예제 #1
0
    Usage: `hapmap = homo_sapiens.HapmapII_GRCh37()` (note the
    parentheses).

    The Phase II HapMap Genetic map (lifted over to GRCh37) used in
    1000 Genomes. Please see the `README
    <ftp://ftp-trace.ncbi.nih.gov/1000genomes/ftp/technical/working/20110106_recombination_hotspots/README_hapmapII_GRCh37_map>`_
    for more details.
    """
    url = ("http://ftp-trace.ncbi.nih.gov/1000genomes/ftp/technical/working/"
           "20110106_recombination_hotspots/"
           "HapmapII_GRCh37_RecombinationHotspots.tar.gz")
    file_pattern = "genetic_map_GRCh37_{name}.txt"
    doi = "https://doi.org/10.1038/nature06258"


genetic_maps.register_genetic_map(HapmapII_GRCh37())


class Decode_2010_sex_averaged(genetic_maps.GeneticMap):
    """
    Usage: `decode = homo_sapiens.Decode_2010()` (note the
    parentheses).

    Decode fine scale genetic map from Kong, A et al. Fine scale
    recombination rate differences
    between sexes, populations and individuals. Nature (28 October 2010).
    (http://www.nature.com/nature/journal/v467/n7319/full/nature09525.html)
    Please see https://www.decode.com/addendum/ for more details.
    """
    url = ("http://sesame.uoregon.edu/~adkern/stdpopsim/decode/"
           "decode_2010_sex-averaged_map.tar.gz")
예제 #2
0

class Salome2012(genetic_maps.GeneticMap):
    """
    Genetic map from Salome 2012 averaged across population crosses.
    Please see this repo for details on how this was done: https://github.com/
    LohmuellerLab/arabidopsis_recomb_maps

    """

    url = ("http://www.eeb.ucla.edu/Faculty/Lohmueller/data/"
           "uploads/salome2012_maps.tar.gz")
    file_pattern = "arab_{name}_map_loess.txt"


genetic_maps.register_genetic_map(Salome2012())

###########################################################
#
# Genome definition
#
###########################################################

# Data for length information based on:
# https://www.arabidopsis.org/portals/genAnnotation/
#   gene_structural_annotation/agicomplete.jsp
# Lengths from TAIR 10 although its unclear what reference the genetic map used
#   -- follow up on this with Salome 2012 authors

_chromosome_data = """\
chr1 30427671
# Genetic maps
#
###########################################################


class Comeron2012_dm6(genetic_maps.GeneticMap):
    """
    Comeron et al. (2012) maps (lifted over to dm6) used in
    Currently needs a readme as to the lift over, etc.
    """
    url = ("http://sesame.uoregon.edu/~adkern/dmel_recombination_map/"
           "comeron2012_maps.tar.gz")
    file_pattern = "genetic_map_comeron2012_dm6_{name}.txt"


genetic_maps.register_genetic_map(Comeron2012_dm6())

###########################################################
#
# Genome definition
#
###########################################################

# List of chromosomes. Data for length information based on DM6,
# https://www.ncbi.nlm.nih.gov/genome/?term=drosophila+melanogaster.
# FIXME: add mean mutation and recombination rate data to this table.
_chromosome_data = """\
chrX   23542271
chr2L   23513712
chr2R   25286936
chr3L   28110227
예제 #4
0
    Usage: `hapmap = homo_sapiens.HapmapII_GRCh37()` (note the
    parentheses).

    The Phase II HapMap Genetic map (lifted over to GRCh37) used in
    1000 Genomes. Please see the `README
    <ftp://ftp-trace.ncbi.nih.gov/1000genomes/ftp/technical/working/20110106_recombination_hotspots/README_hapmapII_GRCh37_map>`_
    for more details.
    """
    url = (
        "http://ftp-trace.ncbi.nih.gov/1000genomes/ftp/technical/working/"
        "20110106_recombination_hotspots/"
        "HapmapII_GRCh37_RecombinationHotspots.tar.gz")
    file_pattern = "genetic_map_GRCh37_{name}.txt"


genetic_maps.register_genetic_map(HapmapII_GRCh37())


###########################################################
#
# Genome definition
#
###########################################################

# List of chromosomes.

# FIXME: add mean mutation rate data to this table.
# Name  Length  mean_recombination_rate mean_mutation_rate

# length information can be found here
# <http://hgdownload.soe.ucsc.edu/goldenPath/hg19/database/chromInfo.txt.gz>