf_txt_file')
wf.connect(collector, ('out', get_names, '_summary.stats'),
sampleaparc, 'summary_file')
# Sample the time series onto the surface of the target surface. Performs
# sampling into left and right hemisphere
target = Node(IdentityInterface(fields=['target_subject']), name='target')
target.iterables = ('target_subject', filename_to_list(target_subject))
samplerlh = MapNode(freesurfer.SampleToSurface(),
iterfield=['source_file'],
name='sampler_lh')
samplerlh.inputs.sampling_method = "average"
samplerlh.inputs.sampling_range = (0.1, 0.9, 0.1)
samplerlh.inputs.sampling_units = "frac"
samplerlh.inputs.interp_method = "trilinear"
samplerlh.inputs.smooth_surf = surf_fwhm
# samplerlh.inputs.cortex_mask = True
samplerlh.inputs.out_type = 'niigz'
samplerlh.inputs.subjects_dir = subjects_dir
samplerrh = samplerlh.clone('sampler_rh')
samplerlh.inputs.hemi = 'lh'
wf.connect(collector, 'out', samplerlh, 'source_file')
wf.connect(registration, 'outputspec.out_reg_file', samplerlh, 'reg_file')
wf.connect(target, 'target_subject', samplerlh, 'target_subject')
samplerrh.set_input('hemi', 'rh')
wf.connect(collector, 'out', samplerrh, 'source_file')
wf.connect(registration, 'outputspec.out_reg_file', samplerrh, 'reg_file')
wf.connect(target, 'target_subject', samplerrh, 'target_subject')
# Combine left and right hemisphere to text file
combiner = MapNode(Function(input_names=['left', 'right'],
output_names=['out_file'],
function=combine_hemi,
imports=imports),
iterfield=['left', 'right'],
name="combiner")
wf.connect(samplerlh, 'out_file', combiner, 'left')
wf.connect(samplerrh, 'out_file', combiner, 'right')
# Sample the time series file for each subcortical roi
ts2txt = MapNode(Function(input_names=['timeseries_file', 'label_file',
'indices'],
output_names=['out_file'],
function=extract_subrois,
imports=imports),
iterfield=['timeseries_file'],
name='getsubcortts')
ts2txt.inputs.indices = [8] + list(range(10, 14)) + [17, 18, 26, 47] +\
list(range(49, 55)) + [58]
ts2txt.inputs.label_file = \
os.path.abspath(('OASIS-TRT-20_jointfusion_DKT31_CMA_labels_in_MNI152_'
'2mm_v2.nii.gz'))
wf.connect(maskts, 'out_file', ts2txt, 'timeseries_file')
######
substitutions = [('_target_subject_', ''),
('_filtermotart_cleaned_bp_trans_masked', ''),
('_filtermotart_cleaned_bp', ''),
]
substitutions += [("_smooth%d" % i, "") for i in range(11)[::-1]]
substitutions += [("_ts_masker%d" % i, "") for i in range(11)[::-1]]
substitutions += [("_getsubcortts%d" % i, "") for i in range(11)[::-1]]
substitutions += [("_combiner%d" % i, "") for i in range(11)[::-1]]
substitutions += [("_filtermotion%d" % i, "") for i in range(11)[::-1]]
substitutions += [("_filter_noise_nosmooth%d" % i, "") for i in range(11)[::-1]]
substitutions += [("_makecompcorfilter%d" % i, "") for i in range(11)[::-1]]
substitutions += [("_get_aparc_tsnr%d/" % i, "run%d_" % (i + 1)) for i in range(11)[::-1]]
substitutions += [("T1_out_brain_pve_0_maths_warped", "compcor_csf"),
("T1_out_brain_pve_1_maths_warped", "compcor_gm"),
("T1_out_brain_pve_2_maths_warped", "compcor_wm"),
("output_warped_image_maths", "target_brain_mask"),
("median_brain_mask", "native_brain_mask"),
("corr_", "")]
regex_subs = [('_combiner.*/sar', '/smooth/'),
('_combiner.*/ar', '/unsmooth/'),
('_aparc_ts.*/sar', '/smooth/'),
('_aparc_ts.*/ar', '/unsmooth/'),
('_getsubcortts.*/sar', '/smooth/'),
('_getsubcortts.*/ar', '/unsmooth/'),
('series/sar', 'series/smooth/'),
('series/ar', 'series/unsmooth/'),
('_inverse_transform./', ''),
]
# Save the relevant data into an output directory
datasink = Node(interface=DataSink(), name="datasink")
datasink.inputs.base_directory = sink_directory
datasink.inputs.container = subject_id
datasink.inputs.substitutions = substitutions
datasink.inputs.regexp_substitutions = regex_subs # (r'(/_.*(\d+/))', r'/run\2')
wf.connect(realign, 'par_file', datasink, 'resting.qa.motion')
wf.connect(art, 'norm_files', datasink, 'resting.qa.art.@norm')
wf.connect(art, 'intensity_files', datasink, 'resting.qa.art.@intensity')
wf.connect(art, 'outlier_files', datasink, 'resting.qa.art.@outlier_files')
wf.connect(registration, 'outputspec.segmentation_files', datasink, 'resting.mask_files')
wf.connect(registration, 'outputspec.anat2target', datasink, 'resting.qa.ants')
wf.connect(mask, 'mask_file', datasink, 'resting.mask_files.@brainmask')
wf.connect(mask_target, 'out_file', datasink, 'resting.mask_files.target')
wf.connect(filter1, 'out_f', datasink, 'resting.qa.compmaps.@mc_F')
wf.connect(filter1, 'out_pf', datasink, 'resting.qa.compmaps.@mc_pF')
wf.connect(filter2, 'out_f', datasink, 'resting.qa.compmaps')
wf.connect(filter2, 'out_pf', datasink, 'resting.qa.compmaps.@p')
wf.connect(registration, 'outputspec.min_cost_file', datasink, 'resting.qa.mincost')
wf.connect(tsnr, 'tsnr_file', datasink, 'resting.qa.tsnr.@map')
wf.connect([(get_roi_tsnr, datasink, [('avgwf_txt_file', 'resting.qa.tsnr'),
('summary_file', 'resting.qa.tsnr.@summary')])])
wf.connect(bandpass, 'out_files', datasink, 'resting.timeseries.@bandpassed')
wf.connect(smooth, 'out_file', datasink, 'resting.timeseries.@smoothed')
wf.connect(createfilter1, 'out_files',
datasink, 'resting.regress.@regressors')
wf.connect(createfilter2, 'components_file',
datasink, 'resting.regress.@compcorr')
wf.connect(maskts, 'out_file', datasink, 'resting.timeseries.target')
wf.connect(sampleaparc, 'summary_file',
datasink, 'resting.parcellations.aparc')
wf.connect(sampleaparc, 'avgwf_txt_file',
datasink, 'resting.parcellations.aparc.@avgwf')
wf.connect(ts2txt, 'out_file',
datasink, 'resting.parcellations.grayo.@subcortical')
datasink2 = Node(interface=DataSink(), name="datasink2")
datasink2.inputs.base_directory = sink_directory
datasink2.inputs.container = subject_id
datasink2.inputs.substitutions = substitutions
datasink2.inputs.regexp_substitutions = regex_subs # (r'(/_.*(\d+/))', r'/run\2')
wf.connect(combiner, 'out_file',
datasink2, 'resting.parcellations.grayo.@surface')
return wf
def analyze_openfmri_dataset(data_dir,
subject=None,
model_id=None,
task_id=None,
output_dir=None,
subj_prefix='*',
hpcutoff=120.,
use_derivatives=True,
fwhm=6.0,
subjects_dir=None,
target=None):
"""Analyzes an open fmri dataset
Parameters
----------
data_dir : str
Path to the base data directory
work_dir : str
Nipype working directory (defaults to cwd)
"""
"""
Load nipype workflows
"""
preproc = create_featreg_preproc(whichvol='first')
modelfit = create_modelfit_workflow()
fixed_fx = create_fixed_effects_flow()
if subjects_dir:
registration = create_fs_reg_workflow()
else:
registration = create_reg_workflow()
"""
Remove the plotting connection so that plot iterables don't propagate
to the model stage
"""
preproc.disconnect(preproc.get_node('plot_motion'), 'out_file',
preproc.get_node('outputspec'), 'motion_plots')
"""
Set up openfmri data specific components
"""
subjects = sorted([
path.split(os.path.sep)[-1]
for path in glob(os.path.join(data_dir, subj_prefix))
])
infosource = pe.Node(
niu.IdentityInterface(fields=['subject_id', 'model_id', 'task_id']),
name='infosource')
if len(subject) == 0:
infosource.iterables = [('subject_id', subjects),
('model_id', [model_id]), ('task_id', task_id)]
else:
infosource.iterables = [
('subject_id',
[subjects[subjects.index(subj)] for subj in subject]),
('model_id', [model_id]), ('task_id', task_id)
]
subjinfo = pe.Node(niu.Function(
input_names=['subject_id', 'base_dir', 'task_id', 'model_id'],
output_names=['run_id', 'conds', 'TR'],
function=get_subjectinfo),
name='subjectinfo')
subjinfo.inputs.base_dir = data_dir
"""
Return data components as anat, bold and behav
"""
contrast_file = os.path.join(data_dir, 'models', 'model%03d' % model_id,
'task_contrasts.txt')
has_contrast = os.path.exists(contrast_file)
if has_contrast:
datasource = pe.Node(nio.DataGrabber(
infields=['subject_id', 'run_id', 'task_id', 'model_id'],
outfields=['anat', 'bold', 'behav', 'contrasts']),
name='datasource')
else:
datasource = pe.Node(nio.DataGrabber(
infields=['subject_id', 'run_id', 'task_id', 'model_id'],
outfields=['anat', 'bold', 'behav']),
name='datasource')
datasource.inputs.base_directory = data_dir
datasource.inputs.template = '*'
if has_contrast:
datasource.inputs.field_template = {
'anat': '%s/anatomy/T1_001.nii.gz',
'bold': '%s/BOLD/task%03d_r*/bold.nii.gz',
'behav': ('%s/model/model%03d/onsets/task%03d_'
'run%03d/cond*.txt'),
'contrasts': ('models/model%03d/'
'task_contrasts.txt')
}
datasource.inputs.template_args = {
'anat': [['subject_id']],
'bold': [['subject_id', 'task_id']],
'behav': [['subject_id', 'model_id', 'task_id', 'run_id']],
'contrasts': [['model_id']]
}
else:
datasource.inputs.field_template = {
'anat': '%s/anatomy/T1_001.nii.gz',
'bold': '%s/BOLD/task%03d_r*/bold.nii.gz',
'behav': ('%s/model/model%03d/onsets/task%03d_'
'run%03d/cond*.txt')
}
datasource.inputs.template_args = {
'anat': [['subject_id']],
'bold': [['subject_id', 'task_id']],
'behav': [['subject_id', 'model_id', 'task_id', 'run_id']]
}
datasource.inputs.sort_filelist = True
"""
Create meta workflow
"""
wf = pe.Workflow(name='openfmri')
wf.connect(infosource, 'subject_id', subjinfo, 'subject_id')
wf.connect(infosource, 'model_id', subjinfo, 'model_id')
wf.connect(infosource, 'task_id', subjinfo, 'task_id')
wf.connect(infosource, 'subject_id', datasource, 'subject_id')
wf.connect(infosource, 'model_id', datasource, 'model_id')
wf.connect(infosource, 'task_id', datasource, 'task_id')
wf.connect(subjinfo, 'run_id', datasource, 'run_id')
wf.connect([
(datasource, preproc, [('bold', 'inputspec.func')]),
])
def get_highpass(TR, hpcutoff):
return hpcutoff / (2. * TR)
gethighpass = pe.Node(niu.Function(input_names=['TR', 'hpcutoff'],
output_names=['highpass'],
function=get_highpass),
name='gethighpass')
wf.connect(subjinfo, 'TR', gethighpass, 'TR')
wf.connect(gethighpass, 'highpass', preproc, 'inputspec.highpass')
"""
Setup a basic set of contrasts, a t-test per condition
"""
def get_contrasts(contrast_file, task_id, conds):
import numpy as np
import os
contrast_def = []
if os.path.exists(contrast_file):
with open(contrast_file, 'rt') as fp:
contrast_def.extend([
np.array(row.split()) for row in fp.readlines()
if row.strip()
])
contrasts = []
for row in contrast_def:
if row[0] != 'task%03d' % task_id:
continue
con = [
row[1], 'T', ['cond%03d' % (i + 1) for i in range(len(conds))],
row[2:].astype(float).tolist()
]
contrasts.append(con)
# add auto contrasts for each column
for i, cond in enumerate(conds):
con = [cond, 'T', ['cond%03d' % (i + 1)], [1]]
contrasts.append(con)
return contrasts
contrastgen = pe.Node(niu.Function(
input_names=['contrast_file', 'task_id', 'conds'],
output_names=['contrasts'],
function=get_contrasts),
name='contrastgen')
art = pe.MapNode(
interface=ra.ArtifactDetect(use_differences=[True, False],
use_norm=True,
norm_threshold=1,
zintensity_threshold=3,
parameter_source='FSL',
mask_type='file'),
iterfield=['realigned_files', 'realignment_parameters', 'mask_file'],
name="art")
modelspec = pe.Node(interface=model.SpecifyModel(), name="modelspec")
modelspec.inputs.input_units = 'secs'
def check_behav_list(behav, run_id, conds):
import numpy as np
num_conds = len(conds)
if isinstance(behav, (str, bytes)):
behav = [behav]
behav_array = np.array(behav).flatten()
num_elements = behav_array.shape[0]
return behav_array.reshape(int(num_elements / num_conds),
num_conds).tolist()
reshape_behav = pe.Node(niu.Function(
input_names=['behav', 'run_id', 'conds'],
output_names=['behav'],
function=check_behav_list),
name='reshape_behav')
wf.connect(subjinfo, 'TR', modelspec, 'time_repetition')
wf.connect(datasource, 'behav', reshape_behav, 'behav')
wf.connect(subjinfo, 'run_id', reshape_behav, 'run_id')
wf.connect(subjinfo, 'conds', reshape_behav, 'conds')
wf.connect(reshape_behav, 'behav', modelspec, 'event_files')
wf.connect(subjinfo, 'TR', modelfit, 'inputspec.interscan_interval')
wf.connect(subjinfo, 'conds', contrastgen, 'conds')
if has_contrast:
wf.connect(datasource, 'contrasts', contrastgen, 'contrast_file')
else:
contrastgen.inputs.contrast_file = ''
wf.connect(infosource, 'task_id', contrastgen, 'task_id')
wf.connect(contrastgen, 'contrasts', modelfit, 'inputspec.contrasts')
wf.connect([(preproc, art,
[('outputspec.motion_parameters', 'realignment_parameters'),
('outputspec.realigned_files', 'realigned_files'),
('outputspec.mask', 'mask_file')]),
(preproc, modelspec,
[('outputspec.highpassed_files', 'functional_runs'),
('outputspec.motion_parameters', 'realignment_parameters')]),
(art, modelspec, [('outlier_files', 'outlier_files')]),
(modelspec, modelfit, [('session_info',
'inputspec.session_info')]),
(preproc, modelfit, [('outputspec.highpassed_files',
'inputspec.functional_data')])])
# Comute TSNR on realigned data regressing polynomials upto order 2
tsnr = MapNode(TSNR(regress_poly=2), iterfield=['in_file'], name='tsnr')
wf.connect(preproc, "outputspec.realigned_files", tsnr, "in_file")
# Compute the median image across runs
calc_median = Node(CalculateMedian(), name='median')
wf.connect(tsnr, 'detrended_file', calc_median, 'in_files')
"""
Reorder the copes so that now it combines across runs
"""
def sort_copes(copes, varcopes, contrasts):
import numpy as np
if not isinstance(copes, list):
copes = [copes]
varcopes = [varcopes]
num_copes = len(contrasts)
n_runs = len(copes)
all_copes = np.array(copes).flatten()
all_varcopes = np.array(varcopes).flatten()
outcopes = all_copes.reshape(int(len(all_copes) / num_copes),
num_copes).T.tolist()
outvarcopes = all_varcopes.reshape(int(len(all_varcopes) / num_copes),
num_copes).T.tolist()
return outcopes, outvarcopes, n_runs
cope_sorter = pe.Node(niu.Function(
input_names=['copes', 'varcopes', 'contrasts'],
output_names=['copes', 'varcopes', 'n_runs'],
function=sort_copes),
name='cope_sorter')
pickfirst = lambda x: x[0]
wf.connect(contrastgen, 'contrasts', cope_sorter, 'contrasts')
wf.connect([(preproc, fixed_fx, [(('outputspec.mask', pickfirst),
'flameo.mask_file')]),
(modelfit, cope_sorter, [('outputspec.copes', 'copes')]),
(modelfit, cope_sorter, [('outputspec.varcopes', 'varcopes')]),
(cope_sorter, fixed_fx, [('copes', 'inputspec.copes'),
('varcopes', 'inputspec.varcopes'),
('n_runs', 'l2model.num_copes')]),
(modelfit, fixed_fx, [
('outputspec.dof_file', 'inputspec.dof_files'),
])])
wf.connect(calc_median, 'median_file', registration,
'inputspec.mean_image')
if subjects_dir:
wf.connect(infosource, 'subject_id', registration,
'inputspec.subject_id')
registration.inputs.inputspec.subjects_dir = subjects_dir
registration.inputs.inputspec.target_image = fsl.Info.standard_image(
'MNI152_T1_2mm_brain.nii.gz')
if target:
registration.inputs.inputspec.target_image = target
else:
wf.connect(datasource, 'anat', registration,
'inputspec.anatomical_image')
registration.inputs.inputspec.target_image = fsl.Info.standard_image(
'MNI152_T1_2mm.nii.gz')
registration.inputs.inputspec.target_image_brain = fsl.Info.standard_image(
'MNI152_T1_2mm_brain.nii.gz')
registration.inputs.inputspec.config_file = 'T1_2_MNI152_2mm'
def merge_files(copes, varcopes, zstats):
out_files = []
splits = []
out_files.extend(copes)
splits.append(len(copes))
out_files.extend(varcopes)
splits.append(len(varcopes))
out_files.extend(zstats)
splits.append(len(zstats))
return out_files, splits
mergefunc = pe.Node(niu.Function(
input_names=['copes', 'varcopes', 'zstats'],
output_names=['out_files', 'splits'],
function=merge_files),
name='merge_files')
wf.connect([(fixed_fx.get_node('outputspec'), mergefunc, [
('copes', 'copes'),
('varcopes', 'varcopes'),
('zstats', 'zstats'),
])])
wf.connect(mergefunc, 'out_files', registration, 'inputspec.source_files')
def split_files(in_files, splits):
copes = in_files[:splits[0]]
varcopes = in_files[splits[0]:(splits[0] + splits[1])]
zstats = in_files[(splits[0] + splits[1]):]
return copes, varcopes, zstats
splitfunc = pe.Node(niu.Function(
input_names=['in_files', 'splits'],
output_names=['copes', 'varcopes', 'zstats'],
function=split_files),
name='split_files')
wf.connect(mergefunc, 'splits', splitfunc, 'splits')
wf.connect(registration, 'outputspec.transformed_files', splitfunc,
'in_files')
if subjects_dir:
get_roi_mean = pe.MapNode(fs.SegStats(default_color_table=True),
iterfield=['in_file'],
name='get_aparc_means')
get_roi_mean.inputs.avgwf_txt_file = True
wf.connect(fixed_fx.get_node('outputspec'), 'copes', get_roi_mean,
'in_file')
wf.connect(registration, 'outputspec.aparc', get_roi_mean,
'segmentation_file')
get_roi_tsnr = pe.MapNode(fs.SegStats(default_color_table=True),
iterfield=['in_file'],
name='get_aparc_tsnr')
get_roi_tsnr.inputs.avgwf_txt_file = True
wf.connect(tsnr, 'tsnr_file', get_roi_tsnr, 'in_file')
wf.connect(registration, 'outputspec.aparc', get_roi_tsnr,
'segmentation_file')
"""
Connect to a datasink
"""
def get_subs(subject_id, conds, run_id, model_id, task_id):
subs = [('_subject_id_%s_' % subject_id, '')]
subs.append(('_model_id_%d' % model_id, 'model%03d' % model_id))
subs.append(('task_id_%d/' % task_id, '/task%03d_' % task_id))
subs.append(
('bold_dtype_mcf_mask_smooth_mask_gms_tempfilt_mean_warp', 'mean'))
subs.append(('bold_dtype_mcf_mask_smooth_mask_gms_tempfilt_mean_flirt',
'affine'))
for i in range(len(conds)):
subs.append(('_flameo%d/cope1.' % i, 'cope%02d.' % (i + 1)))
subs.append(('_flameo%d/varcope1.' % i, 'varcope%02d.' % (i + 1)))
subs.append(('_flameo%d/zstat1.' % i, 'zstat%02d.' % (i + 1)))
subs.append(('_flameo%d/tstat1.' % i, 'tstat%02d.' % (i + 1)))
subs.append(('_flameo%d/res4d.' % i, 'res4d%02d.' % (i + 1)))
subs.append(('_warpall%d/cope1_warp.' % i, 'cope%02d.' % (i + 1)))
subs.append(('_warpall%d/varcope1_warp.' % (len(conds) + i),
'varcope%02d.' % (i + 1)))
subs.append(('_warpall%d/zstat1_warp.' % (2 * len(conds) + i),
'zstat%02d.' % (i + 1)))
subs.append(('_warpall%d/cope1_trans.' % i, 'cope%02d.' % (i + 1)))
subs.append(('_warpall%d/varcope1_trans.' % (len(conds) + i),
'varcope%02d.' % (i + 1)))
subs.append(('_warpall%d/zstat1_trans.' % (2 * len(conds) + i),
'zstat%02d.' % (i + 1)))
subs.append(('__get_aparc_means%d/' % i, '/cope%02d_' % (i + 1)))
for i, run_num in enumerate(run_id):
subs.append(('__get_aparc_tsnr%d/' % i, '/run%02d_' % run_num))
subs.append(('__art%d/' % i, '/run%02d_' % run_num))
subs.append(('__dilatemask%d/' % i, '/run%02d_' % run_num))
subs.append(('__realign%d/' % i, '/run%02d_' % run_num))
subs.append(('__modelgen%d/' % i, '/run%02d_' % run_num))
subs.append(('/model%03d/task%03d/' % (model_id, task_id), '/'))
subs.append(('/model%03d/task%03d_' % (model_id, task_id), '/'))
subs.append(('_bold_dtype_mcf_bet_thresh_dil', '_mask'))
subs.append(('_output_warped_image', '_anat2target'))
subs.append(('median_flirt_brain_mask', 'median_brain_mask'))
subs.append(('median_bbreg_brain_mask', 'median_brain_mask'))
return subs
subsgen = pe.Node(niu.Function(
input_names=['subject_id', 'conds', 'run_id', 'model_id', 'task_id'],
output_names=['substitutions'],
function=get_subs),
name='subsgen')
wf.connect(subjinfo, 'run_id', subsgen, 'run_id')
datasink = pe.Node(interface=nio.DataSink(), name="datasink")
wf.connect(infosource, 'subject_id', datasink, 'container')
wf.connect(infosource, 'subject_id', subsgen, 'subject_id')
wf.connect(infosource, 'model_id', subsgen, 'model_id')
wf.connect(infosource, 'task_id', subsgen, 'task_id')
wf.connect(contrastgen, 'contrasts', subsgen, 'conds')
wf.connect(subsgen, 'substitutions', datasink, 'substitutions')
wf.connect([(fixed_fx.get_node('outputspec'), datasink,
[('res4d', 'res4d'), ('copes', 'copes'),
('varcopes', 'varcopes'), ('zstats', 'zstats'),
('tstats', 'tstats')])])
wf.connect([(modelfit.get_node('modelgen'), datasink, [
('design_cov', 'qa.model'),
('design_image', 'qa.model.@matrix_image'),
('design_file', 'qa.model.@matrix'),
])])
wf.connect([(preproc, datasink,
[('outputspec.motion_parameters', 'qa.motion'),
('outputspec.motion_plots', 'qa.motion.plots'),
('outputspec.mask', 'qa.mask')])])
wf.connect(registration, 'outputspec.mean2anat_mask', datasink,
'qa.mask.mean2anat')
wf.connect(art, 'norm_files', datasink, 'qa.art.@norm')
wf.connect(art, 'intensity_files', datasink, 'qa.art.@intensity')
wf.connect(art, 'outlier_files', datasink, 'qa.art.@outlier_files')
wf.connect(registration, 'outputspec.anat2target', datasink,
'qa.anat2target')
wf.connect(tsnr, 'tsnr_file', datasink, 'qa.tsnr.@map')
if subjects_dir:
wf.connect(registration, 'outputspec.min_cost_file', datasink,
'qa.mincost')
wf.connect([(get_roi_tsnr, datasink, [('avgwf_txt_file', 'qa.tsnr'),
('summary_file',
'qa.tsnr.@summary')])])
wf.connect([(get_roi_mean, datasink, [('avgwf_txt_file', 'copes.roi'),
('summary_file',
'copes.roi.@summary')])])
wf.connect([(splitfunc, datasink, [
('copes', 'copes.mni'),
('varcopes', 'varcopes.mni'),
('zstats', 'zstats.mni'),
])])
wf.connect(calc_median, 'median_file', datasink, 'mean')
wf.connect(registration, 'outputspec.transformed_mean', datasink,
'mean.mni')
wf.connect(registration, 'outputspec.func2anat_transform', datasink,
'xfm.mean2anat')
wf.connect(registration, 'outputspec.anat2target_transform', datasink,
'xfm.anat2target')
"""
Set processing parameters
"""
preproc.inputs.inputspec.fwhm = fwhm
gethighpass.inputs.hpcutoff = hpcutoff
modelspec.inputs.high_pass_filter_cutoff = hpcutoff
modelfit.inputs.inputspec.bases = {'dgamma': {'derivs': use_derivatives}}
modelfit.inputs.inputspec.model_serial_correlations = True
modelfit.inputs.inputspec.film_threshold = 1000
datasink.inputs.base_directory = output_dir
return wf